ATE408416T1 - Intrakraniale behandlung neuropsychiatrischer krankheiten mit clostridium neurotoxinen wie botulinus toxin - Google Patents
Intrakraniale behandlung neuropsychiatrischer krankheiten mit clostridium neurotoxinen wie botulinus toxinInfo
- Publication number
- ATE408416T1 ATE408416T1 AT03718383T AT03718383T ATE408416T1 AT E408416 T1 ATE408416 T1 AT E408416T1 AT 03718383 T AT03718383 T AT 03718383T AT 03718383 T AT03718383 T AT 03718383T AT E408416 T1 ATE408416 T1 AT E408416T1
- Authority
- AT
- Austria
- Prior art keywords
- neuropsychiatric diseases
- botulinus toxin
- intracranial treatment
- clostridium neurotoxins
- neurotoxins
- Prior art date
Links
- 238000007917 intracranial administration Methods 0.000 title abstract 2
- 239000002581 neurotoxin Substances 0.000 title abstract 2
- 231100000618 neurotoxin Toxicity 0.000 title abstract 2
- 241000193403 Clostridium Species 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 239000003053 toxin Substances 0.000 title 1
- 231100000765 toxin Toxicity 0.000 title 1
- 101710138657 Neurotoxin Proteins 0.000 abstract 1
- 108010057266 Type A Botulinum Toxins Proteins 0.000 abstract 1
- 229940094657 botulinum toxin type a Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000020016 psychiatric disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/143,078 US6921538B2 (en) | 2002-05-10 | 2002-05-10 | Therapeutic treatments for neuropsychiatric disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE408416T1 true ATE408416T1 (de) | 2008-10-15 |
Family
ID=29400026
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03718383T ATE408416T1 (de) | 2002-05-10 | 2003-04-11 | Intrakraniale behandlung neuropsychiatrischer krankheiten mit clostridium neurotoxinen wie botulinus toxin |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US6921538B2 (de) |
| EP (1) | EP1503790B1 (de) |
| JP (1) | JP4624777B2 (de) |
| AT (1) | ATE408416T1 (de) |
| AU (1) | AU2003221922B8 (de) |
| BR (1) | BR0309888A (de) |
| CA (1) | CA2484774C (de) |
| DE (1) | DE60323628D1 (de) |
| ES (1) | ES2314193T3 (de) |
| WO (1) | WO2003094955A1 (de) |
Families Citing this family (91)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8762065B2 (en) | 1998-08-05 | 2014-06-24 | Cyberonics, Inc. | Closed-loop feedback-driven neuromodulation |
| US9375573B2 (en) | 1998-08-05 | 2016-06-28 | Cyberonics, Inc. | Systems and methods for monitoring a patient's neurological disease state |
| US7209787B2 (en) | 1998-08-05 | 2007-04-24 | Bioneuronics Corporation | Apparatus and method for closed-loop intracranial stimulation for optimal control of neurological disease |
| US7747325B2 (en) | 1998-08-05 | 2010-06-29 | Neurovista Corporation | Systems and methods for monitoring a patient's neurological disease state |
| US9042988B2 (en) | 1998-08-05 | 2015-05-26 | Cyberonics, Inc. | Closed-loop vagus nerve stimulation |
| US7277758B2 (en) | 1998-08-05 | 2007-10-02 | Neurovista Corporation | Methods and systems for predicting future symptomatology in a patient suffering from a neurological or psychiatric disorder |
| US7403820B2 (en) | 1998-08-05 | 2008-07-22 | Neurovista Corporation | Closed-loop feedback-driven neuromodulation |
| US9415222B2 (en) | 1998-08-05 | 2016-08-16 | Cyberonics, Inc. | Monitoring an epilepsy disease state with a supervisory module |
| US7231254B2 (en) | 1998-08-05 | 2007-06-12 | Bioneuronics Corporation | Closed-loop feedback-driven neuromodulation |
| US7242984B2 (en) | 1998-08-05 | 2007-07-10 | Neurovista Corporation | Apparatus and method for closed-loop intracranial stimulation for optimal control of neurological disease |
| US7324851B1 (en) | 1998-08-05 | 2008-01-29 | Neurovista Corporation | Closed-loop feedback-driven neuromodulation |
| US7853329B2 (en) | 1998-08-05 | 2010-12-14 | Neurovista Corporation | Monitoring efficacy of neural modulation therapy |
| WO2001039664A1 (en) * | 1999-12-02 | 2001-06-07 | The General Hospital Corporation | Method and apparatus for measuring indices of brain activity |
| US6306403B1 (en) * | 2000-06-14 | 2001-10-23 | Allergan Sales, Inc. | Method for treating parkinson's disease with a botulinum toxin |
| US6921538B2 (en) * | 2002-05-10 | 2005-07-26 | Allergan, Inc. | Therapeutic treatments for neuropsychiatric disorders |
| US7393537B2 (en) | 2003-04-25 | 2008-07-01 | Allergan, Inc. | Botulinum toxin for treatment of obsessive compulsive finger biting disorder |
| US20040226556A1 (en) | 2003-05-13 | 2004-11-18 | Deem Mark E. | Apparatus for treating asthma using neurotoxin |
| US8734810B2 (en) * | 2003-10-29 | 2014-05-27 | Allergan, Inc. | Botulinum toxin treatments of neurological and neuropsychiatric disorders |
| US8609113B2 (en) | 2003-10-29 | 2013-12-17 | Allergan, Inc. | Botulinum toxin treatments of depression |
| US8609112B2 (en) | 2003-10-29 | 2013-12-17 | Allergan, Inc. | Botulinum toxin treatments of depression |
| US8617572B2 (en) | 2003-10-29 | 2013-12-31 | Allergan, Inc. | Botulinum toxin treatments of depression |
| US20050129677A1 (en) * | 2003-12-10 | 2005-06-16 | Shengwen Li | Lipid rafts and clostridial toxins |
| US20100266638A1 (en) | 2004-02-26 | 2010-10-21 | Allergan, Inc. | Headache treatment method |
| US7514088B2 (en) * | 2005-03-15 | 2009-04-07 | Allergan, Inc. | Multivalent Clostridial toxin derivatives and methods of their use |
| US7811584B2 (en) * | 2004-06-30 | 2010-10-12 | Allergan, Inc. | Multivalent clostridial toxins |
| ATE416191T1 (de) | 2004-09-01 | 2008-12-15 | Allergan Inc | Abbaubare clostridientoxine |
| US20060073208A1 (en) * | 2004-10-01 | 2006-04-06 | Allergan, Inc. | Cosmetic neurotoxin compositions and methods |
| EP1861419B1 (de) | 2005-03-15 | 2011-06-29 | Allergan, Inc. | Modifizierte clostridientoxine mit erhöhter targeting-kapazität für endogene clostridientoxin-rezeptorsysteme |
| EP1920248B1 (de) | 2005-04-05 | 2010-09-29 | Allergan, Inc. | Clostridientoxinaktivitätstests |
| US20150258183A1 (en) | 2006-06-07 | 2015-09-17 | Botulinum Toxin Research Associates, Inc. | Botulinum Toxin and the Treatment of Primary Disorders of Mood and Affect |
| US8926991B2 (en) * | 2005-06-14 | 2015-01-06 | Botulinum Toxin Research Associates, Inc. | Botulinum toxin and the treatment of primary disorders of mood and affect |
| WO2006138127A2 (en) * | 2005-06-14 | 2006-12-28 | Botulinum Toxin Research Associates, Inc. | Botulinum toxin and the treatment of primary disorders of mood and affect |
| US12433837B2 (en) | 2005-07-22 | 2025-10-07 | The Foundry, Llc | Systems and methods for delivery of a therapeutic agent |
| EP1906923B1 (de) | 2005-07-22 | 2018-01-24 | The Foundry, LLC | Systeme und verfahren zur freisetzung eines therapeutischen wirkstoffes |
| US9511210B2 (en) * | 2006-05-19 | 2016-12-06 | The Foundry, Llc | Apparatus for toxin delivery to the nasal cavity |
| US10052465B2 (en) | 2005-07-22 | 2018-08-21 | The Foundry, Llc | Methods and systems for toxin delivery to the nasal cavity |
| US8725243B2 (en) | 2005-12-28 | 2014-05-13 | Cyberonics, Inc. | Methods and systems for recommending an appropriate pharmacological treatment to a patient for managing epilepsy and other neurological disorders |
| US8868172B2 (en) | 2005-12-28 | 2014-10-21 | Cyberonics, Inc. | Methods and systems for recommending an appropriate action to a patient for managing epilepsy and other neurological disorders |
| TWI417301B (zh) * | 2006-02-21 | 2013-12-01 | Wyeth Corp | 對抗人類介白素-22(il-22)之抗體及其用途 |
| US20080027348A1 (en) | 2006-06-23 | 2008-01-31 | Neuro Vista Corporation | Minimally Invasive Monitoring Systems for Monitoring a Patient's Propensity for a Neurological Event |
| US8295934B2 (en) | 2006-11-14 | 2012-10-23 | Neurovista Corporation | Systems and methods of reducing artifact in neurological stimulation systems |
| WO2008080083A2 (en) * | 2006-12-22 | 2008-07-03 | Washington University | High performance imaging system for diffuse optical tomography and associated method of use |
| EP2126785A2 (de) | 2007-01-25 | 2009-12-02 | NeuroVista Corporation | Systeme und verfahren zur identifikation des kontra-iktalen zustands eines patienten |
| US20080183097A1 (en) | 2007-01-25 | 2008-07-31 | Leyde Kent W | Methods and Systems for Measuring a Subject's Susceptibility to a Seizure |
| US8036736B2 (en) | 2007-03-21 | 2011-10-11 | Neuro Vista Corporation | Implantable systems and methods for identifying a contra-ictal condition in a subject |
| US9788744B2 (en) | 2007-07-27 | 2017-10-17 | Cyberonics, Inc. | Systems for monitoring brain activity and patient advisory device |
| US20090171168A1 (en) | 2007-12-28 | 2009-07-02 | Leyde Kent W | Systems and Method for Recording Clinical Manifestations of a Seizure |
| US9259591B2 (en) | 2007-12-28 | 2016-02-16 | Cyberonics, Inc. | Housing for an implantable medical device |
| US8483831B1 (en) | 2008-02-15 | 2013-07-09 | Holaira, Inc. | System and method for bronchial dilation |
| US9480425B2 (en) * | 2008-04-17 | 2016-11-01 | Washington University | Task-less optical mapping of dynamic brain function using resting state functional connectivity |
| JP2011519699A (ja) | 2008-05-09 | 2011-07-14 | インノブアトイブエ プルモナルイ ソルウトイオンス,インコーポレイティッド | 気管支樹の治療のためのシステム、アセンブリ、及び方法 |
| WO2010013495A1 (ja) * | 2008-07-31 | 2010-02-04 | 財団法人化学及血清療法研究所 | 高度精製ボツリヌス毒素治療剤を有効成分として含有する薬学的組成物およびその利用 |
| US8849390B2 (en) | 2008-12-29 | 2014-09-30 | Cyberonics, Inc. | Processing for multi-channel signals |
| US8588933B2 (en) | 2009-01-09 | 2013-11-19 | Cyberonics, Inc. | Medical lead termination sleeve for implantable medical devices |
| US8786624B2 (en) | 2009-06-02 | 2014-07-22 | Cyberonics, Inc. | Processing for multi-channel signals |
| WO2011041483A2 (en) | 2009-09-30 | 2011-04-07 | Toxcure, Inc. | Use of botulinum neurotoxin to treat substance addictions |
| CA2779135C (en) | 2009-10-27 | 2018-09-04 | Innovative Pulmonary Solutions, Inc. | Delivery devices with coolable energy emitting assemblies |
| EP2842510B1 (de) | 2009-11-11 | 2022-08-24 | Nuvaira, Inc. | Vorrichtung zur Gewebebehandlung und Stenosekontrolleti |
| US8911439B2 (en) | 2009-11-11 | 2014-12-16 | Holaira, Inc. | Non-invasive and minimally invasive denervation methods and systems for performing the same |
| JP2011157331A (ja) * | 2010-02-03 | 2011-08-18 | Chemo-Sero-Therapeutic Research Inst | 高用量投与が可能なボツリヌス毒素製剤 |
| US9643019B2 (en) | 2010-02-12 | 2017-05-09 | Cyberonics, Inc. | Neurological monitoring and alerts |
| US8940308B2 (en) | 2010-03-30 | 2015-01-27 | Allergan, Inc. | Methods for treating depression |
| WO2012174123A1 (en) | 2011-06-13 | 2012-12-20 | Allergan, Inc. | Treatment of psychological trauma |
| EP2649985A1 (de) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Verbindungen zur Hemmung neuronaler Exozytose (III) |
| EP2649983A1 (de) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Verbindungen zur Hemmung neuronaler Exozytose (II) |
| KR102113994B1 (ko) | 2012-04-13 | 2020-05-25 | 루브리졸 어드밴스드 머티어리얼스, 인코포레이티드 | 신경세포 세포외배출(ii)을 억제하는 화합물 |
| EP2649984A1 (de) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Verbindungen zur Hemmung neuronaler Exozytose |
| US9005628B2 (en) | 2012-10-04 | 2015-04-14 | Dublin City University | Biotherapy for pain |
| EP2919807B1 (de) * | 2012-11-16 | 2018-07-11 | Finzi, Eric | Behandlung von posttraumatischen stresszuständen mit botulinumtoxin a |
| US9398933B2 (en) | 2012-12-27 | 2016-07-26 | Holaira, Inc. | Methods for improving drug efficacy including a combination of drug administration and nerve modulation |
| GB201312317D0 (en) | 2013-07-09 | 2013-08-21 | Syntaxin Ltd | Cationic neurotoxins |
| GB201313356D0 (en) * | 2013-07-26 | 2013-09-11 | Ucl Business Plc | Therapeutic Intervention |
| US9216210B2 (en) | 2013-12-23 | 2015-12-22 | Dublin City University | Multiprotease therapeutics for chronic pain |
| US9950194B2 (en) | 2014-09-09 | 2018-04-24 | Mevion Medical Systems, Inc. | Patient positioning system |
| DK3242884T3 (da) | 2015-01-09 | 2021-04-19 | Ipsen Bioinnovation Ltd | Kationiske neurotoksiner |
| WO2016149092A1 (en) | 2015-03-13 | 2016-09-22 | Allergan, Inc. | Improved injection paradigm for administration of botulinum toxins |
| GB201517450D0 (en) | 2015-10-02 | 2015-11-18 | Ipsen Biopharm Ltd | Method |
| GB201607901D0 (en) | 2016-05-05 | 2016-06-22 | Ipsen Biopharm Ltd | Chimeric neurotoxins |
| EP3263710A1 (de) | 2016-07-01 | 2018-01-03 | Ipsen Biopharm Limited | Herstellung von aktivierten clostridien-neurotoxinen |
| US20210277071A1 (en) | 2016-09-29 | 2021-09-09 | Ipsen Biopharm Limited | Hybrid neurotoxins |
| US10786010B2 (en) | 2017-12-15 | 2020-09-29 | Rai Strategic Holdings, Inc. | Aerosol delivery device with multiple aerosol delivery pathways |
| JP7186228B2 (ja) | 2018-02-26 | 2022-12-08 | イプセン バイオファーム リミテッド | 非細胞毒性プロテアーゼの注入を案内するための超音波の使用 |
| EP3850014A1 (de) | 2018-09-10 | 2021-07-21 | Academisch Ziekenhuis Leiden h.o.d.n. LUMC | Hemmung von moschus |
| CA3227431A1 (en) | 2019-10-18 | 2021-04-22 | Penland Foundation | Use of a botulinum toxin for treating autism and/or tolerance to narcotics |
| GB201917265D0 (en) | 2019-11-27 | 2020-01-08 | Univ Sheffield | Bonded neurotoxins |
| TWI854077B (zh) | 2019-12-20 | 2024-09-01 | 瑞士商葛德瑪控股公司 | 生產肉毒桿菌毒素的方法 |
| JP7772715B2 (ja) | 2020-04-17 | 2025-11-18 | ニューヨーク・ユニバーシティ | 治療用musk抗体 |
| CN113832069B (zh) * | 2020-11-30 | 2024-01-30 | 河南农业大学 | 丁酸梭菌及其应用 |
| GB202103372D0 (en) | 2021-03-11 | 2021-04-28 | Ipsen Biopharm Ltd | Modified clostridial neurotoxins |
| AU2023351434A1 (en) | 2022-09-30 | 2025-03-06 | Ipsen Biopharm Limited | Clostridial neurotoxin for use in a treatment of bladder pain syndrome |
| GB202318884D0 (en) | 2023-12-11 | 2024-01-24 | Ipsen Biopharm Ltd | Formulation |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4741902A (en) * | 1986-07-14 | 1988-05-03 | Haast William E | Compositions for treatment of neurological and related disorders |
| US5352447A (en) * | 1987-10-05 | 1994-10-04 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Immunotoxins for treatment of intracranial lesions and as adjunct to chemotherapy |
| DE4004573A1 (de) * | 1989-02-17 | 1990-08-23 | Tanabe Seiyaku Co | Neues versuchstier und seine herstellung |
| US5549884A (en) * | 1992-10-28 | 1996-08-27 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Rat or mouse exhibiting behaviors associated with human schizophrenia |
| US5562907A (en) * | 1993-05-14 | 1996-10-08 | Arnon; Stephen S. | Method to prevent side-effects and insensitivity to the therapeutic uses of toxins |
| US5545617A (en) * | 1993-11-12 | 1996-08-13 | The Schepens Eye Research Institute, Inc. | Therapeutic regulation of abnormal conjunctival goblet cell mucous secretion |
| US6974578B1 (en) * | 1993-12-28 | 2005-12-13 | Allergan, Inc. | Method for treating secretions and glands using botulinum toxin |
| EP1790352B1 (de) * | 1993-12-28 | 2008-07-09 | Allergan, Inc. | Verwendung von Botulinumtoxin für die Herstellung eines Arzneimittels zur Linderung von Rückenschmerzen |
| US5766605A (en) * | 1994-04-15 | 1998-06-16 | Mount Sinai School Of Medicine Of The City University Of New York | Treatment of autonomic nerve dysfunction with botulinum toxin |
| PT1086702E (pt) * | 1994-05-09 | 2005-08-31 | William J Binder | Neurotoxinas pre-sinapticas para tratamento da dor de cabeca devida a enxaqueca |
| WO1995032738A1 (en) * | 1994-05-31 | 1995-12-07 | Allergan, Inc. | Modification of clostridial toxins for use as transport proteins |
| SE9401965D0 (sv) * | 1994-06-07 | 1994-06-07 | Astra Ab | New compounds |
| GB9508204D0 (en) | 1995-04-21 | 1995-06-07 | Speywood Lab Ltd | A novel agent able to modify peripheral afferent function |
| US6071493A (en) * | 1996-09-20 | 2000-06-06 | Baylor College Of Medicine | Method of screening for an agent that inhibits mononuclear phagocyte-plaque component complex formation |
| US6272370B1 (en) * | 1998-08-07 | 2001-08-07 | The Regents Of University Of Minnesota | MR-visible medical device for neurological interventions using nonlinear magnetic stereotaxis and a method imaging |
| DE69911944T2 (de) * | 1998-04-29 | 2004-07-22 | Allergan, Inc., Irvine | Zusammensetzungen und methode zum verlängung der wirkung des clostridiumsneurotoxins |
| NZ510508A (en) * | 1998-09-15 | 2005-05-27 | Pharmexa As | Method for down-regulating osteoprotegerin ligand (OPGL) by enabling the production of antibodies against OPGL to treat osteoporosis |
| EP1128844B1 (de) * | 1998-10-27 | 2006-01-04 | Mayo Foundation For Medical Education And Research | Botulinumtoxine zur verstärkung der wundheilung |
| US6545126B1 (en) * | 1999-03-18 | 2003-04-08 | Wisconsin Alumni Research Foundation | Chimeric toxins |
| US6113915A (en) * | 1999-10-12 | 2000-09-05 | Allergan Sales, Inc. | Methods for treating pain |
| US6429189B1 (en) * | 1999-12-10 | 2002-08-06 | Botulinum Toxin Research Associates, Inc. | Cytotoxin (non-neurotoxin) for the treatment of human headache disorders and inflammatory diseases |
| US6524580B1 (en) * | 2000-02-15 | 2003-02-25 | Allergan Sales, Inc. | Method for treating thyroid disorders |
| US20010036943A1 (en) * | 2000-04-07 | 2001-11-01 | Coe Jotham W. | Pharmaceutical composition for treatment of acute, chronic pain and/or neuropathic pain and migraines |
| US6464986B1 (en) * | 2000-04-14 | 2002-10-15 | Allegan Sales, Inc. | Method for treating pain by peripheral administration of a neurotoxin |
| US6306423B1 (en) | 2000-06-02 | 2001-10-23 | Allergan Sales, Inc. | Neurotoxin implant |
| US6306403B1 (en) * | 2000-06-14 | 2001-10-23 | Allergan Sales, Inc. | Method for treating parkinson's disease with a botulinum toxin |
| US6827931B1 (en) * | 2000-10-20 | 2004-12-07 | Allergan, Inc. | Method for treating endocrine disorders |
| US6787517B1 (en) * | 2000-12-29 | 2004-09-07 | Allergan, Inc. | Agent and methods for treating pain |
| US20020192239A1 (en) * | 2001-01-09 | 2002-12-19 | Borodic Gary E. | Use of botulinum toxin for the treatment of chronic facial pain |
| US7063860B2 (en) * | 2001-08-13 | 2006-06-20 | University Of Pittsburgh | Application of lipid vehicles and use for drug delivery |
| US7255866B2 (en) * | 2001-09-17 | 2007-08-14 | Allergan, Inc. | Botulinum toxin therapy for fibromyalgia |
| US6623742B2 (en) * | 2001-09-17 | 2003-09-23 | Allergan, Inc. | Methods for treating fibromyalgia |
| DE10150415A1 (de) | 2001-10-11 | 2003-05-15 | Andres O Ceballos-Baumann | Arzneimittel zur Prophylaxe und Therapie von Depressionen |
| US6921538B2 (en) * | 2002-05-10 | 2005-07-26 | Allergan, Inc. | Therapeutic treatments for neuropsychiatric disorders |
| US7390496B2 (en) * | 2003-04-25 | 2008-06-24 | Allergan, Inc. | Therapeutic treatments for repetitive hand washing |
| US8734810B2 (en) * | 2003-10-29 | 2014-05-27 | Allergan, Inc. | Botulinum toxin treatments of neurological and neuropsychiatric disorders |
| US7270287B2 (en) * | 2004-01-06 | 2007-09-18 | Allergan, Inc. | Botulinum toxin treatment for kinesia |
| US7897147B2 (en) * | 2004-10-20 | 2011-03-01 | Allergan, Inc. | Treatment of premenstrual disorders |
-
2002
- 2002-05-10 US US10/143,078 patent/US6921538B2/en not_active Expired - Lifetime
-
2003
- 2003-04-11 JP JP2004503038A patent/JP4624777B2/ja not_active Expired - Fee Related
- 2003-04-11 WO PCT/US2003/011416 patent/WO2003094955A1/en not_active Ceased
- 2003-04-11 CA CA2484774A patent/CA2484774C/en not_active Expired - Lifetime
- 2003-04-11 ES ES03718383T patent/ES2314193T3/es not_active Expired - Lifetime
- 2003-04-11 EP EP03718383A patent/EP1503790B1/de not_active Expired - Lifetime
- 2003-04-11 DE DE60323628T patent/DE60323628D1/de not_active Expired - Lifetime
- 2003-04-11 BR BR0309888-5A patent/BR0309888A/pt not_active Application Discontinuation
- 2003-04-11 AU AU2003221922A patent/AU2003221922B8/en not_active Ceased
- 2003-04-11 AT AT03718383T patent/ATE408416T1/de not_active IP Right Cessation
-
2004
- 2004-03-22 US US10/806,972 patent/US7229626B2/en not_active Expired - Lifetime
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2007
- 2007-05-16 US US11/749,461 patent/US7811587B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20040180061A1 (en) | 2004-09-16 |
| US7229626B2 (en) | 2007-06-12 |
| US20030211121A1 (en) | 2003-11-13 |
| AU2003221922B8 (en) | 2009-06-18 |
| EP1503790A1 (de) | 2005-02-09 |
| US20070218085A1 (en) | 2007-09-20 |
| AU2003221922A1 (en) | 2003-11-11 |
| CA2484774A1 (en) | 2003-11-20 |
| JP4624777B2 (ja) | 2011-02-02 |
| BR0309888A (pt) | 2005-03-22 |
| DE60323628D1 (de) | 2008-10-30 |
| WO2003094955A1 (en) | 2003-11-20 |
| US7811587B2 (en) | 2010-10-12 |
| US6921538B2 (en) | 2005-07-26 |
| ES2314193T3 (es) | 2009-03-16 |
| JP2005530770A (ja) | 2005-10-13 |
| EP1503790B1 (de) | 2008-09-17 |
| CA2484774C (en) | 2012-07-10 |
| AU2003221922B2 (en) | 2006-09-28 |
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| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties | ||
| REN | Ceased due to non-payment of the annual fee |