ATE424915T1 - Verfahren und vorrichtung zur entfernung von feinteiligen partikeln durch perkolation im schüttgut - Google Patents

Verfahren und vorrichtung zur entfernung von feinteiligen partikeln durch perkolation im schüttgut

Info

Publication number
ATE424915T1
ATE424915T1 AT00988935T AT00988935T ATE424915T1 AT E424915 T1 ATE424915 T1 AT E424915T1 AT 00988935 T AT00988935 T AT 00988935T AT 00988935 T AT00988935 T AT 00988935T AT E424915 T1 ATE424915 T1 AT E424915T1
Authority
AT
Austria
Prior art keywords
fine particles
percolation
removal
bulk material
percolating
Prior art date
Application number
AT00988935T
Other languages
English (en)
Inventor
Michel Perrut
Original Assignee
Separex Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Separex Sa filed Critical Separex Sa
Application granted granted Critical
Publication of ATE424915T1 publication Critical patent/ATE424915T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D46/00—Filters or filtering processes specially modified for separating dispersed particles from gases or vapours
    • B01D46/42—Auxiliary equipment or operation thereof
    • B01D46/4272—Special valve constructions adapted to filters or filter elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D46/00—Filters or filtering processes specially modified for separating dispersed particles from gases or vapours
    • B01D46/30—Particle separators, e.g. dust precipitators, using loose filtering material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/006—Coating of the granules without description of the process or the device by which the granules are obtained
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Devices And Processes Conducted In The Presence Of Fluids And Solid Particles (AREA)
  • Soy Sauces And Products Related Thereto (AREA)
AT00988935T 1999-12-15 2000-12-15 Verfahren und vorrichtung zur entfernung von feinteiligen partikeln durch perkolation im schüttgut ATE424915T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9915834A FR2803538B1 (fr) 1999-12-15 1999-12-15 Procede et dispositif de captage de fines particules par percolation dans un lit de granules

Publications (1)

Publication Number Publication Date
ATE424915T1 true ATE424915T1 (de) 2009-03-15

Family

ID=9553299

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00988935T ATE424915T1 (de) 1999-12-15 2000-12-15 Verfahren und vorrichtung zur entfernung von feinteiligen partikeln durch perkolation im schüttgut

Country Status (7)

Country Link
US (1) US20020189454A1 (de)
EP (1) EP1239938B1 (de)
JP (1) JP2003517373A (de)
AT (1) ATE424915T1 (de)
DE (1) DE60041777D1 (de)
FR (1) FR2803538B1 (de)
WO (1) WO2001043853A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2830760B1 (fr) 2001-10-12 2004-06-04 Pf Medicament Procede de preparation d'un compose d'interaction de substances actives avec un support poreux par fluide supercritique
FR2830761B1 (fr) * 2001-10-12 2003-12-12 Pf Medicament Procede de preparation d'un compose d'interaction d'un derive anilide avec un support poreux par fluide supercritique
GB0229714D0 (en) * 2002-12-20 2003-01-29 Glaxo Group Ltd Novel apparatus and method
FR2854079B1 (fr) 2003-04-25 2007-11-30 Pf Medicament Procede de preparation de complexes moleculaires
JP4799032B2 (ja) * 2005-03-31 2011-10-19 株式会社大川原製作所 超臨界流体を用いた微粒子の製造装置
FR2943539B1 (fr) 2009-03-31 2011-07-22 Ethypharm Sa Composition pharmaceutique comprenant un macrolide immunosuppresseur de la famille des limus.
FR2943543B1 (fr) * 2009-03-31 2013-02-08 Separex Sa Procede de preparation de compositions pharmaceutiques comprenant des particules fines de substance active.
US10206873B1 (en) 2017-08-04 2019-02-19 Colorado Can Llc Dry powder formation using a variably constrained, divided pathway for mixing fluid streams

Family Cites Families (35)

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US4734451A (en) * 1983-09-01 1988-03-29 Battelle Memorial Institute Supercritical fluid molecular spray thin films and fine powders
US4582731A (en) * 1983-09-01 1986-04-15 Battelle Memorial Institute Supercritical fluid molecular spray film deposition and powder formation
DE3536622A1 (de) * 1985-10-15 1987-04-16 Krupp Gmbh Verfahren und vorrichtung zur gewinnung fester stoffe aus fluessigen stoffgemischen
US4801411A (en) * 1986-06-05 1989-01-31 Southwest Research Institute Method and apparatus for producing monosize ceramic particles
GB2191715B (en) * 1986-06-17 1990-07-25 Midrex Int Bv Method and apparatus for dedusting and desulfurizing gases
US4822497A (en) * 1987-09-22 1989-04-18 Modar, Inc. Method for solids separation in a wet oxidation type process
DE3744329A1 (de) * 1987-12-28 1989-07-06 Schwarz Pharma Gmbh Verfahren zur herstellung einer mindestens einen wirkstoff und einen traeger umfassenden zubereitung
US5707634A (en) * 1988-10-05 1998-01-13 Pharmacia & Upjohn Company Finely divided solid crystalline powders via precipitation into an anti-solvent
US4970093A (en) * 1990-04-12 1990-11-13 University Of Colorado Foundation Chemical deposition methods using supercritical fluid solutions
GB9100643D0 (en) * 1991-01-11 1991-02-27 Shaffery Michael J Filter system
US6063910A (en) * 1991-11-14 2000-05-16 The Trustees Of Princeton University Preparation of protein microparticles by supercritical fluid precipitation
US5639441A (en) * 1992-03-06 1997-06-17 Board Of Regents Of University Of Colorado Methods for fine particle formation
US5301664A (en) * 1992-03-06 1994-04-12 Sievers Robert E Methods and apparatus for drug delivery using supercritical solutions
WO1993022022A1 (fr) * 1992-04-29 1993-11-11 Institut Français Du Petrole Procede et dispositif de fractionnement d'un melange en lit mobile simule en presence d'un gaz comprime, d'un fluide supercritique ou d'un liquide subcritique
US5389263A (en) * 1992-05-20 1995-02-14 Phasex Corporation Gas anti-solvent recrystallization and application for the separation and subsequent processing of RDX and HMX
AU5171293A (en) * 1992-10-14 1994-05-09 Regents Of The University Of Colorado, The Ion-pairing of drugs for improved efficacy and delivery
US5290604A (en) * 1992-12-18 1994-03-01 Union Carbide Chemicals & Plastics Technology Corporation Methods and apparatus for spraying solvent-borne compositions with reduced solvent emission using compressed fluids and separating solvent
GB9313650D0 (en) * 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
GB9313642D0 (en) * 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
BR9408015A (pt) * 1993-11-08 1996-12-17 Gillette Co Processos para preparar material em partículas para formar material em partículas para controlar a transpiração e para evitar o mau-odor devido à transpiração em um ser humano material em antiperpirante ou desodorante
GB9413202D0 (en) * 1994-06-30 1994-08-24 Univ Bradford Method and apparatus for the formation of particles
EP0706821A1 (de) * 1994-10-06 1996-04-17 Centre De Microencapsulation Verfahren zum Beschichten von Partikeln
KR100508910B1 (ko) * 1995-10-17 2006-04-20 알티피 파마 코포레이션 불용성약물방출
US5803966A (en) * 1995-11-01 1998-09-08 Alcon Laboratories, Inc. Process for sizing prednisolone acetate using a supercritical fluid anti-solvent
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US5874029A (en) * 1996-10-09 1999-02-23 The University Of Kansas Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent
DE19711393C1 (de) * 1997-03-19 1998-08-13 Fraunhofer Ges Forschung Verfahren zum Mikroverkapseln von Partikeln
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US6620351B2 (en) * 2000-05-24 2003-09-16 Auburn University Method of forming nanoparticles and microparticles of controllable size using supercritical fluids with enhanced mass transfer
US6869551B2 (en) * 2001-03-30 2005-03-22 Picoliter Inc. Precipitation of solid particles from droplets formed using focused acoustic energy
DK1435916T3 (da) * 2001-10-10 2006-08-21 Boehringer Ingelheim Pharma Pulverbearbejdning med tryksatte gasformige fluider
US7722771B2 (en) * 2004-04-12 2010-05-25 Thar Technologies, Inc. Continuous processing and solids handling in near-critical and supercritical fluids

Also Published As

Publication number Publication date
DE60041777D1 (de) 2009-04-23
WO2001043853A1 (fr) 2001-06-21
JP2003517373A (ja) 2003-05-27
EP1239938A1 (de) 2002-09-18
FR2803538B1 (fr) 2002-06-07
EP1239938B1 (de) 2009-03-11
FR2803538A1 (fr) 2001-07-13
US20020189454A1 (en) 2002-12-19

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