ATE421522T1 - 6-200 cholansäure(derivat)-einheiten enthaltende sulfatierte molekulare schirme als anti-hiv- und anti-hsv-mittel - Google Patents

6-200 cholansäure(derivat)-einheiten enthaltende sulfatierte molekulare schirme als anti-hiv- und anti-hsv-mittel

Info

Publication number: ATE421522T1
Authority: AT; Austria
Prior art keywords: sup; hiv; derivative; units; cholanic acid
Prior art date: 2004-09-21

Application number

AT05800868T

Other languages

English (en)

Inventor

Steven Regen

Betsy Herold

Original Assignee

Univ Lehigh

Sinai School Medicine

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-09-21

Filing date

2005-09-20

Publication date

2009-02-15

2005-09-20 Application filed by Univ Lehigh, Sinai School Medicine filed Critical Univ Lehigh

2009-02-15 Application granted granted Critical

2009-02-15 Publication of ATE421522T1 publication Critical patent/ATE421522T1/de

Links

239000003795 chemical substances by application Substances 0.000 title abstract 2
230000036436 anti-hiv Effects 0.000 title 1
230000003622 anti-hsv Effects 0.000 title 1
RPKLZQLYODPWTM-KBMWBBLPSA-N cholanoic acid Chemical compound C1CC2CCCC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@@H](CCC(O)=O)C)[C@@]1(C)CC2 RPKLZQLYODPWTM-KBMWBBLPSA-N 0.000 title 1
241000725303 Human immunodeficiency virus Species 0.000 abstract 2
229910052784 alkaline earth metal Inorganic materials 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
208000009889 Herpes Simplex Diseases 0.000 abstract 1
241000700584 Simplexvirus Species 0.000 abstract 1
XSTXAVWGXDQKEL-UHFFFAOYSA-N Trichloroethylene Chemical compound ClC=C(Cl)Cl XSTXAVWGXDQKEL-UHFFFAOYSA-N 0.000 abstract 1
239000003513 alkali Substances 0.000 abstract 1
150000001342 alkaline earth metals Chemical class 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
230000003602 anti-herpes Effects 0.000 abstract 1
150000001768 cations Chemical class 0.000 abstract 1
239000003763 cholanic acid derivative Substances 0.000 abstract 1
150000001830 cholanoic acids Chemical class 0.000 abstract 1
150000001838 cholestanes Chemical class 0.000 abstract 1
150000002009 diols Chemical class 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1
125000001453 quaternary ammonium group Chemical group 0.000 abstract 1
241000894007 species Species 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
IIACRCGMVDHOTQ-UHFFFAOYSA-N sulfamic acid Chemical compound NS(O)(=O)=O IIACRCGMVDHOTQ-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
- C07J41/0061—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives one of the carbon atoms being part of an amide group

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT05800868T 2004-09-21 2005-09-20 6-200 cholansäure(derivat)-einheiten enthaltende sulfatierte molekulare schirme als anti-hiv- und anti-hsv-mittel ATE421522T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US61130604P	2004-09-21	2004-09-21

Publications (1)

Publication Number	Publication Date
ATE421522T1 true ATE421522T1 (de)	2009-02-15

Family

ID=35811741

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT05800868T ATE421522T1 (de)	2004-09-21	2005-09-20	6-200 cholansäure(derivat)-einheiten enthaltende sulfatierte molekulare schirme als anti-hiv- und anti-hsv-mittel

Country Status (5)

Country	Link
US (1)	US20070232576A1 (de)
EP (1)	EP1817325B1 (de)
AT (1)	ATE421522T1 (de)
DE (1)	DE602005012538D1 (de)
WO (1)	WO2006034369A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7960439B1 (en)	2006-06-12	2011-06-14	Iowa State University Research Foundation, Inc.	Environmentally sensitive foldable oligomers

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AUPM623994A0 (en) *	1994-06-15	1994-07-07	Biomolecular Research Institute Limited	Antiviral dendrimers
US5583239A (en) *	1995-05-30	1996-12-10	Lehigh University	Antimicrobial sterol conjugates

2005
- 2005-09-20 US US11/230,806 patent/US20070232576A1/en not_active Abandoned
- 2005-09-20 WO PCT/US2005/033880 patent/WO2006034369A2/en not_active Ceased
- 2005-09-20 AT AT05800868T patent/ATE421522T1/de not_active IP Right Cessation
- 2005-09-20 EP EP05800868A patent/EP1817325B1/de not_active Expired - Lifetime
- 2005-09-20 DE DE602005012538T patent/DE602005012538D1/de not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP1817325B1 (de)	2009-01-21
WO2006034369A2 (en)	2006-03-30
DE602005012538D1 (de)	2009-03-12
US20070232576A1 (en)	2007-10-04
WO2006034369A3 (en)	2006-06-01
EP1817325A2 (de)	2007-08-15

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Legal Events

Date	Code	Title	Description
2009-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties