ATE413378T1 - Verfahren zur herstellung von phenylethylaminen, insbesondere venlafaxin - Google Patents
Verfahren zur herstellung von phenylethylaminen, insbesondere venlafaxinInfo
- Publication number
- ATE413378T1 ATE413378T1 AT02743616T AT02743616T ATE413378T1 AT E413378 T1 ATE413378 T1 AT E413378T1 AT 02743616 T AT02743616 T AT 02743616T AT 02743616 T AT02743616 T AT 02743616T AT E413378 T1 ATE413378 T1 AT E413378T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- general formula
- carbon atom
- compounds
- precursor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/44—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
- C07C209/48—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN208CH2002 | 2002-03-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE413378T1 true ATE413378T1 (de) | 2008-11-15 |
Family
ID=28053434
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02743616T ATE413378T1 (de) | 2002-03-26 | 2002-06-13 | Verfahren zur herstellung von phenylethylaminen, insbesondere venlafaxin |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7026513B2 (de) |
| EP (1) | EP1490325B1 (de) |
| AT (1) | ATE413378T1 (de) |
| AU (1) | AU2002345346B2 (de) |
| CA (1) | CA2482569C (de) |
| DE (1) | DE60229789D1 (de) |
| NZ (1) | NZ535548A (de) |
| WO (1) | WO2003080560A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10359154A1 (de) * | 2003-12-16 | 2005-07-28 | Krka Tovarna Zdravil, D.D. | Verfahren zur Herstellung von Venlafaxin und Venlafaxinhydrochlorid der Form I |
| EP1721889A1 (de) * | 2005-05-12 | 2006-11-15 | Dishman Pharmaceuticals & Chemicals Ltd. | Verfahren zur Herstellung von Phenethylaminderivaten |
| CA2625832A1 (en) * | 2005-10-19 | 2007-04-26 | Vinod Kumar Kansal | Process for the preparation of highly pure 1-[2-dimethylamino-(4-methoxyphenyl) ethyl]cyclohexanol hydrochloride |
| MX2007016179A (es) * | 2006-04-17 | 2008-03-11 | Teva Pharma | Formas cristalinas de o-desmetilvenlafaxina. |
| US20090069601A1 (en) * | 2006-07-26 | 2009-03-12 | Valerie Niddam-Hildesheim | Processes for the synthesis of O-desmethylvenlafaxine |
| KR101019455B1 (ko) * | 2006-07-26 | 2011-03-07 | 테바 파마슈티컬 인더스트리즈 리미티드 | Ｏ-데스메틸벤라팍신의 합성 방법 |
| US20090137846A1 (en) * | 2006-07-26 | 2009-05-28 | Valerie Niddam-Hildesheim | Processes for the synthesis of O-Desmethylvenlafaxine |
| US20080221356A1 (en) * | 2006-07-26 | 2008-09-11 | Valerie Niddam-Hildesheim | Processes for the synthesis of O-desmethylvenlafaxine |
| US20100210719A1 (en) * | 2007-07-12 | 2010-08-19 | Dr. Reddy's Laboratories Ltd. | O-desmethylvenlafaxine |
| EP2252574A1 (de) * | 2008-03-06 | 2010-11-24 | Teva Pharmaceutical Industries Ltd. | Verfahren zur herstellung von dimer-unreinheitsfreiem o-desmethylvenlafaxin |
| WO2009144517A1 (en) * | 2008-04-14 | 2009-12-03 | Egis Gyógyszergyár Nyilvánosan Müködö | Process for the preparation of cyclohexanol derivatives |
| CA2720538A1 (en) * | 2008-06-16 | 2010-01-21 | Teva Pharmaceutical Industries Ltd. | Solid states of o-desmethylvenlafaxine salts |
| KR101409554B1 (ko) * | 2010-03-29 | 2014-06-19 | 플리바 흐르바츠카 디.오.오. | Ｏ-데스메틸벤라팍신 푸마레이트의 결정형 |
| CN106866434B (zh) * | 2017-02-14 | 2018-10-30 | 齐鲁天和惠世制药有限公司 | 一种盐酸文拉法辛中间体的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2462736A (en) | 1944-08-09 | 1949-02-22 | Du Pont | Preparation of n,n' dimethylethanolamine |
| US4535186A (en) * | 1983-04-19 | 1985-08-13 | American Home Products Corporation | 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives |
| US6350912B1 (en) * | 2001-02-28 | 2002-02-26 | Council Of Scientific And Industrial Research | One pot process for the preparation of 1-[2-dimethylamino-(4-methoxyphenyl)-ethyl]cyclohexanol |
-
2002
- 2002-06-13 WO PCT/IN2002/000131 patent/WO2003080560A1/en not_active Ceased
- 2002-06-13 US US10/508,930 patent/US7026513B2/en not_active Expired - Fee Related
- 2002-06-13 NZ NZ535548A patent/NZ535548A/en unknown
- 2002-06-13 AT AT02743616T patent/ATE413378T1/de not_active IP Right Cessation
- 2002-06-13 EP EP02743616A patent/EP1490325B1/de not_active Expired - Lifetime
- 2002-06-13 AU AU2002345346A patent/AU2002345346B2/en not_active Ceased
- 2002-06-13 CA CA2482569A patent/CA2482569C/en not_active Expired - Fee Related
- 2002-06-13 DE DE60229789T patent/DE60229789D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE60229789D1 (de) | 2008-12-18 |
| EP1490325A1 (de) | 2004-12-29 |
| US7026513B2 (en) | 2006-04-11 |
| CA2482569A1 (en) | 2003-10-02 |
| WO2003080560A1 (en) | 2003-10-02 |
| AU2002345346A1 (en) | 2003-10-08 |
| NZ535548A (en) | 2005-12-23 |
| AU2002345346B2 (en) | 2009-12-03 |
| CA2482569C (en) | 2010-11-09 |
| EP1490325B1 (de) | 2008-11-05 |
| US20050228198A1 (en) | 2005-10-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |