ATE420066T1 - Amidoacetonitrilderivate - Google Patents

Amidoacetonitrilderivate

Info

Publication number
ATE420066T1
ATE420066T1 AT04797665T AT04797665T ATE420066T1 AT E420066 T1 ATE420066 T1 AT E420066T1 AT 04797665 T AT04797665 T AT 04797665T AT 04797665 T AT04797665 T AT 04797665T AT E420066 T1 ATE420066 T1 AT E420066T1
Authority
AT
Austria
Prior art keywords
amidoacetonitril
derivatives
amidoacetonitril derivatives
Prior art date
Application number
AT04797665T
Other languages
English (en)
Inventor
Noelle Gauvry
Thomas Goebel
Pierre Ducray
Francois Pautrat
Ronald Kaminsky
Martin Jung
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE420066T1 publication Critical patent/ATE420066T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
    • C07C255/29—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton containing cyano groups and acylated amino groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/32—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT04797665T 2003-11-06 2004-11-05 Amidoacetonitrilderivate ATE420066T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03025290 2003-11-06
GBGB0402677.9A GB0402677D0 (en) 2003-11-06 2004-02-06 Organic compounds

Publications (1)

Publication Number Publication Date
ATE420066T1 true ATE420066T1 (de) 2009-01-15

Family

ID=34575667

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04797665T ATE420066T1 (de) 2003-11-06 2004-11-05 Amidoacetonitrilderivate

Country Status (22)

Country Link
US (2) US7494956B2 (de)
EP (1) EP1682493B8 (de)
JP (1) JP4319680B2 (de)
KR (1) KR100793462B1 (de)
CN (1) CN100447130C (de)
AR (1) AR046322A1 (de)
AT (1) ATE420066T1 (de)
AU (1) AU2004287611B2 (de)
BR (1) BRPI0416294B1 (de)
CA (1) CA2544741C (de)
DE (1) DE602004018967D1 (de)
DK (1) DK1682493T3 (de)
ES (1) ES2317070T3 (de)
GB (1) GB0402677D0 (de)
MX (1) MXPA06005036A (de)
NZ (1) NZ546830A (de)
PL (1) PL1682493T3 (de)
PT (1) PT1682493E (de)
RU (1) RU2370485C2 (de)
SI (1) SI1682493T1 (de)
TW (1) TWI342875B (de)
WO (1) WO2005044784A1 (de)

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GB0402677D0 (en) * 2003-11-06 2004-03-10 Novartis Ag Organic compounds
CN101768129B (zh) 2004-03-05 2012-05-23 日产化学工业株式会社 异*唑啉取代苯甲酰胺化合物的制备中间体
JP5112074B2 (ja) * 2004-11-09 2013-01-09 ノバルティス アーゲー アミドアセトニトリル化合物のラセミ体からのアミドアセトニトリル化合物の鏡像異性体の調製方法
UA97388C2 (ru) * 2007-02-09 2012-02-10 Пфайзер Лімітед Противопаразитарные агенты
KR20110098012A (ko) * 2007-02-09 2011-08-31 화이자 리미티드 구충제
WO2008102232A1 (en) * 2007-02-21 2008-08-28 Pfizer Limited Benzofuran antiparasitic agents
PL3088384T3 (pl) 2007-05-15 2019-06-28 Merial, Inc. Związki aryloazol-2-ilo-cyjanoetyloaminowe, sposób ich wytwarzania oraz sposób ich stosowania
KR102019659B1 (ko) 2007-06-07 2019-09-10 바이엘 애니멀 헬스 게엠베하 체외기생충의 방제
HUE037127T2 (hu) 2007-06-27 2018-08-28 Du Pont Állati károkozó irtására szolgáló eljárás
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
CA2741186C (en) 2008-10-21 2016-07-19 Merial Limited Thioamide compounds, method of making and method of using thereof
PL3050874T3 (pl) 2008-11-14 2019-07-31 Merial Inc. Wzbogacone enancjomerycznie aryloazol-2-ilocyjanoetyloaminowe związki pasożytobójcze
EP2373162B1 (de) 2008-12-03 2013-08-14 Novartis AG Amidoacetonitrilverbindungen und pestizide zusammensetzung davon
GB0905365D0 (en) * 2009-03-27 2009-05-13 Norbrook Lab Ltd A topical parasiticide composition
US8859003B2 (en) * 2009-06-05 2014-10-14 Intercontinental Great Brands Llc Preparation of an enteric release system
US9968564B2 (en) 2009-06-05 2018-05-15 Intercontinental Great Brands Llc Delivery of functional compounds
US20100310726A1 (en) 2009-06-05 2010-12-09 Kraft Foods Global Brands Llc Novel Preparation of an Enteric Release System
US20100307542A1 (en) * 2009-06-05 2010-12-09 Kraft Foods Global Brands Llc Method of Reducing Surface Oil on Encapsulated Material
EP2314292A1 (de) 2009-10-20 2011-04-27 Novartis AG Endoparasitisch wirkende Zusammensetzungen
UY33282A (es) 2010-03-25 2011-09-30 Novartis Ag Composiciones endoparasiticidas
EP2768497A1 (de) 2011-10-19 2014-08-27 Zoetis LLC Verwendung von aminoacetonitrilderivaten gegen endoparasiten
NZ630807A (en) * 2012-03-23 2016-04-29 Pitney Pharmaceuticals Pty Ltd Kinase inhibitors for the treatment of cancer
US8822689B2 (en) 2012-09-19 2014-09-02 Merial Limited Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
US8859005B2 (en) 2012-12-03 2014-10-14 Intercontinental Great Brands Llc Enteric delivery of functional ingredients suitable for hot comestible applications
CN103030575B (zh) * 2013-01-04 2014-10-01 中国农业大学 一类双氰基酰胺化合物及其合成方法与应用
AR094961A1 (es) 2013-03-15 2015-09-09 Lilly Co Eli 1-hidroxi-benzooxaboroles como agentes antiparasitarios
EP2821412A1 (de) 2013-07-01 2015-01-07 Universität Zürich Organometallische 2-cyano-2-aminobenzoat-propyl-Derivate und deren Verwendung als Anthelmintika
AU2014286221B2 (en) * 2013-07-01 2018-05-31 The University Of Melbourne N-(1-cyano-2-hydroxy-1-methyl-ethyl)-4-(trifluoromethylsulfanyl)benzamide derivatives for use as nematocidal drugs
EP3043791B1 (de) 2013-09-13 2019-04-24 Pitney Pharmaceuticals Pty Limited Mittel gegen krebs mit aminoacetonitrilverbindung als wirkstoff
CN105682464A (zh) * 2013-09-26 2016-06-15 苏黎世大学 用作抗蠕虫药的有机金属n-2-氰基-1-羟丙-2基
CN105683206A (zh) * 2013-09-26 2016-06-15 苏黎世大学 二有机金属2-氨基-3-羟基-2-甲基丙腈衍生物作为抗蠕虫药的用途
CA2923370A1 (en) * 2013-09-26 2015-04-02 Universitat Zurich Organometallic compounds for use as anthelmintics
CA2922575C (en) * 2013-11-01 2022-10-11 Newsouth Innovations Pty Limited Pharmaceutical combinations for the treatment of cancer
EP3883648A1 (de) 2018-11-20 2021-09-29 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylaminoverbindung, zusammensetzungen davon, verfahren zur herstellung und verfahren zur verwendung davon
JP7697690B2 (ja) * 2020-03-04 2025-06-24 国立大学法人山口大学 新規なフルオロアルカン誘導体及びそれらを用いたゲル化剤

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TWI236341B (en) * 2001-06-15 2005-07-21 Novartis Ag Aminoacetonitrile compounds for use in the control of endoparasites
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AR037746A1 (es) * 2001-12-06 2004-12-01 Novartis Ag Compuestos derivados de amidoacetonitrilo, un procedimiento para su preparacion, un procedimiento para la preparacion de compuestos intermediarios, una composicion para combatir parasitos, un procedimiento para combatir dichos parasitos, y el empleo de dichos derivados para la preparacion de una com
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GB0402677D0 (en) * 2003-11-06 2004-03-10 Novartis Ag Organic compounds
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JP5112074B2 (ja) 2004-11-09 2013-01-09 ノバルティス アーゲー アミドアセトニトリル化合物のラセミ体からのアミドアセトニトリル化合物の鏡像異性体の調製方法

Also Published As

Publication number Publication date
US20070072944A1 (en) 2007-03-29
CN1902162A (zh) 2007-01-24
US20090176868A1 (en) 2009-07-09
JP4319680B2 (ja) 2009-08-26
EP1682493B1 (de) 2009-01-07
PT1682493E (pt) 2009-02-12
TW200528024A (en) 2005-09-01
CN100447130C (zh) 2008-12-31
SI1682493T1 (sl) 2009-06-30
KR20060088122A (ko) 2006-08-03
GB0402677D0 (en) 2004-03-10
ES2317070T3 (es) 2009-04-16
BRPI0416294B1 (pt) 2018-06-05
WO2005044784A1 (en) 2005-05-19
TWI342875B (en) 2011-06-01
EP1682493B8 (de) 2009-11-25
KR100793462B1 (ko) 2008-01-14
EP1682493A1 (de) 2006-07-26
RU2006119506A (ru) 2007-12-27
AU2004287611B2 (en) 2008-05-15
JP2007510632A (ja) 2007-04-26
DK1682493T3 (da) 2009-04-20
AU2004287611A1 (en) 2005-05-19
AR046322A1 (es) 2005-11-30
BRPI0416294A (pt) 2007-01-23
DE602004018967D1 (de) 2009-02-26
CA2544741A1 (en) 2005-05-19
CA2544741C (en) 2012-08-07
US7964635B2 (en) 2011-06-21
MXPA06005036A (es) 2006-07-06
PL1682493T3 (pl) 2009-06-30
RU2370485C2 (ru) 2009-10-20
US7494956B2 (en) 2009-02-24
NZ546830A (en) 2009-07-31

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