ATE426814T1 - Markierungsmittel mit einer vielzahl von farbtínen - Google Patents
Markierungsmittel mit einer vielzahl von farbtínenInfo
- Publication number
- ATE426814T1 ATE426814T1 AT99945277T AT99945277T ATE426814T1 AT E426814 T1 ATE426814 T1 AT E426814T1 AT 99945277 T AT99945277 T AT 99945277T AT 99945277 T AT99945277 T AT 99945277T AT E426814 T1 ATE426814 T1 AT E426814T1
- Authority
- AT
- Austria
- Prior art keywords
- different
- colors
- variety
- reagent
- signal
- Prior art date
Links
- 239000003086 colorant Substances 0.000 title 1
- 239000003550 marker Substances 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/918—Immunological
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/924—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis using nanostructure as support of dna analysis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/925—Bioelectrical
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Luminescent Compositions (AREA)
- Road Signs Or Road Markings (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/146,984 US6642062B2 (en) | 1998-09-03 | 1998-09-03 | Multihued labels |
| US09/332,613 US6492125B2 (en) | 1998-09-03 | 1999-06-14 | Method to assess library X library interactions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE426814T1 true ATE426814T1 (de) | 2009-04-15 |
Family
ID=22519872
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99945277T ATE426814T1 (de) | 1998-09-03 | 1999-08-30 | Markierungsmittel mit einer vielzahl von farbtínen |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US6642062B2 (de) |
| EP (1) | EP1942346A1 (de) |
| AT (1) | ATE426814T1 (de) |
| DE (1) | DE69940639D1 (de) |
| IL (2) | IL141759A (de) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2255599C (en) | 1996-04-25 | 2006-09-05 | Bioarray Solutions, Llc | Light-controlled electrokinetic assembly of particles near surfaces |
| US7079241B2 (en) * | 2000-04-06 | 2006-07-18 | Invitrogen Corp. | Spatial positioning of spectrally labeled beads |
| US8264680B2 (en) * | 1999-05-28 | 2012-09-11 | Yokogawa Electric Corporation | Biochip reader and electrophoresis system |
| EP1983331B1 (de) * | 1999-05-28 | 2011-07-13 | Yokogawa Electric Corporation | Optische Anordnung zur Auswertung eines Biochips |
| AU5870800A (en) * | 1999-06-09 | 2000-12-28 | Ljl Biosystems, Inc. | Cell-signaling assays |
| US6673554B1 (en) * | 1999-06-14 | 2004-01-06 | Trellie Bioinformatics, Inc. | Protein localization assays for toxicity and antidotes thereto |
| DE60040603D1 (de) * | 1999-08-17 | 2008-12-04 | Luminex Corp | Verfahren zur analyse einer mehrzahl von proben verschiedenen ursprungs auf einen analyten |
| US20020090650A1 (en) * | 2000-04-06 | 2002-07-11 | Quantum Dot Corporation | Two-dimensional spectral imaging system |
| US9709559B2 (en) | 2000-06-21 | 2017-07-18 | Bioarray Solutions, Ltd. | Multianalyte molecular analysis using application-specific random particle arrays |
| DE60117556T2 (de) | 2000-06-21 | 2006-11-02 | Bioarray Solutions Ltd. | Multianalytische molekularanalyse durch verwendung anwendungsspezifischer zufallspartikelarrays |
| US7691645B2 (en) * | 2001-01-09 | 2010-04-06 | Agilent Technologies, Inc. | Immunosubtraction method |
| US7015047B2 (en) * | 2001-01-26 | 2006-03-21 | Aviva Biosciences Corporation | Microdevices having a preferential axis of magnetization and uses thereof |
| US7811768B2 (en) * | 2001-01-26 | 2010-10-12 | Aviva Biosciences Corporation | Microdevice containing photorecognizable coding patterns and methods of using and producing the same |
| US7262063B2 (en) | 2001-06-21 | 2007-08-28 | Bio Array Solutions, Ltd. | Directed assembly of functional heterostructures |
| US20050164261A1 (en) * | 2001-10-09 | 2005-07-28 | Chandler Don J. | Multiplexed analysis of clinical specimens apparatus and methods |
| US8148171B2 (en) | 2001-10-09 | 2012-04-03 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and methods |
| ES2661167T3 (es) | 2001-10-15 | 2018-03-27 | Bioarray Solutions Ltd. | Análisis multiplexado de loci polimórficos mediante consulta simultánea y detección mediada por enzimas |
| US7771951B2 (en) * | 2001-12-03 | 2010-08-10 | Amgen Fremont Inc. | Antibody categorization based on binding characteristics |
| AU2003282765A1 (en) * | 2002-10-07 | 2004-05-04 | Trellis Bioscience, Inc. | Multihued labels |
| US7526114B2 (en) | 2002-11-15 | 2009-04-28 | Bioarray Solutions Ltd. | Analysis, secure access to, and transmission of array images |
| US8796030B2 (en) * | 2003-07-12 | 2014-08-05 | Parallel Synthesis Technologies, Inc. | Methods for optically encoding an object with upconverting materials and compositions used therein |
| WO2005012497A2 (en) * | 2003-07-29 | 2005-02-10 | Trellis Bioscience, Inc. | Translocation tagging |
| US7927796B2 (en) | 2003-09-18 | 2011-04-19 | Bioarray Solutions, Ltd. | Number coding for identification of subtypes of coded types of solid phase carriers |
| JP4564959B2 (ja) | 2003-09-22 | 2010-10-20 | バイオアレイ ソリューションズ リミテッド | 生体分子に共有結合できる、複数の官能基を持つ表面固定化高分子電解質 |
| US20050064435A1 (en) * | 2003-09-24 | 2005-03-24 | Xing Su | Programmable molecular barcodes |
| WO2005042763A2 (en) | 2003-10-28 | 2005-05-12 | Bioarray Solutions Ltd. | Optimization of gene expression analysis using immobilized capture probes |
| WO2005045060A2 (en) | 2003-10-29 | 2005-05-19 | Bioarray Solutions, Ltd. | Multiplexed nucleic acid analysis by fragmentation of double-stranded dna |
| US7413868B2 (en) * | 2003-11-05 | 2008-08-19 | Trellis Bioscience, Inc. | Use of particulate labels in bioanalyte detection methods |
| US7659890B2 (en) | 2004-03-19 | 2010-02-09 | Microsoft Corporation | Automatic height adjustment for electronic highlighter pens and mousing devices |
| US7848889B2 (en) | 2004-08-02 | 2010-12-07 | Bioarray Solutions, Ltd. | Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification |
| US8927892B2 (en) | 2004-10-22 | 2015-01-06 | Parallel Synthesis Technologies | Rare earth downconverting phosphor compositions for optically encoding objects and methods and apparatus relating to same |
| US7507588B2 (en) * | 2005-04-20 | 2009-03-24 | Becton, Dickinson And Company | Multiplex microparticle system |
| US8486629B2 (en) * | 2005-06-01 | 2013-07-16 | Bioarray Solutions, Ltd. | Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation |
| WO2007051035A1 (en) * | 2005-10-28 | 2007-05-03 | Parallel Synthesis Technologies, Inc. | Methods for fabricating optically encoded particles and methods for optically encoding objects with such particles |
| US20090220989A1 (en) * | 2005-12-05 | 2009-09-03 | Guava Technologies | Particle-Based Analyte Characterization |
| WO2008008858A2 (en) * | 2006-07-12 | 2008-01-17 | Trellis Bioscience, Inc. | Cellspot™ applications |
| WO2008153836A2 (en) * | 2007-05-31 | 2008-12-18 | President And Fellows Of Harvard College | Target-locking acquisition with real-time confocal (tarc) microscopy |
| JP5808536B2 (ja) | 2007-10-25 | 2015-11-10 | トレリス バイオサイエンス、インク. | 抗rsvgタンパク質抗体 |
| DE102007052517A1 (de) * | 2007-10-29 | 2009-04-30 | Autoimmun Diagnostika Gmbh | ELISPOT-Verfahren mit zwei Filtersystemen |
| EP2224227B1 (de) * | 2008-01-16 | 2014-09-03 | Nippon Telegraph and Telephone Corporation | Oberflachenplasmaresonanzmessvorrichtung, probenvorrichtung und messmethode |
| EP2582389B1 (de) | 2010-06-16 | 2018-02-21 | Trellis Bioscience, LLC | Hochaffine menschliche antikörper zu menschlichem cytomegalovirus-gb-protein |
| EP3225990B1 (de) * | 2010-08-30 | 2020-07-08 | Konica Minolta, Inc. | Partikel zum einfärben von gewebe |
| JP6127972B2 (ja) | 2011-09-09 | 2017-05-17 | コニカミノルタ株式会社 | 組織染色方法 |
| CN114717296B (zh) | 2012-02-03 | 2025-04-04 | 加州理工学院 | 多路生化测定中信号的编码和解码 |
| WO2013146741A1 (ja) * | 2012-03-30 | 2013-10-03 | コニカミノルタ株式会社 | 組織染色方法 |
| WO2014022827A1 (en) | 2012-08-03 | 2014-02-06 | California Institute Of Technology | Multiplexing and quantification in pcr with reduced hardware and requirements |
| WO2014031902A2 (en) | 2012-08-23 | 2014-02-27 | The Regents Of The University Of California | Spectrally encoded microbeads and methods and devices for making and using same |
| US20170016911A1 (en) * | 2014-03-24 | 2017-01-19 | Konica Minolta, Inc. | Method for quantifying biological material based on multiple immunostaining |
| CN109642252A (zh) | 2016-06-17 | 2019-04-16 | 加州理工学院 | 核酸反应及相关方法和组合物 |
| CN107192818B (zh) * | 2017-05-23 | 2018-06-29 | 重庆天之助生物科技有限公司 | 一种微粒子色度聚类分析方法及试剂盒 |
| WO2019204357A1 (en) | 2018-04-17 | 2019-10-24 | ChromaCode, Inc. | Methods and systems for multiplex analysis |
| US12203129B2 (en) | 2018-07-03 | 2025-01-21 | ChromaCode, Inc. | Formulations and signal encoding and decoding methods for massively multiplexed biochemical assays |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3322373C2 (de) * | 1983-05-19 | 1986-12-04 | Ioannis Dr. 3000 Hannover Tripatzis | Testmittel und Verfahren zum Nachweis von Antigenen und/oder Antikörpern |
| US5202231A (en) | 1987-04-01 | 1993-04-13 | Drmanac Radoje T | Method of sequencing of genomes by hybridization of oligonucleotide probes |
| US5525464A (en) | 1987-04-01 | 1996-06-11 | Hyseq, Inc. | Method of sequencing by hybridization of oligonucleotide probes |
| US5300425A (en) * | 1987-10-13 | 1994-04-05 | Terrapin Technologies, Inc. | Method to produce immunodiagnostic reagents |
| US5340474A (en) | 1988-03-24 | 1994-08-23 | Terrapin Technologies, Inc. | Panels of analyte-binding ligands |
| US5326692B1 (en) * | 1992-05-13 | 1996-04-30 | Molecular Probes Inc | Fluorescent microparticles with controllable enhanced stokes shift |
| US5723218A (en) | 1990-04-16 | 1998-03-03 | Molecular Probes, Inc. | Dipyrrometheneboron difluoride labeled flourescent microparticles |
| US5567588A (en) | 1990-06-11 | 1996-10-22 | University Research Corporation | Systematic evolution of ligands by exponential enrichment: Solution SELEX |
| US5665822A (en) | 1991-10-07 | 1997-09-09 | Landec Corporation | Thermoplastic Elastomers |
| US5369036A (en) | 1992-07-02 | 1994-11-29 | Becton, Dickinson And Company | Enhancement of signal in immunoassays using microparticles which contain different detectable substances |
| US5565324A (en) * | 1992-10-01 | 1996-10-15 | The Trustees Of Columbia University In The City Of New York | Complex combinatorial chemical libraries encoded with tags |
| DK0665897T3 (da) * | 1992-10-01 | 2003-10-20 | Univ Columbia | Komplekse, kombinatoriske, kemiske biblioteker kodet med etiketter |
| US5721099A (en) * | 1992-10-01 | 1998-02-24 | Trustees Of Columbia University In The City Of New York | Complex combinatorial chemical libraries encoded with tags |
| US5356784A (en) * | 1993-03-30 | 1994-10-18 | Terrapin Technologies, Inc. | Determination of concentration by affinity titration |
| FR2707658B1 (fr) | 1993-07-12 | 1995-11-24 | Prolabo Sa | Latex fluorescent comportant au moins deux fluorochromes, procédé d'obtention et application dudit latex comme marqueur, notamment en biologie. |
| CN1154640C (zh) * | 1993-10-01 | 2004-06-23 | 纽约市哥伦比亚大学理事 | 用标示物编码的多元组合化学库 |
| JPH10500951A (ja) * | 1994-05-23 | 1998-01-27 | スミスクライン・ビーチャム・コーポレイション | コードされた組合せライブラリー |
| US6210900B1 (en) * | 1995-05-23 | 2001-04-03 | Smithkline Beecham Corporation | Method of encoding a series of combinatorial libraries and developing structure activity relationships |
| DE69638321D1 (de) | 1995-10-11 | 2011-03-03 | Luminex Corp | Gleichzeitige mehrfachanalyse klinischer proben |
| US5981180A (en) | 1995-10-11 | 1999-11-09 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and methods |
| NO308755B1 (no) * | 1996-12-20 | 2000-10-23 | Iystein Fodstad | FremgangsmÕte til karakterisering av unormale celler, anvendelse og sett for utførelse av fremgangsmÕten |
| US6023540A (en) | 1997-03-14 | 2000-02-08 | Trustees Of Tufts College | Fiber optic sensor with encoded microspheres |
| US5834203A (en) | 1997-08-25 | 1998-11-10 | Applied Spectral Imaging | Method for classification of pixels into groups according to their spectra using a plurality of wide band filters and hardwire therefore |
| AU1080999A (en) | 1997-10-14 | 1999-05-03 | Luminex Corporation | Precision fluorescently dyed particles and methods of making and using same |
| CA2335951C (en) * | 1998-06-24 | 2013-07-30 | Mark S. Chee | Decoding of array sensors with microspheres |
-
1998
- 1998-09-03 US US09/146,984 patent/US6642062B2/en not_active Expired - Lifetime
-
1999
- 1999-06-14 US US09/332,613 patent/US6492125B2/en not_active Expired - Fee Related
- 1999-08-30 EP EP08006176A patent/EP1942346A1/de not_active Withdrawn
- 1999-08-30 DE DE69940639T patent/DE69940639D1/de not_active Expired - Lifetime
- 1999-08-30 AT AT99945277T patent/ATE426814T1/de not_active IP Right Cessation
-
2001
- 2001-03-01 IL IL141759A patent/IL141759A/en not_active IP Right Cessation
-
2003
- 2003-10-02 US US10/678,414 patent/US20040072233A1/en not_active Abandoned
-
2009
- 2009-07-16 IL IL199919A patent/IL199919A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US20010044116A1 (en) | 2001-11-22 |
| US20010031464A1 (en) | 2001-10-18 |
| IL199919A (en) | 2011-05-31 |
| DE69940639D1 (de) | 2009-05-07 |
| US6492125B2 (en) | 2002-12-10 |
| US6642062B2 (en) | 2003-11-04 |
| EP1942346A1 (de) | 2008-07-09 |
| IL141759A (en) | 2010-05-31 |
| US20040072233A1 (en) | 2004-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |