ATE412655T1 - Als neue antiangiogene mittel geeignete thienopyridinphenylacetamide und derivate davon - Google Patents
Als neue antiangiogene mittel geeignete thienopyridinphenylacetamide und derivate davonInfo
- Publication number
- ATE412655T1 ATE412655T1 AT04769139T AT04769139T ATE412655T1 AT E412655 T1 ATE412655 T1 AT E412655T1 AT 04769139 T AT04769139 T AT 04769139T AT 04769139 T AT04769139 T AT 04769139T AT E412655 T1 ATE412655 T1 AT E412655T1
- Authority
- AT
- Austria
- Prior art keywords
- sup
- thienopyridinphenylacetamide
- derivatives
- compounds
- antiangiogenic agents
- Prior art date
Links
- 239000004037 angiogenesis inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000000651 prodrug Substances 0.000 abstract 2
- 229940002612 prodrug Drugs 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 230000003463 hyperproliferative effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Liquid Crystal Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49907703P | 2003-08-29 | 2003-08-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE412655T1 true ATE412655T1 (de) | 2008-11-15 |
Family
ID=34272772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04769139T ATE412655T1 (de) | 2003-08-29 | 2004-08-16 | Als neue antiangiogene mittel geeignete thienopyridinphenylacetamide und derivate davon |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7208500B2 (de) |
| EP (1) | EP1660504B1 (de) |
| JP (1) | JP2007504122A (de) |
| AT (1) | ATE412655T1 (de) |
| BR (1) | BRPI0413876A (de) |
| CA (1) | CA2536321A1 (de) |
| DE (1) | DE602004017479D1 (de) |
| ES (1) | ES2314444T3 (de) |
| MX (1) | MXPA06002296A (de) |
| WO (1) | WO2005021554A1 (de) |
Families Citing this family (36)
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| US7459562B2 (en) | 2004-04-23 | 2008-12-02 | Bristol-Myers Squibb Company | Monocyclic heterocycles as kinase inhibitors |
| TW200538453A (en) | 2004-04-26 | 2005-12-01 | Bristol Myers Squibb Co | Bicyclic heterocycles as kinase inhibitors |
| US7439246B2 (en) | 2004-06-28 | 2008-10-21 | Bristol-Myers Squibb Company | Fused heterocyclic kinase inhibitors |
| US7432373B2 (en) | 2004-06-28 | 2008-10-07 | Bristol-Meyers Squibb Company | Processes and intermediates useful for preparing fused heterocyclic kinase inhibitors |
| US20050288290A1 (en) | 2004-06-28 | 2005-12-29 | Borzilleri Robert M | Fused heterocyclic kinase inhibitors |
| CA2573538C (en) | 2004-07-30 | 2014-11-25 | Methylgene Inc. | Inhibitors of vegf receptor and hgf receptor signaling |
| CA2581516C (en) | 2004-10-12 | 2013-06-11 | Astrazeneca Ab | Quinazoline derivatives |
| ES2473341T3 (es) | 2005-05-20 | 2014-07-04 | Methylgene Inc | Inhibidores de la se�alizaci�n del receptor del VEGF y del receptor del HGF |
| JP5148499B2 (ja) * | 2005-05-20 | 2013-02-20 | メチルジーン インコーポレイテッド | Vegf受容体およびhgf受容体シグナル伝達の阻害剤 |
| WO2007035428A1 (en) * | 2005-09-15 | 2007-03-29 | Bristol-Myers Squibb Company | Met kinase inhibitors |
| US7547782B2 (en) | 2005-09-30 | 2009-06-16 | Bristol-Myers Squibb Company | Met kinase inhibitors |
| AR059246A1 (es) * | 2006-01-30 | 2008-03-19 | Array Biopharma Inc | Compuestos heterobiciclicos de tiofeno y metodos de uso |
| UY30183A1 (es) | 2006-03-02 | 2007-10-31 | Astrazeneca Ab | Derivados de quinolina |
| WO2007107005A1 (en) * | 2006-03-22 | 2007-09-27 | Methylgene, Inc. | Inhibitors of protein tyrosine kinase activity |
| WO2007117465A2 (en) | 2006-03-31 | 2007-10-18 | Abbott Laboratories | Indazole compounds |
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| WO2007134127A2 (en) * | 2006-05-09 | 2007-11-22 | Board Of Regents, The University Of Texas System | Agents for imaging apoptosis |
| US20110053931A1 (en) * | 2006-06-08 | 2011-03-03 | John Gaudino | Quinoline compounds and methods of use |
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| WO2009109035A1 (en) | 2008-03-05 | 2009-09-11 | Methylgene Inc. | Inhibitors of protein tyrosine kinase activity |
| CA2740746A1 (en) * | 2008-10-14 | 2010-04-22 | Ning Xi | Compounds comprising a spiro-ring and and methods of use |
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| EP2408300B1 (de) * | 2009-03-21 | 2016-05-11 | Sunshine Lake Pharma Co., Ltd. | Aminoesterderivate, salze daraus und verfahren zu ihrer verwendung |
| US8663210B2 (en) | 2009-05-13 | 2014-03-04 | Novian Health, Inc. | Methods and apparatus for performing interstitial laser therapy and interstitial brachytherapy |
| US9340555B2 (en) | 2009-09-03 | 2016-05-17 | Allergan, Inc. | Compounds as tyrosine kinase modulators |
| US8614234B2 (en) * | 2009-09-03 | 2013-12-24 | Allergan, Inc. | Compounds as tyrosine kinase modulators |
| WO2013044360A1 (en) * | 2011-09-30 | 2013-04-04 | Methylgene Inc. | Inhibitors of protein tyrosine kinase activity |
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| WO2013044361A1 (en) * | 2011-09-30 | 2013-04-04 | Methylgene Inc. | Inhibitors of protein tyrosine kinase activity |
| US10654808B2 (en) * | 2015-04-07 | 2020-05-19 | Guangdong Raynovent Biotech Co., Ltd. | Tyrosine kinase inhibitor and pharmaceutical composition comprising same |
| WO2018156946A1 (en) | 2017-02-24 | 2018-08-30 | Humanetics Corporation | Protecting tissue and mitigating injury from radiation-induced ionizing events |
| US11129894B2 (en) | 2017-09-29 | 2021-09-28 | - Humanetics Corporation | Sensitizing cells to proton radiation |
| CN111825605B (zh) * | 2019-04-19 | 2023-03-31 | 中国科学院上海药物研究所 | 芳基酮酰胺类化合物及其制备方法和用途 |
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-
2004
- 2004-08-16 CA CA002536321A patent/CA2536321A1/en not_active Abandoned
- 2004-08-16 DE DE602004017479T patent/DE602004017479D1/de not_active Expired - Lifetime
- 2004-08-16 AT AT04769139T patent/ATE412655T1/de not_active IP Right Cessation
- 2004-08-16 WO PCT/IB2004/002688 patent/WO2005021554A1/en not_active Ceased
- 2004-08-16 BR BRPI0413876-7A patent/BRPI0413876A/pt not_active IP Right Cessation
- 2004-08-16 MX MXPA06002296A patent/MXPA06002296A/es unknown
- 2004-08-16 ES ES04769139T patent/ES2314444T3/es not_active Expired - Lifetime
- 2004-08-16 JP JP2006524445A patent/JP2007504122A/ja not_active Withdrawn
- 2004-08-16 EP EP04769139A patent/EP1660504B1/de not_active Expired - Lifetime
- 2004-08-26 US US10/928,674 patent/US7208500B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE602004017479D1 (de) | 2008-12-11 |
| BRPI0413876A (pt) | 2006-10-24 |
| US7208500B2 (en) | 2007-04-24 |
| WO2005021554A1 (en) | 2005-03-10 |
| EP1660504B1 (de) | 2008-10-29 |
| US20050090509A1 (en) | 2005-04-28 |
| EP1660504A1 (de) | 2006-05-31 |
| ES2314444T3 (es) | 2009-03-16 |
| JP2007504122A (ja) | 2007-03-01 |
| CA2536321A1 (en) | 2005-03-10 |
| MXPA06002296A (es) | 2006-05-22 |
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