ATE435871T1 - Methode zur bildung einen peptid-rezeptor komplex mit zsig33 polypeptiden. - Google Patents

Methode zur bildung einen peptid-rezeptor komplex mit zsig33 polypeptiden.

Info

Publication number
ATE435871T1
ATE435871T1 AT00982197T AT00982197T ATE435871T1 AT E435871 T1 ATE435871 T1 AT E435871T1 AT 00982197 T AT00982197 T AT 00982197T AT 00982197 T AT00982197 T AT 00982197T AT E435871 T1 ATE435871 T1 AT E435871T1
Authority
AT
Austria
Prior art keywords
forming
receptor complex
peptide receptor
zsig33 polypeptides
hormones
Prior art date
Application number
AT00982197T
Other languages
English (en)
Inventor
Paul Sheppard
Stephen Jaspers
Theresa Deisher
Paul Bishop
Darrell C Conklin
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Application granted granted Critical
Publication of ATE435871T1 publication Critical patent/ATE435871T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Transplantation (AREA)
  • Child & Adolescent Psychology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Pregnancy & Childbirth (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT00982197T 1999-11-22 2000-11-22 Methode zur bildung einen peptid-rezeptor komplex mit zsig33 polypeptiden. ATE435871T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16676599P 1999-11-22 1999-11-22
PCT/US2000/032074 WO2001038355A2 (en) 1999-11-22 2000-11-22 Method of forming a peptide-receptor complex with zsig33 and therapeutic use thereof

Publications (1)

Publication Number Publication Date
ATE435871T1 true ATE435871T1 (de) 2009-07-15

Family

ID=22604630

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00982197T ATE435871T1 (de) 1999-11-22 2000-11-22 Methode zur bildung einen peptid-rezeptor komplex mit zsig33 polypeptiden.

Country Status (8)

Country Link
US (2) US7888056B2 (de)
EP (1) EP1232175B1 (de)
JP (1) JP4800537B2 (de)
AT (1) ATE435871T1 (de)
AU (1) AU1925701A (de)
CA (1) CA2392019A1 (de)
DE (1) DE60042527D1 (de)
WO (1) WO2001038355A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1925701A (en) * 1999-11-22 2001-06-04 Zymogenetics Inc. Method of forming a peptide-receptor complex with zsig33
EP1556084A4 (de) * 2002-10-07 2006-01-11 Zymogenetics Inc Verfahren zur regulierung deskörpergewichts
DE602004012207T2 (de) 2003-10-16 2009-03-12 F. Hoffmann-La Roche Ag Fluoreszent markierte Ghrelin-Peptide
EP1524274B1 (de) * 2003-10-16 2008-03-05 F. Hoffmann-La Roche Ag Fluoreszent markierte Ghrelin-Peptide
CA2939778C (en) 2007-01-31 2019-01-29 Dana-Farber Cancer Institute, Inc. Stabilized p53 peptides and uses thereof
CA2682174C (en) 2007-03-28 2021-04-06 President And Fellows Of Harvard College Stitched polypeptides
KR20130099938A (ko) 2010-08-13 2013-09-06 에일러론 테라퓨틱스 인코포레이티드 펩티도미메틱 거대고리
CN104039342A (zh) 2011-10-18 2014-09-10 爱勒让治疗公司 拟肽大环化合物
NZ627528A (en) 2012-02-15 2016-05-27 Aileron Therapeutics Inc Peptidomimetic macrocycles
HK1205454A1 (en) 2012-02-15 2015-12-18 Aileron Therapeutics, Inc. Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
SG11201503052RA (en) 2012-11-01 2015-05-28 Aileron Therapeutics Inc Disubstituted amino acids and methods of preparation and use thereof
MX2017003797A (es) 2014-09-24 2017-06-15 Aileron Therapeutics Inc Macrociclos peptidomimeticos y usos de los mismos.
WO2016154058A1 (en) 2015-03-20 2016-09-29 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2315271C3 (de) 1973-03-27 1975-09-11 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen L- Norleucin-13-Motilin, Verfahren zu dessen Herstellung und dasselbe enthaltendes Mittel
US5006469A (en) 1988-02-09 1991-04-09 Oregon Health Sciences University Vectors and host cells expressing prepromotilin and motilin-associated peptide (MAP)
US5641670A (en) 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
US5470830A (en) 1993-08-06 1995-11-28 Ohmeda Pharmaceutical Products Division Inc. Motilin-like polypeptides that inhibit gastrointestinal motor activity
WO1997021730A1 (en) * 1995-12-13 1997-06-19 Merck & Co., Inc. Growth hormone secretagogue receptor family
US6380158B1 (en) 1997-03-24 2002-04-30 Zymogenetics, Inc. Motilin homologs
US6291653B1 (en) 1997-03-24 2001-09-18 Zymogenetics, Inc. Antibodies to motilin homologs
US6627729B1 (en) 1997-03-24 2003-09-30 Zymogenetics, Inc. TML peptides
CA2284733C (en) * 1997-03-24 2010-10-26 Zymogenetics, Inc. Motilin homologs
US6420521B1 (en) 1999-06-30 2002-07-16 Zymogenetics, Inc. Short gastrointestinal peptides
CN101693736B (zh) 1999-07-23 2020-09-11 寒川贤治 新的肽
AU1925701A (en) 1999-11-22 2001-06-04 Zymogenetics Inc. Method of forming a peptide-receptor complex with zsig33
US6897286B2 (en) 2000-05-11 2005-05-24 Zymogenetics, Inc. Zsig33-like peptides
US7392113B2 (en) * 2005-02-08 2008-06-24 Halliburton Energy Services, Inc. Systems for controlling multiple actuators

Also Published As

Publication number Publication date
JP4800537B2 (ja) 2011-10-26
US7888056B2 (en) 2011-02-15
DE60042527D1 (de) 2009-08-20
WO2001038355A2 (en) 2001-05-31
CA2392019A1 (en) 2001-05-31
US20110151480A1 (en) 2011-06-23
EP1232175A2 (de) 2002-08-21
JP2003514917A (ja) 2003-04-22
US8124356B2 (en) 2012-02-28
AU1925701A (en) 2001-06-04
US20090081168A1 (en) 2009-03-26
WO2001038355A3 (en) 2001-11-22
EP1232175B1 (de) 2009-07-08

Similar Documents

Publication Publication Date Title
DE60042527D1 (de) Methode zur bildung einen peptid-rezeptor komplex mit zsig33 polypeptiden.
DE3855536D1 (de) Rezeptoren für wachstumshormone
MX2010005966A (es) Conjugados de anticuerpo monoclonal-molecula asociada dirigidos a la proteina tirosina-cinasa 7 (ptk7).
IL173559A0 (en) Nogo receptor antagonists
DE60333201D1 (de) Verfahren zur herstellung von proteinen
ATE501170T1 (de) Verfahren zur herstellung humanisierter antikörper durch randomisierte mutagenese
IL184112A0 (en) A method for producing polypeptides or proteins in a disulfide-bridged two-chain form
MX348154B (es) Anticuerpos de enlace a il-1-beta y fragmentos de los mismos.
ATE457355T1 (de) Verfahren und dna-konstrukte zur produktion von polypeptiden mit hoher ausbeute
ATE368688T1 (de) Peptide, deren herstellung und verwendung zur bindung von immunglobulinen
DE60214400T8 (de) Verfahren zur proteinproduktion in pflanzen
DE59914490D1 (de) Ein faktor viii-polypeptid mit faktor viii:c-aktivität
DE60310385D1 (de) Sekretion von proteinen mit mehreren disulfidbindungen in bakterien und verwendungen davon
IS8339A (is) Mótlyf viðtaka NOGO
IL143558A0 (en) Method of enhancing the biological activity of ligands
ATE216723T1 (de) Hormones de croissance humaines mutantes et leur utilisation
IL113252A0 (en) Eph receptors binding ligands
DE60142511D1 (de) Zsig33-ähnliche peptide
BR0008187A (pt) Controle biológico de nematódeos
WO2009087173A3 (en) Antibody designated barb3, barb3 related antibodies, and methods of making and using same
TW200407428A (en) Method for the preparation of growth hormone and antagonist thereof having lower levels of isoform impurities thereof
DE60333669D1 (de) Verfahren und zusammensetzungen zur modulation und zum nachweis von wisp-aktivität
WO2005066208A3 (en) Method for production of recombinant growth hormone in form of hybrid protein
WO2004089973A3 (en) Peptides, polypeptides, and proteins of reduced immunogenicity and methods for their production
AU4567501A (en) Novel g-protein coupled receptors

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1232175

Country of ref document: EP

UEP Publication of translation of european patent specification

Ref document number: 1232175

Country of ref document: EP