ATE408415T1 - Inhibitoren für die gefässneubildung - Google Patents

Inhibitoren für die gefässneubildung

Info

Publication number
ATE408415T1
ATE408415T1 AT99912129T AT99912129T ATE408415T1 AT E408415 T1 ATE408415 T1 AT E408415T1 AT 99912129 T AT99912129 T AT 99912129T AT 99912129 T AT99912129 T AT 99912129T AT E408415 T1 ATE408415 T1 AT E408415T1
Authority
AT
Austria
Prior art keywords
neovascularization
acid sequence
amino acid
hgf
inhibitors
Prior art date
Application number
AT99912129T
Other languages
English (en)
Inventor
Toshikazu Nakamura
Original Assignee
Toshikazu Nakamura
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toshikazu Nakamura filed Critical Toshikazu Nakamura
Application granted granted Critical
Publication of ATE408415T1 publication Critical patent/ATE408415T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1833—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT99912129T 1998-04-28 1999-04-06 Inhibitoren für die gefässneubildung ATE408415T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13468198 1998-04-28

Publications (1)

Publication Number Publication Date
ATE408415T1 true ATE408415T1 (de) 2008-10-15

Family

ID=15134093

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99912129T ATE408415T1 (de) 1998-04-28 1999-04-06 Inhibitoren für die gefässneubildung

Country Status (9)

Country Link
US (1) US20090023658A1 (de)
EP (1) EP1074264B1 (de)
JP (1) JP4094814B2 (de)
AT (1) ATE408415T1 (de)
CA (1) CA2327382C (de)
DE (1) DE69939586D1 (de)
DK (1) DK1074264T3 (de)
ES (1) ES2313777T3 (de)
WO (1) WO1999055361A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1320384B1 (de) 2000-08-28 2007-10-10 Damavand Wound AB Die synergistischen wirkungen von hgf und antibakterieller behandlung
US20030118585A1 (en) 2001-10-17 2003-06-26 Agy Therapeutics Use of protein biomolecular targets in the treatment and visualization of brain tumors
FR2831540B1 (fr) * 2001-10-31 2004-07-09 Inst Vaisseaux Et Du Sang Peptide isole du facteur de croissance hepatocytaire et ses variants, procede de preparation et utilisation en therapeutique en tant qu'agents antiangiogeniques
JP2003250549A (ja) * 2002-02-25 2003-09-09 Kringle Pharma Inc Ｎｋ４遺伝子または組換えｎｋ４蛋白質からなる医薬
AU2003270118A1 (en) * 2002-08-30 2004-03-19 F. Hoffmann-La Roche Ag Scatter factor/hepatocyte growth factor antagonist nk4 for the treatment of glioma
JP4716741B2 (ja) * 2004-01-27 2011-07-06 敏一 中村 糖鎖欠損型ＨＧＦα鎖部分蛋白質
WO2009125831A1 (ja) * 2008-04-11 2009-10-15 有限会社スリーピー Ｎｋ４に対するモノクローナル抗体
SG10201912684TA (en) * 2015-06-25 2020-03-30 Taiho Pharmaceutical Co Ltd Therapeutic agent for fibrosis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69133492T2 (de) * 1990-06-11 2006-08-10 Nakamura, Toshikazu Rekombinanter menschlicher Hepatozytwachstumsfaktor und Verfahren zu seiner Herstellung
US6566098B1 (en) * 1990-09-14 2003-05-20 The United States Of America As Represented By The Department Of Health And Human Services DNA encoding truncated hepatocyte growth factor variants
ATE355379T1 (de) * 1994-04-26 2006-03-15 Childrens Medical Center Angiostatin und verfahren zu seiner nutzung zur vermeidung der angiogenese
NZ307044A (en) * 1995-04-26 2002-03-01 Childrens Medical Center Angiostatin fragments with antiangiogenic activity
US5686292A (en) * 1995-06-02 1997-11-11 Genentech, Inc. Hepatocyte growth factor receptor antagonist antibodies and uses thereof
US6855685B2 (en) * 1995-10-24 2005-02-15 Toshikazu Nakamura Anti-cancer agent
JP2003250549A (ja) * 2002-02-25 2003-09-09 Kringle Pharma Inc Ｎｋ４遺伝子または組換えｎｋ４蛋白質からなる医薬

Also Published As

Publication number Publication date
EP1074264B1 (de) 2008-09-17
CA2327382A1 (en) 1999-11-04
WO1999055361A1 (en) 1999-11-04
DE69939586D1 (de) 2008-10-30
ES2313777T3 (es) 2009-03-01
DK1074264T3 (da) 2008-11-24
EP1074264A1 (de) 2001-02-07
US20090023658A1 (en) 2009-01-22
CA2327382C (en) 2012-12-18
JP4094814B2 (ja) 2008-06-04
EP1074264A4 (de) 2004-11-10

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