ATE416186T1 - Phenylethylenamin-derivate - Google Patents
Phenylethylenamin-derivateInfo
- Publication number
- ATE416186T1 ATE416186T1 AT98937826T AT98937826T ATE416186T1 AT E416186 T1 ATE416186 T1 AT E416186T1 AT 98937826 T AT98937826 T AT 98937826T AT 98937826 T AT98937826 T AT 98937826T AT E416186 T1 ATE416186 T1 AT E416186T1
- Authority
- AT
- Austria
- Prior art keywords
- phenylethyleneamine
- derivatives
- alkyl
- amino
- chem
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0819—Tripeptides with the first amino acid being acidic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25587997 | 1997-08-15 | ||
| JP18680298 | 1998-05-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE416186T1 true ATE416186T1 (de) | 2008-12-15 |
Family
ID=26503986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98937826T ATE416186T1 (de) | 1997-08-15 | 1998-08-14 | Phenylethylenamin-derivate |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6255285B1 (de) |
| EP (1) | EP1006122B1 (de) |
| KR (1) | KR20010022924A (de) |
| CN (1) | CN1272114A (de) |
| AT (1) | ATE416186T1 (de) |
| AU (1) | AU741216B2 (de) |
| CA (1) | CA2301687A1 (de) |
| DE (1) | DE69840296D1 (de) |
| TW (1) | TW460478B (de) |
| WO (1) | WO1999009053A1 (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69429895T2 (de) * | 1993-06-28 | 2002-08-29 | American Home Products Corp., Madison | Neue Behandlungsmethoden durch Verwendung von Phenethylderivaten |
| US6329372B1 (en) * | 1998-01-27 | 2001-12-11 | Celltech Therapeutics Limited | Phenylalanine derivatives |
| TW509699B (en) * | 1998-09-24 | 2002-11-11 | Chugau Pharmaceutical Co Ltd | Ethylamine derivatives |
| CN1343219A (zh) * | 1999-01-28 | 2002-04-03 | 中外制药株式会社 | 取代的苯乙基胺衍生物 |
| US6716452B1 (en) | 2000-08-22 | 2004-04-06 | New River Pharmaceuticals Inc. | Active agent delivery systems and methods for protecting and administering active agents |
| US6511980B2 (en) * | 2000-05-05 | 2003-01-28 | Ortho Mcneil Pharmaceutical, Inc. | Substituted diamine derivatives useful as motilin antagonists |
| GB0030304D0 (en) | 2000-12-13 | 2001-01-24 | Lilly Co Eli | Compounds |
| EP1312612A4 (de) * | 2000-08-24 | 2004-09-22 | Chugai Pharmaceutical Co Ltd | Zyklisches peptid-derivat |
| US8394813B2 (en) | 2000-11-14 | 2013-03-12 | Shire Llc | Active agent delivery systems and methods for protecting and administering active agents |
| WO2002057791A2 (en) * | 2000-11-29 | 2002-07-25 | Lifespan Biosciences, Inc. | Diagnostic and therapeutic compositions and methods related to grp 38 |
| WO2002059141A1 (fr) * | 2001-01-25 | 2002-08-01 | Chugai Seiyaku Kabushiki Kaisha | Derives peptidiques |
| WO2003084997A1 (en) * | 2001-04-10 | 2003-10-16 | Transtech Pharma, Inc. | Probes, systems and methods for drug discovery |
| KR100575944B1 (ko) | 2001-06-28 | 2006-05-02 | 화이자 프로덕츠 인코포레이티드 | 미소체 트리글리세라이드 전달 단백질(ｍｔｐ) 및/또는아포지방단백질 ｂ(ａｐｏ ｂ)분비의 억제제로서의트리아미드-치환된 인돌, 벤조푸란 및 벤조티오펜 |
| US20060014697A1 (en) * | 2001-08-22 | 2006-01-19 | Travis Mickle | Pharmaceutical compositions for prevention of overdose or abuse |
| US7338939B2 (en) * | 2003-09-30 | 2008-03-04 | New River Pharmaceuticals Inc. | Abuse-resistant hydrocodone compounds |
| US20070066537A1 (en) * | 2002-02-22 | 2007-03-22 | New River Pharmaceuticals Inc. | Compounds and compositions for prevention of overdose of oxycodone |
| US7169752B2 (en) | 2003-09-30 | 2007-01-30 | New River Pharmaceuticals Inc. | Compounds and compositions for prevention of overdose of oxycodone |
| US7375082B2 (en) * | 2002-02-22 | 2008-05-20 | Shire Llc | Abuse-resistant hydrocodone compounds |
| HRP20040784A2 (en) * | 2002-01-29 | 2005-04-30 | Wyeth | Compositions and methods for modulating connexin hemichannels |
| US7659253B2 (en) * | 2002-02-22 | 2010-02-09 | Shire Llc | Abuse-resistant amphetamine prodrugs |
| KR100822498B1 (ko) * | 2002-02-22 | 2008-04-16 | 샤이어 엘엘씨 | 규제된 물질의 남용을 방지하기 위한 새로운 서방성 약학화합물 |
| US7700561B2 (en) * | 2002-02-22 | 2010-04-20 | Shire Llc | Abuse-resistant amphetamine prodrugs |
| WO2003072735A2 (en) * | 2002-02-22 | 2003-09-04 | New River Pharmaceuticals Inc. | Use of peptide-drug conjugation to reduce inter-subject variability of drug serum levels |
| US7105486B2 (en) * | 2002-02-22 | 2006-09-12 | New River Pharmaceuticals Inc. | Abuse-resistant amphetamine compounds |
| SI1644019T2 (en) * | 2003-05-29 | 2018-04-30 | Shire Llc | Abuse resistant amphetamine compounds |
| DK1633774T3 (da) | 2003-06-18 | 2010-05-25 | Tranzyme Pharma Inc | Makrocykliske motilinreceptorantagonister |
| EA008864B1 (ru) * | 2003-09-30 | 2007-08-31 | Нью Ривер Фармасьютикалз Инк. | Фармацевтические композиции для предотвращения передозировки или неправильного употребления лекарственных средств |
| EP2431380A3 (de) | 2006-09-11 | 2013-07-03 | Tranzyme Pharma, Inc. | Makrozyklischer Antagonist des Motilinrezeptors zur Behandlung von Magen-Darm-Motilitätsstörungen |
| US20080287371A1 (en) * | 2007-05-17 | 2008-11-20 | Tranzyme Pharma Inc. | Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex |
| CA3001065A1 (en) | 2015-10-14 | 2017-04-20 | Xiaoxi WEI | Compositions and methods for reducing ice crystal formation |
| CN112812334B (zh) * | 2021-01-11 | 2022-06-17 | 浙江博菲电气股份有限公司 | 一种新能源电机用阻燃槽楔的制备工艺及阻燃槽楔 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994003483A1 (en) * | 1992-07-30 | 1994-02-17 | Chiron Corporation | Endothelin receptor-binding compounds |
| US5470830A (en) | 1993-08-06 | 1995-11-28 | Ohmeda Pharmaceutical Products Division Inc. | Motilin-like polypeptides that inhibit gastrointestinal motor activity |
| JP3449766B2 (ja) | 1993-11-19 | 2003-09-22 | 中外製薬株式会社 | モチリンアンタゴニスト |
| DK0853484T3 (da) * | 1995-06-07 | 2003-01-20 | Torrey Pines Inst | Hidtil ukendte MU-opioid-receptorligander: agonister og antagonister |
| US5712253A (en) | 1996-06-18 | 1998-01-27 | Abbott Laboratories | Macrocyclic 13-membered ring derivatives of erythromycins A and B |
| US6013633A (en) * | 1997-08-07 | 2000-01-11 | University Of Cincinnati | Compounds for control of appetite, blood pressure, cardiovascular response, libido, and circadian rhythm |
| US5972939A (en) | 1997-10-28 | 1999-10-26 | Ortho-Mcneil Pharmaceutical, Inc. | Cyclopentene derivatives useful as antagonists of the motilin receptor |
| CN1343219A (zh) * | 1999-01-28 | 2002-04-03 | 中外制药株式会社 | 取代的苯乙基胺衍生物 |
-
1998
- 1998-08-11 TW TW087113211A patent/TW460478B/zh not_active IP Right Cessation
- 1998-08-14 AT AT98937826T patent/ATE416186T1/de not_active IP Right Cessation
- 1998-08-14 AU AU86490/98A patent/AU741216B2/en not_active Ceased
- 1998-08-14 CN CN98809657A patent/CN1272114A/zh active Pending
- 1998-08-14 KR KR1020007001529A patent/KR20010022924A/ko not_active Ceased
- 1998-08-14 US US09/485,620 patent/US6255285B1/en not_active Expired - Fee Related
- 1998-08-14 WO PCT/JP1998/003627 patent/WO1999009053A1/ja not_active Ceased
- 1998-08-14 CA CA002301687A patent/CA2301687A1/en not_active Abandoned
- 1998-08-14 DE DE69840296T patent/DE69840296D1/de not_active Expired - Lifetime
- 1998-08-14 EP EP98937826A patent/EP1006122B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999009053A1 (en) | 1999-02-25 |
| DE69840296D1 (de) | 2009-01-15 |
| TW460478B (en) | 2001-10-21 |
| CN1272114A (zh) | 2000-11-01 |
| US6255285B1 (en) | 2001-07-03 |
| AU741216B2 (en) | 2001-11-29 |
| KR20010022924A (ko) | 2001-03-26 |
| EP1006122B1 (de) | 2008-12-03 |
| AU8649098A (en) | 1999-03-08 |
| CA2301687A1 (en) | 1999-02-25 |
| EP1006122A4 (de) | 2004-10-13 |
| EP1006122A1 (de) | 2000-06-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |