ATE43139T1 - Klonierungs- und expressionsvektoren fuer gammainterferon, transformierte bakterien und verfahren zur herstellung von gamma-interferon. - Google Patents

Klonierungs- und expressionsvektoren fuer gammainterferon, transformierte bakterien und verfahren zur herstellung von gamma-interferon.

Info

Publication number
ATE43139T1
ATE43139T1 AT84402502T AT84402502T ATE43139T1 AT E43139 T1 ATE43139 T1 AT E43139T1 AT 84402502 T AT84402502 T AT 84402502T AT 84402502 T AT84402502 T AT 84402502T AT E43139 T1 ATE43139 T1 AT E43139T1
Authority
AT
Austria
Prior art keywords
gamma interferon
cloning
methods
expression vectors
transformed bacteria
Prior art date
Application number
AT84402502T
Other languages
English (en)
Inventor
Paul Sondermeyer
Michael Courtney
Luc-Henri Tessier
Jean Pierre Lecocq
Original Assignee
Transgene Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transgene Sa filed Critical Transgene Sa
Application granted granted Critical
Publication of ATE43139T1 publication Critical patent/ATE43139T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/73—Expression systems using phage (lambda) regulatory sequences

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT84402502T 1983-12-09 1984-12-05 Klonierungs- und expressionsvektoren fuer gammainterferon, transformierte bakterien und verfahren zur herstellung von gamma-interferon. ATE43139T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8319777A FR2556365B1 (fr) 1983-12-09 1983-12-09 Vecteurs de clonage et d'expression de l'interferon-g, bacteries transformees et procede de preparation de l'interferon-g
EP84402502A EP0146462B1 (de) 1983-12-09 1984-12-05 Klonierungs- und Expressionsvektoren für gamma-Interferon, transformierte Bakterien und Verfahren zur Herstellung von gamma-Interferon

Publications (1)

Publication Number Publication Date
ATE43139T1 true ATE43139T1 (de) 1989-06-15

Family

ID=9295048

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84402502T ATE43139T1 (de) 1983-12-09 1984-12-05 Klonierungs- und expressionsvektoren fuer gammainterferon, transformierte bakterien und verfahren zur herstellung von gamma-interferon.

Country Status (8)

Country Link
US (1) US5081022A (de)
EP (1) EP0146462B1 (de)
JP (1) JPS61500588A (de)
AT (1) ATE43139T1 (de)
CA (1) CA1245584A (de)
DE (1) DE3478230D1 (de)
FR (1) FR2556365B1 (de)
WO (1) WO1985002624A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4855238A (en) 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor
FR2598430B1 (fr) * 1986-05-06 1990-02-02 Roussel Uclaf Nouveaux vecteurs d'expression, leur procede d'obtention et leur application pour exprimer une proteine quelconque dans escherichia coli
ATE129285T1 (de) * 1986-08-05 1995-11-15 Transgene Sa Verfahren zur stabilisierung eines plasmids, das in einem bakterienstamm enthalten ist und der erhaltene stamm.
JPH07163368A (ja) * 1993-12-15 1995-06-27 Hayashibara Biochem Lab Inc 組換えｄｎａとその組換えｄｎａを含む形質転換体
DK1368483T3 (da) 2001-03-09 2012-11-05 Genentech Inc Fremgangsmåde til fremstilling af polypeptider
US8778880B2 (en) 2004-02-02 2014-07-15 Ambrx, Inc. Human growth hormone modified at position 35
AU2008201682B2 (en) * 2004-02-02 2011-02-24 Ambrx, Inc. Modified human interferon polypeptides and their uses
CA2663986C (en) * 2006-09-21 2013-06-25 Asahi Kasei Chemicals Corporation Wastewater treatment method

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE63126B1 (en) * 1980-06-06 1995-03-22 Biogen Inc Improved vectors and methods for making such vectors and for expressing cloned genes
AU561343B2 (en) * 1981-10-19 1987-05-07 Genentech Inc. Human immune interferon by recombinant dna
IL68100A0 (en) * 1982-03-24 1983-06-15 Takeda Chemical Industries Ltd Novel dna and use thereof
US6936694B1 (en) * 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
FR2526661B1 (fr) * 1982-05-13 1986-02-21 Transgene Sa Nouveaux vecteurs d'expression de la proteine antigenique de la rage et leur application a la preparation de vaccins
JPH0787797B2 (ja) * 1982-05-20 1995-09-27 サントリー株式会社 ヒト・ガンマ・インタ−フエロン様ポリペプチドの製造法
US4582800A (en) * 1982-07-12 1986-04-15 Hoffmann-La Roche Inc. Novel vectors and method for controlling interferon expression
WO1984002129A1 (fr) * 1982-11-22 1984-06-07 Takeda Chemical Industries Ltd Proteine de l'interferon immun humain et son procede de preparation
US4578355A (en) * 1983-01-12 1986-03-25 The United States Of America As Represented By The Department Of Health And Human Services Plasmid cloning vector pAS1

Also Published As

Publication number Publication date
EP0146462A3 (en) 1985-08-14
FR2556365A1 (fr) 1985-06-14
EP0146462B1 (de) 1989-05-17
DE3478230D1 (en) 1989-06-22
CA1245584A (fr) 1988-11-29
WO1985002624A1 (fr) 1985-06-20
JPS61500588A (ja) 1986-04-03
FR2556365B1 (fr) 1987-07-31
EP0146462A2 (de) 1985-06-26
US5081022A (en) 1992-01-14

Similar Documents

Publication Publication Date Title
EG19101A (en) Process for preparing of expression of human proapolipoprotein A.1.
EP0722461A4 (de) Expression eines fusionspolypeptides, das ohne leadersequenz aus dem cytoplasma transportiert wird
ATE54167T1 (de) Promotoren fuer die expression von fremden genen in hefe, plasmide, die diese promotoren enthalten, sowie deren verwendung zur herstellung von polypeptiden.
ATE192500T1 (de) Rekombinante viren vektoren zur expression in muskelzellen
DE3177106D1 (en) Hybrid human leukocyte interferons, process for their microbial production, intermediates therefor and compositions containing them
ATE43635T1 (de) Verfahren zur herstellung von interferon und expressionsvektoren dafuer.
ES2181674T3 (es) Dominios de union en las proteinas notch y delta.
DE3586189D1 (de) Menge und verfahren zur herstellung rekombinierter erzeugnisse in grosser ausbeute.
ATE43139T1 (de) Klonierungs- und expressionsvektoren fuer gammainterferon, transformierte bakterien und verfahren zur herstellung von gamma-interferon.
ES8107307A1 (es) Un procedimiento de preparacion de un vector de transferen- cia de adn
NZ241829A (en) Oxalate oxidase, genes encoding it, vectors and transformed plants
ATE166390T1 (de) Anti-katze immundefiziensvirus (fiv) impfstoffe
EP0072541A3 (de) Menschliche Leukozyten-Interferone, Verfahren zu deren Mikrobiologischer Herstellung, Zwischenprodukte und diese enthaltende Zusammensetzungen
ATE233321T1 (de) Verbesserungen in der herstellung von proteinen in wirtszellen
JPS5756495A (en) Novel dna-introduction vector and recombinant dna
DE69031996D1 (de) Menschlicher rekombinanter plazentaler ribonuklease-inhibitor und verfahren zur herstellung

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee