ATE420952T1 - Methode zur identifizierung von substraten oder inhibitoren von transporterproteinen für verzweigte neutrale aminosäuren - Google Patents

Methode zur identifizierung von substraten oder inhibitoren von transporterproteinen für verzweigte neutrale aminosäuren

Info

Publication number
ATE420952T1
ATE420952T1 AT04717881T AT04717881T ATE420952T1 AT E420952 T1 ATE420952 T1 AT E420952T1 AT 04717881 T AT04717881 T AT 04717881T AT 04717881 T AT04717881 T AT 04717881T AT E420952 T1 ATE420952 T1 AT E420952T1
Authority
AT
Austria
Prior art keywords
amino acid
amino acids
branched
neutral amino
inhibitors
Prior art date
Application number
AT04717881T
Other languages
English (en)
Inventor
Hitoshi Endou
Yoshikatsu Kanai
Original Assignee
Human Cell Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Cell Systems Inc filed Critical Human Cell Systems Inc
Application granted granted Critical
Publication of ATE420952T1 publication Critical patent/ATE420952T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT04717881T 2003-03-07 2004-03-05 Methode zur identifizierung von substraten oder inhibitoren von transporterproteinen für verzweigte neutrale aminosäuren ATE420952T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2003062379 2003-03-07

Publications (1)

Publication Number Publication Date
ATE420952T1 true ATE420952T1 (de) 2009-01-15

Family

ID=32959004

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04717881T ATE420952T1 (de) 2003-03-07 2004-03-05 Methode zur identifizierung von substraten oder inhibitoren von transporterproteinen für verzweigte neutrale aminosäuren

Country Status (8)

Country Link
US (1) US7553642B2 (de)
EP (1) EP1609858B1 (de)
JP (2) JP4660375B2 (de)
KR (1) KR101083385B1 (de)
CN (1) CN100590196C (de)
AT (1) ATE420952T1 (de)
DE (1) DE602004019062D1 (de)
WO (1) WO2004078970A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107200779B (zh) * 2017-07-03 2020-04-03 中国农业大学 稳定过表达LAT3的β细胞株的制备方法及其应用
CN114306601A (zh) * 2020-09-28 2022-04-12 中国科学院上海营养与健康研究所 一种l型氨基酸转运蛋白抑制剂或拮抗剂有效干预糖尿病的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001508407A (ja) * 1996-11-13 2001-06-26 財団法人相模中央化学研究所 膜貫通ドメインを有するヒト蛋白質およびそれをコードするｄｎａ
EP0941320A2 (de) * 1996-11-13 1999-09-15 Sagami Chemical Research Center Menschliche proteine mit transmembranen domaenen und dnas dafuer kodierend
EP1100903A1 (de) 1998-07-24 2001-05-23 THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services Pb 39, ein dysreguliertes gen in prostatakrebs und deren verwendung
US7226731B1 (en) * 1998-07-24 2007-06-05 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services PB 39, a gene dysregulated in prostate cancer, and uses thereof
AU2001231177A1 (en) 2000-01-25 2001-08-07 Hyseq, Inc. Methods and materials relating to hematopoietic cytokine-like polypeptides and polynucleotides
JP2002112780A (ja) * 2000-10-03 2002-04-16 Keio Gijuku ヒト膀胱癌抗原
JP2002223765A (ja) * 2001-01-31 2002-08-13 Keio Gijuku ヒト悪性黒色腫抗原
WO2002098917A2 (en) 2001-02-12 2002-12-12 Curagen Corporation Human proteins and nucleic acids encoding same
WO2003009814A2 (en) * 2001-07-25 2003-02-06 Millennium Pharmaceuticals, Inc. Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of prostate cancer
JP2003125780A (ja) * 2001-10-22 2003-05-07 Mitsubishi Pharma Corp 新規ｇｐｃｒ、それをコードする遺伝子及びそれらの用途

Also Published As

Publication number Publication date
WO2004078970A1 (ja) 2004-09-16
EP1609858A1 (de) 2005-12-28
EP1609858B1 (de) 2009-01-14
KR101083385B1 (ko) 2011-11-14
DE602004019062D1 (de) 2009-03-05
JP2010252796A (ja) 2010-11-11
US7553642B2 (en) 2009-06-30
JP5281039B2 (ja) 2013-09-04
JPWO2004078970A1 (ja) 2006-06-08
EP1609858A4 (de) 2007-11-07
CN1756842A (zh) 2006-04-05
KR20050105273A (ko) 2005-11-03
JP4660375B2 (ja) 2011-03-30
US20060246538A1 (en) 2006-11-02
CN100590196C (zh) 2010-02-17

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