ATE428492T1 - Verfahren und vorrichtung zur dosierung und durchmischung kleiner flüssigkeitsmengen, apparat und verwendung - Google Patents

Verfahren und vorrichtung zur dosierung und durchmischung kleiner flüssigkeitsmengen, apparat und verwendung

Info

Publication number
ATE428492T1
ATE428492T1 AT05820542T AT05820542T ATE428492T1 AT E428492 T1 ATE428492 T1 AT E428492T1 AT 05820542 T AT05820542 T AT 05820542T AT 05820542 T AT05820542 T AT 05820542T AT E428492 T1 ATE428492 T1 AT E428492T1
Authority
AT
Austria
Prior art keywords
liquid
reservoir
dosing
small quantities
reservoirs
Prior art date
Application number
AT05820542T
Other languages
English (en)
Inventor
Christoph Gauer
Original Assignee
Advalytix Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advalytix Ag filed Critical Advalytix Ag
Application granted granted Critical
Publication of ATE428492T1 publication Critical patent/ATE428492T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/80—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations
    • B01F31/86—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations with vibration of the receptacle or part of it
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/80—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations
    • B01F31/87—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations transmitting the vibratory energy by means of a fluid, e.g. by means of air shock waves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/089—Virtual walls for guiding liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0433—Moving fluids with specific forces or mechanical means specific forces vibrational forces
    • B01L2400/0436—Moving fluids with specific forces or mechanical means specific forces vibrational forces acoustic forces, e.g. surface acoustic waves [SAW]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0493—Specific techniques used
    • B01L2400/0496—Travelling waves, e.g. in combination with electrical or acoustic forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
AT05820542T 2005-01-05 2005-12-16 Verfahren und vorrichtung zur dosierung und durchmischung kleiner flüssigkeitsmengen, apparat und verwendung ATE428492T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005000835A DE102005000835B3 (de) 2005-01-05 2005-01-05 Verfahren und Vorrichtung zur Dosierung kleiner Flüssigkeitsmengen
PCT/EP2005/013598 WO2006072384A1 (de) 2005-01-05 2005-12-16 Verfahren und vorrichtung zur dosierung und durchmischung kleiner flüssigkeitsmengen

Publications (1)

Publication Number Publication Date
ATE428492T1 true ATE428492T1 (de) 2009-05-15

Family

ID=35911180

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05820542T ATE428492T1 (de) 2005-01-05 2005-12-16 Verfahren und vorrichtung zur dosierung und durchmischung kleiner flüssigkeitsmengen, apparat und verwendung

Country Status (6)

Country Link
US (1) US8186869B2 (de)
EP (1) EP1843833B1 (de)
JP (1) JP4956439B2 (de)
AT (1) ATE428492T1 (de)
DE (2) DE102005000835B3 (de)
WO (1) WO2006072384A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5112880B2 (ja) * 2005-01-05 2013-01-09 ベックマン コールター， インコーポレイテッド 少量の液体を調薬及び混合するための方法及び装置
JP2008100182A (ja) * 2006-10-20 2008-05-01 Hitachi Plant Technologies Ltd 乳化装置および微粒子製造装置
JP4852399B2 (ja) * 2006-11-22 2012-01-11 富士フイルム株式会社 二液合流装置
DE102007020243B4 (de) * 2007-04-24 2009-02-26 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Akustische Misch- und/oder Fördervorrichtung und Probenaufbereitungschip mit einer solchen
JP5159197B2 (ja) * 2007-07-25 2013-03-06 キヤノン株式会社 液体制御装置
JP5116112B2 (ja) * 2009-02-19 2013-01-09 シャープ株式会社 流体混合装置及び流体混合方法
EP2706361A1 (de) * 2012-09-06 2014-03-12 F. Hoffmann-La Roche AG System zur Ausgabe einer Probe in eine Pufferflüssigkeit
CN111545439A (zh) * 2020-06-29 2020-08-18 海积(北京)科技有限公司 多用途大功率高频声场耦合传振器
EP4717442A1 (de) * 2024-09-30 2026-04-01 Technische Universität München, in Vertretung des Freistaats Bayern Vorrichtung und verfahren zur strömungsformung

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US4955723A (en) * 1990-01-16 1990-09-11 Schneider John R Slurry mixing apparatus with dry powder conveyer
AU4047493A (en) * 1992-04-02 1993-11-08 Abaxis, Inc. Analytical rotor with dye mixing chamber
US5639423A (en) * 1992-08-31 1997-06-17 The Regents Of The University Of Calfornia Microfabricated reactor
US6010316A (en) * 1996-01-16 2000-01-04 The Board Of Trustees Of The Leland Stanford Junior University Acoustic micropump
US6012902A (en) * 1997-09-25 2000-01-11 Caliper Technologies Corp. Micropump
JPH11347392A (ja) * 1998-06-11 1999-12-21 Hitachi Ltd 攪拌装置
US6086243A (en) * 1998-10-01 2000-07-11 Sandia Corporation Electrokinetic micro-fluid mixer
US6601613B2 (en) * 1998-10-13 2003-08-05 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
US6210128B1 (en) * 1999-04-16 2001-04-03 The United States Of America As Represented By The Secretary Of The Navy Fluidic drive for miniature acoustic fluidic pumps and mixers
US7601270B1 (en) * 1999-06-28 2009-10-13 California Institute Of Technology Microfabricated elastomeric valve and pump systems
US7381241B2 (en) * 1999-11-24 2008-06-03 Impulse Devices, Inc. Degassing procedure for a cavitation chamber
JP2001212469A (ja) * 2000-02-01 2001-08-07 Seiko Epson Corp ピペット及びそれを用いた反応方法と混合方法
US6777245B2 (en) 2000-06-09 2004-08-17 Advalytix Ag Process for manipulation of small quantities of matter
DE10055318A1 (de) * 2000-06-09 2001-12-20 Advalytix Ag Vorrichtung und Verfahren zum Materietransport kleiner Materiemengen
JP2002008753A (ja) * 2000-06-16 2002-01-11 Matsushita Electric Works Ltd コネクタ
DE10041823C2 (de) * 2000-08-25 2002-12-19 Inst Mikrotechnik Mainz Gmbh Verfahren und statischer Mikrovermischer zum Mischen mindestens zweier Fluide
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DE10103954B4 (de) * 2001-01-30 2005-10-06 Advalytix Ag Verfahren zur Analyse von Makromolekülen
US6576459B2 (en) 2001-03-23 2003-06-10 The Regents Of The University Of California Sample preparation and detection device for infectious agents
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DE10142789C1 (de) * 2001-08-31 2003-05-28 Advalytix Ag Bewegungselement für kleine Flüssigkeitsmengen
JP3749991B2 (ja) 2001-10-18 2006-03-01 アイダエンジニアリング株式会社 微量液体秤取構造及び該構造を有するマイクロチップ
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US6811385B2 (en) 2002-10-31 2004-11-02 Hewlett-Packard Development Company, L.P. Acoustic micro-pump
DE10325313B3 (de) 2003-02-27 2004-07-29 Advalytix Ag Verfahren und Vorrichtung zur Erzeugung von Bewegung in einem dünnen Flüssigkeitsfilm
DE10325307B3 (de) * 2003-02-27 2004-07-15 Advalytix Ag Verfahren und Vorrichtung zur Durchmischung kleiner Flüssigkeitsmengen in Mikrokavitäten
WO2004076046A1 (de) 2003-02-27 2004-09-10 Advalytix Ag Verfahren und vorrichtung zur durchmischung kleiner flüssigkeitsmengen in mikrokavitäten
US7347617B2 (en) * 2003-08-19 2008-03-25 Siemens Healthcare Diagnostics Inc. Mixing in microfluidic devices
JP4341372B2 (ja) * 2003-10-30 2009-10-07 コニカミノルタホールディングス株式会社 液体の混合方法および混合装置ならびに混合システム
JP5112880B2 (ja) * 2005-01-05 2013-01-09 ベックマン コールター， インコーポレイテッド 少量の液体を調薬及び混合するための方法及び装置
JP5196304B2 (ja) * 2008-07-29 2013-05-15 大日本印刷株式会社 エマルジョン形成用マイクロチップおよびその製造方法

Also Published As

Publication number Publication date
US20080186799A1 (en) 2008-08-07
DE502005007112D1 (de) 2009-05-28
US8186869B2 (en) 2012-05-29
JP4956439B2 (ja) 2012-06-20
EP1843833A1 (de) 2007-10-17
JP2008527338A (ja) 2008-07-24
EP1843833B1 (de) 2009-04-15
WO2006072384A1 (de) 2006-07-13
DE102005000835B3 (de) 2006-09-07

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Legal Events

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