ATE415969T1 - (s)-benzochinolizincarbonsäuren und ihre verwendung als antibakterielle mittel - Google Patents

(s)-benzochinolizincarbonsäuren und ihre verwendung als antibakterielle mittel

Info

Publication number
ATE415969T1
ATE415969T1 AT00939047T AT00939047T ATE415969T1 AT E415969 T1 ATE415969 T1 AT E415969T1 AT 00939047 T AT00939047 T AT 00939047T AT 00939047 T AT00939047 T AT 00939047T AT E415969 T1 ATE415969 T1 AT E415969T1
Authority
AT
Austria
Prior art keywords
benzoquinolicin
carboxylic acids
antibiotic
compounds
antibacterial agents
Prior art date
Application number
AT00939047T
Other languages
English (en)
Inventor
M V Patel
S V Gupte
Y Chugh
D G Saogi
S K Agarwal
Souza N J De
H F Khorakiwala
Original Assignee
Wockhardt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wockhardt Ltd filed Critical Wockhardt Ltd
Application granted granted Critical
Publication of ATE415969T1 publication Critical patent/ATE415969T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT00939047T 1999-05-07 2000-05-08 (s)-benzochinolizincarbonsäuren und ihre verwendung als antibakterielle mittel ATE415969T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN9900016 1999-05-07
US17067699P 1999-12-14 1999-12-14

Publications (1)

Publication Number Publication Date
ATE415969T1 true ATE415969T1 (de) 2008-12-15

Family

ID=26324122

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00939047T ATE415969T1 (de) 1999-05-07 2000-05-08 (s)-benzochinolizincarbonsäuren und ihre verwendung als antibakterielle mittel

Country Status (5)

Country Link
US (3) US7247642B2 (de)
EP (2) EP2030620A1 (de)
AT (1) ATE415969T1 (de)
DE (1) DE60040979D1 (de)
WO (1) WO2000068229A2 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000068229A2 (en) 1999-05-07 2000-11-16 Wockhardt Limited (s)-benzoquinolizine carboxylic acids and their use as antibacterial agents
US6514986B2 (en) * 2000-11-22 2003-02-04 Wockhardt Limited Chiral fluoroquinolone arginine salt forms
AU7866601A (en) * 2000-05-08 2001-11-20 Shiv Kumar Agarwal Chiral fluoroquinolone arginine salt forms
US6608078B2 (en) 2000-05-08 2003-08-19 Wockhardt Limited Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment
US7098219B2 (en) 2000-08-01 2006-08-29 Wockhart Limited Inhibitors of cellular efflux pumps of microbes
US6878713B2 (en) 2001-04-25 2005-04-12 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6964966B2 (en) * 2001-04-25 2005-11-15 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
AU2002361493A1 (en) * 2001-12-13 2003-06-23 Wockhardt Limited New generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
EP1918289A3 (de) 2002-05-28 2009-08-19 Wockhardt Limited Kristalline Form eines Fluorchinolon-Argininsalzes
WO2003099815A1 (en) * 2002-05-28 2003-12-04 Wockhardt Limited Crystalline fluoroquinolone arginine salt form
DE60311486T2 (de) * 2002-08-20 2007-11-08 Lonza Inc. Stabile synergistische antimikrobielle zusammensetzungen aus aldehyddonatoren und deshydroessigsüure mit niedrigem gehalt an freiem formaldehyd
EP1578449A2 (de) * 2002-12-31 2005-09-28 Wockhardt Limited Zusammensetzungen vonbenzochinolizincarbonsäure-antibiotika
AU2003302305A1 (en) * 2002-12-31 2004-07-22 Sachin S Bhagwat Benzoquinolizine-2-carboxylic acid-containing compositions
EP1610759A4 (de) * 2003-04-07 2007-04-25 Cylene Pharmaceuticals Inc Substituierte chinobenzoxazin-analoga
AU2003304460A1 (en) * 2003-09-04 2005-03-29 Wockhardt Limited Benzoquinolizine-2-carboxylic acid arginine salt tetrahydrate
CN101500564B (zh) * 2006-03-07 2012-07-25 沃克哈特有限公司 苯并喹嗪-2-羧酸的前药
WO2008038122A2 (en) * 2006-09-29 2008-04-03 Wockhardt Research Centre Processes for the preparation of 7-substituted 3,3-dimethyl-4-amino-piperidino-quinolone carboxylic acid derivatives
WO2008053295A2 (en) * 2006-10-30 2008-05-08 Wockhardt Research Centre Pharmaceutical compositions of benzoquinolizine-2-carboxylic acid
WO2009027762A2 (en) * 2007-08-24 2009-03-05 Wockhardt Research Centre Liquid dosage forms of fluoroquinolone antibiotics or salt thereof for ophthalmic, otic and nasal administration
WO2009040754A2 (en) * 2007-09-27 2009-04-02 Wockhardt Research Centre Polymorphs of s-(-)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1h,5h-benzo[i,j]quinolizine-2-carboxylic acid lysine salt
CN101513406A (zh) * 2008-02-21 2009-08-26 南京长澳医药科技有限公司 一种稳定的s-(-)-那氟沙星l-精氨酸盐组合物、其制备方法及用途
EP2536408A1 (de) * 2010-02-16 2012-12-26 Wockhardt Research Centre Effluxpumpenhemmer
CN102532131B (zh) * 2010-12-22 2015-09-16 南京长澳医药科技有限公司 一种s-(-)-那氟沙星-l-精氨酸盐的制备方法
MX366887B (es) * 2011-09-28 2019-07-29 Wockhardt Ltd Tetrahidrato de la sal de l-arginina del ácido s-(-)-9-fluoro-6,7-dihidro-8- (4-hidroxipiperidin-1-il) -5-metil-1-oxo-1h, 5h-benzo[i,j] quinolizin-2-carboxílico puro, y un proceso para su preparación.
BR112017016393A2 (pt) * 2015-05-08 2018-03-27 Wockhardt Limited composições farmacêuticas estáveis compreendendo agente antibacteriano
EP3435976B1 (de) * 2017-04-14 2021-03-10 Wockhardt Limited Antibakterielle zusammensetzungen

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2131483A (en) * 1933-06-30 1938-09-27 John A Dienner Ignition coil
US4007266A (en) * 1968-05-03 1977-02-08 Choay S.A. Pharmaceutical composition containing vitamin B12, process of making the same and method of treatment
US3536809A (en) 1969-02-17 1970-10-27 Alza Corp Medication method
US3598123A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3984403A (en) 1972-06-30 1976-10-05 Takeda Chemical Industries, Ltd. Arginine and lysine salts of acid cephalosporins
US3985882A (en) 1972-11-02 1976-10-12 Riker Laboratories, Inc. Substituted benzo[ij]quinolinzine-2-carboxylic acids and derivatives thereof as bactericidal agents
US3924042A (en) 1973-03-26 1975-12-02 Minnesota Mining & Mfg Method for treatment of bacterial plant disease
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4051247A (en) 1975-04-14 1977-09-27 Riker Laboratories, Inc. Method of using 7-hydroxy-benzo[ij]quinolizine-2-carboxylic acid derivatives
US4008719A (en) 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
US4416884A (en) 1978-04-12 1983-11-22 Otsuka Pharmaceutical Co., Ltd. Piperazinylbenzoheterocyclic compounds
US4185337A (en) * 1978-09-26 1980-01-29 Thetford Corporation Portable toilet with improved flush apparatus
US4364929A (en) * 1979-04-02 1982-12-21 The Purdue Frederick Company Germicidal colloidal lubricating gels and method of producing the same
JPS57176987A (en) 1981-04-24 1982-10-30 Otsuka Pharmaceut Co Ltd Pyrrolo(3,2,1-ij)quinoline-5-carboxylic acid derivative
JPS5781486A (en) 1980-11-10 1982-05-21 Otsuka Pharmaceut Co Ltd Benzo(ij)quinolidine-2-carboxylic acid derivative
NO156828C (no) 1980-11-10 1987-12-02 Otsuka Pharma Co Ltd Analogifremgangsm te for fremstilling av antibakterielt virksomme benzoheterocykliske forbindelser.
CH649267A5 (de) * 1980-11-17 1985-05-15 Ferag Ag Verfahren und vorrichtung zum einbringen wenigstens einer einlage in druckprodukte.
US4404207A (en) 1981-11-06 1983-09-13 Riker Laboratories, Inc. Antimicrobial 8-substituted benzo [IJ]quinolizines
JPS5890511A (ja) 1981-11-25 1983-05-30 Otsuka Pharmaceut Co Ltd 抗菌剤
JPS59106488A (ja) 1982-12-10 1984-06-20 Dai Ichi Seiyaku Co Ltd ベンゾキノリジン誘導体
US4443447A (en) 1982-10-25 1984-04-17 Riker Laboratories, Inc. Phenyl-substituted tricyclic antibacterial agents
US4472406A (en) 1982-11-12 1984-09-18 Riker Laboratories, Inc. Antimicrobial 6,7-dihydro-8-(imidazol-1-yl)-5-methyl-1-oxo-1H,5H-benzo [ij]quinolizine-2-carboxylic acids and derivatives
JPS59137482A (ja) 1983-01-26 1984-08-07 Otsuka Pharmaceut Co Ltd ピロロ〔３，２，１，−ｉｊ〕キノリン−５−カルボン酸誘導体
JPS59155381A (ja) 1983-02-22 1984-09-04 Kyorin Pharmaceut Co Ltd ベンゾキノリジンカルボン酸誘導体及びその製造法
US4472407A (en) 1983-03-17 1984-09-18 Riker Laboratories, Inc. Antimicrobial 8-alkoxy-6,7-dihydro-5-methyl-9-fluoro-1-oxo-1H,5H-benzo[ij]qu
US4642355A (en) 1984-02-24 1987-02-10 Otsuka Pharmaceutical Factory, Inc. Proline derivatives
JPH0747535B2 (ja) * 1985-11-26 1995-05-24 日東電工株式会社 消炎鎮痛用貼付剤
JPS63192753A (ja) 1987-02-05 1988-08-10 Otsuka Pharmaceut Co Ltd テトラヒドロキノリン誘導体の光学分割法
JP2688711B2 (ja) 1988-11-10 1997-12-10 大塚製薬株式会社 ベンゾヘテロ環化合物
JP2688712B2 (ja) 1989-01-17 1997-12-10 大塚製薬株式会社 ハロゲン置換キノリン誘導体の製造法
JP2731853B2 (ja) 1989-01-17 1998-03-25 大塚製薬株式会社 トリ低級アルカノイルオキシホウ素の製造法
US5185337A (en) 1989-03-29 1993-02-09 Otsuka Pharmaceutical Co., Ltd. Pyrroloquinoline derivatives and pharmaceutical compositions for antimicrobial use
JPH05339238A (ja) 1992-06-10 1993-12-21 Otsuka Pharmaceut Co Ltd テトラヒドロキノリン誘導体のラセミ化方法
US5424290A (en) * 1992-10-26 1995-06-13 Magainin Pharmaceuticals Inc. Biologically active peptides and uses therefor
TW301607B (de) 1993-03-09 1997-04-01 Takeda Pharm Industry Co Ltd
US6034100A (en) 1993-03-10 2000-03-07 Otsuka Pharmaceutical Co., Ltd. Method for inhibiting cytokine secretion
CA2210007A1 (en) 1995-01-24 1996-08-01 Yasuo Ito Quinoline carboxylic acid
US6121285A (en) 1995-11-22 2000-09-19 Daiichi Pharmaceutical Co., Ltd. Substituted aminocycloalkylpyrrolidine derivatives and cis-substituted aminocycloalkylpyrrolidine derivatives
EP0908181B8 (de) 1996-05-20 2009-04-15 Otsuka Pharmaceutical Co., Ltd. Heilmittel fuer rosazea
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
DE69840599D1 (de) 1997-09-15 2009-04-09 Procter & Gamble Antimikrobielle chinolone, ihre zusammensetzungen und ihre verwendungen
US6229323B1 (en) * 1998-04-23 2001-05-08 Micron Technology, Inc. Automated multi-chip module handler, method of module handling, and module magazine
US6750224B1 (en) * 1999-05-07 2004-06-15 Wockhardt Limited Antibacterial optically pure benzoquinolizine carboxylic acids, processes, compositions and methods of treatment
WO2000068229A2 (en) * 1999-05-07 2000-11-16 Wockhardt Limited (s)-benzoquinolizine carboxylic acids and their use as antibacterial agents
US6514986B2 (en) * 2000-11-22 2003-02-04 Wockhardt Limited Chiral fluoroquinolone arginine salt forms
US6608078B2 (en) 2000-05-08 2003-08-19 Wockhardt Limited Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment
AU2003302305A1 (en) 2002-12-31 2004-07-22 Sachin S Bhagwat Benzoquinolizine-2-carboxylic acid-containing compositions
EP1578449A2 (de) 2002-12-31 2005-09-28 Wockhardt Limited Zusammensetzungen vonbenzochinolizincarbonsäure-antibiotika
AU2003304460A1 (en) 2003-09-04 2005-03-29 Wockhardt Limited Benzoquinolizine-2-carboxylic acid arginine salt tetrahydrate

Also Published As

Publication number Publication date
WO2000068229A2 (en) 2000-11-16
US8507519B2 (en) 2013-08-13
EP2030620A1 (de) 2009-03-04
DE60040979D1 (de) 2009-01-15
US7247642B2 (en) 2007-07-24
EP1175217A2 (de) 2002-01-30
US20080108646A1 (en) 2008-05-08
US20080044466A1 (en) 2008-02-21
US20030207908A1 (en) 2003-11-06
EP1175217B1 (de) 2008-12-03
WO2000068229A3 (en) 2001-03-22
EP2030620A8 (de) 2009-06-24
EP1175217B8 (de) 2009-03-18

Similar Documents

Publication Publication Date Title
ATE415969T1 (de) (s)-benzochinolizincarbonsäuren und ihre verwendung als antibakterielle mittel
ATE309194T1 (de) Neuartige dicarbonsäurederivate mit pharmazeutischen eigenschaften
NO20066041L (no) Anvendelse av substituerte kinolinderivater for behandlingen og legemiddelresistente mykobakterielle sykdommer
NO20071577L (no) Bifenyloksyiddiksyrederivater for behandling av luftveissykdommer
ES2139638T3 (es) 1,4-piperazinas disustituidas para el tratamiento de las enfermedades del sistema nervioso central y de las enfermedades neuroendocrinas.
DE60140491D1 (de) Verwendung einer pharmazeutischen Zusammensetzung mit einem Para-Aminophenylessigsäurederivat für die Behandlung von entzündlichen Erkrankungen des Magen-Darmtrakts
JP2005511642A5 (de)
NO20050309L (no) Nye komplekser av fettsyreestere av polyhydroksyalkan- og pyridinkarboksyderivater
WO2009066041A3 (fr) Derives de 1,2,4,5-tetrahydro-3h-benzazepines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE3750668D1 (de) 7-[3-(Aminomethyl)-3-alkyl-1-pyrrolidinyl]chinolin-3-carbonsäure-Derivate und diese enthaltende pharmazeutische Zusammensetzungen.
DK0453042T3 (da) Hidtil ukendte 2 9-disubstituerede 4H-pyhrido[1 2-a]pyridin-4-oner
NO20001169L (no) 6,9-bro erythromycinderivater
DE60035429D1 (de) Verwendung von sulfodehydroabietinsäure zur behandlung entzündlicher darmerkrankungen
ATE54910T1 (de) Substituierte tetrahydro-3-pyridincarbonsaeuren, ihre ester und amide als cholinergische mittel.
DE69832115T2 (de) Verfahren zum Stabilisieren von Arylcarbonsäuren, dafür verwendbarer Stabilisator und eine stabilisierte Carbonsäure enthaltende wässrige Lösung
CA2494601A1 (en) N-substituted-1h-indol-5-propionic acid compounds as ppar agonists useful for the treatment of diabetes
EA200001029A1 (ru) Производные гигромицина
MXPA01007705A (es) Derivado de benzamida y medicamento que lo contiene.
US20170267632A1 (en) Methionine analogs and methods of using same
MXPA05008711A (es) Uso de r-10-hidroxi-10,11-dihidro-carbamazepina en dolor neuropatico.
DK1209166T3 (da) Hidtil ukendte A-500 359-derivater
MX9303437A (es) Nuevos derivados de quinolina y procesos para su preparacion.
DE60314920D1 (de) Benzochinolizin-2-carbonsäureargininsalz- tetrahydrat
ATE234320T1 (de) Beta,beta-disubstituierte derivate von 9-deoxo-9a-n-ethenyl-9a-aza-9a-homoerythromycin a
FR2835253B1 (fr) Composes, en particulier de derives urees ou esters de l'acide haloacetamidobenzoique et leur utilisation pour le traitement de maladies parasitaires

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties