ATE421348T1 - Verfahren und vorrichtung zur trennung von blutbestandteilen - Google Patents
Verfahren und vorrichtung zur trennung von blutbestandteilenInfo
- Publication number
- ATE421348T1 ATE421348T1 AT02789988T AT02789988T ATE421348T1 AT E421348 T1 ATE421348 T1 AT E421348T1 AT 02789988 T AT02789988 T AT 02789988T AT 02789988 T AT02789988 T AT 02789988T AT E421348 T1 ATE421348 T1 AT E421348T1
- Authority
- AT
- Austria
- Prior art keywords
- blood cells
- particles
- red blood
- blood components
- cells
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000012503 blood component Substances 0.000 title 1
- 210000003743 erythrocyte Anatomy 0.000 abstract 4
- 239000002245 particle Substances 0.000 abstract 4
- 210000000265 leukocyte Anatomy 0.000 abstract 3
- 239000012530 fluid Substances 0.000 abstract 2
- 206010039238 Rouleaux formation Diseases 0.000 abstract 1
- 239000010836 blood and blood product Substances 0.000 abstract 1
- 229940125691 blood product Drugs 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000007865 diluting Methods 0.000 abstract 1
- 238000005194 fractionation Methods 0.000 abstract 1
- 238000004062 sedimentation Methods 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3692—Washing or rinsing blood or blood constituents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
- A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
- B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0218—Multiple bag systems for separating or storing blood components with filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0439—White blood cells; Leucocytes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2221/00—Applications of separation devices
- B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
- B04B2005/0471—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with additional elutriation separation of different particles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Ecology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- External Artificial Organs (AREA)
- Centrifugal Separators (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33893801P | 2001-12-05 | 2001-12-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE421348T1 true ATE421348T1 (de) | 2009-02-15 |
Family
ID=23326775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02789988T ATE421348T1 (de) | 2001-12-05 | 2002-12-04 | Verfahren und vorrichtung zur trennung von blutbestandteilen |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US7201848B2 (de) |
| EP (1) | EP1454135B1 (de) |
| JP (1) | JP4512367B2 (de) |
| AT (1) | ATE421348T1 (de) |
| AU (1) | AU2002353022A1 (de) |
| CA (1) | CA2455964A1 (de) |
| DE (1) | DE60230997D1 (de) |
| WO (1) | WO2003050536A2 (de) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6579219B2 (en) * | 2001-04-09 | 2003-06-17 | Medtronic, Inc. | Centrifuge bag and methods of use |
| US6890291B2 (en) * | 2001-06-25 | 2005-05-10 | Mission Medical, Inc. | Integrated automatic blood collection and processing unit |
| WO2003050536A2 (en) * | 2001-12-05 | 2003-06-19 | Gambro, Inc. | Methods and apparatus for separation of blood components |
| US7479123B2 (en) | 2002-03-04 | 2009-01-20 | Therakos, Inc. | Method for collecting a desired blood component and performing a photopheresis treatment |
| US7211037B2 (en) | 2002-03-04 | 2007-05-01 | Therakos, Inc. | Apparatus for the continuous separation of biological fluids into components and method of using same |
| US9144583B2 (en) | 2002-03-29 | 2015-09-29 | Tissue Genesis, Inc. | Cell separation apparatus and methods of use |
| US6811777B2 (en) * | 2002-04-13 | 2004-11-02 | Allan Mishra | Compositions and minimally invasive methods for treating incomplete connective tissue repair |
| US7608258B2 (en) * | 2002-04-13 | 2009-10-27 | Allan Mishra | Method for treatment of tendinosis using platelet rich plasma |
| US7037428B1 (en) * | 2002-04-19 | 2006-05-02 | Mission Medical, Inc. | Integrated automatic blood processing unit |
| US20070110737A1 (en) * | 2003-12-29 | 2007-05-17 | Allan Mishra | Compositions and method for decreasing the appearance of skin wrinkles |
| WO2005065242A2 (en) * | 2003-12-29 | 2005-07-21 | Am Biosolutions | Method of treating cancer using platelet releasate |
| US20070122906A1 (en) * | 2003-12-29 | 2007-05-31 | Allan Mishra | Method of culturing cells |
| US7462268B2 (en) * | 2004-08-20 | 2008-12-09 | Allan Mishra | Particle/cell separation device and compositions |
| WO2006027565A1 (en) * | 2004-09-09 | 2006-03-16 | Lifeforce Group Plc | Apheresis tubing set |
| US7476209B2 (en) | 2004-12-21 | 2009-01-13 | Therakos, Inc. | Method and apparatus for collecting a blood component and performing a photopheresis treatment |
| DE102005051645B4 (de) * | 2005-10-26 | 2018-10-18 | Rapid Sampling Technologies Ag | Einrichtung zur Fraktionierung von mit Partikeln beladenen Flüssigkeiten |
| US7386815B2 (en) * | 2005-10-27 | 2008-06-10 | International Business Machines Corporation | Test yield estimate for semiconductor products created from a library |
| WO2008021623A1 (en) * | 2006-08-10 | 2008-02-21 | Gambro Bct, Inc. | Method and apparatus for recirculating elutriation fluids |
| US11174458B2 (en) | 2007-04-23 | 2021-11-16 | Koligo Therapeutics, Inc. | Cell separation apparatus and methods of use |
| US7857744B2 (en) * | 2007-06-19 | 2010-12-28 | Caridianbct, Inc. | Blood processing apparatus with flared cell capture chamber and method |
| US7963901B2 (en) * | 2008-09-12 | 2011-06-21 | Caridianbct, Inc. | Blood processing apparatus with cell capture chamber with protruding inlet |
| US20100112081A1 (en) | 2008-10-07 | 2010-05-06 | Bioparadox, Llc | Use of platelet rich plasma composition in the treatment of cardiac conduction abnormalities |
| EP2337617A4 (de) * | 2008-10-09 | 2013-06-12 | Bioparadox Llc | Plättchenreiche plasmaformulierungen für herzbehandlungen |
| US20100233282A1 (en) * | 2009-03-13 | 2010-09-16 | Allan Mishra | Device and methods for delivery of bioactive materials to the right side of the heart |
| EP2485846B1 (de) | 2009-10-06 | 2019-07-17 | Sartorius Stedim North America Inc. | Verfahren, systeme und vorrichtung zur manipulation von partikeln |
| WO2011069117A1 (en) * | 2009-12-04 | 2011-06-09 | Neostem, Inc. | Method of isolation of stem cell populations from peripheral blood using sized-based separation (elutriation) |
| EP2717942B1 (de) * | 2011-06-13 | 2016-05-18 | Terumo BCT, Inc. | System zur bluttrennung mit einem schwerkraftventil zur steuerung einer trennkammer mit seitengewindebohrung |
| EP2590697B1 (de) | 2011-06-13 | 2015-03-04 | Terumo BCT, Inc. | System zur bluttrennung mit trennkammern mit seitengewindebohrung |
| US9173990B2 (en) | 2011-08-12 | 2015-11-03 | Terumo Bct, Inc. | System for blood separation with replacement fluid apparatus and method |
| US9327296B2 (en) | 2012-01-27 | 2016-05-03 | Fenwal, Inc. | Fluid separation chambers for fluid processing systems |
| EP2836245B1 (de) * | 2012-04-12 | 2018-06-06 | President and Fellows of Harvard College | Verfahren zur isolierung von leukozyten |
| US8803090B2 (en) | 2012-11-09 | 2014-08-12 | Fenwal, Inc. | Citrate detector for blood processing system |
| CN105142689B (zh) | 2013-02-18 | 2017-05-24 | 泰尔茂比司特公司 | 分离复合液体 |
| US9248446B2 (en) | 2013-02-18 | 2016-02-02 | Terumo Bct, Inc. | System for blood separation with a separation chamber having an internal gravity valve |
| GB201306810D0 (en) | 2013-04-15 | 2013-05-29 | Cells4Life Group Llp | Methods of cell separation |
| US20140356893A1 (en) | 2013-06-04 | 2014-12-04 | Allan Mishra | Compositions and methods for using platelet-rich plasma for drug discovery, cell nuclear reprogramming, proliferation or differentiation |
| US10618060B2 (en) | 2013-12-20 | 2020-04-14 | Terumo Bct, Inc. | Centrifuge safety mechanism |
| GB2525202A (en) * | 2014-04-15 | 2015-10-21 | Cells4Life Group Llp | Methods of cell separation |
| RU2708206C2 (ru) | 2014-08-14 | 2019-12-04 | ТЕРУМО БиСиТи, ИНК. | Обработка частиц |
| EP3124063B1 (de) | 2015-07-29 | 2019-04-10 | Fenwal, Inc. | Bluttrennkammer mit fünf anschlüssen und verfahren zur verwendung davon |
| US10099228B2 (en) * | 2015-10-09 | 2018-10-16 | Invetech, Inc. | Apparatus for performing counter flow centrifugation and method of using same |
| ITUB20154668A1 (it) * | 2015-10-14 | 2017-04-14 | Mario Goisis | Dispositivo per la filtrazione del grasso estratto con procedure chirurgiche di liposuzione |
| EP3386561B1 (de) | 2015-12-11 | 2023-05-03 | NxStage Medical, Inc. | Fluidleitungsanschlussvorrichtungen, -verfahren und -systeme |
| WO2018071862A1 (en) * | 2016-10-13 | 2018-04-19 | Terumo Bct, Inc. | Collecting components of a fluid |
| KR101844188B1 (ko) | 2017-04-06 | 2018-03-30 | 재단법인대구경북과학기술원 | 미세 유동 장치 |
| US11964286B2 (en) | 2019-04-12 | 2024-04-23 | Terumo Bct, Inc. | Cell washing chamber for blood processing centrifuge |
| CN110813557A (zh) * | 2019-11-25 | 2020-02-21 | 安徽科门生物科技有限公司 | 一种细胞离心机 |
| EP4146787A4 (de) | 2020-05-08 | 2024-06-26 | Gallant Pet, Inc. | Regenerative zellzusammensetzungen aus der gebärmutter und verwendungen davon |
| EP3936600A1 (de) * | 2020-07-06 | 2022-01-12 | Sartorius Stedim Biotech GmbH | Automatisierte zentrifugeneinstellung einer bioverarbeitungsanlage |
| EP4070826A3 (de) | 2021-04-05 | 2022-11-30 | Fenwal, Inc. | Zentrifugationskammern mit kontinuierlichem fluss |
| AU2023398812A1 (en) * | 2022-12-16 | 2025-07-03 | Flaskworks, Llc | Method for collecting cell types |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2616619A (en) | 1948-08-30 | 1952-11-04 | Norman A Macleod | Method and apparatus for centrifugal elutriation |
| US3825175A (en) | 1973-06-06 | 1974-07-23 | Atomic Energy Commission | Centrifugal particle elutriator and method of use |
| JPS50107565A (de) | 1974-01-29 | 1975-08-25 | ||
| US3967961A (en) * | 1974-12-04 | 1976-07-06 | Xerox Corporation | Photoelectrophoretic imaging process employing a dark charge injecting agent - alkyd resin coating |
| DE2545284A1 (de) | 1975-10-09 | 1977-04-21 | Heraeus Christ Gmbh | Zentrifuge zum waschen biologischen materials in suspension |
| DE2658926A1 (de) | 1976-12-24 | 1978-06-29 | Heraeus Christ Gmbh | Zentrifuge zum waschen von blut |
| US4091989A (en) | 1977-01-04 | 1978-05-30 | Schlutz Charles A | Continuous flow fractionation and separation device and method |
| US4111199A (en) | 1977-03-31 | 1978-09-05 | Isaac Djerassi | Method of collecting transfusable granulocytes by gravity leukopheresis |
| US4146172A (en) | 1977-10-18 | 1979-03-27 | Baxter Travenol Laboratories, Inc. | Centrifugal liquid processing system |
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| US4269718A (en) | 1980-05-05 | 1981-05-26 | The Institutes Of Medical Sciences | Process and device for centrifugal separation of platelets |
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| JPH11335289A (ja) * | 1998-05-27 | 1999-12-07 | Asahi Medical Co Ltd | 血小板除去方法及び細胞組成物 |
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| HK1041454B (en) * | 1998-12-24 | 2004-12-31 | 生物安全股份有限公司 | Blood separation system particularly for concentrating hematopoietic stem cells |
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| AU782391B2 (en) | 1999-04-20 | 2005-07-21 | Richard Leslie Edelson | Differentiation of monocytes into functional dendritic cells |
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| AU2001284695A1 (en) * | 2000-07-31 | 2002-02-13 | New York Medical College | Methods and compositions for the repair and/or regeneration of damaged myocardium |
| WO2003050536A2 (en) * | 2001-12-05 | 2003-06-19 | Gambro, Inc. | Methods and apparatus for separation of blood components |
-
2002
- 2002-12-04 WO PCT/US2002/038566 patent/WO2003050536A2/en not_active Ceased
- 2002-12-04 EP EP02789988A patent/EP1454135B1/de not_active Expired - Lifetime
- 2002-12-04 CA CA002455964A patent/CA2455964A1/en not_active Abandoned
- 2002-12-04 JP JP2003551538A patent/JP4512367B2/ja not_active Expired - Fee Related
- 2002-12-04 DE DE60230997T patent/DE60230997D1/de not_active Expired - Lifetime
- 2002-12-04 US US10/310,528 patent/US7201848B2/en not_active Expired - Lifetime
- 2002-12-04 AU AU2002353022A patent/AU2002353022A1/en not_active Abandoned
- 2002-12-04 AT AT02789988T patent/ATE421348T1/de not_active IP Right Cessation
-
2005
- 2005-05-16 US US11/131,063 patent/US20050250204A1/en not_active Abandoned
-
2007
- 2007-02-28 US US11/680,506 patent/US7588692B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003050536A3 (en) | 2003-09-25 |
| WO2003050536A2 (en) | 2003-06-19 |
| JP2005512089A (ja) | 2005-04-28 |
| AU2002353022A8 (en) | 2003-06-23 |
| US20050250204A1 (en) | 2005-11-10 |
| EP1454135B1 (de) | 2009-01-21 |
| US7201848B2 (en) | 2007-04-10 |
| DE60230997D1 (de) | 2009-03-12 |
| US20070144978A1 (en) | 2007-06-28 |
| EP1454135A2 (de) | 2004-09-08 |
| US20030116512A1 (en) | 2003-06-26 |
| AU2002353022A1 (en) | 2003-06-23 |
| JP4512367B2 (ja) | 2010-07-28 |
| CA2455964A1 (en) | 2003-06-19 |
| US7588692B2 (en) | 2009-09-15 |
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