ATE420951T1 - Schützende epitope von adenylate-zyklase- hämolysin(ac-hly) und ihre verwendung zur behandlung oder verhütung von bordetella- infektionen - Google Patents

Schützende epitope von adenylate-zyklase- hämolysin(ac-hly) und ihre verwendung zur behandlung oder verhütung von bordetella- infektionen

Info

Publication number
ATE420951T1
ATE420951T1 AT96401402T AT96401402T ATE420951T1 AT E420951 T1 ATE420951 T1 AT E420951T1 AT 96401402 T AT96401402 T AT 96401402T AT 96401402 T AT96401402 T AT 96401402T AT E420951 T1 ATE420951 T1 AT E420951T1
Authority
AT
Austria
Prior art keywords
hly
hemolysin
treating
adenylate cyclase
protective epitopes
Prior art date
Application number
AT96401402T
Other languages
English (en)
Inventor
Fotini Betsou
Peter Sebo
Farida Nato
Stephanie Landais
Nicole Guiso
Original Assignee
Pasteur Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Institut filed Critical Pasteur Institut
Application granted granted Critical
Publication of ATE420951T1 publication Critical patent/ATE420951T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/825—Bacteria

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT96401402T 1995-06-30 1996-06-25 Schützende epitope von adenylate-zyklase- hämolysin(ac-hly) und ihre verwendung zur behandlung oder verhütung von bordetella- infektionen ATE420951T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9507945A FR2736064B1 (fr) 1995-06-30 1995-06-30 Epitopes protecteurs de l'adenyl cyclase-hemolysine(ac-hty). leur application au traitement ou a la prevention des infections par bordetella

Publications (1)

Publication Number Publication Date
ATE420951T1 true ATE420951T1 (de) 2009-01-15

Family

ID=9480602

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96401402T ATE420951T1 (de) 1995-06-30 1996-06-25 Schützende epitope von adenylate-zyklase- hämolysin(ac-hly) und ihre verwendung zur behandlung oder verhütung von bordetella- infektionen

Country Status (11)

Country Link
US (3) US6309648B1 (de)
EP (1) EP0787796B9 (de)
JP (1) JP4302784B2 (de)
AT (1) ATE420951T1 (de)
AU (1) AU5625796A (de)
CA (1) CA2180280A1 (de)
DE (1) DE69637812D1 (de)
DK (1) DK0787796T3 (de)
ES (1) ES2320392T3 (de)
FR (1) FR2736064B1 (de)
PT (1) PT787796E (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2646776B1 (fr) * 1989-05-12 1994-06-03 Pasteur Institut Utilisation de preparations vaccinantes a base d'adenyl cyclase ou de bacteries les produisant en tant qu'antigenes protecteurs contre les effets des bordetella
FR2728170A1 (fr) * 1994-12-15 1996-06-21 Pasteur Institut Vaccin de type acellulaire anti-bordetella
US7462472B2 (en) * 2001-11-02 2008-12-09 The University Of Chicago Methods and compositions relating to anthrax pathogenesis
EP1489092A1 (de) * 2003-06-18 2004-12-22 Institut Pasteur Modifizierte Bordetella Adenylatcyclase mit oder ohne CD11b/CD18 Interaktionsdomäne und seine Verwendungen
WO2008088771A2 (en) * 2007-01-12 2008-07-24 Cornell Research Foundation, Inc. Adenylyl cyclases as novel targets for the treatment of infection by eukaryotic pathogens
CN101636157A (zh) * 2007-01-12 2010-01-27 康乃尔研究基金会有限公司 作为抗菌干预的新型靶的腺苷酰环化酶
US20100112009A1 (en) * 2008-11-03 2010-05-06 Institut Pasteur Acellular antibordetella vaccine
US20190071706A1 (en) 2016-04-04 2019-03-07 University Of Virginia Patent Foundation Compositions and methods for preventing and treating disease

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8412207D0 (en) * 1984-05-12 1984-06-20 Wellcome Found Antigenic preparations
FR2590483B1 (fr) 1985-11-22 1988-12-09 Pasteur Institut Antigenes purifies ayant des proprietes vaccinantes contre b. pertussis, moyens notamment adns recombinants pour les produire et compositions de vaccins les contenant
FR2606789B1 (fr) 1986-11-17 1991-05-31 Pasteur Institut Preparations d'adenylate cyclase purifiees, procede d'obtention de ces preparations et leurs applications biologiques
DE3781541T2 (de) 1986-12-23 1993-05-06 Univ Leland Stanford Junior Modifiziertes pertussistoxin.
EP0338170A1 (de) 1988-04-19 1989-10-25 Institut Pasteur Immunschutz gewährendes antigenes Protein gegen pathogene Bakterien
EP0338169B1 (de) 1988-04-19 1996-07-24 Institut Pasteur Verfahren zur Gewinnung von Schutzantigenen gegen Bordetella-Infektionen und toxische Prozesse
FR2638169B1 (fr) * 1988-10-25 1991-01-11 Pasteur Institut Derives d'adenyl cyclase et leurs utilisations biologiques
FR2646776B1 (fr) 1989-05-12 1994-06-03 Pasteur Institut Utilisation de preparations vaccinantes a base d'adenyl cyclase ou de bacteries les produisant en tant qu'antigenes protecteurs contre les effets des bordetella
FR2728170A1 (fr) * 1994-12-15 1996-06-21 Pasteur Institut Vaccin de type acellulaire anti-bordetella

Also Published As

Publication number Publication date
JP4302784B2 (ja) 2009-07-29
FR2736064B1 (fr) 1997-09-05
PT787796E (pt) 2009-04-03
DE69637812D1 (de) 2009-03-05
JPH09187284A (ja) 1997-07-22
DK0787796T3 (da) 2009-04-20
EP0787796B9 (de) 2009-08-05
EP0787796A1 (de) 1997-08-06
EP0787796B1 (de) 2009-01-14
CA2180280A1 (fr) 1996-12-31
AU5625796A (en) 1997-01-23
US20060292161A1 (en) 2006-12-28
US6994854B1 (en) 2006-02-07
FR2736064A1 (fr) 1997-01-03
ES2320392T3 (es) 2009-05-21
US7902349B2 (en) 2011-03-08
US6309648B1 (en) 2001-10-30

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