ATE420108T1 - Verfahren zur herstellung von preparationen aus milchprodukten, welche wachstumsfaktoren (tgf- beta und igf-1), lactoperoxidase und immunglobuline mit niedriger gegenseitiger verunreinigung enthalten - Google Patents

Verfahren zur herstellung von preparationen aus milchprodukten, welche wachstumsfaktoren (tgf- beta und igf-1), lactoperoxidase und immunglobuline mit niedriger gegenseitiger verunreinigung enthalten

Info

Publication number: ATE420108T1
Authority: AT; Austria
Prior art keywords: growth factors; igf; tgf; beta; lactoperoxidase
Prior art date: 2001-07-20

Application number

AT02747753T

Other languages

English (en)

Inventor

Marinus Kivits

Catharina Galama

Andor Hendriks

Original Assignee

Campina Bv

Numico Res B V

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-07-20

Filing date

2002-07-22

Publication date

2009-01-15

2002-07-22 Application filed by Campina Bv, Numico Res B V filed Critical Campina Bv

2009-01-15 Application granted granted Critical

2009-01-15 Publication of ATE420108T1 publication Critical patent/ATE420108T1/de

Links

239000003102 growth factor Substances 0.000 title abstract 3
102000004218 Insulin-Like Growth Factor I Human genes 0.000 title abstract 2
108090000723 Insulin-Like Growth Factor I Proteins 0.000 title abstract 2
ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 title abstract 2
108060003951 Immunoglobulin Proteins 0.000 title 1
108010023244 Lactoperoxidase Proteins 0.000 title 1
102000045576 Lactoperoxidases Human genes 0.000 title 1
235000013365 dairy product Nutrition 0.000 title 1
102000018358 immunoglobulin Human genes 0.000 title 1
229940072221 immunoglobulins Drugs 0.000 title 1
239000012535 impurity Substances 0.000 title 1
229940057428 lactoperoxidase Drugs 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
238000002360 preparation method Methods 0.000 title 1
239000011347 resin Substances 0.000 abstract 3
229920005989 resin Polymers 0.000 abstract 3
239000003446 ligand Substances 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
230000009286 beneficial effect Effects 0.000 abstract 1
125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000002209 hydrophobic effect Effects 0.000 abstract 1
238000004191 hydrophobic interaction chromatography Methods 0.000 abstract 1
229910052588 hydroxylapatite Inorganic materials 0.000 abstract 1
230000003993 interaction Effects 0.000 abstract 1
239000008267 milk Substances 0.000 abstract 1
210000004080 milk Anatomy 0.000 abstract 1
235000013336 milk Nutrition 0.000 abstract 1
XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Biochemistry (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Wood Science & Technology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Biomedical Technology (AREA)
Endocrinology (AREA)
Diabetes (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Food Science & Technology (AREA)
Polymers & Plastics (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)

AT02747753T 2001-07-20 2002-07-22 Verfahren zur herstellung von preparationen aus milchprodukten, welche wachstumsfaktoren (tgf- beta und igf-1), lactoperoxidase und immunglobuline mit niedriger gegenseitiger verunreinigung enthalten ATE420108T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01202794		2001-07-20
EP01202795		2001-07-20

Publications (1)

Publication Number	Publication Date
ATE420108T1 true ATE420108T1 (de)	2009-01-15

Family

ID=26076963

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02747753T ATE420108T1 (de)	2001-07-20	2002-07-22	Verfahren zur herstellung von preparationen aus milchprodukten, welche wachstumsfaktoren (tgf- beta und igf-1), lactoperoxidase und immunglobuline mit niedriger gegenseitiger verunreinigung enthalten

Country Status (10)

Country	Link
US (1)	US20040219225A1 (de)
EP (1)	EP1409538B1 (de)
CN (1)	CN1555384B (de)
AT (1)	ATE420108T1 (de)
AU (1)	AU2002318066B2 (de)
CA (1)	CA2454548A1 (de)
DE (1)	DE60230763D1 (de)
DK (1)	DK1409538T3 (de)
NZ (1)	NZ530704A (de)
WO (1)	WO2003008447A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2827290B1 (fr)	2001-07-13	2004-07-09	Pierre Jouan Biotechnologies Sa	Procede d'obtention d'une fraction proteique enrichie en tgf-beta sous forme activee, fraction proteique et applications therapeutiques
FR2889068B1 (fr) *	2005-07-29	2012-03-02	Cie Laitiere Europeenne	Nouvelles fractions proteiques laitieres et leur utilisation pour la prevention ou le traitement des maladies inflammatoires chroniques
FR2901707B1 (fr)	2006-05-31	2017-09-29	Lab Francais Du Fractionnement	Composition de facteur vii recombinant ou transgenique, chaque molecule de facteur vii possedant deux sites de n-glycosylation a motifs glycanniques definis
FR2910786B1 (fr)	2006-12-29	2017-08-11	Laboratoire Francais Du Fractionnement Et Des Biotechnologies (Lfb)	"procede d'extraction d'une proteine presente dans du lait"
FR2912310B1 (fr)	2007-02-13	2009-08-07	Kasan Sarl	Nouvelles compositions cosmetiques et/ou pharmaceutiques et leurs applications.
WO2008119185A1 (en) *	2007-04-03	2008-10-09	Advitech Inc.	Process for the manufacture of a dairy-based anti-inflammatory composition
EP2725035A1 (de)	2007-10-02	2014-04-30	Avaxia Biologics, Inc.	Antikörpertherapie zur Verwendung im Verdauungstrakt
US8367354B2 (en) *	2008-10-24	2013-02-05	Mead Johnson Nutrition Company	Methods for determining the levels of TGF-β in a composition
US8861162B2 (en) *	2010-03-09	2014-10-14	Honeywell International Inc.	High power solid state power controller (SSPC) solution for primary power distribution applications
US20120213796A1 (en) *	2011-02-22	2012-08-23	Fox Barbara S	Polyclonal antibody compositions
AU2013204858B2 (en) *	2012-10-08	2015-06-25	Saputo Dairy Australia Pty Limited	Improved process for purifying milk proteins and products thereof
AU2013204850B2 (en) *	2012-10-08	2015-06-25	Murray Goulburn Co-Operative Co. Limited	Improved process for purifying milk proteins and products thereof
CN108676784B (zh) *	2018-06-06	2021-04-27	中国农业科学院北京畜牧兽医研究所	一种牛乳中乳过氧化物酶的纯化方法
US11109604B2 (en)	2019-05-09	2021-09-07	Memtec LLC	Dairy processing systems and methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8806893D0 (en) *	1988-03-23	1988-04-27	Unilever Plc	Cosmetic composition
NL1005677C2 (nl) *	1997-03-27	1998-09-29	Campina Melkunie Bv	Werkwijze voor het winnen van groeifactoren, of een samenstelling die één of meer groeifactoren bevat, uit melk of een derivaat daarvan.
GB9708641D0 (en) *	1997-04-29	1997-06-18	Knoll Ag	Enzyme concentrate
DE69925870T2 (de) *	1999-10-06	2005-12-08	Campina B.V.	Verfahren zur bereitstellung von wachstumsfaktozubereitungen (tgf-beta und igf-1) mit niedriger gegenseitiger verunreinigung aus milchprodukten

2002
- 2002-07-22 CN CN028182111A patent/CN1555384B/zh not_active Expired - Fee Related
- 2002-07-22 DE DE60230763T patent/DE60230763D1/de not_active Expired - Fee Related
- 2002-07-22 AT AT02747753T patent/ATE420108T1/de not_active IP Right Cessation
- 2002-07-22 DK DK02747753T patent/DK1409538T3/da active
- 2002-07-22 AU AU2002318066A patent/AU2002318066B2/en not_active Ceased
- 2002-07-22 EP EP02747753A patent/EP1409538B1/de not_active Expired - Lifetime
- 2002-07-22 NZ NZ530704A patent/NZ530704A/en not_active IP Right Cessation
- 2002-07-22 US US10/484,255 patent/US20040219225A1/en not_active Abandoned
- 2002-07-22 CA CA002454548A patent/CA2454548A1/en not_active Abandoned
- 2002-07-22 WO PCT/NL2002/000496 patent/WO2003008447A1/en not_active Ceased

Also Published As

Publication number	Publication date
WO2003008447A8 (en)	2003-03-20
WO2003008447A1 (en)	2003-01-30
CN1555384B (zh)	2010-05-26
DE60230763D1 (de)	2009-02-26
NZ530704A (en)	2005-07-29
DK1409538T3 (da)	2009-04-14
EP1409538A1 (de)	2004-04-21
AU2002318066B2 (en)	2007-10-11
CA2454548A1 (en)	2003-01-30
CN1555384A (zh)	2004-12-15
EP1409538B1 (de)	2009-01-07
US20040219225A1 (en)	2004-11-04

Similar Documents

Publication	Publication Date	Title
ATE420108T1 (de)	2009-01-15	Verfahren zur herstellung von preparationen aus milchprodukten, welche wachstumsfaktoren (tgf- beta und igf-1), lactoperoxidase und immunglobuline mit niedriger gegenseitiger verunreinigung enthalten
ATE277950T1 (de)	2004-10-15	Verfahren zur herstellung von immunoglobulinen zur intravenösen verabreichung und anderen immunoglobulin-produkten
WO1993016099A3 (en)	1993-09-30	Dna sequences encoding novel growth/differentiation factors
ATE193301T1 (de)	2000-06-15	Verfahren zur isolierung von proteinen aus milch
ATE148921T1 (de)	1997-02-15	Aus dem gehirn stammender neurotropher faktor
DE182442T1 (de)	1988-08-11	Rekombinante dns-molekuele und verfahren zur herstellung derselben.
ATE90690T1 (de)	1993-07-15	Menschliche somatomedin-traeger-proteinuntereinheiten und verfahren zu ihrer herstellung.
DE60210304D1 (de)	2006-05-18	Verfahren zur herstellung einer proteinhaltigen fraktion, mit beta-tgf in aktivierter form bereichert, sowie die so erhaltene fraktion und deren therapeutische verwendungen
DE69830315D1 (de)	2005-06-30	Galactosylierte glykoproteine enthaltende zusammensetzungen und verfahren zur deren herstellung
ATE544739T1 (de)	2012-02-15	Verfahren zur rückgewinnung von organischen verbindungen aus diesen enthaltenden wässrigen strömen
DE69428356T2 (de)	2002-04-25	Reinigung von plasmaproteinen
SI2895188T1 (en)	2018-05-31	CORRECTED QUALITY ETHANERCEPT WITH HIGH QUALITY AND EXCELLENT EXPERIENCE
DE69925870D1 (de)	2005-07-21	Verfahren zur bereitstellung von wachstumsfaktozubereitungen (tgf-beta und igf-1) mit niedriger gegenseitiger verunreinigung aus milchprodukten
CA2018511C (en)	2001-07-31	Process for the preparation of purified albumin solutions
EP0764658B1 (de)	2002-01-02	Verfahren zur Gewinnung von Immunglobulinen aus Fraktionen, die bei der Fraktionierung von menschlichem Blutplasma entstehen
ATE116348T1 (de)	1995-01-15	Verfahren zur zubereitung beständiger bitumen- polymermischungen.
ATE421339T1 (de)	2009-02-15	Vereinfachte methode zur entfernung von freiem protein während der herstellung von protein- polysaccharid-konjugaten und impfstoffen unter verwendung von medien mit limitierter durchlässigkeit
DE3330770A1 (de)	1985-03-14	Verfahren zur pasteurisierung von humanplasma
DE3854626D1 (de)	1995-12-07	Verfahren zur Herstellung von Komponenten aus supraleitenden oxidkeramischen Materialien.
DE69300551D1 (de)	1995-11-02	Verfahren zur Herstellung von (3R,4R)-3-Hydroxy-4-Hydroxymethyl-4-Butanolid.
DE3787336D1 (de)	1993-10-14	Verfahren zur Herstellung von Copolyesters, die Anisotropie in geschmolzenem Zustand zeigen.
ATE260228T1 (de)	2004-03-15	Verfahren zur herstellung von 2,6- dimethylnaphthalen
DE3853269D1 (de)	1995-04-13	Temperaturkontrolliertes Verfahren zur Herstellung von als Adjuvans für Detergentien verwendbaren 2'2'-Oxodisuccinten.
DE69222361D1 (de)	1997-10-30	Verfahren zur Isolierung von Proteinen aus Milch und Verfahren zur Behandlung von Milch
DE69016017D1 (de)	1995-02-23	Verfahren zur reinigung von hemin, neues heminderivat und verfahren zur herstellung.

Legal Events

Date	Code	Title	Description
2009-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties