ATE430812T1 - Materialien und verfahren zum einfangen von krankheitserregern und zur abtrennung von aurintricarbonsäure aus einer probe - Google Patents
Materialien und verfahren zum einfangen von krankheitserregern und zur abtrennung von aurintricarbonsäure aus einer probeInfo
- Publication number
- ATE430812T1 ATE430812T1 AT04801986T AT04801986T ATE430812T1 AT E430812 T1 ATE430812 T1 AT E430812T1 AT 04801986 T AT04801986 T AT 04801986T AT 04801986 T AT04801986 T AT 04801986T AT E430812 T1 ATE430812 T1 AT E430812T1
- Authority
- AT
- Austria
- Prior art keywords
- sample
- separate
- materials
- methods
- aurintricarboxylic acid
- Prior art date
Links
- GIXWDMTZECRIJT-UHFFFAOYSA-N aurintricarboxylic acid Chemical compound C1=CC(=O)C(C(=O)O)=CC1=C(C=1C=C(C(O)=CC=1)C(O)=O)C1=CC=C(O)C(C(O)=O)=C1 GIXWDMTZECRIJT-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000000463 material Substances 0.000 title 1
- 244000052769 pathogen Species 0.000 title 1
- 102000016911 Deoxyribonucleases Human genes 0.000 abstract 1
- 108010053770 Deoxyribonucleases Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000000633 nuclear envelope Anatomy 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/02—Peptides being immobilised on, or in, an organic carrier
- C07K17/10—Peptides being immobilised on, or in, an organic carrier the carrier being a carbohydrate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
- C07C65/40—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
- C12N15/101—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by chromatography, e.g. electrophoresis, ion-exchange, reverse phase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/24—Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/34—Purifying; Cleaning
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pathology (AREA)
- Urology & Nephrology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Neurosurgery (AREA)
- Food Science & Technology (AREA)
- Toxicology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Sustainable Development (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/604,779 US7998699B2 (en) | 2002-08-15 | 2003-08-15 | Early detection of pathogens in blood |
| US48189204P | 2004-01-14 | 2004-01-14 | |
| PCT/US2004/026606 WO2005021799A2 (en) | 2003-08-15 | 2004-08-16 | Materials and methods for capture of pathogens and removal of aurintricarboxylic acid from a sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE430812T1 true ATE430812T1 (de) | 2009-05-15 |
Family
ID=34840999
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT09159214T ATE510931T1 (de) | 2003-08-15 | 2004-08-16 | Materialien und verfahren zur erfassung von pathogenen und entfernung von aurin- tricarbonsäure aus einer probe |
| AT04801986T ATE430812T1 (de) | 2003-08-15 | 2004-08-16 | Materialien und verfahren zum einfangen von krankheitserregern und zur abtrennung von aurintricarbonsäure aus einer probe |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT09159214T ATE510931T1 (de) | 2003-08-15 | 2004-08-16 | Materialien und verfahren zur erfassung von pathogenen und entfernung von aurin- tricarbonsäure aus einer probe |
Country Status (13)
| Country | Link |
|---|---|
| US (12) | US7416843B2 (de) |
| EP (3) | EP2112232B1 (de) |
| JP (2) | JP4662932B2 (de) |
| AT (2) | ATE510931T1 (de) |
| AU (2) | AU2004269340B2 (de) |
| DE (1) | DE602004020999D1 (de) |
| DK (2) | DK1654387T3 (de) |
| ES (1) | ES2325445T3 (de) |
| NO (1) | NO20061189L (de) |
| PL (2) | PL2103694T3 (de) |
| PT (2) | PT2103694E (de) |
| SI (1) | SI1654387T1 (de) |
| WO (1) | WO2005021799A2 (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7998699B2 (en) | 2002-08-15 | 2011-08-16 | University Of South Florida | Early detection of pathogens in blood |
| DK1654387T3 (da) | 2003-08-15 | 2009-06-22 | Univ South Florida | Materialer og fremgangsmåder til indfangning af patogener og fjernelse af aurintricarboxylsyre fra en pröve |
| CY1110678T1 (el) * | 2003-08-15 | 2015-06-10 | University Of South Florida | Υλικα και μεθοδοι για την παγιδευση παθογονων και την απομακρυνση του χρυσινοτρικαρβοξυλικου οξεος απο ενα δειγμα |
| MX2008007716A (es) | 2005-12-13 | 2008-09-26 | Exthera Ab | Metodo para eliminar extra corporalmente de la sangre un microbio patogeno, una celula inflamatoria o una proteina inflamatoria. |
| CA2576682A1 (en) | 2006-03-08 | 2007-09-08 | Martinrea International Inc. | Electrolyte delivery system |
| WO2008118566A2 (en) * | 2007-02-28 | 2008-10-02 | Ge Healthcare Bio-Sciences Corp. | Ambient temperature stable chemical/biological reagents on membranes or filters |
| CN106178161B (zh) | 2009-12-01 | 2020-12-22 | 艾克塞拉医疗公司 | 使用固定于表面的多糖从血液中去除细胞因子的方法 |
| EP2333105A1 (de) | 2009-12-08 | 2011-06-15 | Koninklijke Philips Electronics N.V. | Selektive Lyse von Zellen |
| US20110225809A1 (en) * | 2010-03-17 | 2011-09-22 | Alan Francis Daher | Apparatus for removably attaching an item to a surface |
| AU2011303467C1 (en) * | 2010-09-15 | 2017-03-09 | Debiopharm International Sa | Method for separating target molecules or particles from fibrinogen-containing samples including blood components |
| WO2012112724A1 (en) | 2011-02-15 | 2012-08-23 | Exthera Medical, Llc | Device and method for removal of blood-borne pathogens, toxins and inflammatory cytokines |
| JP2013055888A (ja) * | 2011-09-07 | 2013-03-28 | Toyobo Co Ltd | 血液培養サンプルからの迅速かつ簡便な細菌検出 |
| WO2013188073A1 (en) | 2012-06-13 | 2013-12-19 | Exthera Medical, Llc | Use of heparin and carbohydrates to treat cancer |
| FR3001464B1 (fr) | 2013-01-25 | 2016-02-26 | Biomerieux Sa | Procede d'isolement specifique d'acides nucleiques d'interet |
| FR3002452B1 (fr) * | 2013-02-28 | 2016-02-12 | Dermaconcept Jmc | Composition dermatologique antimicrobienne topique |
| BR112015032134B1 (pt) | 2013-06-24 | 2022-05-10 | Exthera Medical Corporation | Método de ligação em ponto de extremidade de uma manose não redutora a um substrato e esfera possuindo uma manose ligada em ponto de extremidade |
| EP3065796B1 (de) * | 2013-11-08 | 2020-04-15 | ExThera Medical Corporation | Verfahren zur diagnose von infektionskrankheiten unter verwendung von adsorptionsmedien |
| DE15782250T1 (de) | 2014-04-24 | 2017-08-10 | Exthera Medical Corporation | Verfahren zur Entfernung von Bakterien aus Blut unter Verwendung einer hohen Durchflussrate |
| KR20170060062A (ko) | 2014-09-22 | 2017-05-31 | 엑스테라 메디컬 코퍼레이션 | 웨어러블 혈액관류 장치 |
| CN104749009B (zh) * | 2015-03-30 | 2018-05-04 | 上海云泽生物科技有限公司 | 用于免疫分析的免疫抑制剂药物提取试剂 |
| WO2017151797A1 (en) | 2016-03-02 | 2017-09-08 | Exthera Medical Corporation | Method for treating drug intoxication |
| US11911551B2 (en) | 2016-03-02 | 2024-02-27 | Exthera Medical Corporation | Method for treating drug intoxication |
| GB2557654A (en) * | 2016-12-14 | 2018-06-27 | Uea Enterprises Ltd | Method for nucleic acid depletion |
| WO2018222709A2 (en) | 2017-06-01 | 2018-12-06 | Nantomics, Llc | Dna stabilization of rna |
| BR112021021141A2 (pt) | 2019-05-16 | 2021-12-14 | Exthera Medical Corp | Método para modular estrutura glicocalyx endotelial |
| US20220354932A1 (en) * | 2019-09-06 | 2022-11-10 | The Trustees Of Indiana University | Novel compositions for disrupting biofilms |
| AU2022291168A1 (en) * | 2021-06-08 | 2024-01-04 | Dna Genotek Inc. | Low ph composition and method for stabilizing nucleic acids in biological samples |
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| US3378443A (en) | 1966-04-05 | 1968-04-16 | American Cyanamid Co | Anhydrous liquid suspensions of biologics |
| US4693972A (en) | 1984-01-16 | 1987-09-15 | Becton, Dickinson And Company | Composition and method for rapid detection of microorganisms in clinical samples |
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| US6027877A (en) | 1993-11-04 | 2000-02-22 | Gene Check, Inc. | Use of immobilized mismatch binding protein for detection of mutations and polymorphisms, purification of amplified DNA samples and allele identification |
| EP0763754B1 (de) | 1995-09-13 | 2003-01-08 | Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) | Kontaktlinse auf Basis photogehärteter Hyaluronsäure |
| US6825047B1 (en) | 1996-04-03 | 2004-11-30 | Applera Corporation | Device and method for multiple analyte detection |
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| US6091979A (en) | 1998-07-07 | 2000-07-18 | Children's Medical Center Corporation | Subdural electrode arrays for monitoring cortical electrical activity |
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| US7192445B2 (en) | 2000-12-06 | 2007-03-20 | Astra Tech Ab | Medical prosthetic devices and implants having improved biocompatibility |
| DE10108483A1 (de) | 2001-02-22 | 2002-09-05 | Bayer Ag | Phosphorhaltige Polymere für optischen Signalwandler |
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| CN100494360C (zh) | 2001-03-22 | 2009-06-03 | 博奥生物有限公司 | 细胞分离方法及其应用 |
| EP2360234B1 (de) | 2001-11-30 | 2015-07-22 | Fluidigm Corporation | Mikrofluide Vorrichtung und Verfahren seiner Verwendung |
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| US7998699B2 (en) | 2002-08-15 | 2011-08-16 | University Of South Florida | Early detection of pathogens in blood |
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| DK1654387T3 (da) | 2003-08-15 | 2009-06-22 | Univ South Florida | Materialer og fremgangsmåder til indfangning af patogener og fjernelse af aurintricarboxylsyre fra en pröve |
-
2004
- 2004-08-16 DK DK04801986T patent/DK1654387T3/da active
- 2004-08-16 SI SI200431179T patent/SI1654387T1/sl unknown
- 2004-08-16 WO PCT/US2004/026606 patent/WO2005021799A2/en not_active Ceased
- 2004-08-16 PT PT09159214T patent/PT2103694E/pt unknown
- 2004-08-16 DE DE602004020999T patent/DE602004020999D1/de not_active Expired - Lifetime
- 2004-08-16 PT PT04801986T patent/PT1654387E/pt unknown
- 2004-08-16 ES ES04801986T patent/ES2325445T3/es not_active Expired - Lifetime
- 2004-08-16 AT AT09159214T patent/ATE510931T1/de active
- 2004-08-16 EP EP09165293.3A patent/EP2112232B1/de not_active Expired - Lifetime
- 2004-08-16 AT AT04801986T patent/ATE430812T1/de active
- 2004-08-16 AU AU2004269340A patent/AU2004269340B2/en not_active Ceased
- 2004-08-16 EP EP04801986A patent/EP1654387B1/de not_active Expired - Lifetime
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2005
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2006
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2013
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