ATE430554T1 - Spontan dispergierbare n-benzoyl staurosporin zusammensetzungen - Google Patents

Spontan dispergierbare n-benzoyl staurosporin zusammensetzungen

Info

Publication number: ATE430554T1
Authority: AT; Austria
Prior art keywords: spontaneously dispersible; benzoyl staurosporine; compositions; staurosporine compositions; benzoyl
Prior art date: 1999-02-16

Application number

AT00909165T

Other languages

English (en)

Inventor

Graham Paul Matthews

Barbara Haeberlin

Original Assignee

Novartis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-02-16

Filing date

2000-02-14

Publication date

2009-05-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10847896&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE430554(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2000-02-14 Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh

2009-05-15 Application granted granted Critical

2009-05-15 Publication of ATE430554T1 publication Critical patent/ATE430554T1/de

Links

BMGQWWVMWDBQGC-IIFHNQTCSA-N midostaurin Chemical compound CN([C@H]1[C@H]([C@]2(C)O[C@@H](N3C4=CC=CC=C4C4=C5C(=O)NCC5=C5C6=CC=CC=C6N2C5=C43)C1)OC)C(=O)C1=CC=CC=C1 BMGQWWVMWDBQGC-IIFHNQTCSA-N 0.000 title 1
239000000203 mixture Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Dispersion Chemistry (AREA)
Heart & Thoracic Surgery (AREA)
Biophysics (AREA)
Cardiology (AREA)
Molecular Biology (AREA)
Urology & Nephrology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Vascular Medicine (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Medicinal Preparation (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT00909165T 1999-02-16 2000-02-14 Spontan dispergierbare n-benzoyl staurosporin zusammensetzungen ATE430554T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9903547.9A GB9903547D0 (en)	1999-02-16	1999-02-16	Organic compounds
PCT/EP2000/001196 WO2000048571A1 (en)	1999-02-16	2000-02-14	Spontaneously dispersible n-benzoyl staurosporine compositions

Publications (1)

Publication Number	Publication Date
ATE430554T1 true ATE430554T1 (de)	2009-05-15

Family

ID=10847896

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00909165T ATE430554T1 (de)	1999-02-16	2000-02-14	Spontan dispergierbare n-benzoyl staurosporin zusammensetzungen

Country Status (34)

Country	Link
US (3)	US20020061873A1 (de)
EP (1)	EP1152750B1 (de)
JP (2)	JP5057610B2 (de)
KR (2)	KR100880859B1 (de)
CN (1)	CN100367930C (de)
AR (2)	AR022589A1 (de)
AT (1)	ATE430554T1 (de)
AU (1)	AU765776B2 (de)
BR (1)	BRPI0008228B8 (de)
CA (1)	CA2362277C (de)
CL (1)	CL2009001682A1 (de)
CZ (1)	CZ303979B6 (de)
DE (1)	DE60042151D1 (de)
DK (1)	DK1152750T3 (de)
EC (1)	ECSP083351A (de)
ES (1)	ES2326783T3 (de)
GB (1)	GB9903547D0 (de)
HK (1)	HK1045807B (de)
HU (1)	HUP0105364A3 (de)
ID (1)	ID30504A (de)
IL (3)	IL144512A0 (de)
MY (1)	MY128362A (de)
NO (1)	NO331232B1 (de)
NZ (1)	NZ513529A (de)
PE (1)	PE20001499A1 (de)
PL (1)	PL198330B1 (de)
PT (1)	PT1152750E (de)
RU (1)	RU2266121C2 (de)
SI (1)	SI1152750T1 (de)
SK (1)	SK286967B6 (de)
TR (1)	TR200102385T2 (de)
TW (1)	TWI240636B (de)
WO (1)	WO2000048571A1 (de)
ZA (1)	ZA200106677B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
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US6200968B1 (en) *	1998-08-06	2001-03-13	Cephalon, Inc.	Particle-forming compositions containing fused pyrrolocarbazoles
US7795246B2 (en)	1998-08-06	2010-09-14	Cephalon, Inc.	Particle-forming compositions containing fused pyrrolocarbazoles
PT1372611E (pt) *	2001-03-26	2006-08-31	Novartis Ag	Composicao farmaceutica compreendendo uma estaurosporina francamente soluvel em agua, um tensioactivo et um polimero soluvel em agua
CA2444867C (en)	2001-05-16	2010-08-17	Novartis Ag	Combination comprising n-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2pyrimidine-amine and a chemotherapeutic agent
DE60213842T2 (de) *	2001-10-30	2007-09-06	Novartis Ag	Staurosporin-derivate als hemmer der flt3-rezeptor-tyrosinkinase-wirkung
GB0206215D0 (en)	2002-03-15	2002-05-01	Novartis Ag	Organic compounds
EP1531793A1 (de) *	2002-07-23	2005-05-25	Novartis AG	Augensalbenzusammensetzung mit einem arzneimittel, einer salbengrundlage und einem l slichmachenden/dispergierenden mittel
US7842791B2 (en)	2002-12-19	2010-11-30	Nancy Jean Britten	Dispersible pharmaceutical compositions
TWI324604B (en) *	2003-06-18	2010-05-11	Novartis Ag	New use of staurosporine derivatives
GB0512324D0 (en)	2005-06-16	2005-07-27	Novartis Ag	Organic compounds
GB0419159D0 (en) *	2004-08-27	2004-09-29	Novartis Ag	Organic compounds
GT200500310A (es) *	2004-11-19	2006-06-19		Compuestos organicos
JP5546860B2 (ja) *	2006-08-16	2014-07-09	ノバルティスアーゲー	高結晶性治療化合物の固体分散体を製造するための方法
FR2918566B1 (fr)	2007-07-11	2009-10-09	Pierre Fabre Medicament Sa	Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine.
US20090155352A1 (en) *	2007-11-20	2009-06-18	Cephalon, Inc.	Microemulsion containing indolocarbazole compound and dosage forms containing the same
EP2229936B1 (de) *	2009-03-09	2015-05-06	PharmaSol GmbH	Nanonisierte Testosteronformulierungen für verbesserte Bioverfügbarkeit
WO2011000811A2 (en) *	2009-06-30	2011-01-06	Novartis Ag	Organic compounds
US20120322776A1 (en) *	2009-12-22	2012-12-20	Leo Pharma A/S	Cutaneous composition comprising vitamin d analogue and a mixture of solvent and surfactants
JO3337B1 (ar)	2010-12-13	2019-03-13	Debiopharm Sa	تركيبات صيدلية تشمل أليسبوريفير
US9387446B2 (en) *	2011-09-22	2016-07-12	Ariel-University Research And Development Company Ltd.	Emulsions and methods of making emulsions
RU2742650C2 (ru) *	2015-12-09	2021-02-09	Фосфейдженикс Лимитед	Фармацевтический состав
MX383940B (es)	2015-12-09	2025-03-14	Phosphagenics Ltd	Formulación farmacéutica que contiene tocol fosfato.
IL267006B2 (en)	2016-12-21	2024-11-01	Phosphagenics Ltd	Process for phosphorylation of a complex alcohol with p4o10 at high temperatures, and products thereof
WO2021097256A1 (en)	2019-11-14	2021-05-20	Cohbar, Inc.	Cxcr4 antagonist peptides

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US4735939A (en)	1987-02-27	1988-04-05	The Dow Chemical Company	Insecticidal activity of staurosporine
US5093330A (en) *	1987-06-15	1992-03-03	Ciba-Geigy Corporation	Staurosporine derivatives substituted at methylamino nitrogen
DE3824034C1 (de) *	1988-07-15	1989-09-14	Gustav 7290 Freudenstadt De Memminger
KR0148748B1 (ko) *	1988-09-16	1998-08-17	장 크라메르, 한스 루돌프 하우스	사이클로스포린을 함유하는 약학조성물
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ATE265847T1 (de)	1997-07-29	2004-05-15	Upjohn Co	Selbstemulgierbare formulierung enthaltend lipophile verbindungen
PL192080B1 (pl)	1997-07-29	2006-08-31	Upjohn Co	Kompozycja farmaceutyczna zawierająca związek piranonowy
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AR013276A1 (es)	1998-07-31	2000-12-13	Panacea Biotec Ltd	Composicion de ciclosporina transparente
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1999
- 1999-02-16 GB GBGB9903547.9A patent/GB9903547D0/en not_active Ceased
2000
- 2000-02-14 CZ CZ20012931A patent/CZ303979B6/cs not_active IP Right Cessation
- 2000-02-14 KR KR1020017009391A patent/KR100880859B1/ko not_active Expired - Lifetime
- 2000-02-14 AT AT00909165T patent/ATE430554T1/de active
- 2000-02-14 JP JP2000599363A patent/JP5057610B2/ja not_active Expired - Fee Related
- 2000-02-14 DE DE60042151T patent/DE60042151D1/de not_active Expired - Lifetime
- 2000-02-14 ES ES00909165T patent/ES2326783T3/es not_active Expired - Lifetime
- 2000-02-14 HK HK02106758.7A patent/HK1045807B/zh not_active IP Right Cessation
- 2000-02-14 NZ NZ513529A patent/NZ513529A/en not_active IP Right Cessation
- 2000-02-14 SI SI200031035T patent/SI1152750T1/sl unknown
- 2000-02-14 WO PCT/EP2000/001196 patent/WO2000048571A1/en not_active Ceased
- 2000-02-14 CN CNB008038244A patent/CN100367930C/zh not_active Expired - Lifetime
- 2000-02-14 IL IL14451200A patent/IL144512A0/xx active IP Right Grant
- 2000-02-14 ID IDW00200101649A patent/ID30504A/id unknown
- 2000-02-14 CA CA2362277A patent/CA2362277C/en not_active Expired - Lifetime
- 2000-02-14 AR ARP000100627A patent/AR022589A1/es not_active Application Discontinuation
- 2000-02-14 EP EP00909165A patent/EP1152750B1/de not_active Expired - Lifetime
- 2000-02-14 RU RU2001124597/15A patent/RU2266121C2/ru active
- 2000-02-14 HU HU0105364A patent/HUP0105364A3/hu unknown
- 2000-02-14 PT PT00909165T patent/PT1152750E/pt unknown
- 2000-02-14 SK SK1172-2001A patent/SK286967B6/sk not_active IP Right Cessation
- 2000-02-14 KR KR1020087015449A patent/KR20080064914A/ko not_active Withdrawn
- 2000-02-14 AU AU31542/00A patent/AU765776B2/en not_active Expired
- 2000-02-14 PL PL350556A patent/PL198330B1/pl unknown
- 2000-02-14 BR BRPI0008228A patent/BRPI0008228B8/pt not_active IP Right Cessation
- 2000-02-14 PE PE2000000113A patent/PE20001499A1/es not_active Application Discontinuation
- 2000-02-14 TR TR2001/02385T patent/TR200102385T2/xx unknown
- 2000-02-14 DK DK00909165T patent/DK1152750T3/da active
- 2000-02-15 MY MYPI20000530A patent/MY128362A/en unknown
- 2000-03-13 TW TW089104503A patent/TWI240636B/zh not_active IP Right Cessation
2001
- 2001-02-14 ZA ZA200106677A patent/ZA200106677B/en unknown
- 2001-07-23 IL IL144512A patent/IL144512A/en not_active IP Right Cessation
- 2001-08-15 US US09/930,335 patent/US20020061873A1/en not_active Abandoned
- 2001-08-15 NO NO20013964A patent/NO331232B1/no not_active IP Right Cessation
2007
- 2007-09-21 US US11/859,077 patent/US8575147B2/en not_active Expired - Fee Related
2008
- 2008-07-04 EC EC2008003351A patent/ECSP083351A/es unknown
- 2008-07-07 IL IL192666A patent/IL192666A0/en unknown
2009
- 2009-07-31 CL CL2009001682A patent/CL2009001682A1/es unknown
2011
- 2011-08-05 AR ARP110102851A patent/AR082579A2/es not_active Application Discontinuation
2012
- 2012-01-05 JP JP2012000816A patent/JP2012111763A/ja active Pending
2013
- 2013-10-15 US US14/053,661 patent/US8722664B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
TWI240636B (en)	2005-10-01
ES2326783T3 (es)	2009-10-20
NO331232B1 (no)	2011-11-07
TR200102385T2 (tr)	2002-09-23
GB9903547D0 (en)	1999-04-07
PL198330B1 (pl)	2008-06-30
JP5057610B2 (ja)	2012-10-24
US20080070897A1 (en)	2008-03-20
ZA200106677B (en)	2003-01-14
IL144512A (en)	2011-03-31
ID30504A (id)	2001-12-13
WO2000048571A1 (en)	2000-08-24
SK11722001A3 (sk)	2001-12-03
DE60042151D1 (de)	2009-06-18
CZ20012931A3 (cs)	2001-11-14
KR100880859B1 (ko)	2009-01-30
ECSP083351A (es)	2008-08-29
HUP0105364A3 (en)	2003-02-28
US20020061873A1 (en)	2002-05-23
BRPI0008228B8 (pt)	2021-05-25
JP2012111763A (ja)	2012-06-14
BR0008228A (pt)	2001-10-30
US8722664B2 (en)	2014-05-13
MY128362A (en)	2007-01-31
IL144512A0 (en)	2002-05-23
NO20013964L (no)	2001-10-15
KR20080064914A (ko)	2008-07-09
AU3154200A (en)	2000-09-04
AU765776B2 (en)	2003-10-02
US8575147B2 (en)	2013-11-05
CN100367930C (zh)	2008-02-13
CL2009001682A1 (es)	2010-07-23
CZ303979B6 (cs)	2013-07-31
AR022589A1 (es)	2002-09-04
PL350556A1 (en)	2002-12-16
NO20013964D0 (no)	2001-08-15
SK286967B6 (sk)	2009-08-06
DK1152750T3 (da)	2009-08-24
EP1152750A1 (de)	2001-11-14
CA2362277C (en)	2010-03-30
CA2362277A1 (en)	2000-08-24
HK1045807B (zh)	2008-12-05
PT1152750E (pt)	2009-08-07
SI1152750T1 (sl)	2009-10-31
EP1152750B1 (de)	2009-05-06
RU2266121C2 (ru)	2005-12-20
HK1045807A1 (zh)	2002-12-13
CN1339963A (zh)	2002-03-13
JP2002537242A (ja)	2002-11-05
PE20001499A1 (es)	2001-01-12
IL192666A0 (en)	2009-02-11
KR20010093281A (ko)	2001-10-27
NZ513529A (en)	2003-10-31
BRPI0008228B1 (pt)	2016-08-23
HUP0105364A2 (hu)	2002-05-29
AR082579A2 (es)	2012-12-19
US20140056974A1 (en)	2014-02-27

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2009-12-15

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