ATE430811T1 - Mit uv-licht anregbare fluoreszenzenergietransfer-farbstoffe - Google Patents
Mit uv-licht anregbare fluoreszenzenergietransfer-farbstoffeInfo
- Publication number
- ATE430811T1 ATE430811T1 AT00950997T AT00950997T ATE430811T1 AT E430811 T1 ATE430811 T1 AT E430811T1 AT 00950997 T AT00950997 T AT 00950997T AT 00950997 T AT00950997 T AT 00950997T AT E430811 T1 ATE430811 T1 AT E430811T1
- Authority
- AT
- Austria
- Prior art keywords
- energy transfer
- dye
- transfer dyes
- light
- fluorescence energy
- Prior art date
Links
- 239000000975 dye Substances 0.000 title abstract 13
- 238000010521 absorption reaction Methods 0.000 abstract 2
- ZYGHJZDHTFUPRJ-UHFFFAOYSA-N coumarin Chemical group C1=CC=C2OC(=O)C=CC2=C1 ZYGHJZDHTFUPRJ-UHFFFAOYSA-N 0.000 abstract 2
- 229960000956 coumarin Drugs 0.000 abstract 1
- 235000001671 coumarin Nutrition 0.000 abstract 1
- 125000005581 pyrene group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B11/00—Diaryl- or thriarylmethane dyes
- C09B11/04—Diaryl- or thriarylmethane dyes derived from triarylmethanes, i.e. central C-atom is substituted by amino, cyano, alkyl
- C09B11/10—Amino derivatives of triarylmethanes
- C09B11/24—Phthaleins containing amino groups ; Phthalanes; Fluoranes; Phthalides; Rhodamine dyes; Phthaleins having heterocyclic aryl rings; Lactone or lactame forms of triarylmethane dyes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Decoration By Transfer Pictures (AREA)
- Cosmetics (AREA)
- Luminescent Compositions (AREA)
- Lasers (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/385,352 US6358684B1 (en) | 1999-08-27 | 1999-08-27 | UV excitable fluorescent energy transfer dyes |
| PCT/US2000/021519 WO2001016369A2 (en) | 1999-08-27 | 2000-08-04 | Uv excitable fluorescent energy transfer dyes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE430811T1 true ATE430811T1 (de) | 2009-05-15 |
Family
ID=23521062
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00950997T ATE430811T1 (de) | 1999-08-27 | 2000-08-04 | Mit uv-licht anregbare fluoreszenzenergietransfer-farbstoffe |
Country Status (8)
| Country | Link |
|---|---|
| US (11) | US6358684B1 (de) |
| EP (1) | EP1212457B1 (de) |
| JP (1) | JP2003508065A (de) |
| AT (1) | ATE430811T1 (de) |
| AU (2) | AU6401000A (de) |
| CA (1) | CA2382663A1 (de) |
| DE (1) | DE60042163D1 (de) |
| WO (1) | WO2001016369A2 (de) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6147205A (en) * | 1995-12-15 | 2000-11-14 | Affymetrix, Inc. | Photocleavable protecting groups and methods for their use |
| US20110028350A1 (en) * | 1995-12-15 | 2011-02-03 | Affymetrix, Inc. | Photocleavable protecting groups |
| US7388092B2 (en) * | 1996-05-03 | 2008-06-17 | Applera Corporation | Oligonucleotides and analogs labeled with energy transfer dyes |
| US5945526A (en) * | 1996-05-03 | 1999-08-31 | Perkin-Elmer Corporation | Energy transfer dyes with enhanced fluorescence |
| US7825237B2 (en) * | 1996-05-03 | 2010-11-02 | Applied Biosystems, Llc | Oligonucleotides and analogs labeled with energy transfer dyes |
| US7079241B2 (en) * | 2000-04-06 | 2006-07-18 | Invitrogen Corp. | Spatial positioning of spectrally labeled beads |
| US6358684B1 (en) * | 1999-08-27 | 2002-03-19 | Pe Corporation | UV excitable fluorescent energy transfer dyes |
| JP2005523232A (ja) * | 2000-09-11 | 2005-08-04 | アフィメトリックス インコーポレイテッド | 光切断可能保護基 |
| US7579463B2 (en) * | 2000-12-20 | 2009-08-25 | Life Technologies Corporation | Crown ether derivatives |
| US7129346B2 (en) * | 2000-12-20 | 2006-10-31 | Molecular Probes, Inc. | Crown ether derivatives |
| US6962992B2 (en) | 2000-12-20 | 2005-11-08 | Molecullar Probes, Inc. | Crown ether derivatives |
| TW589348B (en) * | 2001-08-01 | 2004-06-01 | Ind Tech Res Inst | Dyes for recording layer of the high density optical recording disc |
| CN1665790A (zh) * | 2002-05-03 | 2005-09-07 | 莫莱丘莱尔探针公司 | 用于检测和分离磷酸化分子的组合物及方法 |
| US20040171034A1 (en) * | 2002-05-03 | 2004-09-02 | Brian Agnew | Compositions and methods for detection and isolation of phosphorylated molecules |
| US7445894B2 (en) * | 2002-05-03 | 2008-11-04 | Molecular Probes, Inc. | Compositions and methods for detection and isolation of phosphorylated molecules |
| AU2003272704A1 (en) * | 2002-09-25 | 2004-04-19 | Amersham Biosciences Corp | Energy transfer dyes, terminators and use thereof |
| WO2004070697A1 (ja) * | 2003-02-03 | 2004-08-19 | Sharp Kabushiki Kaisha | 液晶表示装置 |
| US9156986B2 (en) * | 2003-04-03 | 2015-10-13 | Enzo Life Sciences, Inc. | Multisignal labeling reagents and processes and uses therefor |
| US8445702B2 (en) * | 2003-05-05 | 2013-05-21 | Life Technologies Corporation | Zinc binding compounds and their method of use |
| US20050250214A1 (en) * | 2004-05-05 | 2005-11-10 | Gee Kyle R | Zinc binding compounds and their method of use |
| CA2445420A1 (en) * | 2003-07-29 | 2005-01-29 | Invitrogen Corporation | Kinase and phosphatase assays |
| US7619059B2 (en) * | 2003-07-29 | 2009-11-17 | Life Technologies Corporation | Bimolecular optical probes |
| US7727752B2 (en) | 2003-07-29 | 2010-06-01 | Life Technologies Corporation | Kinase and phosphatase assays |
| US7271265B2 (en) * | 2003-08-11 | 2007-09-18 | Invitrogen Corporation | Cyanine compounds and their application as quenching compounds |
| US20050064485A1 (en) * | 2003-09-12 | 2005-03-24 | Kurt Vogel | Multiplex binding and activity assays |
| US20050214807A1 (en) * | 2003-11-19 | 2005-09-29 | Iain Johnson | Environmental sensitive fluorogenic compounds and their application for singlet oxygen and protein detection |
| US7776529B2 (en) | 2003-12-05 | 2010-08-17 | Life Technologies Corporation | Methine-substituted cyanine dye compounds |
| EP2607431B1 (de) * | 2003-12-05 | 2016-08-24 | Life Technologies Corporation | Cyanin Farbstoffverbindungen |
| WO2005071096A2 (en) | 2004-01-21 | 2005-08-04 | Molecular Probes, Inc. | Derivatives of cephalosporin and clavulanic acid for detecting beta-lacamase in a sample |
| WO2006023231A2 (en) | 2004-07-27 | 2006-03-02 | Molecular Probes, Inc. | Fluorescent metal ion indicators with large stokes shift |
| US8338093B2 (en) * | 2004-12-31 | 2012-12-25 | Affymetrix, Inc. | Primer array synthesis and validation |
| US7547775B2 (en) * | 2004-12-31 | 2009-06-16 | Affymetrix, Inc. | Parallel preparation of high fidelity probes in an array format |
| JP5306811B2 (ja) * | 2005-05-11 | 2013-10-02 | ライフ テクノロジーズ コーポレーション | 2本鎖dnaへの高い選択性を有する蛍光化学物質及びそれらの使用 |
| US20070134685A1 (en) * | 2005-09-06 | 2007-06-14 | Invitrogen Corporation | Control of chemical modification |
| US7521577B2 (en) | 2006-01-12 | 2009-04-21 | Molecular Probes, Inc. | Heavy metal binding compounds and their method of use |
| US8586743B2 (en) * | 2007-01-30 | 2013-11-19 | Life Technologies Corporation | Labeling reagents and methods of their use |
| US8513451B2 (en) * | 2007-05-30 | 2013-08-20 | Hee Chol Kang | Fluorescent phospholipase A2 indicators |
| EP2193024A4 (de) | 2007-09-25 | 2013-11-06 | Entrotech Inc | Farbersatzfilme, verbundstoffe daraus und verwandte verfahren |
| US10981371B2 (en) | 2008-01-19 | 2021-04-20 | Entrotech, Inc. | Protected graphics and related methods |
| US8367193B1 (en) * | 2008-03-20 | 2013-02-05 | Inmat Inc | Aqueous nanocomposite dispersions containing invisible marker dye for transparent barrier coatings and preparations and use thereof |
| CN102084003A (zh) | 2008-04-04 | 2011-06-01 | 生命科技公司 | 用于成像和测序的扫描系统和方法 |
| US9790318B2 (en) * | 2008-09-26 | 2017-10-17 | entrotech, inc | Methods for polymerizing films in-situ |
| DE102008064164A1 (de) * | 2008-12-22 | 2010-07-01 | Leica Microsystems Cms Gmbh | Verfahren zur räumlich hochauflösenden stochastischen Untersuchung einer mit einer Substanz markierten Struktur einer Probe |
| US9249306B2 (en) | 2009-02-18 | 2016-02-02 | Carnegie Mellon University | Quenched dendrimeric dyes for florescence detection |
| US8828303B2 (en) | 2010-03-31 | 2014-09-09 | Entrotech, Inc. | Methods for polymerizing films in-situ using a radiation source |
| WO2011150079A1 (en) | 2010-05-25 | 2011-12-01 | Carnegie Mellon University | Targeted probes of cellular physiology |
| US8901578B2 (en) | 2011-05-10 | 2014-12-02 | Rohm Co., Ltd. | LED module having LED chips as light source |
| CN103131206A (zh) * | 2011-12-02 | 2013-06-05 | 中国科学院理化技术研究所 | 吡唑并吡啶类苯并香豆素染料衍生物及其合成方法和用途 |
| CN107429075B (zh) | 2014-11-17 | 2022-11-01 | 卡内基梅隆大学 | 可激活的双组份光敏剂 |
| SI3419826T1 (sl) | 2016-09-20 | 2026-01-30 | Ppg Advanced Surface Technologies, Llc | Metoda oblikovanja aplikacij barvne folije, aplikacije barvne folije, izdelki in uporaba |
| WO2018092034A1 (en) * | 2016-11-16 | 2018-05-24 | Panda Koustubh | Novel in-vivo probe for real time longitudinal monitoring of inducible nitric-oxide synthase in living cells and animals |
| EP3775052B1 (de) | 2018-03-30 | 2024-06-05 | Becton, Dickinson and Company | Wasserlösliche polymere farbstoffe mit seitenständigen chromophoren |
| CN113195639A (zh) | 2018-12-20 | 2021-07-30 | 生命技术公司 | 非对称罗丹明染料和其在生物测定中的用途 |
| SG11202106124UA (en) | 2018-12-20 | 2021-07-29 | Life Technologies Corp | Modified rhodamine dye and use thereof in biological assays |
| CN111303111B (zh) * | 2020-03-23 | 2023-01-10 | 华东理工大学 | 一类黄菁近红外二区染料、制备方法及荧光成像应用 |
| US12359068B2 (en) * | 2023-02-10 | 2025-07-15 | Singular Genomics Systems, Inc. | Rhodamine fluorescent compounds and production methods thereof |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2157572A (en) * | 1933-02-25 | 1939-05-09 | Rca Corp | Velocity measuring device |
| US5118802A (en) | 1983-12-20 | 1992-06-02 | California Institute Of Technology | DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside |
| EP0201751A2 (de) | 1985-05-08 | 1986-11-20 | Abbott Laboratories | 4-Aminomethylfluoreszeinderivate zur Verwendung in Fluoreszenz-Polarisationsimmunotesten |
| CA1273552A (en) | 1985-12-23 | 1990-09-04 | Michael J. Heller | Fluorescent stokes shift probes for polynucleotide hybridization assays |
| US4996143A (en) | 1985-12-23 | 1991-02-26 | Syngene, Inc. | Fluorescent stokes shift probes for polynucleotide hybridization |
| US6048982A (en) | 1986-04-18 | 2000-04-11 | Carnegie Mellon University | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods |
| US4777128A (en) | 1986-05-27 | 1988-10-11 | Ethigen Corporation | Fluorescence immunoassay involving energy transfer between two fluorophores |
| US5254477A (en) | 1986-06-25 | 1993-10-19 | Trustees Of Tufts College | Flourescence intramolecular energy transfer conjugate compositions and detection methods |
| EP0366685B1 (de) | 1987-06-24 | 1994-10-19 | Howard Florey Institute Of Experimental Physiology And Medicine | Nukleosid-derivate |
| BE1000858A6 (nl) | 1987-07-13 | 1989-04-18 | Italo Suisse | Vorm voor het vervaardigen van chocoladevoorwerpen uit minstens twee verschillende kleuren en de hierbij toegepaste werkwijze. |
| EP0310361A3 (de) | 1987-09-30 | 1989-05-24 | Beckman Instruments, Inc. | Aus drei Verzahnungen bestehendes Konjugat und Verfahren zu seiner Verwendung |
| US5188934A (en) | 1989-11-14 | 1993-02-23 | Applied Biosystems, Inc. | 4,7-dichlorofluorescein dyes as molecular probes |
| US5342789A (en) | 1989-12-14 | 1994-08-30 | Sensor Technologies, Inc. | Method and device for detecting and quantifying glucose in body fluids |
| US5401847A (en) | 1990-03-14 | 1995-03-28 | Regents Of The University Of California | DNA complexes with dyes designed for energy transfer as fluorescent markers |
| US5326692B1 (en) | 1992-05-13 | 1996-04-30 | Molecular Probes Inc | Fluorescent microparticles with controllable enhanced stokes shift |
| DK0537270T3 (da) | 1990-07-02 | 1999-06-07 | Univ California | Påvisning af analytter ved overføring af fluorescensenergi |
| US5340716A (en) | 1991-06-20 | 1994-08-23 | Snytex (U.S.A.) Inc. | Assay method utilizing photoactivated chemiluminescent label |
| JP3097205B2 (ja) | 1991-09-05 | 2000-10-10 | 株式会社日立製作所 | 電気泳動分離検出方法 |
| CA2119126C (en) | 1991-09-16 | 1996-09-03 | Molecular Probes, Inc. | Dimers of unsymmetrical cyanine dyes |
| EP1067134B1 (de) | 1991-11-07 | 2004-07-28 | Nanotronics, Inc. | Hybridisierung von mit Chromophoren und Fluorophoren konjugierten Polynukleotiden zur Erzeugung eines Donor-Donor Energietransfersystems |
| US5747244A (en) | 1991-12-23 | 1998-05-05 | Chiron Corporation | Nucleic acid probes immobilized on polystyrene surfaces |
| EP0601889A2 (de) | 1992-12-10 | 1994-06-15 | Maine Medical Center Research Institute | Nukleinsäure-Sonden |
| US5410030A (en) | 1993-04-05 | 1995-04-25 | Molecular Probes, Inc. | Dimers of unsymmetrical cyanine dyes containing pyridinium moieties |
| GB9310978D0 (en) | 1993-05-27 | 1993-07-14 | Zeneca Ltd | Compounds |
| US5824799A (en) | 1993-09-24 | 1998-10-20 | Biosite Diagnostics Incorporated | Hybrid phthalocyanine derivatives and their uses |
| US6238931B1 (en) | 1993-09-24 | 2001-05-29 | Biosite Diagnostics, Inc. | Fluorescence energy transfer in particles |
| US5654419A (en) * | 1994-02-01 | 1997-08-05 | The Regents Of The University Of California | Fluorescent labels and their use in separations |
| US6028190A (en) | 1994-02-01 | 2000-02-22 | The Regents Of The University Of California | Probes labeled with energy transfer coupled dyes |
| US5869255A (en) | 1994-02-01 | 1999-02-09 | The Regents Of The University Of California | Probes labeled with energy transfer couples dyes exemplified with DNA fragment analysis |
| EP0678742B1 (de) * | 1994-04-21 | 2002-07-24 | Hitachi, Ltd. | Überwachungsverfahren einer Färbelösung für Partikelanalysen und Kalibrierungsverfahren von Partikelanalysen |
| US5565554A (en) | 1994-07-29 | 1996-10-15 | The Regents Of The University Of California | Dimeric fluorescent energy transfer dyes comprising asymmetric cyanine azole-indolenine chromophores |
| US5843658A (en) | 1995-03-10 | 1998-12-01 | Hamamatsu Photonics K.K. | Method of measuring oligonucleotide decomposing activity |
| US5741657A (en) | 1995-03-20 | 1998-04-21 | The Regents Of The University Of California | Fluorogenic substrates for β-lactamase and methods of use |
| US5661035A (en) | 1995-06-07 | 1997-08-26 | The Regents Of The University Of California | Voltage sensing by fluorescence resonance energy transfer |
| US6008373A (en) | 1995-06-07 | 1999-12-28 | Carnegie Mellon University | Fluorescent labeling complexes with large stokes shift formed by coupling together cyanine and other fluorochromes capable of resonance energy transfer |
| US5728528A (en) * | 1995-09-20 | 1998-03-17 | The Regents Of The University Of California | Universal spacer/energy transfer dyes |
| CA2240667A1 (en) | 1995-12-18 | 1997-06-26 | Washington University | Method for nucleic acid analysis using fluorescence resonance energy transfer |
| US6803188B1 (en) | 1996-01-31 | 2004-10-12 | The Regents Of The University Of California | Tandem fluorescent protein constructs |
| US5800996A (en) * | 1996-05-03 | 1998-09-01 | The Perkin Elmer Corporation | Energy transfer dyes with enchanced fluorescence |
| US7388092B2 (en) * | 1996-05-03 | 2008-06-17 | Applera Corporation | Oligonucleotides and analogs labeled with energy transfer dyes |
| US5863727A (en) * | 1996-05-03 | 1999-01-26 | The Perkin-Elmer Corporation | Energy transfer dyes with enhanced fluorescence |
| US5945526A (en) * | 1996-05-03 | 1999-08-31 | Perkin-Elmer Corporation | Energy transfer dyes with enhanced fluorescence |
| US5853992A (en) * | 1996-10-04 | 1998-12-29 | The Regents Of The University Of California | Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels |
| EP0967219A4 (de) * | 1997-07-11 | 2002-09-11 | Rikagaku Kenkyusho | Verbindungen mit energieübertragungsfunktion und eine methode zur dna-basensequenzierung unter verwendung dieser verbindungen |
| ATE299190T1 (de) * | 1998-02-04 | 2005-07-15 | Amersham Biosciences Corp | Didesoxy farbterminatoren |
| US6218124B1 (en) * | 1999-08-27 | 2001-04-17 | Pe Corporation | Method for detecting oligonucleotides using UV light source |
| US6358684B1 (en) | 1999-08-27 | 2002-03-19 | Pe Corporation | UV excitable fluorescent energy transfer dyes |
-
1999
- 1999-08-27 US US09/385,352 patent/US6358684B1/en not_active Expired - Lifetime
-
2000
- 2000-08-04 EP EP00950997A patent/EP1212457B1/de not_active Expired - Lifetime
- 2000-08-04 WO PCT/US2000/021519 patent/WO2001016369A2/en not_active Ceased
- 2000-08-04 CA CA002382663A patent/CA2382663A1/en not_active Abandoned
- 2000-08-04 DE DE60042163T patent/DE60042163D1/de not_active Expired - Lifetime
- 2000-08-04 AT AT00950997T patent/ATE430811T1/de not_active IP Right Cessation
- 2000-08-04 JP JP2001520914A patent/JP2003508065A/ja active Pending
- 2000-08-04 AU AU64010/00A patent/AU6401000A/en not_active Abandoned
-
2001
- 2001-07-10 US US09/902,562 patent/US20010049109A1/en not_active Abandoned
- 2001-07-10 US US09/902,561 patent/US20020058272A1/en not_active Abandoned
-
2003
- 2003-02-07 US US10/359,931 patent/US7012141B2/en not_active Expired - Lifetime
- 2003-02-07 US US10/359,826 patent/US7157572B2/en not_active Expired - Fee Related
-
2006
- 2006-02-28 AU AU2006200848A patent/AU2006200848A1/en not_active Abandoned
- 2006-03-10 US US11/372,544 patent/US7402671B2/en not_active Expired - Fee Related
- 2006-07-31 US US11/497,159 patent/US7378517B2/en not_active Expired - Fee Related
-
2008
- 2008-05-23 US US12/126,813 patent/US7888507B2/en not_active Expired - Fee Related
- 2008-07-18 US US12/176,302 patent/US20090062543A1/en not_active Abandoned
-
2010
- 2010-12-02 US US12/959,205 patent/US8129529B2/en not_active Expired - Fee Related
-
2012
- 2012-01-30 US US13/361,863 patent/US8604186B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20090062543A1 (en) | 2009-03-05 |
| WO2001016369A3 (en) | 2001-10-04 |
| US20090031506A1 (en) | 2009-02-05 |
| AU2006200848A1 (en) | 2006-03-23 |
| US7157572B2 (en) | 2007-01-02 |
| DE60042163D1 (de) | 2009-06-18 |
| US6358684B1 (en) | 2002-03-19 |
| EP1212457A2 (de) | 2002-06-12 |
| US7402671B2 (en) | 2008-07-22 |
| EP1212457B1 (de) | 2009-05-06 |
| JP2003508065A (ja) | 2003-03-04 |
| US20040076971A1 (en) | 2004-04-22 |
| WO2001016369A2 (en) | 2001-03-08 |
| US7012141B2 (en) | 2006-03-14 |
| US20060155123A1 (en) | 2006-07-13 |
| US8129529B2 (en) | 2012-03-06 |
| US8604186B2 (en) | 2013-12-10 |
| US20120196295A1 (en) | 2012-08-02 |
| US20060029936A9 (en) | 2006-02-09 |
| AU6401000A (en) | 2001-03-26 |
| US20030165961A1 (en) | 2003-09-04 |
| US20010049109A1 (en) | 2001-12-06 |
| US7888507B2 (en) | 2011-02-15 |
| US20060269958A1 (en) | 2006-11-30 |
| US20020058272A1 (en) | 2002-05-16 |
| US7378517B2 (en) | 2008-05-27 |
| US20110077415A1 (en) | 2011-03-31 |
| CA2382663A1 (en) | 2001-03-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE430811T1 (de) | Mit uv-licht anregbare fluoreszenzenergietransfer-farbstoffe | |
| CO4230033A1 (es) | Uso de compuestos absorbentes y/o fluorescentes en la region infrarroja como marcadores para liquidos | |
| ES2171019T3 (es) | Lampara halogena de tension alta/media y su casquillo. | |
| CA2113106A1 (en) | Fluorescent Microparticles with Controllable Enhanced Stokes Shift | |
| ATE431970T1 (de) | Licht emittierendes material und organische leuchtdiode | |
| WO2003009012A3 (en) | Edge-lit panel with fluorescent transparent plate | |
| WO1999002026A3 (en) | Fluorescent dye added to epoxy of light emitting diode lens | |
| DE59808440D1 (de) | Organische lichtemittierende Diode mit Terbiumkomplex | |
| AR033472A1 (es) | Concentrados de agentes anticongelantes que contienen el colorante c.i. reactive violet 5 | |
| DE3684037D1 (de) | Chemilumineszente zusammensetzung. | |
| DE69700935D1 (de) | Energieübertragungsfarbstoffe mit verbesserter Fluoreszenz | |
| ES2134158B1 (es) | Absorbedores de uv benzotriazolicos de alta durabilidad. | |
| JPS5512429A (en) | Radioactive image reader | |
| ATE320000T1 (de) | Ein biolumineszenz resonanz energie transfer (bret) system mit breitem spektralen resolution zwischen donator- und akzeptor-emission wellenlänge und ihre anwendung | |
| ES2029767A6 (es) | Procedimiento de tenido o estampado tricromatico de sustratos organicos nitrogenados. | |
| TW200615582A (en) | Color conversion filter substrate and a multicolor light emitting device employing the substrate | |
| US4989215A (en) | Laser pumping cavity | |
| AR033274A1 (es) | Formulaciones de peroxido y poliester coloreadas | |
| DE69009561D1 (de) | Halbleiterlaser zur selektiven Ausstrahlung von Licht mit verschiedenen Wellenlängen. | |
| ATE427555T1 (de) | Braunungsgerat | |
| CN202812926U (zh) | 一种漫反射高光效led灯管 | |
| DE50212890D1 (de) | Lichthärtegerät | |
| ES2161152B1 (es) | Nuevos polimeros portadores en su estructura de colorantes dipirrometinicos y su utilizacion como laseres. | |
| RU93034822A (ru) | Волоконный световод оптического квантового усилителя | |
| SE0003733D0 (sv) | Ljusabsorbator |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |