ATE435646T1 - Perfluorkohlenstoffe als entzündungshemmendes mittel - Google Patents

Perfluorkohlenstoffe als entzündungshemmendes mittel

Info

Publication number
ATE435646T1
ATE435646T1 AT94929390T AT94929390T ATE435646T1 AT E435646 T1 ATE435646 T1 AT E435646T1 AT 94929390 T AT94929390 T AT 94929390T AT 94929390 T AT94929390 T AT 94929390T AT E435646 T1 ATE435646 T1 AT E435646T1
Authority
AT
Austria
Prior art keywords
perfluorocarbons
inflammatory agent
tissue
reducing
inflammation
Prior art date
Application number
AT94929390T
Other languages
English (en)
Inventor
Bradley Fuhrman
Stephen Flaim
Lynn Hernan
Frances Nesti
Michele Cecile Papo
David Steinhorn
Original Assignee
Univ New York State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York State Res Found filed Critical Univ New York State Res Found
Application granted granted Critical
Publication of ATE435646T1 publication Critical patent/ATE435646T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT94929390T 1993-09-29 1994-09-29 Perfluorkohlenstoffe als entzündungshemmendes mittel ATE435646T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/128,811 US5470885A (en) 1993-09-29 1993-09-29 Fluorocarbons as anti-inflammatory agents
PCT/US1994/011092 WO1995008985A1 (en) 1993-09-29 1994-09-29 Perfluorocarbons as anti-inflammatory agents

Publications (1)

Publication Number Publication Date
ATE435646T1 true ATE435646T1 (de) 2009-07-15

Family

ID=22437089

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94929390T ATE435646T1 (de) 1993-09-29 1994-09-29 Perfluorkohlenstoffe als entzündungshemmendes mittel

Country Status (8)

Country Link
US (2) US5470885A (de)
EP (1) EP0738142B1 (de)
JP (1) JPH09503211A (de)
AT (1) ATE435646T1 (de)
AU (1) AU691837B2 (de)
CA (1) CA2172601A1 (de)
DE (1) DE69435215D1 (de)
WO (1) WO1995008985A1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE173920T1 (de) * 1991-05-03 1998-12-15 Alliance Pharma Partielle flüssigkeitsbeatmung mittels fluorkohlenwasserstoffen
US5470885A (en) * 1993-09-29 1995-11-28 The Research Foundation Of The State University Of New York Fluorocarbons as anti-inflammatory agents
US5861175A (en) 1996-03-15 1999-01-19 Alliance Pharmaceutical Corp. Use of fluorocarbons for diagnosis and treatment of articular disorders
AU4093097A (en) * 1996-10-15 1998-05-11 Sonus Pharmaceuticals, Inc. Fluorocarbon-containing agents for pulmonary lavage and drug delivery
SE507617C2 (sv) * 1996-12-20 1998-06-29 Siemens Elema Ab Anordning avsedd att användas vid ett behandlingssystem för respiratorvård med vätska
US20060025348A1 (en) * 1997-05-28 2006-02-02 Pilon Aprile L Methods and compositions for the treatment of fibrotic conditions & impaired lung function & to enhance lymphocyte production
US6255281B1 (en) * 1997-05-28 2001-07-03 Claragen, Inc. And U.S. Government Use of recombinant human uteroglobin in treatment of inflammatory and fibrotic conditions
US20060281681A1 (en) * 1997-05-28 2006-12-14 Pilon Aprile L Methods and compositions for the reduction of neutrophil influx and for the treatment of bronchpulmonary dysplasia, respiratory distress syndrome, chronic lung disease, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease
US6433040B1 (en) * 1997-09-29 2002-08-13 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6946117B1 (en) 1997-09-29 2005-09-20 Nektar Therapeutics Stabilized preparations for use in nebulizers
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
DE19823606C2 (de) * 1998-05-27 2002-02-28 Draeger Medical Ag Verwendung von Perfluorcarbone in einem Atemgasgemisch sowie die Vorrichtung
US6894079B1 (en) 1998-12-01 2005-05-17 Alexandre T. Rotta Method for reducing free-radical induced injury
ES2160534B1 (es) * 1999-12-30 2002-04-16 Vita Invest Sa Nuevos esteres derivados de (rr,ss)-2-hidroxibenzoato de 3-(2-dimetilaminometil-1-hidroxiciclohexil) fenilo.
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
PT1280520E (pt) 2000-05-10 2014-12-16 Novartis Ag Pós à base de fosfolípidos para administração de fármacos
US6235796B1 (en) * 2000-06-26 2001-05-22 Sarfaraz K. Niazi Use of fluorocarbons for the prevention of surgical adhesions
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
PT1458360E (pt) 2001-12-19 2011-07-13 Novartis Ag Derivados de indole como agonistas do recetor s1p1
US6899890B2 (en) * 2002-03-20 2005-05-31 Kv Pharmaceutical Company Bioadhesive drug delivery system
JP4079257B2 (ja) * 2002-10-01 2008-04-23 株式会社リコー 静電荷像現像用トナー
US20050118108A1 (en) * 2003-11-28 2005-06-02 Cowan Ada S. Pulmonary delivery of a liquid medicament aerosol
CA2789262C (en) 2005-04-28 2016-10-04 Proteus Digital Health, Inc. Pharma-informatics system
US7566743B2 (en) * 2005-11-18 2009-07-28 Mark Glazman System and method for medical treatment
DK1962869T3 (da) * 2005-12-21 2013-06-24 Solaeromed Inc Behandling af luftvejssygdomme
EP2063905B1 (de) 2006-09-18 2014-07-30 Raptor Pharmaceutical Inc Behandlungen von lebererkrankungen durch verabreichung von konjugaten aus rezeptor-assoziierten proteinen
NZ588895A (en) 2008-05-13 2012-07-27 Clarassance Inc Recombinant human CC10 (rhCC10 aka uteroglobin) and compositions thereof for use in the treatment of nasal rhinitis
TR201908314T4 (tr) 2009-02-20 2019-06-21 2 Bbb Medicines B V Glutatyon bazlı ilaç dağıtım sistemi.
KR101909711B1 (ko) 2009-05-06 2018-12-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US9168285B2 (en) 2009-10-15 2015-10-27 Therabron Therapeutics, Inc. Recombinant human CC10 protein for treatment of influenza and ebola
KR101597391B1 (ko) 2009-10-15 2016-02-24 클라라산스, 인크. 인플루엔자 치료용 재조합 사람 ｃｃ10 단백질
JP2011246396A (ja) * 2010-05-27 2011-12-08 Shiseido Co Ltd 血流促進剤および外用剤
EP2587917A4 (de) * 2010-07-01 2015-05-06 Mtm Res Llc Fluorchemische antifibroblasten-emulsionstherapien
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
US20250041332A1 (en) * 2021-09-13 2025-02-06 The Board Of Regents Of The University Of Texas System Systemic injection of superheated perfluorocarbon emulsion to improve ventilation and reduce ventilator-induced lung injury

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4044121A (en) * 1976-03-11 1977-08-23 Minnesota Mining And Manufacturing Company Hair spray containing fluorocarbon compounds as additives
US4680173A (en) * 1977-04-28 1987-07-14 Norman D. Burger Aerosol dispensing system
US4490351A (en) * 1982-03-15 1984-12-25 Children's Hospital Medical Center Methods of treating disorders of an eye with liquid perfluorocarbons
US4543202A (en) * 1984-03-23 1985-09-24 E. I. Du Pont De Nemours And Company Aerosol propellant compositions
US5192528A (en) * 1985-05-22 1993-03-09 Liposome Technology, Inc. Corticosteroid inhalation treatment method
US4865836A (en) * 1986-01-14 1989-09-12 Fluoromed Pharmaceutical, Inc. Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport
US4927623A (en) * 1986-01-14 1990-05-22 Alliance Pharmaceutical Corp. Dissolution of gas in a fluorocarbon liquid
US5284645A (en) * 1987-08-05 1994-02-08 Alliance Pharmaceutical Corp. Fluorocarbon emulsions containing amino acid based anti-inflamatory agents and buffer systems
US4987154A (en) * 1986-01-14 1991-01-22 Alliance Pharmaceutical Corp. Biocompatible, stable and concentrated fluorocarbon emulsions for contrast enhancement and oxygen transport in internal animal use
JPH01503146A (ja) * 1986-09-19 1989-10-26 ケメックス　ファーマシューティカルズ，インコーポレイティド 身体組織の治療方法および身体組織への医薬の投与方法
US4897262A (en) * 1988-03-22 1990-01-30 Playtex Jhirmack, Inc. Non-aerosol hair spray composition
US5028428A (en) * 1988-08-09 1991-07-02 Estee Lauder Inc. Anti-irritant and desensitizing compositions and methods of their use
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
US5213570A (en) * 1990-12-14 1993-05-25 Mallinckrodt Medical, Inc. System and method for oxygenation of the pericardium
US5437272A (en) * 1991-05-01 1995-08-01 Alliance Pharmaceutical Corp. Perfluorocarbon associated gas exchange
CA2109528A1 (en) * 1991-05-01 1992-11-02 Gregory A. Prince A method for treating infectious respiratory diseases
ATE173920T1 (de) * 1991-05-03 1998-12-15 Alliance Pharma Partielle flüssigkeitsbeatmung mittels fluorkohlenwasserstoffen
US5470885A (en) * 1993-09-29 1995-11-28 The Research Foundation Of The State University Of New York Fluorocarbons as anti-inflammatory agents

Also Published As

Publication number Publication date
CA2172601A1 (en) 1995-04-06
AU691837B2 (en) 1998-05-28
EP0738142A1 (de) 1996-10-23
AU7846994A (en) 1995-04-18
DE69435215D1 (de) 2009-08-20
US5470885A (en) 1995-11-28
EP0738142A4 (de) 1997-07-16
EP0738142B1 (de) 2009-07-08
US5733939A (en) 1998-03-31
JPH09503211A (ja) 1997-03-31
WO1995008985A1 (en) 1995-04-06

Similar Documents

Publication Publication Date Title
DE69435215D1 (de) Perfluorkohlenstoffe als entzündungshemmendes Mittel
EA199800667A1 (ru) Новые фенантридины
ES2173115T3 (es) Composiciones de limpieza en microemulsion y emulsion.
DK0782855T3 (da) Nimesulid til ekstern anvendelse
NO954441D0 (no) Tricyklopolyazamakrocyklofosfonsyrer, komplekser og derivater derav for anvendelse som kontrastmidler
ATE208621T1 (de) Stabilisierung der prostaglandinzusammensetzungen
DK0689426T3 (da) Terapeutisk middel til behandling af melanomer
DE69702393D1 (de) Video-rauschverminderung
ES2127558T3 (es) Agentes conservantes.
SE9303788L (sv) Biomedicinsk elektrod
ES2051461T3 (es) Medios de contraste.
DK0449099T3 (da) Hidtil ukendt retinoid heraf og anvendelser heraf til lægemidler
FR2713444B1 (fr) Composition liquide désinfectante et ses utilisations.
ATE172721T1 (de) Aminosäurederivate und ihre verwendung als enkephalinase-inhibitoren
DK0821588T3 (da) Levobupivacain og anvendelse heraf som et anæstetikum til gravide kvinder
ES2107852T3 (es) Procedimiento para la obtencion de 1,4-butanodiol.
IT1252603B (it) 2,4-diamino-6 piperidino pirimidina-3 ossido topico sul glande nel trattamento delle impotenze erettili
AR245433A1 (es) Purificacion de 2,2-dicloro-1,1,1-trifluoretano.
DK0453603T3 (da) Piroxicamholdige farmaceutiske præparater til topisk anvendelse
FR2569569B1 (fr) Exerciseur destine notamment au travail du grand ecart.
ES2143125T3 (es) Uso de copolimeros anfifilicos que contienen un monomero fluorado para impartir impermeabilidad al cuero.
ES2135535T3 (es) Derivados tiazolotriazol y tiazolodiazol con actividad fungicida.
DE69422013D1 (de) In position 10 substituierte 1,8-dihydroxy-9(10h)-anthracenon pharmazeutika
ES2121204T3 (es) Preparacion de fluoro-nucleosidos e intermedios para su uso en ella.
DE69807200D1 (de) Inklusionskomplexe in waessriger loesung

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties