ATE424839T1 - Verwendung des lupinosids pa4 oder einer butanol- fraktion eines pueraria tuberosa-extrakts zur behandlung von typ-2 diabetes - Google Patents
Verwendung des lupinosids pa4 oder einer butanol- fraktion eines pueraria tuberosa-extrakts zur behandlung von typ-2 diabetesInfo
- Publication number
- ATE424839T1 ATE424839T1 AT04806442T AT04806442T ATE424839T1 AT E424839 T1 ATE424839 T1 AT E424839T1 AT 04806442 T AT04806442 T AT 04806442T AT 04806442 T AT04806442 T AT 04806442T AT E424839 T1 ATE424839 T1 AT E424839T1
- Authority
- AT
- Austria
- Prior art keywords
- lupinoside
- butanol fraction
- type
- diabetes
- treatment
- Prior art date
Links
- 208000001072 type 2 diabetes mellitus Diseases 0.000 title abstract 3
- 239000002034 butanolic fraction Substances 0.000 title abstract 2
- 241000826711 Pueraria tuberosa Species 0.000 title 1
- JVMAPBJQCGSNSC-UHFFFAOYSA-N lupinoside PA4 Natural products OC1C(O)C(O)C(C)OC1OC1C2(C)CCC3(C)C4(C)CCC5C(C)(CO)C(OC6C(C(O)C(O)C(O6)C(O)=O)OC6C(C(O)C(O)C(CO)O6)OC6C(C(O)C(O)C(C)O6)O)CCC5(C)C4CC=C3C2CC(C)(C)C1 JVMAPBJQCGSNSC-UHFFFAOYSA-N 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 101150110386 SLC2A4 gene Proteins 0.000 abstract 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical group N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
- 102000004877 Insulin Human genes 0.000 abstract 1
- 108090001061 Insulin Proteins 0.000 abstract 1
- 230000003190 augmentative effect Effects 0.000 abstract 1
- 210000000170 cell membrane Anatomy 0.000 abstract 1
- 229940125396 insulin Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000026731 phosphorylation Effects 0.000 abstract 1
- 238000006366 phosphorylation reaction Methods 0.000 abstract 1
- 230000019491 signal transduction Effects 0.000 abstract 1
- 230000005945 translocation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53533204P | 2004-01-09 | 2004-01-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE424839T1 true ATE424839T1 (de) | 2009-03-15 |
Family
ID=34837347
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04806442T ATE424839T1 (de) | 2004-01-09 | 2004-12-27 | Verwendung des lupinosids pa4 oder einer butanol- fraktion eines pueraria tuberosa-extrakts zur behandlung von typ-2 diabetes |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7276258B2 (de) |
| EP (1) | EP1715878B8 (de) |
| JP (1) | JP2007531709A (de) |
| CN (1) | CN1997379A (de) |
| AT (1) | ATE424839T1 (de) |
| CA (1) | CA2552954A1 (de) |
| DE (1) | DE602004019982D1 (de) |
| WO (1) | WO2005074958A2 (de) |
| ZA (1) | ZA200605690B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100363023C (zh) * | 2005-11-10 | 2008-01-23 | 济南大学 | 一种葛根活性成分柱色谱洗脱液的综合处理方法 |
| WO2008027807A2 (en) * | 2006-09-01 | 2008-03-06 | University Of Southern California | Control of diabetes and obesity |
| CN101266242B (zh) * | 2007-03-14 | 2012-07-04 | 中国科学院生物物理研究所 | 用于检测葡萄糖转运蛋白4上膜的探针和方法 |
| TWI532991B (zh) * | 2012-12-26 | 2016-05-11 | 國立中央大學 | 檢測可減脂化合物之方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08127538A (ja) * | 1994-10-31 | 1996-05-21 | Masakiyo Takahashi | 糖尿病治療薬 |
| EP1420657A1 (de) * | 2001-08-30 | 2004-05-26 | Council of Scientific and Industrial Research;an Indian Reg. body incorporated under Reg. of Societies Act (Act XXI of 1860) | Auf kräuter basierte nutraceutical formulierung für frauen bzw. schwangere und verfahren zu deren herstellung |
| US7014872B2 (en) * | 2002-03-26 | 2006-03-21 | Council Of Scientific And Industrial Research | Herbal nutraceutical formulation for diabetics and process for preparing the same |
-
2004
- 2004-03-25 US US10/809,645 patent/US7276258B2/en not_active Expired - Fee Related
- 2004-12-27 DE DE602004019982T patent/DE602004019982D1/de not_active Expired - Lifetime
- 2004-12-27 JP JP2006548420A patent/JP2007531709A/ja active Pending
- 2004-12-27 CA CA002552954A patent/CA2552954A1/en not_active Abandoned
- 2004-12-27 EP EP04806442A patent/EP1715878B8/de not_active Expired - Lifetime
- 2004-12-27 AT AT04806442T patent/ATE424839T1/de not_active IP Right Cessation
- 2004-12-27 WO PCT/IB2004/004273 patent/WO2005074958A2/en not_active Ceased
- 2004-12-27 CN CNA2004800423405A patent/CN1997379A/zh active Pending
-
2006
- 2006-07-11 ZA ZA200605690A patent/ZA200605690B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005074958A2 (en) | 2005-08-18 |
| EP1715878A2 (de) | 2006-11-02 |
| EP1715878B1 (de) | 2009-03-11 |
| ZA200605690B (en) | 2007-11-28 |
| CN1997379A (zh) | 2007-07-11 |
| EP1715878B8 (de) | 2009-08-05 |
| US20050153000A1 (en) | 2005-07-14 |
| US7276258B2 (en) | 2007-10-02 |
| DE602004019982D1 (de) | 2009-04-23 |
| WO2005074958A3 (en) | 2006-04-06 |
| JP2007531709A (ja) | 2007-11-08 |
| WO2005074958B1 (en) | 2006-05-04 |
| CA2552954A1 (en) | 2005-08-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |