ATE434448T1 - Zusammensetzungen und verfahren zur verstärkung der verabreichung von therapeutischen mitteln in zellen - Google Patents

Zusammensetzungen und verfahren zur verstärkung der verabreichung von therapeutischen mitteln in zellen

Info

Publication number
ATE434448T1
ATE434448T1 AT98934359T AT98934359T ATE434448T1 AT E434448 T1 ATE434448 T1 AT E434448T1 AT 98934359 T AT98934359 T AT 98934359T AT 98934359 T AT98934359 T AT 98934359T AT E434448 T1 ATE434448 T1 AT E434448T1
Authority
AT
Austria
Prior art keywords
compositions
cells
methods
therapeutic agents
enhanced delivery
Prior art date
Application number
AT98934359T
Other languages
English (en)
Inventor
Heidrun Engler
Tattanahalli Nagabhushan
Stephen Youngster
Original Assignee
Canji Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Canji Inc filed Critical Canji Inc
Application granted granted Critical
Publication of ATE434448T1 publication Critical patent/ATE434448T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
AT98934359T 1997-07-08 1998-07-08 Zusammensetzungen und verfahren zur verstärkung der verabreichung von therapeutischen mitteln in zellen ATE434448T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/889,355 US7002027B1 (en) 1996-01-08 1997-07-08 Compositions and methods for therapeutic use
PCT/US1998/014241 WO1999002191A1 (en) 1997-07-08 1998-07-08 Compositions and methods for enhancing delivery of therapeutic agents to cells

Publications (1)

Publication Number Publication Date
ATE434448T1 true ATE434448T1 (de) 2009-07-15

Family

ID=25394956

Family Applications (2)

Application Number Title Priority Date Filing Date
AT09008139T ATE497786T1 (de) 1997-07-08 1998-07-08 Zusammensetzungen und kits zur erhöhung der abgabe von therapeutischen mitteln an zellen
AT98934359T ATE434448T1 (de) 1997-07-08 1998-07-08 Zusammensetzungen und verfahren zur verstärkung der verabreichung von therapeutischen mitteln in zellen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT09008139T ATE497786T1 (de) 1997-07-08 1998-07-08 Zusammensetzungen und kits zur erhöhung der abgabe von therapeutischen mitteln an zellen

Country Status (20)

Country Link
US (3) US7002027B1 (de)
EP (2) EP1011733B1 (de)
JP (2) JP4460148B2 (de)
KR (1) KR100691572B1 (de)
AR (1) AR016312A1 (de)
AT (2) ATE497786T1 (de)
AU (1) AU774338B2 (de)
CA (1) CA2294709C (de)
CY (1) CY1109367T1 (de)
DE (2) DE69842133D1 (de)
DK (1) DK1011733T3 (de)
ES (2) ES2362027T3 (de)
HU (1) HUP0002683A3 (de)
IL (1) IL133929A0 (de)
MY (1) MY138257A (de)
NZ (1) NZ502060A (de)
PT (1) PT1011733E (de)
TW (1) TW490306B (de)
WO (1) WO1999002191A1 (de)
ZA (1) ZA986003B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5789244A (en) * 1996-01-08 1998-08-04 Canji, Inc. Compositions and methods for the treatment of cancer using recombinant viral vector delivery systems
US7002027B1 (en) * 1996-01-08 2006-02-21 Canji, Inc. Compositions and methods for therapeutic use
US20040014709A1 (en) * 1996-01-08 2004-01-22 Canji, Inc. Methods and compositions for interferon therapy
US6392069B2 (en) * 1996-01-08 2002-05-21 Canji, Inc. Compositions for enhancing delivery of nucleic acids to cells
AU768542C (en) 1998-04-08 2004-06-17 Celltech R & D Limited Lipids
TR201910060T4 (tr) * 2001-12-20 2019-07-22 Merck Sharp & Dohme SYN3 bileşimleri ve yöntemleri.
WO2004108088A2 (en) * 2003-06-04 2004-12-16 Canji, Inc. Methods and compositions for interferon therapy
US7355056B2 (en) * 2003-06-04 2008-04-08 Canji, Inc. Transfection agents
US7790039B2 (en) * 2003-11-24 2010-09-07 Northwest Biotherapeutics, Inc. Tangential flow filtration devices and methods for stem cell enrichment
US7691822B2 (en) * 2003-12-10 2010-04-06 Canji, Inc. Methods and compositions for treatment of interferon-resistant tumors
US20060127468A1 (en) 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening
WO2007030588A1 (en) * 2005-09-07 2007-03-15 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Use of replicators to prevent gene silencing
WO2009136396A2 (en) * 2008-05-05 2009-11-12 Tiltan Pharma Ltd. Sulfobetaines for therapy
US8101593B2 (en) 2009-03-03 2012-01-24 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
DK3252068T3 (da) 2009-10-12 2025-08-25 Larry J Smith Metoder og sammensætninger til modulering af genekspression ved anvendelse af oligonukleotidbaserede lægemidler administreret in vivo eller in vitro
US20120147800A1 (en) * 2010-12-10 2012-06-14 Minyoung Park Power management in a wireless network having stations with different power capabilities
CA2827643C (en) 2011-02-18 2019-05-07 Kythera Biopharmaceuticals, Inc. Treatment of submental fat
US8653058B2 (en) 2011-04-05 2014-02-18 Kythera Biopharmaceuticals, Inc. Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits
US10492104B2 (en) * 2016-03-10 2019-11-26 Cable Television Laboratories, Inc. Latency reduction in wireless service
WO2026077967A1 (en) 2024-10-08 2026-04-16 Ferring International Center Sa Method for making syn3

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5554386A (en) 1986-07-03 1996-09-10 Advanced Magnetics, Inc. Delivery of therapeutic agents to receptors using polysaccharides
US5166320A (en) 1987-04-22 1992-11-24 University Of Connecticut Carrier system and method for the introduction of genes into mammalian cells
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5108921A (en) 1989-04-03 1992-04-28 Purdue Research Foundation Method for enhanced transmembrane transport of exogenous molecules
US6207454B1 (en) 1989-10-16 2001-03-27 Amgen Inc. Method for enhancing the effciency of gene transfer with stem cell factor (SCF) polypeptide
US5013556A (en) 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5542935A (en) 1989-12-22 1996-08-06 Imarx Pharmaceutical Corp. Therapeutic delivery systems related applications
US5279833A (en) 1990-04-04 1994-01-18 Yale University Liposomal transfection of nucleic acids into animal cells
US5264618A (en) * 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
US5120316A (en) 1990-09-28 1992-06-09 Akzo N.V. Urethral catheter and catheterization process
CA2092323A1 (en) 1990-10-01 1992-04-02 George Y. Wu Targeting viruses and cells for selective internalization by cells
NZ240846A (en) * 1990-12-06 1994-04-27 Hoechst Ag Dimeric bile acid derivatives; preparatory processes and pharmaceutical compositions
DE69233725T2 (de) 1991-06-28 2009-02-12 The Regents Of The University Of Michigan, Ann Arbor Verwendung von DNA oder RNA zur Herstellung eines Medikaments zur Behandlung von Tumoren
EP0659209A1 (de) 1991-07-26 1995-06-28 The University Of Rochester Krebstherapie unter verwendung maligner zellen
US5283185A (en) 1991-08-28 1994-02-01 University Of Tennessee Research Corporation Method for delivering nucleic acids into cells
US5521291A (en) 1991-09-30 1996-05-28 Boehringer Ingelheim International, Gmbh Conjugates for introducing nucleic acid into higher eucaryotic cells
US6013638A (en) 1991-10-02 2000-01-11 The United States Of America As Represented By The Department Of Health And Human Services Adenovirus comprising deletions on the E1A, E1B and E3 regions for transfer of genes to the lung
US5795870A (en) * 1991-12-13 1998-08-18 Trustees Of Princeton University Compositions and methods for cell transformation
WO1993014188A1 (en) 1992-01-17 1993-07-22 The Regents Of The University Of Michigan Targeted virus
US5602023A (en) 1992-03-24 1997-02-11 Csatary; Laszlo K. Pharmaceutical product containing live, stabilized virus for the therapy of viral and malignant diseases and process for preparing the same
CA2133411A1 (en) 1992-04-03 1993-10-14 Alexander T. YOUNG Gene therapy using targeted viral vectors
DE69333434T2 (de) 1992-04-03 2005-03-03 The Regents Of The University Of California, Oakland Selbstorganisierendes system zur verabreichung von polynukleotiden enthaltend ein amphiphatisches peptid
US5334761A (en) 1992-08-28 1994-08-02 Life Technologies, Inc. Cationic lipids
US5656609A (en) 1992-09-24 1997-08-12 University Of Connecticut Method of enhancing and/or prolonging expression of gene introduced into a cell using colchicine
WO1994006923A1 (en) 1992-09-24 1994-03-31 The University Of Connecticut Modification of a virus to redirect infectivity and enhance targeted delivery of polynucleotides to cells
US5346701A (en) 1993-02-22 1994-09-13 Theratech, Inc. Transmucosal delivery of macromolecular drugs
US5578475A (en) 1993-07-12 1996-11-26 Life Technologies, Inc. Composition and methods for transfecting eukaryotic cells
US5804566A (en) * 1993-08-26 1998-09-08 The Regents Of The University Of California Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides
US5631236A (en) 1993-08-26 1997-05-20 Baylor College Of Medicine Gene therapy for solid tumors, using a DNA sequence encoding HSV-Tk or VZV-Tk
JPH07109983A (ja) 1993-10-13 1995-04-25 Nippondenso Co Ltd スクロール型圧縮機
KR100218140B1 (ko) 1993-10-15 1999-09-01 잭 제이 루치이스 치료학적 전달 조성물 및 그의 사용 방법
US6210939B1 (en) 1993-10-25 2001-04-03 Canji, Inc. Recombinant adenoviral vector and methods of use
DE69434594T2 (de) 1993-10-25 2006-09-21 Canji, Inc., San Diego Rekombinante adenoviren-vektor und verfahren zur verwendung
US5837533A (en) * 1994-09-28 1998-11-17 American Home Products Corporation Complexes comprising a nucleic acid bound to a cationic polyamine having an endosome disruption agent
US5552309A (en) 1994-09-30 1996-09-03 Indiana University Foundation Use of polyols for improving the introduction of genetic material into cells
US7163925B1 (en) 1995-07-17 2007-01-16 Board Of Regents, The University Of Texas System p16 expression constructs and their application in cancer therapy
WO1997005209A1 (en) * 1995-07-28 1997-02-13 Kohne David E Method for enhancing chemiluminescence
US5789244A (en) 1996-01-08 1998-08-04 Canji, Inc. Compositions and methods for the treatment of cancer using recombinant viral vector delivery systems
US7002027B1 (en) 1996-01-08 2006-02-21 Canji, Inc. Compositions and methods for therapeutic use
US20040014709A1 (en) 1996-01-08 2004-01-22 Canji, Inc. Methods and compositions for interferon therapy
US6392069B2 (en) 1996-01-08 2002-05-21 Canji, Inc. Compositions for enhancing delivery of nucleic acids to cells
US5671110A (en) 1996-01-23 1997-09-23 Oneac Corporation Ground skew protection method and apparatus
US6283940B1 (en) * 1997-08-29 2001-09-04 S. Grant Mulholland Catheter
US6938069B1 (en) * 2000-03-18 2005-08-30 Computing Services Support Solutions Electronic meeting center
TR201910060T4 (tr) 2001-12-20 2019-07-22 Merck Sharp & Dohme SYN3 bileşimleri ve yöntemleri.
KR100499787B1 (ko) 2002-11-29 2005-07-07 인티그런트 테크놀로지즈(주) 스위치 모드 동작을 하는 선형성이 우수한 광대역 가변이득 증폭기
US7355056B2 (en) 2003-06-04 2008-04-08 Canji, Inc. Transfection agents
WO2004108898A2 (en) 2003-06-04 2004-12-16 Canji, Inc. Transfection agents
WO2004108088A2 (en) 2003-06-04 2004-12-16 Canji, Inc. Methods and compositions for interferon therapy
US7691822B2 (en) 2003-12-10 2010-04-06 Canji, Inc. Methods and compositions for treatment of interferon-resistant tumors

Also Published As

Publication number Publication date
JP2001509492A (ja) 2001-07-24
ATE497786T1 (de) 2011-02-15
JP4460148B2 (ja) 2010-05-12
EP1011733A1 (de) 2000-06-28
JP2010070565A (ja) 2010-04-02
DE69842133D1 (de) 2011-03-24
US20100028431A1 (en) 2010-02-04
ES2328094T3 (es) 2009-11-06
DK1011733T3 (da) 2009-09-28
DE69840932D1 (de) 2009-08-06
US7538093B2 (en) 2009-05-26
TW490306B (en) 2002-06-11
NZ502060A (en) 2003-01-31
AU8390198A (en) 1999-02-08
KR20010021620A (ko) 2001-03-15
PT1011733E (pt) 2009-09-15
US7002027B1 (en) 2006-02-21
IL133929A0 (en) 2001-04-30
AU774338B2 (en) 2004-06-24
AR016312A1 (es) 2001-07-04
EP2106807B1 (de) 2011-02-09
WO1999002191A1 (en) 1999-01-21
EP1011733A4 (de) 2004-09-29
EP2106807A1 (de) 2009-10-07
HK1028961A1 (en) 2001-03-16
HK1134025A1 (en) 2010-04-16
CA2294709C (en) 2010-05-11
EP1011733B1 (de) 2009-06-24
ES2362027T3 (es) 2011-06-27
KR100691572B1 (ko) 2007-03-12
HUP0002683A3 (en) 2005-09-28
HUP0002683A2 (hu) 2000-12-28
ZA986003B (en) 1999-01-28
MY138257A (en) 2009-05-29
CY1109367T1 (el) 2014-07-02
US20060199782A1 (en) 2006-09-07
US8022044B2 (en) 2011-09-20
CA2294709A1 (en) 1999-01-21

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