ATE426398T1 - Prozess zur herstellung einer dexamethason enthaltenden formulierung zur oralen anwendung - Google Patents

Prozess zur herstellung einer dexamethason enthaltenden formulierung zur oralen anwendung

Info

Publication number
ATE426398T1
ATE426398T1 AT04712644T AT04712644T ATE426398T1 AT E426398 T1 ATE426398 T1 AT E426398T1 AT 04712644 T AT04712644 T AT 04712644T AT 04712644 T AT04712644 T AT 04712644T AT E426398 T1 ATE426398 T1 AT E426398T1
Authority
AT
Austria
Prior art keywords
producing
formulation containing
oral use
dexamethasone
containing dexamethasone
Prior art date
Application number
AT04712644T
Other languages
English (en)
Inventor
Paul Rice
Nicholas Mchardy
Original Assignee
Constant Res & Dev Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Constant Res & Dev Ltd filed Critical Constant Res & Dev Ltd
Application granted granted Critical
Publication of ATE426398T1 publication Critical patent/ATE426398T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT04712644T 2003-02-20 2004-02-19 Prozess zur herstellung einer dexamethason enthaltenden formulierung zur oralen anwendung ATE426398T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44817403P 2003-02-20 2003-02-20

Publications (1)

Publication Number Publication Date
ATE426398T1 true ATE426398T1 (de) 2009-04-15

Family

ID=32908546

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04712644T ATE426398T1 (de) 2003-02-20 2004-02-19 Prozess zur herstellung einer dexamethason enthaltenden formulierung zur oralen anwendung

Country Status (5)

Country Link
US (1) US20060034915A1 (de)
EP (1) EP1594471B1 (de)
AT (1) ATE426398T1 (de)
DE (1) DE602004020187D1 (de)
WO (1) WO2004073685A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101346393B (zh) 2005-11-02 2015-07-22 普洛体维生物治疗公司 修饰的siRNA分子及其应用
US7915399B2 (en) 2006-06-09 2011-03-29 Protiva Biotherapeutics, Inc. Modified siRNA molecules and uses thereof
GB2455539B (en) * 2007-12-12 2012-01-18 Cambridge Entpr Ltd Anti-inflammatory compositions and combinations
CN105997866B (zh) * 2016-07-13 2019-08-20 成都明慈医药科技有限公司 一种含地塞米松的混悬剂及其制备方法
US10537585B2 (en) 2017-12-18 2020-01-21 Dexcel Pharma Technologies Ltd. Compositions comprising dexamethasone
WO2020168106A1 (en) 2019-02-13 2020-08-20 Notable Labs, Inc. Combinations of agonists of protein kinase c with steroids or retinoic acids for the treatment of cancer

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2946298A (en) * 1957-11-13 1960-07-26 Arthur Colton Company Compression coating tablet press
NL125158C (de) * 1959-10-01
GB970440A (en) * 1961-08-14 1964-09-23 Merck & Co Inc Anti-inflammatory compositions comprising steroids and indole derivatives
US3231468A (en) * 1962-07-02 1966-01-25 Merck & Co Inc Dexamethasone-cyproheptadine oral antiflammatory compositions
JPS5759803A (en) * 1980-09-30 1982-04-10 Takeda Chem Ind Ltd Granule of l-sodium ascorbate, its preparation, and tablet comprising it
DE3690101C2 (de) * 1985-03-01 1995-06-08 Freunt Ind Co Ltd Verfahren und Vorrichtung zum Überziehen von fluidisierten Körnern durch Besprühen
US5686106A (en) * 1995-05-17 1997-11-11 The Procter & Gamble Company Pharmaceutical dosage form for colonic delivery
AU739031B2 (en) * 1996-11-15 2001-10-04 Procter & Gamble Company, The Pharmaceutical dosage form for colonic delivery
US7829555B1 (en) * 1997-02-11 2010-11-09 The University Of Manchester Drug targeting
IT1303692B1 (it) * 1998-11-03 2001-02-23 Chiesi Farma Spa Procedimento per la preparazione di sospensioni di particelle difarmaci da somministrare per inalazione.

Also Published As

Publication number Publication date
US20060034915A1 (en) 2006-02-16
DE602004020187D1 (de) 2009-05-07
WO2004073685A1 (en) 2004-09-02
EP1594471B1 (de) 2009-03-25
EP1594471A1 (de) 2005-11-16

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