ATE412766T1 - Verfahren zur herstellung von herzmuskelzellen und verfahren zur suche von behandlungen von herzerkrankungen - Google Patents

Verfahren zur herstellung von herzmuskelzellen und verfahren zur suche von behandlungen von herzerkrankungen

Info

Publication number
ATE412766T1
ATE412766T1 AT01945643T AT01945643T ATE412766T1 AT E412766 T1 ATE412766 T1 AT E412766T1 AT 01945643 T AT01945643 T AT 01945643T AT 01945643 T AT01945643 T AT 01945643T AT E412766 T1 ATE412766 T1 AT E412766T1
Authority
AT
Austria
Prior art keywords
heart muscle
heart
muscle cells
cells
apoptosis
Prior art date
Application number
AT01945643T
Other languages
English (en)
Inventor
Haruhide Kimura
Nobuyuki Koyama
Seiichi Tanida
Tadamitsu Kishimoto
Keiko Takihara
Hisao Hirota
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Application granted granted Critical
Publication of ATE412766T1 publication Critical patent/ATE412766T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5061—Muscle cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics
    • C12N2503/02—Drug screening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2510/00—Detection of programmed cell death, i.e. apoptosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT01945643T 2000-06-28 2001-06-27 Verfahren zur herstellung von herzmuskelzellen und verfahren zur suche von behandlungen von herzerkrankungen ATE412766T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2000194805 2000-06-28

Publications (1)

Publication Number Publication Date
ATE412766T1 true ATE412766T1 (de) 2008-11-15

Family

ID=18693571

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01945643T ATE412766T1 (de) 2000-06-28 2001-06-27 Verfahren zur herstellung von herzmuskelzellen und verfahren zur suche von behandlungen von herzerkrankungen

Country Status (6)

Country Link
US (2) US20030175847A1 (de)
EP (2) EP2090663A3 (de)
AT (1) ATE412766T1 (de)
AU (1) AU2001267844A1 (de)
DE (1) DE60136358D1 (de)
WO (1) WO2002000850A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4520855B2 (ja) * 2002-09-17 2010-08-11 株式会社 ジャパン・ティッシュ・エンジニアリング 細胞分散装置、細胞分散用カセット及び組織保持部材
US8168718B2 (en) 2005-12-09 2012-05-01 Exxonmobil Chemical Patents Inc. Thermoplastic vulcanizate adhesive compositions
EP2226633A1 (de) * 2009-03-06 2010-09-08 Charité - Universitätsmedizin Berlin Verwendungen und Verfahren zur Identifikation einer zytoprotektiven Verbindung mit gp130 oder LIFRalpha
CN108949673A (zh) * 2018-08-13 2018-12-07 武汉华联科生物技术有限公司 一种大鼠胎鼠心肌细胞原代分离方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3948725A (en) * 1974-05-30 1976-04-06 Godo Shusei Kabushiki Kaisha Neutral protease useful for animal tissue and cell culture
JPH0372872A (ja) * 1988-07-12 1991-03-28 Bio Kagaku Kenkyusho:Kk 無血清培地及びそれを用いた哺乳類細胞の培養法
US5543318A (en) * 1991-06-12 1996-08-06 Smith; David A. Method of isolation, culture and proliferation of human atrial myocytes
US5378698A (en) * 1991-10-21 1995-01-03 Shionogi & Co., Ltd. Benzothiazepine derivatives
US5919449A (en) * 1995-05-30 1999-07-06 Diacrin, Inc. Porcine cardiomyocytes and their use in treatment of insufficient cardiac function
US6133233A (en) * 1997-02-18 2000-10-17 Kansas State University Research Foundation Peptide modulation of reperfusion injury
WO1999011771A1 (en) * 1997-09-04 1999-03-11 Science Research Laboratory, Inc. Cell separation using electric fields
AU748334B2 (en) * 1997-10-16 2002-05-30 Board Of Regents, The University Of Texas System Models and treatments for cardiac hypertrophy in relation with NF-AT3 function

Also Published As

Publication number Publication date
AU2001267844A1 (en) 2002-01-08
DE60136358D1 (de) 2008-12-11
WO2002000850A1 (en) 2002-01-03
EP1295936A1 (de) 2003-03-26
EP1295936A4 (de) 2004-11-10
EP2090663A3 (de) 2009-11-11
US20080160553A1 (en) 2008-07-03
EP1295936B1 (de) 2008-10-29
US20030175847A1 (en) 2003-09-18
EP2090663A2 (de) 2009-08-19

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