ATE428925T1 - Automatische probenvorbereitungsverfahren und - vorrichtungen - Google Patents

Automatische probenvorbereitungsverfahren und - vorrichtungen

Info

Publication number
ATE428925T1
ATE428925T1 AT02789816T AT02789816T ATE428925T1 AT E428925 T1 ATE428925 T1 AT E428925T1 AT 02789816 T AT02789816 T AT 02789816T AT 02789816 T AT02789816 T AT 02789816T AT E428925 T1 ATE428925 T1 AT E428925T1
Authority
AT
Austria
Prior art keywords
sample preparation
preparation methods
automatic sample
sample
concentration
Prior art date
Application number
AT02789816T
Other languages
English (en)
Inventor
Duncan Whitney
Original Assignee
Exact Sciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exact Sciences Corp filed Critical Exact Sciences Corp
Application granted granted Critical
Publication of ATE428925T1 publication Critical patent/ATE428925T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38—Diluting, dispersing or mixing samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00158—Elements containing microarrays, i.e. "biochip"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1032—Dilution or aliquotting

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT02789816T 2001-11-20 2002-11-20 Automatische probenvorbereitungsverfahren und - vorrichtungen ATE428925T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33165401P 2001-11-20 2001-11-20
PCT/US2002/037452 WO2003044217A2 (en) 2001-11-20 2002-11-20 Automated sample preparation methods and devices

Publications (1)

Publication Number Publication Date
ATE428925T1 true ATE428925T1 (de) 2009-05-15

Family

ID=23294819

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02789816T ATE428925T1 (de) 2001-11-20 2002-11-20 Automatische probenvorbereitungsverfahren und - vorrichtungen

Country Status (8)

Country Link
US (1) US20030204331A1 (de)
EP (1) EP1456648B8 (de)
JP (1) JP2005509871A (de)
AT (1) ATE428925T1 (de)
AU (1) AU2002352858A1 (de)
CA (1) CA2467248A1 (de)
DE (1) DE60232013D1 (de)
WO (1) WO2003044217A2 (de)

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US6818404B2 (en) 1997-10-23 2004-11-16 Exact Sciences Corporation Methods for detecting hypermethylated nucleic acid in heterogeneous biological samples
US7569342B2 (en) 1997-12-10 2009-08-04 Sierra Molecular Corp. Removal of molecular assay interferences
US6964846B1 (en) 1999-04-09 2005-11-15 Exact Sciences Corporation Methods for detecting nucleic acids indicative of cancer
EP1356094B1 (de) * 2000-06-26 2010-01-13 Nugen Technologies, Inc. Methoden und zusammensetzungen zur auf transkription basierenden vervielfältigung von nukleinsäuren
US7846733B2 (en) 2000-06-26 2010-12-07 Nugen Technologies, Inc. Methods and compositions for transcription-based nucleic acid amplification
EP1427847B1 (de) 2000-12-13 2010-07-28 Nugen Technologies, Inc. Methoden und zusammensetzungen zur generierung einer vielzahl von kopien von nukleinsäuresequenzen und methoden zur detektion derselben
MXPA02012739A (es) 2001-03-09 2004-04-20 Nugen Technologies Inc Metodos y composiciones para amplificacion de secuencias de arn.
JP2006523465A (ja) 2003-04-14 2006-10-19 ニューゲン テクノロジーズ， インコーポレイテッド ランダムにプライミングされる複合プライマーを用いる大規模増幅
US7256888B2 (en) 2003-11-07 2007-08-14 Cardial Health 303, Inc. Fluid verification system and method for infusions
US7704730B2 (en) 2004-10-14 2010-04-27 Meso Scale Technologies, Llc Multiplexed assay methods
WO2006047787A2 (en) 2004-10-27 2006-05-04 Exact Sciences Corporation Method for monitoring disease progression or recurrence
US9777314B2 (en) 2005-04-21 2017-10-03 Esoterix Genetic Laboratories, Llc Analysis of heterogeneous nucleic acid samples
EP2703499A1 (de) 2005-06-02 2014-03-05 Fluidigm Corporation Analyse unter Verwendung einer mikrofluidischen Aufteilungsvorrichtung zur Bereitstellung von Einzelzellproben
EP1929046B1 (de) 2005-09-07 2012-07-11 Nugen Technologies, Inc. Verbessertes nukleinsäureamplifikationsverfahren
WO2007092473A2 (en) 2006-02-02 2007-08-16 The Board Of Trustees Of The Leland Stanford Junior University Non-invasive fetal genetic screening by digital analysis
CN103789434A (zh) * 2006-04-10 2014-05-14 杜克大学 检测遗传突变的方法
US8137912B2 (en) 2006-06-14 2012-03-20 The General Hospital Corporation Methods for the diagnosis of fetal abnormalities
US8372584B2 (en) 2006-06-14 2013-02-12 The General Hospital Corporation Rare cell analysis using sample splitting and DNA tags
EP2029779A4 (de) 2006-06-14 2010-01-20 Living Microsystems Inc Verwendung hoch paralleler snp-genotypisierung zur fötalen diagnose
US20080050739A1 (en) 2006-06-14 2008-02-28 Roland Stoughton Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
US7901624B2 (en) 2006-09-26 2011-03-08 Becton, Dickinson And Company Device for automatically adjusting the bacterial inoculum level of a sample
US9114398B2 (en) * 2006-11-29 2015-08-25 Canon U.S. Life Sciences, Inc. Device and method for digital multiplex PCR assays
US12054776B2 (en) 2007-07-23 2024-08-06 The Chinese University Of Hong Kong Diagnosing fetal chromosomal aneuploidy using massively parallel genomic sequencing
US12180549B2 (en) 2007-07-23 2024-12-31 The Chinese University Of Hong Kong Diagnosing fetal chromosomal aneuploidy using genomic sequencing
US8034568B2 (en) 2008-02-12 2011-10-11 Nugen Technologies, Inc. Isothermal nucleic acid amplification methods and compositions
US7846666B2 (en) * 2008-03-21 2010-12-07 Nugen Technologies, Inc. Methods of RNA amplification in the presence of DNA
WO2010033578A2 (en) 2008-09-20 2010-03-25 The Board Of Trustees Of The Leland Stanford Junior University Noninvasive diagnosis of fetal aneuploidy by sequencing
CN104471077B (zh) 2012-05-21 2017-05-24 富鲁达公司 颗粒群的单颗粒分析
US10364467B2 (en) 2015-01-13 2019-07-30 The Chinese University Of Hong Kong Using size and number aberrations in plasma DNA for detecting cancer
EP3261762B1 (de) 2015-02-27 2021-09-01 Mastaplex Limited Probengefäss, probenbehälter und verfahren zur verwendung
GB201516992D0 (en) 2015-09-25 2015-11-11 Ge Healthcare Bio Sciences Ab Method and system for evaluation of an interaction between an analyte and a ligand using a biosensor
JP7254036B2 (ja) * 2017-06-26 2023-04-07 バイオ―ラッド ヨーロッパ ゲーエムベーハー その場段階希釈法
KR102279539B1 (ko) 2017-06-29 2021-07-20 주식회사 씨젠 검출용 조성물 준비 장치의 제어 방법 및 기기
JP2019066254A (ja) * 2017-09-29 2019-04-25 株式会社安川電機 分注システム及び分注方法
CN114364988A (zh) * 2019-08-05 2022-04-15 贝克曼库尔特有限公司 使用自动化分析仪进行机载稀释的方法
CN112877178B (zh) * 2021-03-10 2022-07-29 太原科技大学 一种放线菌高效分离培养装置

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US6033854A (en) * 1991-12-16 2000-03-07 Biotronics Corporation Quantitative PCR using blocking oligonucleotides
US5976798A (en) * 1994-03-30 1999-11-02 Mitokor Methods for detecting mitochondrial mutations diagnostic for Alzheimer's disease and methods for determining heteroplasmy of mitochondrial nucleic acid
US6586193B2 (en) * 1996-04-25 2003-07-01 Genicon Sciences Corporation Analyte assay using particulate labels
US6235471B1 (en) * 1997-04-04 2001-05-22 Caliper Technologies Corp. Closed-loop biochemical analyzers
US6391622B1 (en) * 1997-04-04 2002-05-21 Caliper Technologies Corp. Closed-loop biochemical analyzers
NZ516848A (en) * 1997-06-20 2004-03-26 Ciphergen Biosystems Inc Retentate chromatography apparatus with applications in biology and medicine
AU3454699A (en) * 1998-03-30 1999-10-18 Friedrich Srienc A flow injection flow cytometry system for on-line monitoring of bioreactors andmethod for monitoring
KR20010034814A (ko) * 1998-04-23 2001-04-25 제넨테크, 인크. 유전자 발현의 정량적 분석
US6440706B1 (en) * 1999-08-02 2002-08-27 Johns Hopkins University Digital amplification
DE10045521A1 (de) * 2000-03-31 2001-10-04 Roche Diagnostics Gmbh Nukleinsäureamplifikationen

Also Published As

Publication number Publication date
CA2467248A1 (en) 2003-05-30
WO2003044217A2 (en) 2003-05-30
WO2003044217A3 (en) 2003-10-23
JP2005509871A (ja) 2005-04-14
EP1456648A4 (de) 2005-06-29
US20030204331A1 (en) 2003-10-30
AU2002352858A1 (en) 2003-06-10
EP1456648B1 (de) 2009-04-15
EP1456648A2 (de) 2004-09-15
DE60232013D1 (de) 2009-05-28
EP1456648B8 (de) 2009-07-08

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