ATE430167T1 - Humaner rekombinanter antikörper gegen das hepatitis c (hcv) nichtstrukturelles ns3 protein, nukleinsäure und deren verwendungen - Google Patents

Humaner rekombinanter antikörper gegen das hepatitis c (hcv) nichtstrukturelles ns3 protein, nukleinsäure und deren verwendungen

Info

Publication number
ATE430167T1
ATE430167T1 AT02745784T AT02745784T ATE430167T1 AT E430167 T1 ATE430167 T1 AT E430167T1 AT 02745784 T AT02745784 T AT 02745784T AT 02745784 T AT02745784 T AT 02745784T AT E430167 T1 ATE430167 T1 AT E430167T1
Authority
AT
Austria
Prior art keywords
protein
hcv
structural
nucleic acid
antibody against
Prior art date
Application number
AT02745784T
Other languages
English (en)
Inventor
Roberto Burioni
Massimo Clementi
Original Assignee
Gen Antibodies And Biotechnolo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Antibodies And Biotechnolo filed Critical Gen Antibodies And Biotechnolo
Application granted granted Critical
Publication of ATE430167T1 publication Critical patent/ATE430167T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/116—Togaviridae (F); Matonaviridae (F); Flaviviridae (F)
    • C07K16/118—Hepatitis C virus; GB virus C [GBV-C]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/028—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a herpesvirus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT02745784T 2001-06-13 2002-06-11 Humaner rekombinanter antikörper gegen das hepatitis c (hcv) nichtstrukturelles ns3 protein, nukleinsäure und deren verwendungen ATE430167T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2001RM000336A ITRM20010336A1 (it) 2001-06-13 2001-06-13 Anticorpo umano ricombinante diretto contro la proteina non strutturale ns3 del virus dell'epatite c (hcv), acido nucleico codificante e usi
PCT/IT2002/000384 WO2002100900A2 (en) 2001-06-13 2002-06-11 Human recombinant antibody against the hepatitis c (hcv) non structural ns3 protein, nucleic acid and uses thereof

Publications (1)

Publication Number Publication Date
ATE430167T1 true ATE430167T1 (de) 2009-05-15

Family

ID=11455593

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02745784T ATE430167T1 (de) 2001-06-13 2002-06-11 Humaner rekombinanter antikörper gegen das hepatitis c (hcv) nichtstrukturelles ns3 protein, nukleinsäure und deren verwendungen

Country Status (8)

Country Link
US (1) US7314919B2 (de)
EP (1) EP1417233B1 (de)
AT (1) ATE430167T1 (de)
AU (1) AU2002317474A1 (de)
DE (1) DE60232155D1 (de)
DK (1) DK1417233T3 (de)
IT (1) ITRM20010336A1 (de)
WO (1) WO2002100900A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004212641B2 (en) * 2003-02-19 2009-08-06 Merck Millipore Ltd. Composite materials comprising supported porous gels
JP4958773B2 (ja) * 2005-06-02 2012-06-20 松森　　昭 Ｃ型肝炎ウイルス感染の診断、予防および治療方法
EP1951748B1 (de) 2005-11-11 2013-07-24 Vertex Pharmaceuticals, Inc. Varianten des hepatitis-c-virus
US7705138B2 (en) 2005-11-11 2010-04-27 Vertex Pharmaceuticals Incorporated Hepatitis C virus variants
US7858752B2 (en) * 2006-12-05 2010-12-28 Abbott Laboratories Recombinant antibodies against hepatitis C virus and methods of obtaining and using same
JP5642972B2 (ja) 2007-02-21 2014-12-17 ユニバーシティー オブ マサチューセッツＵｎｉｖｅｒｓｉｔｙ ｏｆ Ｍａｓｓａｃｈｕｓｅｔｔｓ Ｃ型肝炎ウイルス（ｈｃｖ）に対するヒト抗体およびその使用
ATE550350T1 (de) 2009-07-10 2012-04-15 Univ Berlin Freie Rock2 und rock3, zwei neue gain-of-function- varianten der cytokininrezeptoren ahk2 und ahk3

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6194140B1 (en) * 1990-04-04 2001-02-27 Chiron Corporation HCV NS3 protein fragments having helicase activity and improved solubility
US6534064B1 (en) * 1999-10-13 2003-03-18 Chiron Corporation Stabilized protein particles for inducing cellular immune responses

Also Published As

Publication number Publication date
WO2002100900A2 (en) 2002-12-19
EP1417233A2 (de) 2004-05-12
US7314919B2 (en) 2008-01-01
US20040214994A1 (en) 2004-10-28
ITRM20010336A0 (it) 2001-06-13
WO2002100900A3 (en) 2004-03-04
AU2002317474A1 (en) 2002-12-23
EP1417233B1 (de) 2009-04-29
DK1417233T3 (da) 2009-06-29
DE60232155D1 (de) 2009-06-10
ITRM20010336A1 (it) 2002-12-13

Similar Documents

Publication Publication Date Title
EP1043399A3 (de) Hepatitis C Virus Zellkultursystem
CY1110437T1 (el) Χρηση παραγωγων καστανοσπερμινης για την θεραπεια της ηπατιτιδας c
ATE286067T1 (de) Hcv hüllproteine partikel : verwendung für therapeutische impfung
WO2006096459A3 (en) Infectious, chimeric hepatitis c virus, methods of producing the same and methods of use thereof
BRPI0516356A (pt) terapia à base de levedura para infecções crÈnicas da hepatite c
ECSP045300A (es) Antígenos virales
FR2855758B1 (fr) Composition comprenant la polyproteine ns3/ns4 et le polypeptide ns5b du vhc, vecteurs d'expression incluant les sequences nucleiques correspondantes et leur utilisation en therapeutique
EP1801209A4 (de) Modifizierte genomische rna des menschlichen hepatitis-c-virus mit autonomer replikationskompetenz
AR041964A1 (es) Vacuna de vhc que comprende un polinucleotido
WO2003004627A3 (fr) Lignees d'hepatomes humains leurs optentions et leurs applications
ATE430167T1 (de) Humaner rekombinanter antikörper gegen das hepatitis c (hcv) nichtstrukturelles ns3 protein, nukleinsäure und deren verwendungen
ATE556136T1 (de) Nichtstrukturelles hcv-fusionsprotein
EP1797112A4 (de) Inhibitoren des hepatitis-c-virus
DE69928064D1 (de) Mimotopen der hypervariabele region des e2 glykoproteins von hcv und deren verwendungen
WO2004014936A3 (fr) Melange de peptides issus des proteines c et ns3 du virus de l'hepatite c et leurs applications.
FI923020A0 (fi) Inte a inte b-sekvenser.
NO20024325D0 (no) Rensede hepatitt C-viruskappeproteiner for diagnostisk og terapeutisk anvendelse
ATE542140T1 (de) Nichtstrukturelle hcv-proteinmutanten und verwendungsmöglichkeiten dafür
WO2003016474A3 (en) Methods and compositions for use in selectively producing a protein in telomerase expressing cells
GB0215617D0 (en) Use of hepatitis C virus (HCV) p7 protein
IT1270941B (it) Peptidi di hcv e loro usi.
WO2004089978A3 (en) Use of hcv proteins
AR031456A1 (es) Proteinas que se unen a hcv y su uso medico diagnostico y de purificacion
EG27024A (en) Natural or recombinant proteins for treatment and diagnosis of hepatitis C virus
HK1067035A (en) Purified hepatitis c virus envelope proteins for diagnostic and therapeutic use

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties