ATE429447T1 - Aufreinigung von her-2-varianten - Google Patents

Aufreinigung von her-2-varianten

Info

Publication number
ATE429447T1
ATE429447T1 AT04738948T AT04738948T ATE429447T1 AT E429447 T1 ATE429447 T1 AT E429447T1 AT 04738948 T AT04738948 T AT 04738948T AT 04738948 T AT04738948 T AT 04738948T AT E429447 T1 ATE429447 T1 AT E429447T1
Authority
AT
Austria
Prior art keywords
purification
provides
chromatography
variant
variants
Prior art date
Application number
AT04738948T
Other languages
English (en)
Inventor
Marie Eskling
Klaus Gregorius Nielsen
Original Assignee
Bn Immunotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bn Immunotherapeutics Inc filed Critical Bn Immunotherapeutics Inc
Application granted granted Critical
Publication of ATE429447T1 publication Critical patent/ATE429447T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A61K39/001103—Receptors for growth factors
    • A61K39/001106—Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ErbB4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT04738948T 2003-06-25 2004-06-24 Aufreinigung von her-2-varianten ATE429447T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48231503P 2003-06-25 2003-06-25
DKPA200300954 2003-06-25
PCT/DK2004/000451 WO2004113377A1 (en) 2003-06-25 2004-06-24 Purification of her-2 variants

Publications (1)

Publication Number Publication Date
ATE429447T1 true ATE429447T1 (de) 2009-05-15

Family

ID=33542436

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04738948T ATE429447T1 (de) 2003-06-25 2004-06-24 Aufreinigung von her-2-varianten

Country Status (12)

Country Link
EP (2) EP1641819B1 (de)
JP (1) JP4579912B2 (de)
AT (1) ATE429447T1 (de)
AU (1) AU2004249362B2 (de)
CA (1) CA2530233C (de)
DE (1) DE602004020769D1 (de)
DK (1) DK1641819T3 (de)
ES (1) ES2325584T3 (de)
MX (1) MXPA05013389A (de)
NO (1) NO20055948L (de)
NZ (1) NZ544017A (de)
WO (1) WO2004113377A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20060033870A (ko) 2003-06-25 2006-04-20 파멕사 에이/에스 Ｈｅｒ-2 변이체의 정제
US20080253993A1 (en) * 2005-03-31 2008-10-16 Pharmexa A/S Immunogenic Egfr Peptides Comprising Foreign T Cell Stimulating Epitope
NZ575388A (en) * 2006-10-06 2012-03-30 Bn Immunotherapeutics Inc Recombinant modified vaccinia ankara encoding a her-2 antigen and a taxane for use in treating cancer
WO2019086463A1 (en) 2017-10-30 2019-05-09 Baxalta GmbH Environmentally compatible detergents for inactivation of lipid-enveloped viruses
JP2023542867A (ja) * 2020-09-11 2023-10-12 グリンプス バイオ， インコーポレイテッド 疾患の検出／診断、病期分類、モニタリング及び処置のための生体外でのプロテアーゼ活性検出

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6080409A (en) * 1995-12-28 2000-06-27 Dendreon Corporation Immunostimulatory method
KR100731820B1 (ko) 1998-10-05 2007-06-25 파멕사 에이/에스 치료적 백신화를 위한 새로운 방법
DE60044665D1 (de) * 1999-01-29 2010-08-26 Corixa Corp Her2/neu fusionsproteine
PL375033A1 (en) * 2002-04-11 2005-11-14 Amgen, Inc. Her-2 receptor tyrosine kinase molecules and uses thereof

Also Published As

Publication number Publication date
JP2007523615A (ja) 2007-08-23
DK1641819T3 (da) 2009-08-03
AU2004249362A1 (en) 2004-12-29
NO20055948L (no) 2005-12-14
EP2090586A1 (de) 2009-08-19
JP4579912B2 (ja) 2010-11-10
CA2530233C (en) 2012-09-11
EP1641819B1 (de) 2009-04-22
AU2004249362B2 (en) 2011-08-25
MXPA05013389A (es) 2006-03-17
CA2530233A1 (en) 2004-12-29
EP1641819A1 (de) 2006-04-05
ES2325584T3 (es) 2009-09-09
WO2004113377A1 (en) 2004-12-29
NZ544017A (en) 2008-04-30
DE602004020769D1 (de) 2009-06-04

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