ATE408413T1 - Pralmorelin-haltige nasentropfen-präparate - Google Patents

Pralmorelin-haltige nasentropfen-präparate

Info

Publication number: ATE408413T1
Authority: AT; Austria
Prior art keywords: pralmorelin; alanyl; preparation; preparations containing; nose drop
Prior art date: 2000-05-29

Application number

AT01932322T

Other languages

English (en)

Inventor

Akiko Ochiai

Yasutomi Kato

Hirokuni Kogetsu

Kiyoshi Maruyama

Original Assignee

Kaken Pharma Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-05-29

Filing date

2001-05-29

Publication date

2008-10-15

2001-05-29 Application filed by Kaken Pharma Co Ltd filed Critical Kaken Pharma Co Ltd

2008-10-15 Application granted granted Critical

2008-10-15 Publication of ATE408413T1 publication Critical patent/ATE408413T1/de

Links

HRNLPPBUBKMZMT-SSSXJSFTSA-N (2s)-6-amino-2-[[(2s)-2-[[(2s)-2-[[(2s)-2-[[(2r)-2-[[(2r)-2-aminopropanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]propanoyl]amino]-3-(1h-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamide Chemical compound C([C@H](NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](C)NC(=O)[C@@H](CC=1C=C2C=CC=CC2=CC=1)NC(=O)[C@H](N)C)C(=O)N[C@@H](CCCCN)C(N)=O)C1=CC=CC=C1 HRNLPPBUBKMZMT-SSSXJSFTSA-N 0.000 title abstract 4
108010085742 growth hormone-releasing peptide-2 Proteins 0.000 title abstract 4
229960000208 pralmorelin Drugs 0.000 title abstract 4
238000002360 preparation method Methods 0.000 title abstract 3
238000010521 absorption reaction Methods 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Otolaryngology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

AT01932322T 2000-05-29 2001-05-29 Pralmorelin-haltige nasentropfen-präparate ATE408413T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2000158676A JP3498041B2 (ja)	2000-05-29	2000-05-29	プラルモレリン含有点鼻用製剤

Publications (1)

Publication Number	Publication Date
ATE408413T1 true ATE408413T1 (de)	2008-10-15

Family

ID=18663108

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01932322T ATE408413T1 (de)	2000-05-29	2001-05-29	Pralmorelin-haltige nasentropfen-präparate

Country Status (7)

Country	Link
US (1)	US7008927B2 (de)
EP (1)	EP1297838B1 (de)
JP (1)	JP3498041B2 (de)
AT (1)	ATE408413T1 (de)
AU (1)	AU2001258859A1 (de)
DE (1)	DE60135845D1 (de)
WO (1)	WO2001091782A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7759312B2 (en) *	2005-03-11	2010-07-20	Endo Pharmaceuticals Solutions Inc.	Delivery of dry formulations of octreotide
EP2457564A1 (de) *	2005-03-11	2012-05-30	Endo Pharmaceuticals Solutions Inc.	Octreotid-Formulierungen mit kontrollierter Freisetzung
WO2008082885A2 (en) *	2006-12-29	2008-07-10	Revance Therapeutics, Inc.	Transport molecules using reverse sequence hiv-tat polypeptides
WO2009158412A2 (en) *	2008-06-25	2009-12-30	Endo Pharmaceuticals Solutions Inc.	Sustained delivery of exenatide and other polypeptides
EP2317975B1 (de)	2008-06-25	2016-04-13	Endo Pharmaceuticals Solutions Inc.	Octreotid-implantat mit freisetzungsmittel

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3273597D1 (en) *	1981-11-28	1986-11-06	Sunstar Kk	Pharmaceutical composition containing interferon in stable state
JPS63303931A (ja)	1987-06-05	1988-12-12	Sumitomo Pharmaceut Co Ltd	経鼻投与用成長ホルモン放出活性物質製剤
IT1222395B (it)	1987-07-30	1990-09-05	Pierrel Spa	Composizione farmaceutica per somministrazione intranasale comprendente l'ormone ghrh,un agonista colinergico e/o un sale biliare
JP3179538B2 (ja)	1990-12-11	2001-06-25	ノバルティスアクチエンゲゼルシャフト	安定なヒトカルシトニンの水性溶液
US5663146A (en) *	1991-08-22	1997-09-02	Administrators Of The Tulane Educational Fund	Polypeptide analogues having growth hormone releasing activity
CN1098708C (zh) *	1993-10-21	2003-01-15	久光制药株式会社	经鼻吸收的组合物以及含有该组合物的经鼻吸收制剂
JP2660484B2 (ja) *	1994-04-12	1997-10-08	株式会社ミドリ十字	ヒト尿性トリプシンインヒビター含有液状製剤
JPH1045619A (ja) *	1996-07-31	1998-02-17	Kaken Pharmaceut Co Ltd	成長ホルモン分泌促進ペプチド含有経口製剤
US5932548A (en)	1998-06-03	1999-08-03	Deghenghi; Romano	Lysine containing peptides for treatment of heart disease
US6878689B2 (en) *	2000-06-23	2005-04-12	Kaken Pharmaceutical Co., Ltd.	Preventives or remedies for heart failure
JP2002053489A (ja) *	2000-08-07	2002-02-19	Kaken Pharmaceut Co Ltd	筋肉増強剤・筋肉減衰の予防・治療剤

2000
- 2000-05-29 JP JP2000158676A patent/JP3498041B2/ja not_active Expired - Fee Related
2001
- 2001-05-29 US US10/296,791 patent/US7008927B2/en not_active Expired - Fee Related
- 2001-05-29 AU AU2001258859A patent/AU2001258859A1/en not_active Abandoned
- 2001-05-29 EP EP01932322A patent/EP1297838B1/de not_active Expired - Lifetime
- 2001-05-29 DE DE60135845T patent/DE60135845D1/de not_active Expired - Fee Related
- 2001-05-29 WO PCT/JP2001/004503 patent/WO2001091782A1/ja not_active Ceased
- 2001-05-29 AT AT01932322T patent/ATE408413T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP1297838B1 (de)	2008-09-17
EP1297838A1 (de)	2003-04-02
DE60135845D1 (de)	2008-10-30
JP3498041B2 (ja)	2004-02-16
EP1297838A4 (de)	2003-07-09
JP2001335508A (ja)	2001-12-04
US20030139347A1 (en)	2003-07-24
US7008927B2 (en)	2006-03-07
AU2001258859A1 (en)	2001-12-11
WO2001091782A1 (fr)	2001-12-06

Legal Events

Date	Code	Title	Description
2009-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties
2010-08-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
CO5271759A1 (es)	2003-04-30	Formulacion en solucion que contiene una mezcla de disolventes
DK1091729T3 (da)	2008-07-21	Mikropartikelformulering til inhalation
DK1317419T3 (da)	2009-06-15	Cyanophenoxycarboxylsyre-forbindelser og sammensætninger til at levere aktive midler
BG106095A (bg)	2002-06-28	Нови лекарствени състави на базата на антихолинергично активни съединения и бета-миметици
ITMI912024A1 (it)	1993-01-22	Composizioni terapeutiche per somministrazione intranasale comprendenti ketorolac.
UY27320A1 (es)	2003-02-28	Nuevas composiciones farmacéuticas
WO2002019969A3 (en)	2002-07-11	(5-(2-hydroxy-4-chlorobenzoyl) aminovaleric acid and salts thereof and compositions containing the same for delivering active agents
PT96506A (pt)	1991-10-15	Processo para a preparacao de composicoes orais que incorporam como ingrediente activo pimobendano
HRP20020404B1 (hr)	2007-08-31	Otopine koje sadrže epinastin
NO20023875D0 (no)	2002-08-15	Stabilt nasalt, oralt eller sublingualt anvendbart preparat
DE59410151D1 (de)	2002-08-14	Feste Flupirtin enthaltende orale Darreichungsformen mit kontrollierter Wirkstoffabgabe
EP1852114A4 (de)	2008-08-13	Zusammensetzung mit dihomo-(gamma)-linolensäure (dgla) als aktivem inhaltsstoff
NZ507203A (en)	2003-03-28	Use of dexmedetomidine for ICU sedation
ATE440838T1 (de)	2009-09-15	Pharmazeutisch aktive sulfonylaminosäurederivate
SE0002476D0 (sv)	2000-06-30	New compounds
ATE408413T1 (de)	2008-10-15	Pralmorelin-haltige nasentropfen-präparate
NO912414L (no)	1991-08-06	Forbindelse med mavesyreinhiberende effekt og fremgangsmaate for dens fremstilling.
EP0647616A4 (de)	1995-08-16	Zink-tranexamat derivat.
DE50105710D1 (de)	2005-04-28	Pharmazeutische, ramipril enthaltende brauseformulierung
DK1220678T3 (da)	2007-07-09	Farmaceutiske præparater indeholdende kobber, salicylsyre og C-vitamin
UY26459A1 (es)	2001-06-29	3,4-dihidroquinazolinas 5,6-disustituidas
SE8101374L (sv)	1981-10-16	Kompositioner innehallande n,n-dietyl-m-toluamid
GT199900171A (es)	2001-03-28	Concentrado oral de sertralina.
BR0108727A (pt)	2002-11-05	Composição micelar para o tratamento de doenças parasìticas em animais, e, uso de uma composição
NO20013605L (no)	2001-09-20	Preparat for vorter