ATE432978T1 - T-zellaktivierung - Google Patents

T-zellaktivierung

Info

Publication number: ATE432978T1
Authority: AT; Austria
Prior art keywords: cell activation; interleukin; cells; cytokines; contacting
Prior art date: 1994-08-17

Application number

AT95927917T

Other languages

English (en)

Inventor

Sergio Abrignani

Original Assignee

Novartis Vaccines & Diagnostic

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-08-17

Filing date

1995-08-17

Publication date

2009-06-15

1995-08-17 Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic

2009-06-15 Application granted granted Critical

2009-06-15 Publication of ATE432978T1 publication Critical patent/ATE432978T1/de

Links

230000006044 T cell activation Effects 0.000 title 1
210000001744 T-lymphocyte Anatomy 0.000 abstract 2
102000004127 Cytokines Human genes 0.000 abstract 1
108090000695 Cytokines Proteins 0.000 abstract 1
102000000588 Interleukin-2 Human genes 0.000 abstract 1
108010002350 Interleukin-2 Proteins 0.000 abstract 1
102000004889 Interleukin-6 Human genes 0.000 abstract 1
108090001005 Interleukin-6 Proteins 0.000 abstract 1
108060008682 Tumor Necrosis Factor Proteins 0.000 abstract 1
102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 abstract 1
230000004913 activation Effects 0.000 abstract 1
239000000427 antigen Substances 0.000 abstract 1
102000036639 antigens Human genes 0.000 abstract 1
108091007433 antigens Proteins 0.000 abstract 1
229940100601 interleukin-6 Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2013—IL-2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/25—Tumour necrosing factors [TNF]

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Virology (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Biophysics (AREA)
Hematology (AREA)
Tropical Medicine & Parasitology (AREA)
Toxicology (AREA)
Cell Biology (AREA)
Microbiology (AREA)
General Engineering & Computer Science (AREA)
AIDS & HIV (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT95927917T 1994-08-17 1995-08-17 T-zellaktivierung ATE432978T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB9416657A GB9416657D0 (en)	1994-08-17	1994-08-17	T cell activation
PCT/IB1995/000691 WO1996005288A2 (en)	1994-08-17	1995-08-17	T cell activation

Publications (1)

Publication Number	Publication Date
ATE432978T1 true ATE432978T1 (de)	2009-06-15

Family

ID=10760006

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95927917T ATE432978T1 (de)	1994-08-17	1995-08-17	T-zellaktivierung

Country Status (8)

Country	Link
US (3)	US6074635A (de)
EP (1)	EP0772677B1 (de)
JP (3)	JP3761574B2 (de)
AT (1)	ATE432978T1 (de)
CA (1)	CA2197801A1 (de)
DE (1)	DE69535961D1 (de)
GB (1)	GB9416657D0 (de)
WO (1)	WO1996005288A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9416657D0 (en) *	1994-08-17	1994-10-12	Biocine Spa	T cell activation
EP1032651B1 (de) *	1997-10-23	2006-08-16	Vlaams Interuniversitair Instituut voor Biotechnologie vzw.	Induzierte zelluläre immunitität durch aktivierung der th1 und unterdrückung der th2 antwort durch macrophhagen
CN1217698C (zh) *	1998-08-24	2005-09-07	马克西姆药品公司	应用h2受体激动剂和其它t细胞活化剂激活和保护t细胞(cd4+和cd8+)
US20030069968A1 (en) *	1998-10-01	2003-04-10	O'neil Kevin M.	System for balancing loads among network servers
US7572631B2 (en)	2000-02-24	2009-08-11	Invitrogen Corporation	Activation and expansion of T cells
US7541184B2 (en) *	2000-02-24	2009-06-02	Invitrogen Corporation	Activation and expansion of cells
EP1401495A4 (de) *	2001-06-01	2005-11-23	Xcyte Therapies Inc	T-zelleninduzierte gewebereparatur und regeneration
US20050226857A1 (en) *	2001-06-01	2005-10-13	Xcyte Therapies, Inc.	T cell therapy for the treatment of cachexia and chronic diseases
IL149820A0 (en) *	2002-05-23	2002-11-10	Curetech Ltd	Humanized immunomodulatory monoclonal antibodies for the treatment of neoplastic disease or immunodeficiency
DK1623017T3 (da) *	2003-05-08	2011-01-10	Life Technologies Corp	Frembringelse og isolering af antigenspecifikke T-celler
CA2539716A1 (en) *	2003-09-22	2005-04-07	Xcyte Therapies, Inc.	Compositions and methods to accelerate hematologic recovery
DE102004034236A1 (de) *	2004-07-15	2006-02-16	Federal-Mogul Sealing Systems Bretten Gmbh	Dichtung mit Träger und deren Herstellung
US20090123413A1 (en) *	2004-08-23	2009-05-14	Britta Hardy	Use of bat monoclonal antibody for immunotherapy
US9580504B1 (en)	2013-11-07	2017-02-28	Curetech Ltd.	Pidilizumab monoclonal antibody therapy following stem cell transplantation
CN104830768B (zh) *	2015-05-07	2017-12-26	中山大学	阿普洛尔对中央记忆性t细胞体外扩增中的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4411992A (en) *	1981-04-14	1983-10-25	Immunex Corporation	Process for preparing murine interleukin 2
US5766920A (en) *	1982-08-11	1998-06-16	Cellcor, Inc.	Ex vivo activation of immune cells
US5425940A (en) *	1986-04-09	1995-06-20	Cetus Oncology Corporation	Combination therapy using interleukin-2 and tumor necrosis factor
US4879111A (en) *	1986-04-17	1989-11-07	Cetus Corporation	Treatment of infections with lymphokines
US6348191B1 (en) *	1986-07-08	2002-02-19	Genetics Institute, Inc.	Production and use of IL-6
EP0303483A3 (de) *	1987-08-14	1989-06-07	The University Of British Columbia	Lymphokin und dessen Zusammensetzungen
AU3183089A (en) *	1988-02-11	1989-09-06	Board Of Regents, The University Of Texas System	Improved method for treatment of cancer with activated oncolytic leukocytes
JPH0296598A (ja) *	1988-10-03	1990-04-09	Sapporo Breweries Ltd	リンフォカイン活性化キラー細胞誘導抑制因子ｌａｋｓｆ，その製造法およびそれを有効成分とする免疫抑制剤
GB9416657D0 (en) *	1994-08-17	1994-10-12	Biocine Spa	T cell activation

1994
- 1994-08-17 GB GB9416657A patent/GB9416657D0/en active Pending
1995
- 1995-08-17 EP EP95927917A patent/EP0772677B1/de not_active Expired - Lifetime
- 1995-08-17 JP JP50716796A patent/JP3761574B2/ja not_active Expired - Lifetime
- 1995-08-17 WO PCT/IB1995/000691 patent/WO1996005288A2/en not_active Ceased
- 1995-08-17 CA CA002197801A patent/CA2197801A1/en not_active Abandoned
- 1995-08-17 US US08/776,259 patent/US6074635A/en not_active Expired - Lifetime
- 1995-08-17 DE DE69535961T patent/DE69535961D1/de not_active Expired - Lifetime
- 1995-08-17 AT AT95927917T patent/ATE432978T1/de active
2004
- 2004-07-28 JP JP2004220905A patent/JP2005185275A/ja not_active Withdrawn
2005
- 2005-07-19 US US11/185,273 patent/US20050281793A1/en not_active Abandoned
2006
- 2006-06-29 JP JP2006180501A patent/JP2006312640A/ja not_active Withdrawn
2009
- 2009-11-24 US US12/592,531 patent/US20100143293A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CA2197801A1 (en)	1996-02-22
JP3761574B2 (ja)	2006-03-29
US6074635A (en)	2000-06-13
US20100143293A1 (en)	2010-06-10
WO1996005288A2 (en)	1996-02-22
JP2006312640A (ja)	2006-11-16
JP2005185275A (ja)	2005-07-14
DE69535961D1 (de)	2009-07-16
EP0772677B1 (de)	2009-06-03
JPH10504194A (ja)	1998-04-28
EP0772677A1 (de)	1997-05-14
GB9416657D0 (en)	1994-10-12
WO1996005288A3 (en)	1996-04-18
US20050281793A1 (en)	2005-12-22

Legal Events

Date

Code

Title

Description

2009-12-15

UEP

Publication of translation of european patent specification

Ref document number: 0772677

Country of ref document: EP

Publication	Publication Date	Title
ATE432978T1 (de)	2009-06-15	T-zellaktivierung
PT1666585E (pt)	2008-12-10	Células secretoras macroencapsuladas
NO972455L (no)	1997-08-06	Cytokin betegnet LERK-7
NO20001583D0 (no)	2000-03-27	Stimulering av hematopoetiske celler in vitro
ES2088858T3 (es)	1996-10-01	Proteina interleuquina-4 que tiene actividad de factor de crecimiento de celulas b(bcgf) y de factor de crecimiento de celulas t(tcgf) en celulas humanas (interleuquina-4 humana).
ES2182906T3 (es)	2003-03-16	Grapa quirurgica helicoidal.
MX9301753A (es)	1993-09-01	Generacion in vitro de celulas dentriticas humanas y utilizacion de las mismas.
DK0650512T3 (da)	2001-12-03	Aldehyd-hærdet klæbemiddel på grundlag af protein
DE69736669D1 (de)	2006-10-26	Zelladhäsionsinhibitoren
DE3780316D1 (de)	1992-08-13	Verwendung von interleukin-1 zur induzierung der bildung von multipotenten haemopoietischen zellpopulationen.
FI896093A0 (fi)	1989-12-19	Varmlaminerbara, gas ogenomslaeppliga flerskiktsfolier.
DE68908335D1 (de)	1993-09-16	Epitaxiereaktor mit einem verbesserten gassammler.
FI874106A7 (fi)	1988-03-26	Tasausvastus suurpaineisille natriumlampuille, joilla on vakio linja- ja lampputeho.
NO910982L (no)	1991-05-10	Uratoksydase-aktivt protein, rekombinant gen som koder for det, ekspresjonsvektor, mikroorganismer og transformerteceller.
IT8520326A0 (it)	1985-04-12	Complesso valvolare e apparato di modulazione di compressori.
DE3483822D1 (de)	1991-02-07	Polyhydroxybenzoesaeure-abkoemmlinge.
DE3668093D1 (de)	1990-02-08	Hochdruckentladungslampe.
DE3765240D1 (de)	1990-10-31	Hochdruckgasentladungslampe.
DE3670401D1 (de)	1990-05-17	Hochdruckentladungslampe.
DE3686193D1 (de)	1992-09-03	Natriumhochdruckentladungslampe mit getter.
ES8306506A1 (es)	1983-06-01	Procedimiento para la obtencion de un antibiotico tipo s 41062
ES547331A0 (es)	1987-04-01	Procedimiento para calcinar cuerpos carbonosos, en particular electrodos.
DE3886495D1 (de)	1994-02-03	Gaslaser, insbesondere Hochleistungslaser.
DE3580998D1 (de)	1991-02-07	Hochdruckentladungslampe.
DE3585367D1 (de)	1992-03-19	Hochfrequenzenergiequelle.