|
US6727230B1
(en)
*
|
1994-03-25 |
2004-04-27 |
Coley Pharmaceutical Group, Inc. |
Immune stimulation by phosphorothioate oligonucleotide analogs
|
|
US6239116B1
(en)
*
|
1994-07-15 |
2001-05-29 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US6429199B1
(en)
*
|
1994-07-15 |
2002-08-06 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules for activating dendritic cells
|
|
US7935675B1
(en)
*
|
1994-07-15 |
2011-05-03 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US20030026782A1
(en)
*
|
1995-02-07 |
2003-02-06 |
Arthur M. Krieg |
Immunomodulatory oligonucleotides
|
|
US6207646B1
(en)
*
|
1994-07-15 |
2001-03-27 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
EP0855184A1
(de)
*
|
1997-01-23 |
1998-07-29 |
Grayson B. Dr. Lipford |
Pharmazeutisches Präparat das ein Polynukleotid und ein Antigen enthält, insbesondere zur Impfung
|
|
US6406705B1
(en)
*
|
1997-03-10 |
2002-06-18 |
University Of Iowa Research Foundation |
Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
|
|
GB9708917D0
(en)
*
|
1997-05-01 |
1997-06-25 |
Pfizer Ltd |
Compounds useful in therapy
|
|
US6218371B1
(en)
*
|
1998-04-03 |
2001-04-17 |
University Of Iowa Research Foundation |
Methods and products for stimulating the immune system using immunotherapeutic oligonucleotides and cytokines
|
|
WO1999058118A2
(en)
*
|
1998-05-14 |
1999-11-18 |
Cpg Immunopharmaceuticals Gmbh |
METHODS FOR REGULATING HEMATOPOIESIS USING CpG-OLIGONUCLEOTIDES
|
|
DK1733735T3
(en)
|
1998-05-22 |
2017-06-19 |
Ottawa Hospital Res Inst |
Methods and products for the induction of mucosal immunity
|
|
US20030022854A1
(en)
|
1998-06-25 |
2003-01-30 |
Dow Steven W. |
Vaccines using nucleic acid-lipid complexes
|
|
US6693086B1
(en)
*
|
1998-06-25 |
2004-02-17 |
National Jewish Medical And Research Center |
Systemic immune activation method using nucleic acid-lipid complexes
|
|
ES2572834T3
(es)
*
|
1999-02-17 |
2016-06-02 |
Csl Limited |
Complejos inmunogénicos y métodos relacionados con los mismos
|
|
IL148843A0
(en)
*
|
1999-09-25 |
2002-09-12 |
Univ Iowa Res Found |
Immunostimulatory nucleic acids
|
|
US6949520B1
(en)
*
|
1999-09-27 |
2005-09-27 |
Coley Pharmaceutical Group, Inc. |
Methods related to immunostimulatory nucleic acid-induced interferon
|
|
US7585847B2
(en)
*
|
2000-02-03 |
2009-09-08 |
Coley Pharmaceutical Group, Inc. |
Immunostimulatory nucleic acids for the treatment of asthma and allergy
|
|
US20040131628A1
(en)
*
|
2000-03-08 |
2004-07-08 |
Bratzler Robert L. |
Nucleic acids for the treatment of disorders associated with microorganisms
|
|
WO2001097843A2
(en)
|
2000-06-22 |
2001-12-27 |
University Of Iowa Research Foundation |
Methods for enhancing antibody-induced cell lysis and treating cancer
|
|
KR100917101B1
(ko)
*
|
2000-08-04 |
2009-09-15 |
도요 보세키 가부시키가이샤 |
플렉시블 금속적층체 및 그 제조방법
|
|
JP2005500806A
(ja)
*
|
2000-09-15 |
2005-01-13 |
コーリー ファーマシューティカル ゲーエムベーハー |
CpGに基づく免疫アゴニスト/免疫アンタゴニストの高スループットスクリーニングのためのプロセス
|
|
ES2307568T3
(es)
*
|
2000-12-08 |
2008-12-01 |
Coley Pharmaceutical Gmbh |
Acidos nucleicos de tipo cpg y metodos de uso de los mismos.
|
|
ES2314099T3
(es)
*
|
2001-08-17 |
2009-03-16 |
Coley Pharmaceutical Gmbh |
Oligonucleotidos inmunoestimulantes con motivos combinados con actividad mejorada.
|
|
AU2002324937B2
(en)
*
|
2001-09-07 |
2008-11-13 |
The Trustees Of Boston Univeristy |
Method and composition for treating immune complex associated disorders
|
|
EP1478371A4
(de)
*
|
2001-10-12 |
2007-11-07 |
Univ Iowa Res Found |
Verfahren und produkte zur verbesserung der immunantworten mit imidazochinolin-verbindungen
|
|
CA2480775C
(en)
|
2002-04-04 |
2016-05-31 |
Coley Pharmaceutical Gmbh |
Immunostimulatory g,u-containing oligoribonucleotides
|
|
US20040009949A1
(en)
*
|
2002-06-05 |
2004-01-15 |
Coley Pharmaceutical Group, Inc. |
Method for treating autoimmune or inflammatory diseases with combinations of inhibitory oligonucleotides and small molecule antagonists of immunostimulatory CpG nucleic acids
|
|
US7605138B2
(en)
*
|
2002-07-03 |
2009-10-20 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
|
US7807803B2
(en)
*
|
2002-07-03 |
2010-10-05 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
|
US7569553B2
(en)
*
|
2002-07-03 |
2009-08-04 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
|
US7576066B2
(en)
*
|
2002-07-03 |
2009-08-18 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
|
US20040053880A1
(en)
*
|
2002-07-03 |
2004-03-18 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
|
AR040996A1
(es)
*
|
2002-08-19 |
2005-04-27 |
Coley Pharm Group Inc |
Acidos nucleicos inmunoestimuladores
|
|
CA2503693A1
(en)
*
|
2002-10-29 |
2004-05-13 |
Coley Pharmaceutical Group, Ltd. |
Use of cpg oligonucleotides in the treatment of hepatitis c virus infection
|
|
JP2006512927A
(ja)
*
|
2002-12-11 |
2006-04-20 |
コーリー ファーマシューティカル グループ,インコーポレイテッド |
5’cpg核酸およびその使用方法
|
|
US7378524B2
(en)
*
|
2003-04-11 |
2008-05-27 |
Taigen Biotechnology Co., Ltd. |
Aminoquinoline compounds
|
|
US7183413B2
(en)
*
|
2003-04-11 |
2007-02-27 |
Taigen Biotechnology |
Aminoquinoline compounds
|
|
JP2007524615A
(ja)
*
|
2003-06-20 |
2007-08-30 |
コーリー ファーマシューティカル ゲーエムベーハー |
低分子トール様レセプター(tlr)アンタゴニスト
|
|
US20050013812A1
(en)
*
|
2003-07-14 |
2005-01-20 |
Dow Steven W. |
Vaccines using pattern recognition receptor-ligand:lipid complexes
|
|
AU2004275876B2
(en)
*
|
2003-09-25 |
2011-03-31 |
Coley Pharmaceutical Gmbh |
Nucleic acid-lipophilic conjugates
|
|
CN101454451A
(zh)
*
|
2003-10-30 |
2009-06-10 |
科勒制药有限公司 |
具有增强免疫刺激能力的c类寡核苷酸类似物
|
|
US20050239733A1
(en)
*
|
2003-10-31 |
2005-10-27 |
Coley Pharmaceutical Gmbh |
Sequence requirements for inhibitory oligonucleotides
|
|
US20050100983A1
(en)
*
|
2003-11-06 |
2005-05-12 |
Coley Pharmaceutical Gmbh |
Cell-free methods for identifying compounds that affect toll-like receptor 9 (TLR9) signaling
|
|
EP1720568A2
(de)
|
2004-02-19 |
2006-11-15 |
Coley Pharmaceutical Group, Inc. |
Immunstimulatorische virale rna-oligonucleotide
|
|
TWI235440B
(en)
*
|
2004-03-31 |
2005-07-01 |
Advanced Semiconductor Eng |
Method for making leadless semiconductor package
|
|
CA2572427A1
(en)
*
|
2004-07-18 |
2006-01-18 |
Heather L. Davis |
Immuno stimulating complex and oligonucleotide formulations for inducing enhanced interferon-gamma responses
|
|
MY159370A
(en)
*
|
2004-10-20 |
2016-12-30 |
Coley Pharm Group Inc |
Semi-soft-class immunostimulatory oligonucleotides
|
|
AU2006216493A1
(en)
*
|
2005-02-24 |
2006-08-31 |
Coley Pharmaceutical Gmbh |
Immunostimulatory oligonucleotides
|
|
EP1874325A2
(de)
*
|
2005-04-08 |
2008-01-09 |
Coley Pharmaceutical Group, Inc. |
Verfahren zur behandlung von durch infektionserkrankungen verschlimmertes asthma
|
|
EP1899467A2
(de)
*
|
2005-04-26 |
2008-03-19 |
Coley Pharmaceutical GmbH |
Modifizierte oligoribonukleotidanaloge mit verbesserter immunstimulierender aktivität
|
|
DE102006019144A1
(de)
*
|
2005-05-24 |
2006-11-30 |
Erco Leuchten Gmbh |
Leuchte
|
|
CN101268101A
(zh)
*
|
2005-07-07 |
2008-09-17 |
科利制药集团公司 |
用于癌症治疗的抗-CTLA-4抗体和含有CpG基序的合成寡脱氧核苷酸联合治疗
|
|
EA013468B1
(ru)
*
|
2005-09-16 |
2010-04-30 |
Коли Фармасьютикал Гмбх |
Иммуностимулирующая одноцепочечная рибонуклеиновая кислота с фосфодиэфирным остовом
|
|
WO2007031877A2
(en)
*
|
2005-09-16 |
2007-03-22 |
Coley Pharmaceutical Gmbh |
Modulation of immunostimulatory properties of short interfering ribonucleic acid (sirna) by nucleotide modification
|
|
WO2007059482A2
(en)
*
|
2005-11-14 |
2007-05-24 |
Cleveland Clinic Foundation |
Modulation of immune responses
|
|
ES2536103T3
(es)
*
|
2005-11-25 |
2015-05-20 |
Zoetis Belgium S.A. |
Oligorribonucleótidos inmunoestimuladores
|
|
PT1991678E
(pt)
*
|
2006-02-15 |
2015-11-25 |
Adiutide Pharmaceuticals Gmbh |
Composições e métodos para formulações de oligonucleótidos
|
|
CN101517082B
(zh)
|
2006-09-27 |
2014-01-22 |
科勒制药有限责任公司 |
具有增强的免疫刺激活性的含疏水性T类似物的CpG寡聚核苷酸类似物
|
|
WO2008057529A2
(en)
*
|
2006-11-06 |
2008-05-15 |
Coley Pharmaceutical Group, Inc. |
Peptide-based vaccine compositions to endogenous cholesteryl ester transfer protein (cetp)
|
|
EP2561868A1
(de)
|
2011-08-24 |
2013-02-27 |
Anton Bernhard Van Oosten |
Pharmazeutische Zusammensetzungen mit Hydroxychlorocin (HCQ), Curcumin, Piperin/BioPerin und Verwendungen in der Medizin
|
|
US9249103B2
(en)
*
|
2012-01-13 |
2016-02-02 |
Oregon Health & Science University |
Compounds, compositions and associated methods comprising 3-aryl quinolines
|
|
CA2987978C
(en)
*
|
2014-06-16 |
2022-08-16 |
Fundacion Para La Investigacion Medica Aplicada |
Novel compounds as dual inhibitors of histone methyltransferases and dna methyltransferases
|
|
WO2017163264A1
(en)
|
2016-03-21 |
2017-09-28 |
Council Of Scientific & Industrial Research |
Blocking toll-like receptor 9 signaling with small molecule antagonist
|
|
AU2018364807B2
(en)
*
|
2017-11-08 |
2022-05-19 |
Council Of Scientific & Industrial Research |
Purine based compounds as toll-like receptor 9 antagonist
|
|
WO2022191092A1
(ja)
*
|
2021-03-12 |
2022-09-15 |
国立大学法人東北大学 |
キノリン化合物、hnmt阻害剤、及びadhd、ナルコレプシー又はアルツハイマーの予防・治療剤
|