ATE42306T1 - 21-substituierte thiosteroide. - Google Patents

21-substituierte thiosteroide.

Info

Publication number: ATE42306T1
Authority: AT; Austria
Prior art keywords: sup; group; carbon atoms; substituted; thiosteroids
Prior art date: 1985-06-26

Application number

AT86108656T

Other languages

English (en)

Inventor

Morihiro Mitsukuchi

Tomoyuki Ikemoto

Yoshiaki Watanabe

Kaoru Sota

Original Assignee

Jouveinal Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-06-26

Filing date

1986-06-25

Publication date

1989-05-15

1986-06-25 Application filed by Jouveinal Sa filed Critical Jouveinal Sa

1989-05-15 Application granted granted Critical

1989-05-15 Publication of ATE42306T1 publication Critical patent/ATE42306T1/de

Links

125000004432 carbon atom Chemical group C* 0.000 abstract 3
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000002252 acyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
239000002260 anti-inflammatory agent Substances 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Compounds Of Unknown Constitution (AREA)
Dowels (AREA)
Mechanical Treatment Of Semiconductor (AREA)
Saccharide Compounds (AREA)

AT86108656T 1985-06-26 1986-06-25 21-substituierte thiosteroide. ATE42306T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP13927685		1985-06-26
EP86108656A EP0208202B1 (de)	1985-06-26	1986-06-25	21-Substituierte Thiosteroide

Publications (1)

Publication Number	Publication Date
ATE42306T1 true ATE42306T1 (de)	1989-05-15

Family

ID=15241512

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT86108656T ATE42306T1 (de)	1985-06-26	1986-06-25	21-substituierte thiosteroide.

Country Status (6)

Country	Link
US (1)	US4861765A (de)
EP (1)	EP0208202B1 (de)
JP (1)	JPH0699468B2 (de)
AT (1)	ATE42306T1 (de)
DE (1)	DE3662896D1 (de)
ES (1)	ES8707256A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5439901A (en) *	1993-07-23	1995-08-08	The Procter & Gamble Company	Cyproterone thiopivalate
US5344651A (en) *	1993-07-23	1994-09-06	The Procter & Gamble Company	Cyproterone acetate thioacetate
US5420120A (en) *	1993-12-17	1995-05-30	Alcon Laboratories, Inc.	Anti-inflammatory glucocorticoid compounds for topical ophthalmic use
US6372712B1 (en)	1998-05-22	2002-04-16	The Board Of Trustees Of The Leland Stanford Jr. University	Synthetic bifunctional molecules containing a drug moiety and presenter protein ligand
US6777400B2 (en) *	2000-08-05	2004-08-17	Smithkline Beecham Corporation	Anti-inflammatory androstane derivative compositions
CA2417826A1 (en) *	2000-08-05	2002-02-14	Glaxo Group Limited	17.beta.-carbothioate 17.alpha.-arylcarbonyloxyloxy androstane derivative as anti-inflammatory agents
GB0019172D0 (en) *	2000-08-05	2000-09-27	Glaxo Group Ltd	Novel compounds
US6777399B2 (en)	2000-08-05	2004-08-17	Smithkline Beecham Corporation	Anti-inflammatory androstane derivative compositions
US6858596B2 (en) *	2000-08-05	2005-02-22	Smithkline Beecham Corporation	Formulation containing anti-inflammatory androstane derivative
US6759398B2 (en)	2000-08-05	2004-07-06	Smithkline Beecham Corporation	Anti-inflammatory androstane derivative
US6787532B2 (en) *	2000-08-05	2004-09-07	Smithkline Beecham Corporation	Formulation containing anti-inflammatory androstane derivatives
US6750210B2 (en) *	2000-08-05	2004-06-15	Smithkline Beecham Corporation	Formulation containing novel anti-inflammatory androstane derivative
US6858593B2 (en) *	2000-08-05	2005-02-22	Smithkline Beecham Corporation	Anti-inflammatory androstane derivative compositions
UA77656C2 (en)	2001-04-07	2007-01-15	Glaxo Group Ltd	S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
AR033290A1 (es) *	2001-04-30	2003-12-10	Glaxo Group Ltd	Derivados antiinflamatorios de androstano
US20050175545A1 (en) *	2002-02-04	2005-08-11	Keith Biggadike	Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) *	2002-02-05	2002-03-20	Glaxo Wellcome Mfg Pte Ltd	Formulation containing novel anti-inflammatory androstane derivative
GB2389530B (en) *	2002-06-14	2007-01-10	Cipla Ltd	Pharmaceutical compositions
AU2004207482B2 (en)	2003-01-21	2009-10-08	Merck Sharp & Dohme Corp.	17-carbamoyloxy cortisol derivatives as selective glucocorticoid receptor modulators
US7435757B2 (en) *	2004-07-02	2008-10-14	Schering Ag	2-substituted D-homo-estra-1,3,5(10)-trienes as inhibitors of 17β-hydroxy steroid dehydrogenase type 1
GB0507165D0 (en) *	2005-04-08	2005-05-18	Glaxo Group Ltd	Novel crystalline pharmaceutical product
EP2671508B1 (de)	2005-04-28	2020-09-16	Proteus Digital Health, Inc.	Pharma-Informatiksystem
US9062126B2 (en)	2005-09-16	2015-06-23	Raptor Pharmaceuticals Inc.	Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
GB0615108D0 (en) *	2006-07-28	2006-09-06	Glaxo Group Ltd	Novel formulations
CN101970452A (zh) *	2007-12-21	2011-02-09	先灵公司	C20-c21取代的糖皮质激素受体激动剂
US20110262368A1 (en) *	2007-12-21	2011-10-27	Schering Corporation	C21 thioethers as glucocorticoid receptor agonists
ES2919563T3 (es)	2009-02-20	2022-07-27	Enhanx Biopharm Inc	Sistema de administración de medicamentos a base de glutatión
KR20180114970A (ko)	2009-05-06	2018-10-19	라보라토리 스킨 케어, 인크.	활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
TW201111392A (en)	2009-06-16	2011-04-01	Schering Corp	Novel [3,2-c] heteroaryl steroids as glucocorticoid receptor agonists, compositions and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3028400A (en) *		1962-04-03		Nsw steroid thioethers and process
US3105083A (en) *	1960-04-14	1963-09-24	Upjohn Co	21-organic sulfonates of 11, 17, 21-trioxygenated-3-keto pregnenes
US3171844A (en) *	1963-05-24	1965-03-02	Syntex Corp	20-(aliphatic hydrocarbonthio) and 20-(substituted aliphatic hydrocarbonthio) pregnane derivatives
FR2231374B1 (de) *	1973-05-30	1976-10-22	Jouveinal Sa
BE887518A (fr) *	1980-02-15	1981-08-13	Glaxo Group Ltd	Cartothioates d'androstanes
FR2510582B1 (fr) *	1981-07-30	1986-05-30	Sipsy	Steroides esterifies en la position 17 et thio-esterifies en la position 21, leur procede de preparation et leur application comme medicament
FR2551069B1 (fr) *	1983-08-26	1986-07-25	Jouveinal Sa	17-oxo-21-thioesters d'hydrocortisone, leur preparation et leurs applications comme medicament
US4488995A (en) *	1984-02-06	1984-12-18	E. R. Squibb & Sons, Inc.	Androstene-17β-alkylthiomethyl ethers

1986
- 1986-06-23 US US06/877,355 patent/US4861765A/en not_active Expired - Lifetime
- 1986-06-25 AT AT86108656T patent/ATE42306T1/de not_active IP Right Cessation
- 1986-06-25 ES ES556685A patent/ES8707256A1/es not_active Expired
- 1986-06-25 DE DE8686108656T patent/DE3662896D1/de not_active Expired
- 1986-06-25 JP JP14866786A patent/JPH0699468B2/ja not_active Expired - Fee Related
- 1986-06-25 EP EP86108656A patent/EP0208202B1/de not_active Expired

Also Published As

Publication number	Publication date
DE3662896D1 (en)	1989-05-24
EP0208202A1 (de)	1987-01-14
ES556685A0 (es)	1987-07-16
US4861765A (en)	1989-08-29
JPS6289694A (ja)	1987-04-24
JPH0699468B2 (ja)	1994-12-07
EP0208202B1 (de)	1989-04-19
ES8707256A1 (es)	1987-07-16

Legal Events

Date	Code	Title	Description
1989-11-15	UEP	Publication of translation of european patent specification
1996-03-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE3662896D1 (en)	1989-05-24	21-substituted thiosteroids
AU565898B2 (en)	1987-10-01	1,8-naphthyridine derivatives
DK0665844T3 (da)	2000-10-16	Substituerede benzylaminoquinuclidinforbindelser som antagonister af substans P
AR241531A1 (es)	1992-08-31	Un procedimiento para la preparacion derivados de 2-indolinona, y sus sales farmaceuticamente aceptables.
IE851205L (en)	1985-11-15	Beta-carbolines
KR850004492A (ko)	1985-07-15	옥시캄의 엔올 에테르 유도체의 제조방법
ES2000368A6 (es)	1988-02-16	Un procedimiento para preparar di-t-butilfenoles sustituidos
ES8306765A1 (es)	1983-06-01	"un procedimiento para preparar un derivado de antraciclina".
TR22986A (tr)	1989-01-02	Halka hetero atomlari haiz bisiklo-heptanlar,oktanlar ve nonanlar,bunlarin hazirlanmasi ve pestibid olarak kullanimlari
AU572888B2 (en)	1988-05-19	4-(3-alkynyloxy-2-hydroxy-propyl)-piperazin-i-yl-n- phenyl-acetamide derivatives
IT1201481B (it)	1989-02-02	Pantotenil derivati
ATE90356T1 (de)	1993-06-15	21-alkoxy-steroid-derivate.
DE3569380D1 (en)	1989-05-18	Pyridylphenylpyridazinone inotropic agents
ES8801669A1 (es)	1988-02-16	Un procedimiento para preparar nuevos compuestos de 2-oxa-0 aza-pregnano.
GB2182328B (en)	1989-09-20	Diphenyl ether derivatives
AU546960B2 (en)	1985-09-26	1,3-dihydro-2h-imidazol-2-one derivatives
FI903967A0 (fi)	1990-08-10	Nya imidazolderivat.
ATE21902T1 (de)	1986-09-15	6-substituierte tetrahydroimidazo(2,1a)phthalazine.
DE3564937D1 (en)	1988-10-20	Novel substituted phenyl ethers, process for their preparation, and their use in the preparation of substituted phenols
AU2167588A (en)	1989-03-02	Diphenyl ether herbicides
ES8308875A1 (es)	1983-10-01	Procedimiento para preparar 4-aminometil-5-acil-1,3-dihidro-2h-imidazol-2-onas.
DE3679224D1 (de)	1991-06-20	Carbacyclin-derivate.
FI874677A7 (fi)	1988-04-24	Laekemedel anvaendbart vid behandling av magsaor.
DK504788D0 (da)	1988-09-09	Fremgangsmaade til fremstilling af makrolidforbindelser
SU1314835A1 (ru)	2016-08-27	Вакуумный фоторезист