ATE417617T1 - Mittel zur steurung der expression von il-12 - Google Patents

Mittel zur steurung der expression von il-12

Info

Publication number: ATE417617T1
Authority: AT; Austria
Prior art keywords: expression; active ingredient; hyaluronan; interleukin; enhancer
Prior art date: 2001-03-15

Application number

AT02705197T

Other languages

English (en)

Inventor

Akira Asari

Hitoshi Kurihara

Original Assignee

Seikagaku Kogyo Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-03-15

Filing date

2002-03-14

Publication date

2009-01-15

2002-03-14 Application filed by Seikagaku Kogyo Co Ltd filed Critical Seikagaku Kogyo Co Ltd

2009-01-15 Application granted granted Critical

2009-01-15 Publication of ATE417617T1 publication Critical patent/ATE417617T1/de

Links

102000013462 Interleukin-12 Human genes 0.000 title abstract 7
108010065805 Interleukin-12 Proteins 0.000 title abstract 7
239000004480 active ingredient Substances 0.000 abstract 4
KIUKXJAPPMFGSW-MNSSHETKSA-N hyaluronan Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)C1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H](C(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-MNSSHETKSA-N 0.000 abstract 4
229940099552 hyaluronan Drugs 0.000 abstract 4
229920002674 hyaluronan Polymers 0.000 abstract 4
229940117681 interleukin-12 Drugs 0.000 abstract 3
239000003795 chemical substances by application Substances 0.000 abstract 2
239000003623 enhancer Substances 0.000 abstract 2
239000003112 inhibitor Substances 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Dermatology (AREA)
Diabetes (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Virology (AREA)
Oncology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Hospice & Palliative Care (AREA)
AIDS & HIV (AREA)
Obesity (AREA)
Hematology (AREA)
Emergency Medicine (AREA)
Ophthalmology & Optometry (AREA)
Transplantation (AREA)
Psychiatry (AREA)
Pulmonology (AREA)
Tropical Medicine & Parasitology (AREA)
Gastroenterology & Hepatology (AREA)

AT02705197T 2001-03-15 2002-03-14 Mittel zur steurung der expression von il-12 ATE417617T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2001074078		2001-03-15
JP2001074077		2001-03-15

Publications (1)

Publication Number	Publication Date
ATE417617T1 true ATE417617T1 (de)	2009-01-15

Family

ID=26611324

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02705197T ATE417617T1 (de)	2001-03-15	2002-03-14	Mittel zur steurung der expression von il-12

Country Status (7)

Country	Link
US (1)	US20040097465A1 (de)
EP (1)	EP1369119B1 (de)
JP (1)	JP4234439B2 (de)
AT (1)	ATE417617T1 (de)
CA (1)	CA2440744C (de)
DE (1)	DE60230388D1 (de)
WO (1)	WO2002074318A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7871984B2 (en) *	2003-04-23	2011-01-18	Yukio Sato	Methylated CpG polynucleotide
HUP0303779A2 (en) *	2003-11-20	2006-02-28	Richter Gedeon Vegyeszet	Pharmaceutical compositions containing hyaluronan complex for the treatment of sclerosis multiplex
JP4889206B2 (ja) *	2004-07-01	2012-03-07	有限会社シーバイオン	Ｉｌ−１２産生誘導活性を有するマクロファージ活性化剤
JP4528898B2 (ja) *	2004-07-26	2010-08-25	独立行政法人科学技術振興機構	ケモカイン受容体ｃｃｒ１０の発現誘導剤
JP4576583B2 (ja) *	2005-03-22	2010-11-10	キユーピー株式会社	ヒアルロン酸またはその塩、およびその製造方法、ならびにこれを含有する化粧料および食品組成物
US20070099867A1 (en) *	2005-05-24	2007-05-03	Glycoscience Laboratories, Inc.	Pharmaceutical agent containing hyaluronan as an active ingredient
NO20064337L (no) *	2005-09-26	2007-03-27	Glycoscience Lab Inc	Farmasoytisk middel inneholdende hyaluronan som en aktiv ingrediens
JP2009091248A (ja) *	2006-01-17	2009-04-30	Toshitsu Kagaku Kenkyusho:Kk	外傷性神経障害および／または運動機能障害の治療薬
JP5289936B2 (ja)	2006-02-24	2013-09-11	キユーピー株式会社	新規な低分子ヒアルロン酸および／またはその塩、ならびにこれを用いた化粧料、医薬組成物および食品組成物
FR2908658B1 (fr) *	2006-11-20	2011-11-11	Centre Nat Rech Scient	Composition pour la prevention et/ou le traitement des maladies associees a la surexpression du tnf et/ou de l'il-12
WO2008068854A1 (ja)	2006-12-05	2008-06-12	Glycoscience Laboratories, Inc.	変形性関節症の治療剤
JP2008266171A (ja) *	2007-04-18	2008-11-06	Q P Corp	自己免疫疾患緩和剤ならびにこれを含有する医薬品および食品
EP2262778B8 (de)	2008-03-07	2020-01-01	Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A.	1-benzyl-3-hydroxymethylindazolderivate und ihre verwendung bei der behandlung von auf der expression von mcp-1, cx3cr1 und p40 basierten erkrankungen
PL2254870T3 (pl)	2008-03-07	2016-07-29	Acraf	Pochodne 1-benzylo-3-hydroksymetyloindazolu i ich zastosowanie w leczeniu chorób opartych na ekspresji MCP-1, CX3CR1
JPWO2009113512A1 (ja) *	2008-03-11	2011-07-21	キユーピー株式会社	Ｓｏｃｓ３発現促進剤、これを含有する医薬品および食品、ならびにｓｏｃｓ３の発現を促進する方法
WO2009113512A1 (ja) *	2008-03-11	2009-09-17	キユーピー株式会社	Ｓｏｃｓ３発現促進剤、これを含有する医薬品および食品、ならびにｓｏｃｓ３の発現を促進する方法
FR2931480B1 (fr) *	2008-05-23	2016-04-01	Centre Nat Rech Scient	Analogues synthetiques de phosphatidyl-myo-inositol mannosides pourvus d'une active inhibitrice de la reponse inflammatoire
US8462765B2 (en) *	2008-08-20	2013-06-11	Qualcomm Incorporated	Method and apparatus to perform ranging operations for wireless stations
ES2665254T3 (es)	2011-07-12	2018-04-25	Holy Stone Healthcare Co., Ltd.	Composiciones que comprenden ácido hialurónico para tratamiento y prevención de enfermedades relacionadas con las mucosas
EP2818172A4 (de) *	2012-02-22	2016-02-17	Hyaluronan Res Inst Inc	Tlr4-mittel, gewebehomöostatikum, hepatozytenwachstumsfaktorinduktor, gewebereparierendes mittel und sirtuininduktor mit hyaluronsäurefragmenten als wirkstoffe davon

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5095037B1 (en) *	1989-12-21	1995-12-19	Nissho Kk	Combined anti-inflammatory agent
JP4010574B2 (ja) *	1994-12-05	2007-11-21	電気化学工業株式会社	皮膚外用剤
EP0873128B1 (de) *	1996-01-11	2004-11-17	Jagotec Ag	Orale verabreichung wirksamer mengen von hyaluronsäure

2002
- 2002-03-14 JP JP2002573025A patent/JP4234439B2/ja not_active Expired - Fee Related
- 2002-03-14 WO PCT/JP2002/002433 patent/WO2002074318A1/ja not_active Ceased
- 2002-03-14 DE DE60230388T patent/DE60230388D1/de not_active Expired - Lifetime
- 2002-03-14 US US10/471,824 patent/US20040097465A1/en not_active Abandoned
- 2002-03-14 CA CA002440744A patent/CA2440744C/en not_active Expired - Fee Related
- 2002-03-14 AT AT02705197T patent/ATE417617T1/de not_active IP Right Cessation
- 2002-03-14 EP EP02705197A patent/EP1369119B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CA2440744C (en)	2009-12-08
EP1369119B1 (de)	2008-12-17
US20040097465A1 (en)	2004-05-20
EP1369119A1 (de)	2003-12-10
CA2440744A1 (en)	2002-09-26
WO2002074318A1 (fr)	2002-09-26
DE60230388D1 (de)	2009-01-29
EP1369119A4 (de)	2004-12-15
JPWO2002074318A1 (ja)	2004-07-08
JP4234439B2 (ja)	2009-03-04

Legal Events

Date	Code	Title	Description
2009-06-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE417617T1 (de)	2009-01-15	Mittel zur steurung der expression von il-12
ITRM990338A0 (it)	1999-05-28	Composizione dietetica o farmaceutica utile per la prevenzione o il trattamento dell'iperossaluria.
BR9908004A (pt)	2001-12-18	Composto, composição e método para prevençãoou supressão de uma infecção viral
WO2003053359A3 (en)	2004-04-15	1,3-bis-(substituted-phenyl)-2-propyn-1-ones and their use to treat disorders
DE60043587D1 (de)	2010-02-04	Mittel für erkrankungen assoziert mit knochensubstanzverlust
DE60235083D1 (de)	2010-03-04	Substituierte tetracyclin-verbindungen zur behandlung von malaria
MY141661A (en)	2010-05-31	17b-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
PT1447399E (pt)	2006-09-29	Derivado de 2-oxo-1-pirrolidina e as suas utilizacoes farmaceuticas
NO950297D0 (no)	1995-01-26	Prolinamidderivater
CY1107992T1 (el)	2013-09-04	Συνθεσεις πολυαμιδο-αμικου οξεος υδατικης βασεως
EP1734041A3 (de)	2007-01-24	Platelet adp rezeptor inhibitoren
DE50004334D1 (de)	2003-12-11	Desodoriende zubereitungen enthaltend wasserlösliche -(1,3)-glucane
ATE363267T1 (de)	2007-06-15	Mittel zur verbesserung der hauttextur
DE69834500D1 (de)	2006-06-14	Xanthinderivative zur behandlung von hirnischämie
DE60035429D1 (de)	2007-08-16	Verwendung von sulfodehydroabietinsäure zur behandlung entzündlicher darmerkrankungen
AU2002358082A1 (en)	2003-06-23	Pharmaceutical compositions for the oral administration of heparin or derivatives thereof
EP0974352A4 (de)	2001-06-06	Stoffe zur hemmung der bildung des pterygiums und seines postoperative wiederauftretens
BR9904075A (pt)	2000-09-19	Cetonas
DK1352658T3 (da)	2010-09-20	Forebyggelse eller lægemiddel mod endometriose
BG106407A (en)	2002-10-31	Treatment of migraine by the administration of alpha-lipoic acid or derivatives thereof
MXPA05014143A (es)	2006-02-24	Derivados de cumarina para el tratamiento de trastornos oftalmicos.
HU0102987D0 (en)	2001-09-28	Pharmaceutical composition for treating parkinson's disease comprising astrocyte function-improving agent as active ingredient
NO20062857L (no)	2006-08-18	Farmasoytisk preparat omfattende et sink-hyaluronatkompleks for behandling av multippel sklerose
WO2004048381A3 (en)	2004-08-05	Pyrazoloazepine compounds as pharmaceutical agents
ATE243219T1 (de)	2003-07-15	9a, 11b-dehydro derivative von 9-oxime-3-keto-6-0-methylerythromycin