ATE427957T1 - Echinocandinverfahren - Google Patents

Echinocandinverfahren

Info

Publication number
ATE427957T1
ATE427957T1 AT02725776T AT02725776T ATE427957T1 AT E427957 T1 ATE427957 T1 AT E427957T1 AT 02725776 T AT02725776 T AT 02725776T AT 02725776 T AT02725776 T AT 02725776T AT E427957 T1 ATE427957 T1 AT E427957T1
Authority
AT
Austria
Prior art keywords
echinocandin
echinocandin process
Prior art date
Application number
AT02725776T
Other languages
English (en)
Inventor
Kevin Belyk
William Leonard
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE427957T1 publication Critical patent/ATE427957T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT02725776T 2001-04-12 2002-04-08 Echinocandinverfahren ATE427957T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28329701P 2001-04-12 2001-04-12

Publications (1)

Publication Number Publication Date
ATE427957T1 true ATE427957T1 (de) 2009-04-15

Family

ID=23085377

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02725776T ATE427957T1 (de) 2001-04-12 2002-04-08 Echinocandinverfahren

Country Status (14)

Country Link
EP (1) EP1392722B1 (de)
JP (1) JP4272432B2 (de)
AR (1) AR035808A1 (de)
AT (1) ATE427957T1 (de)
AU (1) AU2002256323B2 (de)
CA (1) CA2443702C (de)
CY (1) CY1109207T1 (de)
DE (1) DE60231872D1 (de)
DK (1) DK1392722T3 (de)
ES (1) ES2322243T3 (de)
PT (1) PT1392722E (de)
SI (1) SI1392722T1 (de)
TW (1) TWI324610B (de)
WO (1) WO2002083713A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1785432A1 (de) 2005-11-15 2007-05-16 Sandoz AG Verfahren und Zwischenprodukte zur Synthese des Caspofungins
US20120190815A1 (en) * 2009-08-06 2012-07-26 Tianhui Xu Azacyclohexapeptide or its pharmaceutical acceptable salt, preparing method and use thereof
CN102947327B (zh) 2010-03-29 2017-06-13 中化帝斯曼制药有限公司荷兰公司 卡泊芬净中间体的纯化
CN101792486A (zh) * 2010-04-12 2010-08-04 浙江海正药业股份有限公司 一种合成醋酸卡泊芬净的方法
CN102367267B (zh) 2010-11-10 2013-09-04 上海天伟生物制药有限公司 一种卡泊芬净的制备方法
CN102367269B (zh) 2010-11-10 2013-11-06 上海天伟生物制药有限公司 一种卡泊芬净类似物及其制备方法和用途
CN102367268B (zh) * 2010-11-10 2013-11-06 上海天伟生物制药有限公司 一种卡泊芬净类似物及其用途
US20140005355A1 (en) * 2011-01-03 2014-01-02 Biocon Limited Process for preparation of caspofungin acetate and intermediates
CN102746384B (zh) 2011-04-22 2016-01-20 上海天伟生物制药有限公司 一种高纯度的卡泊芬净或其盐及其制备方法和用途
AU2012248013B2 (en) * 2011-04-28 2016-07-14 Unitris Biopharma Co., Ltd Intermediate for synthesizing caspofungin and preparation method therefor
CN102627689B (zh) * 2012-03-30 2014-08-06 上海天伟生物制药有限公司 一种环肽类化合物的水合物及其制备方法和用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5939384A (en) * 1991-10-01 1999-08-17 Merck & Co., Inc. Cyclohexapeptidyl propanolamine compounds
US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
US5552521A (en) * 1995-02-10 1996-09-03 Merck & Co., Inc. Process for preparing certain aza cyclohexapeptides
US5936062A (en) * 1997-06-12 1999-08-10 Merck & Co., Inc. Process for preparing certain aza cyclohexapeptides
CA2340647A1 (en) * 1998-08-28 2000-03-09 Eli Lilly And Company Reversible boronate complexes of 1,2-cis-diol cyclic-peptides

Also Published As

Publication number Publication date
DE60231872D1 (en) 2009-05-20
WO2002083713A3 (en) 2003-02-27
JP4272432B2 (ja) 2009-06-03
WO2002083713A2 (en) 2002-10-24
DK1392722T3 (da) 2009-08-10
EP1392722B1 (de) 2009-04-08
JP2004529146A (ja) 2004-09-24
EP1392722A4 (de) 2007-04-18
TWI324610B (en) 2010-05-11
AR035808A1 (es) 2004-07-14
CY1109207T1 (el) 2014-07-02
CA2443702A1 (en) 2002-10-24
ES2322243T3 (es) 2009-06-18
EP1392722A2 (de) 2004-03-03
PT1392722E (pt) 2009-05-25
AU2002256323B2 (en) 2007-05-24
SI1392722T1 (sl) 2009-10-31
CA2443702C (en) 2012-09-18

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