ATE411053T1 - Albuminkonjugate, die eine glucuron-verknüpfung enthalten - Google Patents

Albuminkonjugate, die eine glucuron-verknüpfung enthalten

Info

Publication number
ATE411053T1
ATE411053T1 AT04018855T AT04018855T ATE411053T1 AT E411053 T1 ATE411053 T1 AT E411053T1 AT 04018855 T AT04018855 T AT 04018855T AT 04018855 T AT04018855 T AT 04018855T AT E411053 T1 ATE411053 T1 AT E411053T1
Authority
AT
Austria
Prior art keywords
glucuron
albumine
link
conjugates containing
conjugates
Prior art date
Application number
AT04018855T
Other languages
English (en)
Inventor
Eva Frei
Hans-Hermann Schrenk
Christoph Fiehn
Paul Kremer
Andrea Breuer
Original Assignee
Deutsches Krebsforsch
Univ Ruprecht Karls Heidelberg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deutsches Krebsforsch, Univ Ruprecht Karls Heidelberg filed Critical Deutsches Krebsforsch
Application granted granted Critical
Publication of ATE411053T1 publication Critical patent/ATE411053T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT04018855T 2004-08-09 2004-08-09 Albuminkonjugate, die eine glucuron-verknüpfung enthalten ATE411053T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04018855A EP1625854B1 (de) 2004-08-09 2004-08-09 Albuminkonjugate, die eine Glucuron-Verknüpfung enthalten

Publications (1)

Publication Number Publication Date
ATE411053T1 true ATE411053T1 (de) 2008-10-15

Family

ID=34926104

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04018855T ATE411053T1 (de) 2004-08-09 2004-08-09 Albuminkonjugate, die eine glucuron-verknüpfung enthalten

Country Status (4)

Country Link
EP (1) EP1625854B1 (de)
AT (1) ATE411053T1 (de)
DE (1) DE602004017164D1 (de)
ES (1) ES2315600T3 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2111857A1 (de) 2008-04-25 2009-10-28 Acino AG Transdermales therapeutisches System zur Verabreichung von Fentanyl oder einem Analogstoff hiervon
EP2295046B1 (de) 2009-09-14 2012-12-19 Acino AG Transdermales therapeutisches System zur Verabreichung von Fentanyl oder einem Analogstoff davon
CA2799202C (en) * 2010-05-18 2016-07-05 Cerulean Pharma Inc. Compositions and methods for treatment of autoimmune and other diseases
CN106310290B (zh) * 2016-10-27 2019-08-23 深圳先进技术研究院 一种肿瘤靶向性热敏前药及其制备方法与应用
KR20190074310A (ko) 2016-11-08 2019-06-27 리제너론 파마슈티칼스 인코포레이티드 스테로이드 및 이의 단백질-접합체
CA3063871A1 (en) 2017-05-18 2018-11-22 Regeneron Pharmaceuticals, Inc. Cyclodextrin protein drug conjugates
JP7426931B2 (ja) 2017-11-07 2024-02-02 レゲネロン ファーマシューティカルス，インコーポレーテッド 抗体薬物コンジュゲートのための親水性リンカー
BR112020013492A2 (pt) 2018-01-08 2020-12-08 Regeneron Pharmaceuticals, Inc. Esteroides e conjugados de anticorpo dos mesmos
KR20210008008A (ko) 2018-05-09 2021-01-20 리제너론 파마슈티칼스 인코포레이티드 항-msr1 항체 및 이의 사용 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5828664A (ja) * 1981-08-13 1983-02-19 Eiken Kagaku Kk エストラジオ−ル−１７β−グルクロナイド測定用抗原およびその製造法
JPS5833162A (ja) * 1981-08-21 1983-02-26 Eiken Kagaku Kk エストリオ−ル−１６α−グルクロナイド測定用抗原およびその製造法
JPS6061596A (ja) * 1983-09-16 1985-04-09 Eiken Kagaku Kk 新規ステロイド化合物，その製造方法，及びその化合物からなる免疫化学的測定法によるエストラジオ−ル−３−サルフエ−ト−１７β−グルクロナイド測定用抗原
IT8922275A0 (it) * 1990-10-25 1989-11-06 Baldacci Lab Spa Nuovi derivati di corticosteroidi, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.
WO1993022334A1 (en) * 1992-05-04 1993-11-11 Sri International Pharmaceutical compositions and methods for colonic delivery of corticosteroids
RU95115547A (ru) * 1993-01-08 1997-06-10 Астра Актиеболаг (SE) Стероидные соединения, способы их получения и фармацевтический препарат
WO1995009177A1 (en) * 1993-09-29 1995-04-06 Nissin Shokuhin Kabushiki Kaisha 21-substituted steroid compound

Also Published As

Publication number Publication date
EP1625854A1 (de) 2006-02-15
DE602004017164D1 (de) 2008-11-27
EP1625854B1 (de) 2008-10-15
ES2315600T3 (es) 2009-04-01

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