ATE428406T1 - Bioadhäsive zusammensetzung - Google Patents

Bioadhäsive zusammensetzung

Info

Publication number
ATE428406T1
ATE428406T1 AT01909120T AT01909120T ATE428406T1 AT E428406 T1 ATE428406 T1 AT E428406T1 AT 01909120 T AT01909120 T AT 01909120T AT 01909120 T AT01909120 T AT 01909120T AT E428406 T1 ATE428406 T1 AT E428406T1
Authority
AT
Austria
Prior art keywords
bioadhesive composition
solid
solution
polymer mixture
polymer
Prior art date
Application number
AT01909120T
Other languages
English (en)
Inventor
Paul Foreman
Paul Richardson
John Tsai
Jean-Paul Remon
Jody Voorspoels
Dieter Ameye
Catherine Callens
Original Assignee
Nat Starch Chem Invest
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Starch Chem Invest filed Critical Nat Starch Chem Invest
Application granted granted Critical
Publication of ATE428406T1 publication Critical patent/ATE428406T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/24Crosslinking, e.g. vulcanising, of macromolecules
    • C08J3/246Intercrosslinking of at least two polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2300/00Characterised by the use of unspecified polymers
    • C08J2300/10Polymers characterised by the presence of specified groups, e.g. terminal or pendant functional groups
    • C08J2300/104Polymers characterised by the presence of specified groups, e.g. terminal or pendant functional groups containing oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Materials For Medical Uses (AREA)
AT01909120T 2000-02-11 2001-02-08 Bioadhäsive zusammensetzung ATE428406T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/502,585 US6284235B1 (en) 2000-02-11 2000-02-11 Bioadhesive composition
PCT/US2001/004418 WO2001058430A1 (en) 2000-02-11 2001-02-08 Bioadhesive composition

Publications (1)

Publication Number Publication Date
ATE428406T1 true ATE428406T1 (de) 2009-05-15

Family

ID=23998471

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01909120T ATE428406T1 (de) 2000-02-11 2001-02-08 Bioadhäsive zusammensetzung

Country Status (6)

Country Link
US (2) US6284235B1 (de)
EP (1) EP1257258B1 (de)
AT (1) ATE428406T1 (de)
AU (1) AU2001236905A1 (de)
DE (1) DE60138362D1 (de)
WO (1) WO2001058430A1 (de)

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US6541014B2 (en) 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
ES2323264T3 (es) * 2001-08-01 2009-07-10 Novartis Ag Composicion para enmascaramiento del sabor.
US7846478B2 (en) * 2002-01-31 2010-12-07 Henkel Ag & Co. Kgaa Bioadhesive composition
JP2006528185A (ja) 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
AU2004258949B2 (en) 2003-07-21 2011-02-10 Shionogi, Inc. Antibiotic product, use and formulation thereof
AU2004258953B2 (en) 2003-07-21 2011-02-10 Shionogi, Inc. Antibiotic product, use and formulation thereof
CA2535177A1 (en) 2003-08-11 2005-02-24 Advancis Pharmaceutical Corporation Robust pellet
US8062672B2 (en) 2003-08-12 2011-11-22 Shionogi Inc. Antibiotic product, use and formulation thereof
AU2004270170B2 (en) 2003-08-29 2011-01-27 Shionogi, Inc. Antibiotic product, use and formulation thereof
CA2538064C (en) 2003-09-15 2013-12-17 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
DE10358748A1 (de) * 2003-12-12 2005-07-14 Lts Lohmann Therapie-Systeme Ag Darreichungsform basierend auf vernetzten hydrophilen Polymeren
US20050249799A1 (en) * 2004-03-03 2005-11-10 Spherics, Inc. Polymeric drug delivery system for hydrophobic drugs
US20050276771A1 (en) * 2004-06-10 2005-12-15 Lewis Farsedakis Color-giving lip covering, color for lips, peelable cosmetics, and other cosmetics
CA2572292A1 (en) 2004-07-02 2006-02-09 Advancis Pharmaceutical Corporation Tablet for pulsed delivery
WO2006021054A1 (en) * 2004-08-27 2006-03-02 Newsouth Innovations Pty Limited Bioadhesive for tissue repair
WO2006026504A2 (en) * 2004-08-27 2006-03-09 Spherics, Inc. Mucoadhesive oral formulations of high permeability, high solubility drugs
US20060045865A1 (en) * 2004-08-27 2006-03-02 Spherics, Inc. Controlled regional oral delivery
US9707252B2 (en) * 2005-02-09 2017-07-18 Covidien Lp Synthetic sealants
US20070026052A1 (en) * 2005-07-28 2007-02-01 Baggett Richard W Hemostatic material
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US20070190013A1 (en) * 2006-02-13 2007-08-16 Yeli Zhang Film and film-forming compositions
US20100028407A1 (en) * 2006-04-27 2010-02-04 University Of Louisville Research Foundation, Inc. Layered bio-adhesive compositions and uses thereof
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
ES2667945T3 (es) 2007-10-08 2018-05-16 Aurinia Pharmaceuticals Inc. Composiciones oftálmicas que comprenden inhibidores de calcineurina o Inhibidores de mTOR
EP2440185B1 (de) 2009-06-09 2015-04-08 Aurinia Pharmaceuticals Inc. Topische arzneimittelabgabesysteme zur ophthalmischen verwendung
WO2011026111A1 (en) 2009-08-31 2011-03-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Oral delivery of a vaccine to the large intestine to induce mucosal immunity
US9549842B2 (en) 2011-02-04 2017-01-24 Joseph E. Kovarik Buccal bioadhesive strip and method of treating snoring and sleep apnea
US8701671B2 (en) 2011-02-04 2014-04-22 Joseph E. Kovarik Non-surgical method and system for reducing snoring
US11998479B2 (en) 2011-02-04 2024-06-04 Seed Health, Inc. Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure
US12257272B2 (en) 2015-12-24 2025-03-25 Seed Health, Inc. Method and system for reducing the likelihood of developing depression in an individual
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
US11357722B2 (en) 2011-02-04 2022-06-14 Seed Health, Inc. Method and system for preventing sore throat in humans
US12279989B2 (en) 2011-02-04 2025-04-22 Seed Health, Inc. Method and system for increasing beneficial bacteria and decreasing pathogenic bacteria in the oral cavity
US11951140B2 (en) 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
US12533312B2 (en) 2011-02-04 2026-01-27 Seed Health, Inc. Method and system for preventing sore throat in humans
US11951139B2 (en) 2015-11-30 2024-04-09 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US10085938B2 (en) 2011-02-04 2018-10-02 Joseph E. Kovarik Method and system for preventing sore throat in humans
US8999376B2 (en) 2012-02-03 2015-04-07 Xcede Technologies, Inc. Tissue patch
US11998574B2 (en) 2013-12-20 2024-06-04 Seed Health, Inc. Method and system for modulating an individual's skin microbiome
US11980643B2 (en) 2013-12-20 2024-05-14 Seed Health, Inc. Method and system to modify an individual's gut-brain axis to provide neurocognitive protection
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US11833177B2 (en) 2013-12-20 2023-12-05 Seed Health, Inc. Probiotic to enhance an individual's skin microbiome
US12329783B2 (en) 2013-12-20 2025-06-17 Seed Health, Inc. Method and system to improve the health of a person's skin microbiome
US12005085B2 (en) 2013-12-20 2024-06-11 Seed Health, Inc. Probiotic method and composition for maintaining a healthy vaginal microbiome
US11839632B2 (en) 2013-12-20 2023-12-12 Seed Health, Inc. Topical application of CRISPR-modified bacteria to treat acne vulgaris
US11969445B2 (en) 2013-12-20 2024-04-30 Seed Health, Inc. Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH
US12246043B2 (en) 2013-12-20 2025-03-11 Seed Health, Inc. Topical application to treat acne vulgaris
DE102014012238A1 (de) 2014-08-21 2016-02-25 Johns Manville Europe Gmbh Binderverfestigtes, textiles Flächengebilde, Verfahren zu dessen Herstellung und dessen Verwendung
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EP3982917A1 (de) 2019-06-14 2022-04-20 The Procter & Gamble Company Verweil-mundpflegezusammensetzungen
WO2020248239A1 (en) 2019-06-14 2020-12-17 The Procter & Gamble Company Leave-on oral care compositions
MX2021015126A (es) 2019-06-14 2022-01-24 Procter & Gamble Composiciones para el cuidado bucal para usar y no enjuagar.
JP2022538521A (ja) 2019-06-14 2022-09-05 ザ プロクター アンド ギャンブル カンパニー 洗い流さない口腔ケア組成物
WO2020248232A1 (en) * 2019-06-14 2020-12-17 The Procter & Gamble Company Leave-on oral care compositions

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US4915948A (en) * 1987-08-31 1990-04-10 Warner-Lambert Company Tablets having improved bioadhesion to mucous membranes
CA2018471A1 (en) * 1989-07-28 1991-01-28 Ian W. Kellaway Mucoadhesive hydrogels delivery system
MC2204A1 (fr) * 1989-10-31 1992-11-26 Columbia Lab Inc Composition et methode d'humidification de tissus
EP0451433B1 (de) * 1990-04-12 1996-10-23 Janssen Pharmaceutica N.V. Zusammensetzung zur Anwendung eines Arzneimittels, bestehend aus einem Bioadhäsiven Trägerstoff mit verzögerter Freisetzung
US5942253A (en) * 1995-10-12 1999-08-24 Immunex Corporation Prolonged release of GM-CSF
WO1998022097A2 (en) * 1996-11-20 1998-05-28 Bio Advances, Llc Controlled release matrix composition using polar polymer or monomer and poly(acrylic acid) blend
US5840329A (en) * 1997-05-15 1998-11-24 Bioadvances Llc Pulsatile drug delivery system
US5895804A (en) 1997-10-27 1999-04-20 National Starch And Chemical Investment Holding Corporation Thermosetting polysaccharides
WO2000047644A1 (en) 1999-02-12 2000-08-17 Universiteit Gent A biocompatible adhesive system and a bioadhesive drug delivery system with controllable release
US6284235B1 (en) * 2000-02-11 2001-09-04 National Starch And Chemical Company Investment Holding Corporation Bioadhesive composition

Also Published As

Publication number Publication date
DE60138362D1 (de) 2009-05-28
WO2001058430A1 (en) 2001-08-16
AU2001236905A1 (en) 2001-08-20
US6284235B1 (en) 2001-09-04
US6824792B2 (en) 2004-11-30
EP1257258B1 (de) 2009-04-15
EP1257258A1 (de) 2002-11-20
US20020028241A1 (en) 2002-03-07

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties