ATE41770T1 - Derivate von n-(2-pyrrolidinylmethyl)benzamid, verfahren zu ihrer herstellung, zwischenprodukte und pharmazeutische zubereitung. - Google Patents

Derivate von n-(2-pyrrolidinylmethyl)benzamid, verfahren zu ihrer herstellung, zwischenprodukte und pharmazeutische zubereitung.

Info

Publication number: ATE41770T1
Authority: AT; Austria
Prior art keywords: group; lower alkyl; pyrrolidinylmethyl; nhr; manufacture
Prior art date: 1984-01-31

Application number

AT85850022T

Other languages

English (en)

Inventor

Karl Stefan Bengtsson

Thomas Hoegberg

Lars George Johansson

Paulis Tomas De

Hans Eric Peter Stroem

Marianne Elisabet Widman

Sven Ove Oegren

Original Assignee

Astra Laekemedel Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-01-31

Filing date

1985-01-21

Publication date

1989-04-15

1985-01-21 Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab

1989-04-15 Application granted granted Critical

1989-04-15 Publication of ATE41770T1 publication Critical patent/ATE41770T1/de

Links

238000000034 method Methods 0.000 title abstract 3
239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
239000013067 intermediate product Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
SDSNCRLGLMMTNF-UHFFFAOYSA-N n-(pyrrolidin-2-ylmethyl)benzamide Chemical class C=1C=CC=CC=1C(=O)NCC1CCCN1 SDSNCRLGLMMTNF-UHFFFAOYSA-N 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000002252 acyl group Chemical group 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
125000001246 bromo group Chemical group Br* 0.000 abstract 1
125000001309 chloro group Chemical group Cl* 0.000 abstract 1
125000005117 dialkylcarbamoyl group Chemical group 0.000 abstract 1
125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
125000001153 fluoro group Chemical group F* 0.000 abstract 1
125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
239000002184 metal Substances 0.000 abstract 1
125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
-1 methylenedioxy Chemical group 0.000 abstract 1
230000003287 optical effect Effects 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1
125000004950 trifluoroalkyl group Chemical group 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Neurosurgery (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Psychiatry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT85850022T 1984-01-31 1985-01-21 Derivate von n-(2-pyrrolidinylmethyl)benzamid, verfahren zu ihrer herstellung, zwischenprodukte und pharmazeutische zubereitung. ATE41770T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE8400478A SE8400478D0 (sv)	1984-01-31	1984-01-31	Oxysalicylamido derivatives

Publications (1)

Publication Number	Publication Date
ATE41770T1 true ATE41770T1 (de)	1989-04-15

Family

ID=20354529

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT85850022T ATE41770T1 (de)	1984-01-31	1985-01-21	Derivate von n-(2-pyrrolidinylmethyl)benzamid, verfahren zu ihrer herstellung, zwischenprodukte und pharmazeutische zubereitung.

Country Status (25)

Country	Link
EP (1)	EP0156776B1 (de)
JP (1)	JPH07103097B2 (de)
AT (1)	ATE41770T1 (de)
AU (1)	AU575113B2 (de)
CA (1)	CA1253869A (de)
CY (1)	CY1544A (de)
DD (1)	DD231349A5 (de)
DE (1)	DE3569111D1 (de)
DK (1)	DK38685A (de)
ES (3)	ES8609239A1 (de)
FI (1)	FI83771C (de)
GB (1)	GB2153354B (de)
GR (1)	GR850268B (de)
HK (1)	HK53090A (de)
HU (1)	HU198684B (de)
IE (1)	IE57888B1 (de)
IS (1)	IS1442B6 (de)
MY (1)	MY102377A (de)
NO (1)	NO171363C (de)
NZ (1)	NZ210939A (de)
PH (2)	PH22430A (de)
PT (1)	PT79900B (de)
SE (1)	SE8400478D0 (de)
SG (1)	SG35290G (de)
ZA (1)	ZA85158B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5446147A (en) *	1992-04-03	1995-08-29	Trustees Of The University Of Pennsylvania	Fluorinated and iodinated dopamine agents

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5822110B2 (ja) *	1977-08-08	1983-05-06	塩野義製薬株式会社	ベンズアミド誘導体の合成法
FR2440946A2 (fr) *	1978-01-20	1980-06-06	Ile De France	Nouveaux benzamides heterocycliques substitues, leurs procedes de preparation et leur application comme modificateurs du comportement
SE411118B (sv) *	1978-03-23	1979-12-03	Astra Laekemedel Ab	Ett forfarande for framstellning av 2,6-dialkoxibensamider med terapentiska egenskaper
JPS55130957A (en) *	1979-03-30	1980-10-11	Kyowa Hakko Kogyo Co Ltd	Production of benzamide derivative
SE8101536L (sv) *	1981-03-11	1982-09-12	Astra Laekemedel Ab	Bensamid-derivat
SE8205135D0 (sv) *	1982-09-09	1982-09-09	Astra Laekemedel Ab	Benzamido-derivatives

1984
- 1984-01-31 SE SE8400478A patent/SE8400478D0/xx unknown
1985
- 1985-01-07 ZA ZA85158A patent/ZA85158B/xx unknown
- 1985-01-21 EP EP85850022A patent/EP0156776B1/de not_active Expired
- 1985-01-21 NO NO850244A patent/NO171363C/no unknown
- 1985-01-21 DE DE8585850022T patent/DE3569111D1/de not_active Expired
- 1985-01-21 AT AT85850022T patent/ATE41770T1/de not_active IP Right Cessation
- 1985-01-23 CA CA000472638A patent/CA1253869A/en not_active Expired
- 1985-01-25 AU AU38088/85A patent/AU575113B2/en not_active Ceased
- 1985-01-25 NZ NZ210939A patent/NZ210939A/xx unknown
- 1985-01-28 PH PH31786A patent/PH22430A/en unknown
- 1985-01-28 GB GB08502095A patent/GB2153354B/en not_active Expired
- 1985-01-29 DD DD85272829A patent/DD231349A5/de not_active IP Right Cessation
- 1985-01-29 DK DK38685A patent/DK38685A/da not_active Application Discontinuation
- 1985-01-30 GR GR850268A patent/GR850268B/el unknown
- 1985-01-30 HU HU85343A patent/HU198684B/hu not_active IP Right Cessation
- 1985-01-30 FI FI850398A patent/FI83771C/fi not_active IP Right Cessation
- 1985-01-30 PT PT79900A patent/PT79900B/pt not_active IP Right Cessation
- 1985-01-30 ES ES539955A patent/ES8609239A1/es not_active Expired
- 1985-01-30 IE IE220/85A patent/IE57888B1/en not_active IP Right Cessation
- 1985-01-30 JP JP60014622A patent/JPH07103097B2/ja not_active Expired - Lifetime
- 1985-01-31 IS IS2974A patent/IS1442B6/is unknown
1986
- 1986-01-13 ES ES550826A patent/ES8801199A1/es not_active Expired
- 1986-01-13 ES ES550825A patent/ES8707712A1/es not_active Expired
1987
- 1987-09-29 MY MYPI87002193A patent/MY102377A/en unknown
1988
- 1988-02-29 PH PH36568A patent/PH24046A/en unknown
1990
- 1990-05-18 SG SG352/90A patent/SG35290G/en unknown
- 1990-07-12 HK HK530/90A patent/HK53090A/xx not_active IP Right Cessation
1991
- 1991-03-22 CY CY1544A patent/CY1544A/en unknown

Also Published As

Publication number	Publication date
PH24046A (en)	1990-03-05
NZ210939A (en)	1988-10-28
GB8502095D0 (en)	1985-02-27
ES539955A0 (es)	1986-09-01
JPS60178859A (ja)	1985-09-12
PH22430A (en)	1988-09-12
DK38685D0 (da)	1985-01-29
ES8609239A1 (es)	1986-09-01
IS1442B6 (is)	1990-12-14
MY102377A (en)	1992-06-17
FI850398L (fi)	1985-08-01
AU3808885A (en)	1985-08-08
GB2153354B (en)	1987-10-21
NO171363B (no)	1992-11-23
CA1253869A (en)	1989-05-09
GB2153354A (en)	1985-08-21
PT79900B (en)	1987-02-03
EP0156776B1 (de)	1989-03-29
ES550825A0 (es)	1987-08-16
DE3569111D1 (en)	1989-05-03
FI850398A0 (fi)	1985-01-30
NO171363C (no)	1993-03-03
SE8400478D0 (sv)	1984-01-31
ES8801199A1 (es)	1987-12-16
JPH07103097B2 (ja)	1995-11-08
NO850244L (no)	1985-08-01
CY1544A (en)	1991-03-22
PT79900A (en)	1985-02-01
IS2974A7 (is)	1985-08-01
EP0156776A1 (de)	1985-10-02
IE850220L (en)	1985-07-31
HK53090A (en)	1990-07-20
ES550826A0 (es)	1987-12-16
HUT37750A (en)	1986-02-28
IE57888B1 (en)	1993-05-05
DK38685A (da)	1985-08-01
DD231349A5 (de)	1985-12-24
AU575113B2 (en)	1988-07-21
SG35290G (en)	1990-07-13
HU198684B (en)	1989-11-28
FI83771B (fi)	1991-05-15
GR850268B (de)	1985-05-28
ZA85158B (en)	1985-09-25
FI83771C (fi)	1991-08-26
ES8707712A1 (es)	1987-08-16

Legal Events

Date	Code	Title	Description
1989-08-15	UEP	Publication of translation of european patent specification
1999-10-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
KR900700465A (ko)	1990-08-13	화합물
MX11031A (es)	1993-11-01	Proceso para la preparacion de nuevas 1-fenil-3-naftaleniloxipropanaminas producto obtenido y composicion farmaceutica que lo incluye.
PT74563A (en)	1982-04-01	Process for preparing benzamide derivatives and pharmaceutical compositions containing the same
ATE39482T1 (de)	1989-01-15	N-(1-ethyl-2-pyrrolidinylmethyl)-benzamidderivate, verfahren und zwischenprodukte zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen.
ATE41770T1 (de)	1989-04-15	Derivate von n-(2-pyrrolidinylmethyl)benzamid, verfahren zu ihrer herstellung, zwischenprodukte und pharmazeutische zubereitung.
ES8600242A1 (es)	1985-10-01	Un procedimiento para la preparacion de dihidropiridinas.
ES8503655A1 (es)	1985-03-16	Un procedimiento para preparar nuevas dihidropiridinas.
ATE57913T1 (de)	1990-11-15	Catechinamide, verfahren zu ihrer herstellung, zwischenprodukte und pharmazeutische zubereitung.
TH2763B (th)	1992-02-07	ไดไฮโดรพิริดีนชนิดใหม่