ATE420630T1 - Pulverzubereitungen und verfahren zu ihrer herstellung - Google Patents

Pulverzubereitungen und verfahren zu ihrer herstellung

Info

Publication number
ATE420630T1
ATE420630T1 AT01998330T AT01998330T ATE420630T1 AT E420630 T1 ATE420630 T1 AT E420630T1 AT 01998330 T AT01998330 T AT 01998330T AT 01998330 T AT01998330 T AT 01998330T AT E420630 T1 ATE420630 T1 AT E420630T1
Authority
AT
Austria
Prior art keywords
production
particle diameter
powder preparations
formulation
medicament
Prior art date
Application number
AT01998330T
Other languages
English (en)
Inventor
Satomi Onoue
Kousuke Endo
Kazuhisa Kashimoto
Original Assignee
Itoham Foods Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2001088337A external-priority patent/JP2002284703A/ja
Application filed by Itoham Foods Inc filed Critical Itoham Foods Inc
Priority claimed from JP2001364325A external-priority patent/JP4125512B2/ja
Application granted granted Critical
Publication of ATE420630T1 publication Critical patent/ATE420630T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
AT01998330T 2000-11-29 2001-11-29 Pulverzubereitungen und verfahren zu ihrer herstellung ATE420630T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000362704 2000-11-29
JP2001088337A JP2002284703A (ja) 2001-03-26 2001-03-26 粉末製剤
JP2001364325A JP4125512B2 (ja) 2000-11-29 2001-11-29 粉末製剤及びその製造方法

Publications (1)

Publication Number Publication Date
ATE420630T1 true ATE420630T1 (de) 2009-01-15

Family

ID=27345297

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01998330T ATE420630T1 (de) 2000-11-29 2001-11-29 Pulverzubereitungen und verfahren zu ihrer herstellung

Country Status (9)

Country Link
US (1) US20040109827A1 (de)
EP (1) EP1348428B1 (de)
KR (1) KR100587237B1 (de)
CN (1) CN100400031C (de)
AT (1) ATE420630T1 (de)
AU (2) AU2002218503B2 (de)
CA (1) CA2430318C (de)
DE (1) DE60137452D1 (de)
WO (1) WO2002043703A1 (de)

Families Citing this family (30)

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US20060171899A1 (en) * 1998-12-10 2006-08-03 Akwete Adjei Water-stabilized aerosol formulation system and method of making
WO2003080149A2 (en) 2002-03-20 2003-10-02 Mannkind Corporation Inhalation apparatus
GB0327723D0 (en) 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
CN101098678A (zh) 2004-04-23 2008-01-02 锡德克斯公司 含有磺基烷基醚环糊精的dpi制剂
EP1593376A1 (de) * 2004-05-04 2005-11-09 Warner-Lambert Company LLC Verbesserte Pullulankapseln
PL1786784T3 (pl) 2004-08-20 2011-04-29 Mannkind Corp Kataliza syntezy diketopiperazyn
KR101644250B1 (ko) 2004-08-23 2016-07-29 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
MX2007009656A (es) * 2005-02-10 2007-11-07 Glaxo Group Ltd Proceso para elaborar lactosa utilizando tecnicas de clasificacion previa y formulaciones farmaceuticas formadas de la misma.
CN104324362B (zh) 2005-09-14 2018-04-24 曼金德公司 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法
US7629331B2 (en) 2005-10-26 2009-12-08 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
IN2015DN00888A (de) 2006-02-22 2015-07-10 Mannkind Corp
DE102006053375A1 (de) * 2006-11-10 2008-05-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Mischung von Pulvern
ES2929343T3 (es) 2008-06-13 2022-11-28 Mannkind Corp Inhalador de polvo seco accionado por aspiración para la administración de fármacos
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
KR101628410B1 (ko) 2008-06-20 2016-06-08 맨카인드 코포레이션 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
IL223742A (en) 2010-06-21 2016-06-30 Mannkind Corp A dry powder inhaler and preparation for it
AU2012236150B2 (en) 2011-04-01 2016-03-31 Mannkind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
WO2013039167A1 (ja) 2011-09-14 2013-03-21 塩野義製薬株式会社 吸入用医薬組成物
BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
JP5087182B1 (ja) * 2012-06-13 2012-11-28 クリニプロ株式会社 吸入用パウダーの製造方法
CN104619369B (zh) 2012-07-12 2018-01-30 曼金德公司 干粉药物输送系统和方法
WO2014145720A2 (en) * 2013-03-15 2014-09-18 Antioxidant Superfoods, Inc. Fat emulsion providing taste masking for active health and wellness ingredients
MX375448B (es) * 2013-07-18 2025-03-06 Mannkind Corp Composiciones farmacéuticas en polvo seco estables al calor y métodos.
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
TWI745396B (zh) 2016-07-12 2021-11-11 日商鹽野義製藥股份有限公司 吸入用醫藥組成物
WO2019102310A1 (en) * 2017-11-24 2019-05-31 Alaval (Pty) Ltd Vip formulation for management of inflammatory conditions
CN117652666B (zh) * 2023-12-12 2025-11-25 晨光生物科技集团股份有限公司 一种类胡萝卜素微胶囊及其制备方法和应用

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Publication number Priority date Publication date Assignee Title
GB9100009D0 (en) * 1991-01-02 1991-02-20 Cerestar Holding Bv Erythritol compositions
US5354934A (en) * 1993-02-04 1994-10-11 Amgen Inc. Pulmonary administration of erythropoietin
EP0682526B1 (de) * 1993-02-12 2002-09-04 Avant Immunotherapeutics, Inc. PULMONÄRE VERABREICHUNG DES LÖSLICHEN KOMPLEMENT-RECEPTORS TYP 1 sCR1
AU685784B2 (en) * 1993-02-23 1998-01-29 Genentech Inc. Excipient stabilization of polypeptides treated with organic solvents
TW402506B (en) * 1993-06-24 2000-08-21 Astra Ab Therapeutic preparation for inhalation
ATE416755T1 (de) * 1994-03-07 2008-12-15 Nektar Therapeutics Verfahren und zusammensetzung für die pulmonale darreichung von insulin
JPH08301762A (ja) * 1995-05-12 1996-11-19 Teijin Ltd 肺癌治療剤
JPH08337532A (ja) * 1995-06-14 1996-12-24 Takeda Chem Ind Ltd 医薬組成物
JP3634380B2 (ja) * 1996-02-27 2005-03-30 帝人株式会社 粉末状経鼻投与組成物
US5898028A (en) * 1997-03-20 1999-04-27 Novo Nordisk A/S Method for producing powder formulation comprising an insulin
JP4266399B2 (ja) * 1997-12-04 2009-05-20 帝人株式会社 粉末状吸入用医薬品組成物
JP4691298B2 (ja) * 1999-10-12 2011-06-01 科研製薬株式会社 粉末吸入用製剤及びその製造方法

Also Published As

Publication number Publication date
EP1348428A1 (de) 2003-10-01
AU1850302A (en) 2002-06-11
EP1348428A4 (de) 2005-09-21
CN100400031C (zh) 2008-07-09
KR100587237B1 (ko) 2006-06-07
AU2002218503B2 (en) 2006-09-28
CN1486175A (zh) 2004-03-31
US20040109827A1 (en) 2004-06-10
HK1063286A1 (en) 2004-12-24
KR20030096238A (ko) 2003-12-24
WO2002043703A1 (fr) 2002-06-06
CA2430318C (en) 2009-10-27
CA2430318A1 (en) 2002-06-06
EP1348428B1 (de) 2009-01-14
DE60137452D1 (de) 2009-03-05

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