ATE426814T1 - Markierungsmittel mit einer vielzahl von farbtínen - Google Patents

Markierungsmittel mit einer vielzahl von farbtínen

Info

Publication number
ATE426814T1
ATE426814T1 AT99945277T AT99945277T ATE426814T1 AT E426814 T1 ATE426814 T1 AT E426814T1 AT 99945277 T AT99945277 T AT 99945277T AT 99945277 T AT99945277 T AT 99945277T AT E426814 T1 ATE426814 T1 AT E426814T1
Authority
AT
Austria
Prior art keywords
different
colors
variety
reagent
signal
Prior art date
Application number
AT99945277T
Other languages
English (en)
Inventor
Lawrence Kauvar
John Sedat
Original Assignee
Trellis Bioscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trellis Bioscience Inc filed Critical Trellis Bioscience Inc
Application granted granted Critical
Publication of ATE426814T1 publication Critical patent/ATE426814T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/918Immunological
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/924Specified use of nanostructure for medical, immunological, body treatment, or diagnosis using nanostructure as support of dna analysis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/925Bioelectrical

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Luminescent Compositions (AREA)
  • Road Signs Or Road Markings (AREA)
  • Cosmetics (AREA)
AT99945277T 1998-09-03 1999-08-30 Markierungsmittel mit einer vielzahl von farbtínen ATE426814T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/146,984 US6642062B2 (en) 1998-09-03 1998-09-03 Multihued labels
US09/332,613 US6492125B2 (en) 1998-09-03 1999-06-14 Method to assess library X library interactions

Publications (1)

Publication Number Publication Date
ATE426814T1 true ATE426814T1 (de) 2009-04-15

Family

ID=22519872

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99945277T ATE426814T1 (de) 1998-09-03 1999-08-30 Markierungsmittel mit einer vielzahl von farbtínen

Country Status (5)

Country Link
US (3) US6642062B2 (de)
EP (1) EP1942346A1 (de)
AT (1) ATE426814T1 (de)
DE (1) DE69940639D1 (de)
IL (2) IL141759A (de)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2255599C (en) 1996-04-25 2006-09-05 Bioarray Solutions, Llc Light-controlled electrokinetic assembly of particles near surfaces
US7079241B2 (en) * 2000-04-06 2006-07-18 Invitrogen Corp. Spatial positioning of spectrally labeled beads
US8264680B2 (en) * 1999-05-28 2012-09-11 Yokogawa Electric Corporation Biochip reader and electrophoresis system
EP1983331B1 (de) * 1999-05-28 2011-07-13 Yokogawa Electric Corporation Optische Anordnung zur Auswertung eines Biochips
AU5870800A (en) * 1999-06-09 2000-12-28 Ljl Biosystems, Inc. Cell-signaling assays
US6673554B1 (en) * 1999-06-14 2004-01-06 Trellie Bioinformatics, Inc. Protein localization assays for toxicity and antidotes thereto
DE60040603D1 (de) * 1999-08-17 2008-12-04 Luminex Corp Verfahren zur analyse einer mehrzahl von proben verschiedenen ursprungs auf einen analyten
US20020090650A1 (en) * 2000-04-06 2002-07-11 Quantum Dot Corporation Two-dimensional spectral imaging system
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
DE60117556T2 (de) 2000-06-21 2006-11-02 Bioarray Solutions Ltd. Multianalytische molekularanalyse durch verwendung anwendungsspezifischer zufallspartikelarrays
US7691645B2 (en) * 2001-01-09 2010-04-06 Agilent Technologies, Inc. Immunosubtraction method
US7015047B2 (en) * 2001-01-26 2006-03-21 Aviva Biosciences Corporation Microdevices having a preferential axis of magnetization and uses thereof
US7811768B2 (en) * 2001-01-26 2010-10-12 Aviva Biosciences Corporation Microdevice containing photorecognizable coding patterns and methods of using and producing the same
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
US20050164261A1 (en) * 2001-10-09 2005-07-28 Chandler Don J. Multiplexed analysis of clinical specimens apparatus and methods
US8148171B2 (en) 2001-10-09 2012-04-03 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
ES2661167T3 (es) 2001-10-15 2018-03-27 Bioarray Solutions Ltd. Análisis multiplexado de loci polimórficos mediante consulta simultánea y detección mediada por enzimas
US7771951B2 (en) * 2001-12-03 2010-08-10 Amgen Fremont Inc. Antibody categorization based on binding characteristics
AU2003282765A1 (en) * 2002-10-07 2004-05-04 Trellis Bioscience, Inc. Multihued labels
US7526114B2 (en) 2002-11-15 2009-04-28 Bioarray Solutions Ltd. Analysis, secure access to, and transmission of array images
US8796030B2 (en) * 2003-07-12 2014-08-05 Parallel Synthesis Technologies, Inc. Methods for optically encoding an object with upconverting materials and compositions used therein
WO2005012497A2 (en) * 2003-07-29 2005-02-10 Trellis Bioscience, Inc. Translocation tagging
US7927796B2 (en) 2003-09-18 2011-04-19 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
JP4564959B2 (ja) 2003-09-22 2010-10-20 バイオアレイ ソリューションズ リミテッド 生体分子に共有結合できる、複数の官能基を持つ表面固定化高分子電解質
US20050064435A1 (en) * 2003-09-24 2005-03-24 Xing Su Programmable molecular barcodes
WO2005042763A2 (en) 2003-10-28 2005-05-12 Bioarray Solutions Ltd. Optimization of gene expression analysis using immobilized capture probes
WO2005045060A2 (en) 2003-10-29 2005-05-19 Bioarray Solutions, Ltd. Multiplexed nucleic acid analysis by fragmentation of double-stranded dna
US7413868B2 (en) * 2003-11-05 2008-08-19 Trellis Bioscience, Inc. Use of particulate labels in bioanalyte detection methods
US7659890B2 (en) 2004-03-19 2010-02-09 Microsoft Corporation Automatic height adjustment for electronic highlighter pens and mousing devices
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
US8927892B2 (en) 2004-10-22 2015-01-06 Parallel Synthesis Technologies Rare earth downconverting phosphor compositions for optically encoding objects and methods and apparatus relating to same
US7507588B2 (en) * 2005-04-20 2009-03-24 Becton, Dickinson And Company Multiplex microparticle system
US8486629B2 (en) * 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
WO2007051035A1 (en) * 2005-10-28 2007-05-03 Parallel Synthesis Technologies, Inc. Methods for fabricating optically encoded particles and methods for optically encoding objects with such particles
US20090220989A1 (en) * 2005-12-05 2009-09-03 Guava Technologies Particle-Based Analyte Characterization
WO2008008858A2 (en) * 2006-07-12 2008-01-17 Trellis Bioscience, Inc. Cellspot™ applications
WO2008153836A2 (en) * 2007-05-31 2008-12-18 President And Fellows Of Harvard College Target-locking acquisition with real-time confocal (tarc) microscopy
JP5808536B2 (ja) 2007-10-25 2015-11-10 トレリス バイオサイエンス、インク. 抗rsvgタンパク質抗体
DE102007052517A1 (de) * 2007-10-29 2009-04-30 Autoimmun Diagnostika Gmbh ELISPOT-Verfahren mit zwei Filtersystemen
EP2224227B1 (de) * 2008-01-16 2014-09-03 Nippon Telegraph and Telephone Corporation Oberflachenplasmaresonanzmessvorrichtung, probenvorrichtung und messmethode
EP2582389B1 (de) 2010-06-16 2018-02-21 Trellis Bioscience, LLC Hochaffine menschliche antikörper zu menschlichem cytomegalovirus-gb-protein
EP3225990B1 (de) * 2010-08-30 2020-07-08 Konica Minolta, Inc. Partikel zum einfärben von gewebe
JP6127972B2 (ja) 2011-09-09 2017-05-17 コニカミノルタ株式会社 組織染色方法
CN114717296B (zh) 2012-02-03 2025-04-04 加州理工学院 多路生化测定中信号的编码和解码
WO2013146741A1 (ja) * 2012-03-30 2013-10-03 コニカミノルタ株式会社 組織染色方法
WO2014022827A1 (en) 2012-08-03 2014-02-06 California Institute Of Technology Multiplexing and quantification in pcr with reduced hardware and requirements
WO2014031902A2 (en) 2012-08-23 2014-02-27 The Regents Of The University Of California Spectrally encoded microbeads and methods and devices for making and using same
US20170016911A1 (en) * 2014-03-24 2017-01-19 Konica Minolta, Inc. Method for quantifying biological material based on multiple immunostaining
CN109642252A (zh) 2016-06-17 2019-04-16 加州理工学院 核酸反应及相关方法和组合物
CN107192818B (zh) * 2017-05-23 2018-06-29 重庆天之助生物科技有限公司 一种微粒子色度聚类分析方法及试剂盒
WO2019204357A1 (en) 2018-04-17 2019-10-24 ChromaCode, Inc. Methods and systems for multiplex analysis
US12203129B2 (en) 2018-07-03 2025-01-21 ChromaCode, Inc. Formulations and signal encoding and decoding methods for massively multiplexed biochemical assays

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3322373C2 (de) * 1983-05-19 1986-12-04 Ioannis Dr. 3000 Hannover Tripatzis Testmittel und Verfahren zum Nachweis von Antigenen und/oder Antikörpern
US5202231A (en) 1987-04-01 1993-04-13 Drmanac Radoje T Method of sequencing of genomes by hybridization of oligonucleotide probes
US5525464A (en) 1987-04-01 1996-06-11 Hyseq, Inc. Method of sequencing by hybridization of oligonucleotide probes
US5300425A (en) * 1987-10-13 1994-04-05 Terrapin Technologies, Inc. Method to produce immunodiagnostic reagents
US5340474A (en) 1988-03-24 1994-08-23 Terrapin Technologies, Inc. Panels of analyte-binding ligands
US5326692B1 (en) * 1992-05-13 1996-04-30 Molecular Probes Inc Fluorescent microparticles with controllable enhanced stokes shift
US5723218A (en) 1990-04-16 1998-03-03 Molecular Probes, Inc. Dipyrrometheneboron difluoride labeled flourescent microparticles
US5567588A (en) 1990-06-11 1996-10-22 University Research Corporation Systematic evolution of ligands by exponential enrichment: Solution SELEX
US5665822A (en) 1991-10-07 1997-09-09 Landec Corporation Thermoplastic Elastomers
US5369036A (en) 1992-07-02 1994-11-29 Becton, Dickinson And Company Enhancement of signal in immunoassays using microparticles which contain different detectable substances
US5565324A (en) * 1992-10-01 1996-10-15 The Trustees Of Columbia University In The City Of New York Complex combinatorial chemical libraries encoded with tags
DK0665897T3 (da) * 1992-10-01 2003-10-20 Univ Columbia Komplekse, kombinatoriske, kemiske biblioteker kodet med etiketter
US5721099A (en) * 1992-10-01 1998-02-24 Trustees Of Columbia University In The City Of New York Complex combinatorial chemical libraries encoded with tags
US5356784A (en) * 1993-03-30 1994-10-18 Terrapin Technologies, Inc. Determination of concentration by affinity titration
FR2707658B1 (fr) 1993-07-12 1995-11-24 Prolabo Sa Latex fluorescent comportant au moins deux fluorochromes, procédé d'obtention et application dudit latex comme marqueur, notamment en biologie.
CN1154640C (zh) * 1993-10-01 2004-06-23 纽约市哥伦比亚大学理事 用标示物编码的多元组合化学库
JPH10500951A (ja) * 1994-05-23 1998-01-27 スミスクライン・ビーチャム・コーポレイション コードされた組合せライブラリー
US6210900B1 (en) * 1995-05-23 2001-04-03 Smithkline Beecham Corporation Method of encoding a series of combinatorial libraries and developing structure activity relationships
DE69638321D1 (de) 1995-10-11 2011-03-03 Luminex Corp Gleichzeitige mehrfachanalyse klinischer proben
US5981180A (en) 1995-10-11 1999-11-09 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
NO308755B1 (no) * 1996-12-20 2000-10-23 Iystein Fodstad FremgangsmÕte til karakterisering av unormale celler, anvendelse og sett for utførelse av fremgangsmÕten
US6023540A (en) 1997-03-14 2000-02-08 Trustees Of Tufts College Fiber optic sensor with encoded microspheres
US5834203A (en) 1997-08-25 1998-11-10 Applied Spectral Imaging Method for classification of pixels into groups according to their spectra using a plurality of wide band filters and hardwire therefore
AU1080999A (en) 1997-10-14 1999-05-03 Luminex Corporation Precision fluorescently dyed particles and methods of making and using same
CA2335951C (en) * 1998-06-24 2013-07-30 Mark S. Chee Decoding of array sensors with microspheres

Also Published As

Publication number Publication date
US20010044116A1 (en) 2001-11-22
US20010031464A1 (en) 2001-10-18
IL199919A (en) 2011-05-31
DE69940639D1 (de) 2009-05-07
US6492125B2 (en) 2002-12-10
US6642062B2 (en) 2003-11-04
EP1942346A1 (de) 2008-07-09
IL141759A (en) 2010-05-31
US20040072233A1 (en) 2004-04-15

Similar Documents

Publication Publication Date Title
ATE426814T1 (de) Markierungsmittel mit einer vielzahl von farbtínen
CA2342767A1 (en) Multihued labels
DE60131194D1 (de) Sequenzbestimmung in echtzeit
DE69720763D1 (de) Sätze von, mit fluoreszierenden energieübertragungsverbindungen, markierten primern und deren verwendung in mehrkomponentenanalyse
DE59808440D1 (de) Organische lichtemittierende Diode mit Terbiumkomplex
ATE146503T1 (de) Methode zur kennzeignung von thermoplastischen marerialien mit nahinfrarot-fluorophoren
DE69530286D1 (de) Mit energieübertragungsvermittelnden verbindungen markierte proben
DE69937946D1 (de) Hashen von objekten mit inkrementalen änderungen
ATA24393A (de) Reagenzlösung zur stabilisierung der lumineszenz bei der luciferasemessung
DE69817165D1 (de) Sulfonierte xanthenderivate
DE60323788D1 (de) Weisse organische Leuchtdiode mit einer dünnen Rubren-Schicht
DE69229801D1 (de) Testmatrix zur durchführung von assays
DE69012892D1 (de) Organische elektrolumineszente Vorrichtung.
ATE287336T1 (de) Farbverschiebungsfolie mit fluoreszierenden und nicht-fluoreszierenden farbmitteln in musterform
DE69905206T2 (de) Organische,elektrolumineszierente Bildanzeigetafel mit einer Vielzahl von Sperren
BR9004591A (pt) Processo de produzir uma geograde a respectiva geograde,e processo de reforcar a resistencia do solo
AR001584A1 (es) Una composicion para marcadores incoloros de petroleo
FR2873128B1 (fr) Procede de marquage d'un materiau et materiau ainsi marque
ATE333522T1 (de) Verfahren zur bestimmung von mehrere analyten
DE69841569D1 (de) Organische elektrolumineszente Vorrichtung mit verbesserter Langzeitstabilität
DE69001008D1 (de) Anlage zum anbringen von fahrbahnoberflaechen-markierelementen.
DE602006000722D1 (de) Bauplatte, die eine Beleuchtung enthält
ID30073A (id) Metode untuk menyambung, menandai dan memodifikasi secara struktural monofilamen-monofilamen
DE60219791D1 (de) Beleuchtetes strassenschild
DE50104118D1 (de) Signierelement zum Kennzeichen von Holz, insbesondere von Baumstämmen

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties