ATE408413T1 - Pralmorelin-haltige nasentropfen-präparate - Google Patents

Pralmorelin-haltige nasentropfen-präparate

Info

Publication number: ATE408413T1
Authority: AT; Austria
Prior art keywords: pralmorelin; alanyl; preparation; preparations containing; nose drop
Prior art date: 2000-05-29

Application number

AT01932322T

Other languages

English (en)

Inventor

Akiko Ochiai

Yasutomi Kato

Hirokuni Kogetsu

Kiyoshi Maruyama

Original Assignee

Kaken Pharma Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-05-29

Filing date

2001-05-29

Publication date

2008-10-15

2001-05-29 Application filed by Kaken Pharma Co Ltd filed Critical Kaken Pharma Co Ltd

2008-10-15 Application granted granted Critical

2008-10-15 Publication of ATE408413T1 publication Critical patent/ATE408413T1/de

Links

HRNLPPBUBKMZMT-SSSXJSFTSA-N (2s)-6-amino-2-[[(2s)-2-[[(2s)-2-[[(2s)-2-[[(2r)-2-[[(2r)-2-aminopropanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]propanoyl]amino]-3-(1h-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamide Chemical compound C([C@H](NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](C)NC(=O)[C@@H](CC=1C=C2C=CC=CC2=CC=1)NC(=O)[C@H](N)C)C(=O)N[C@@H](CCCCN)C(N)=O)C1=CC=CC=C1 HRNLPPBUBKMZMT-SSSXJSFTSA-N 0.000 title abstract 4
108010085742 growth hormone-releasing peptide-2 Proteins 0.000 title abstract 4
229960000208 pralmorelin Drugs 0.000 title abstract 4
238000002360 preparation method Methods 0.000 title abstract 3
238000010521 absorption reaction Methods 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Otolaryngology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

AT01932322T 2000-05-29 2001-05-29 Pralmorelin-haltige nasentropfen-präparate ATE408413T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2000158676A JP3498041B2 (ja)	2000-05-29	2000-05-29	プラルモレリン含有点鼻用製剤

Publications (1)

Publication Number	Publication Date
ATE408413T1 true ATE408413T1 (de)	2008-10-15

Family

ID=18663108

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01932322T ATE408413T1 (de)	2000-05-29	2001-05-29	Pralmorelin-haltige nasentropfen-präparate

Country Status (7)

Country	Link
US (1)	US7008927B2 (de)
EP (1)	EP1297838B1 (de)
JP (1)	JP3498041B2 (de)
AT (1)	ATE408413T1 (de)
AU (1)	AU2001258859A1 (de)
DE (1)	DE60135845D1 (de)
WO (1)	WO2001091782A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7759312B2 (en) *	2005-03-11	2010-07-20	Endo Pharmaceuticals Solutions Inc.	Delivery of dry formulations of octreotide
CN101193626A (zh) *	2005-03-11	2008-06-04	益德威士医药股份有限公司	奥曲肽的受控释放制剂
BRPI0720729A2 (pt) *	2006-12-29	2014-04-08	Revance Therapeutics Inc	Moléculas de transporte que utilizam polipeptídeos hiv-tat de sequência inversa.
EP2303226B1 (de) *	2008-06-25	2016-03-23	Endo Pharmaceuticals Solutions Inc.	Verlängerte freisetzung von exenatid und anderen polypeptiden
CA2729139C (en)	2008-06-25	2016-07-26	Endo Pharmaceuticals Solutions Inc.	Octreotide implant having a release agent

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0080879B1 (de) *	1981-11-28	1986-10-01	Sunstar Kabushiki Kaisha	Stabilisiertes Interferon enthaltende pharmazeutische Zusammensetzung
JPS63303931A (ja)	1987-06-05	1988-12-12	Sumitomo Pharmaceut Co Ltd	経鼻投与用成長ホルモン放出活性物質製剤
IT1222395B (it)	1987-07-30	1990-09-05	Pierrel Spa	Composizione farmaceutica per somministrazione intranasale comprendente l'ormone ghrh,un agonista colinergico e/o un sale biliare
JP3179538B2 (ja) *	1990-12-11	2001-06-25	ノバルティスアクチエンゲゼルシャフト	安定なヒトカルシトニンの水性溶液
US5663146A (en) *	1991-08-22	1997-09-02	Administrators Of The Tulane Educational Fund	Polypeptide analogues having growth hormone releasing activity
WO1995011042A1 (en)	1993-10-21	1995-04-27	Hisamitsu Pharmaceutical Co., Inc.	Pernasal composition and pernasal preparation containing the same
JP2660484B2 (ja)	1994-04-12	1997-10-08	株式会社ミドリ十字	ヒト尿性トリプシンインヒビター含有液状製剤
JPH1045619A (ja)	1996-07-31	1998-02-17	Kaken Pharmaceut Co Ltd	成長ホルモン分泌促進ペプチド含有経口製剤
US5932548A (en) *	1998-06-03	1999-08-03	Deghenghi; Romano	Lysine containing peptides for treatment of heart disease
AU2001274601A1 (en)	2000-06-23	2002-01-02	Kaken Pharmaceutical Co., Ltd.	Preventives or remedies for heart failure
JP2002053489A (ja) *	2000-08-07	2002-02-19	Kaken Pharmaceut Co Ltd	筋肉増強剤・筋肉減衰の予防・治療剤

2000
- 2000-05-29 JP JP2000158676A patent/JP3498041B2/ja not_active Expired - Fee Related
2001
- 2001-05-29 WO PCT/JP2001/004503 patent/WO2001091782A1/ja not_active Ceased
- 2001-05-29 AT AT01932322T patent/ATE408413T1/de not_active IP Right Cessation
- 2001-05-29 AU AU2001258859A patent/AU2001258859A1/en not_active Abandoned
- 2001-05-29 US US10/296,791 patent/US7008927B2/en not_active Expired - Fee Related
- 2001-05-29 EP EP01932322A patent/EP1297838B1/de not_active Expired - Lifetime
- 2001-05-29 DE DE60135845T patent/DE60135845D1/de not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP1297838A4 (de)	2003-07-09
DE60135845D1 (de)	2008-10-30
JP2001335508A (ja)	2001-12-04
US7008927B2 (en)	2006-03-07
EP1297838B1 (de)	2008-09-17
US20030139347A1 (en)	2003-07-24
AU2001258859A1 (en)	2001-12-11
JP3498041B2 (ja)	2004-02-16
WO2001091782A1 (fr)	2001-12-06
EP1297838A1 (de)	2003-04-02

Legal Events

Date	Code	Title	Description
2009-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties
2010-08-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
CO5271759A1 (es)	2003-04-30	Formulacion en solucion que contiene una mezcla de disolventes
DK1091729T3 (da)	2008-07-21	Mikropartikelformulering til inhalation
DK1317419T3 (da)	2009-06-15	Cyanophenoxycarboxylsyre-forbindelser og sammensætninger til at levere aktive midler
BG106095A (bg)	2002-06-28	Нови лекарствени състави на базата на антихолинергично активни съединения и бета-миметици
ITMI912024A1 (it)	1993-01-22	Composizioni terapeutiche per somministrazione intranasale comprendenti ketorolac.
SE8804629D0 (sv)	1988-12-22	New therapeutically active compounds
UY27320A1 (es)	2003-02-28	Nuevas composiciones farmacéuticas
WO2002019969A3 (en)	2002-07-11	(5-(2-hydroxy-4-chlorobenzoyl) aminovaleric acid and salts thereof and compositions containing the same for delivering active agents
HRP20020404B1 (hr)	2007-08-31	Otopine koje sadrže epinastin
NO20023875D0 (no)	2002-08-15	Stabilt nasalt, oralt eller sublingualt anvendbart preparat
EP1852114A4 (de)	2008-08-13	Zusammensetzung mit dihomo-(gamma)-linolensäure (dgla) als aktivem inhaltsstoff
ATE440838T1 (de)	2009-09-15	Pharmazeutisch aktive sulfonylaminosäurederivate
SE0002476D0 (sv)	2000-06-30	New compounds
ATE408413T1 (de)	2008-10-15	Pralmorelin-haltige nasentropfen-präparate
NO912414D0 (no)	1991-06-20	Forbindelse med mavesyreinhiberende effekt og fremgangsmaate for dens fremstilling.
EP0647616A4 (de)	1995-08-16	Zink-tranexamat derivat.
ATE291421T1 (de)	2005-04-15	Pharmazeutische, ramipril enthaltende brauseformulierung
TR200302027T4 (tr)	2004-01-21	Hayvanlarda görülen parazit kaynaklı hastalıkarın tedavisine yönelik ilaç kompozisyonları
DK1220678T3 (da)	2007-07-09	Farmaceutiske præparater indeholdende kobber, salicylsyre og C-vitamin
AR026631A1 (es)	2003-02-19	''3-4-dihidroquinazolinas 5,6-disustituidas''
SE8101374L (sv)	1981-10-16	Kompositioner innehallande n,n-dietyl-m-toluamid
GT199900171A (es)	2001-03-28	Concentrado oral de sertralina.
SE9900177L (sv)	2000-07-22	Användning av en beredning innehållande myrsyra för framställning av ett läkemedel för behandling av vårtor, orsakade av Papillomavirus
WO2000026185A3 (en)	2000-08-10	Omeprazole solution and method of using same
WO2001045727A3 (en)	2002-06-06	Stabilized veterinary compositions comprising more than one antiviral agent