ATE437370T1 - Pharmakodynamische tests mit durchflusszytometrie - Google Patents

Pharmakodynamische tests mit durchflusszytometrie

Info

Publication number
ATE437370T1
ATE437370T1 AT05723905T AT05723905T ATE437370T1 AT E437370 T1 ATE437370 T1 AT E437370T1 AT 05723905 T AT05723905 T AT 05723905T AT 05723905 T AT05723905 T AT 05723905T AT E437370 T1 ATE437370 T1 AT E437370T1
Authority
AT
Austria
Prior art keywords
flow cytometry
pharmacodynamic tests
pharmacodynamic
tests
drug
Prior art date
Application number
AT05723905T
Other languages
English (en)
Inventor
Jane Trepel
Eun Chung
Original Assignee
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv
Application granted granted Critical
Publication of ATE437370T1 publication Critical patent/ATE437370T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/44Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT05723905T 2004-02-27 2005-02-25 Pharmakodynamische tests mit durchflusszytometrie ATE437370T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54879404P 2004-02-27 2004-02-27
PCT/US2005/006236 WO2005085864A1 (en) 2004-02-27 2005-02-25 Pharmacodynamic assays using flow cytometry

Publications (1)

Publication Number Publication Date
ATE437370T1 true ATE437370T1 (de) 2009-08-15

Family

ID=34919403

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05723905T ATE437370T1 (de) 2004-02-27 2005-02-25 Pharmakodynamische tests mit durchflusszytometrie

Country Status (7)

Country Link
US (1) US9389223B2 (de)
EP (1) EP1725873B1 (de)
AT (1) ATE437370T1 (de)
AU (1) AU2005218769B8 (de)
CA (1) CA2557568C (de)
DE (1) DE602005015559D1 (de)
WO (1) WO2005085864A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602005015559D1 (de) 2004-02-27 2009-09-03 Us Gov Health & Human Serv Pharmakodynamische tests mit durchflusszytometrie
JP5156392B2 (ja) 2005-02-03 2013-03-06 トポターゲット ユーケー リミテッド Hdac阻害剤を用いる併用療法
ATE542527T1 (de) 2005-05-13 2012-02-15 Topotarget Uk Ltd Pharmazeutische formulierungen von hdac-hemmern
WO2007054719A2 (en) * 2005-11-10 2007-05-18 Topotarget Uk Limited Histone deacetylase (hdac) inhibitors (pxdlol) for the treatment of cancer alone or in combination with chemotherapeutic agent
WO2007057750A2 (en) * 2005-11-15 2007-05-24 Inverness Medical Switzerland Gmbh Assays
EP2012801A4 (de) 2006-04-24 2009-08-05 Gloucester Pharmaceuticals Inc Gemcitabin-kombinationstherapie
US8957027B2 (en) 2006-06-08 2015-02-17 Celgene Corporation Deacetylase inhibitor therapy
AU2007342028B2 (en) 2006-12-29 2013-06-13 Celgene Corporation Purifiction of romidepsin
US8642809B2 (en) * 2007-09-25 2014-02-04 Topotarget Uk Ltd. Methods of synthesis of certain hydroxamic acid compounds
ES2536208T3 (es) * 2008-03-07 2015-05-21 Onxeo Dk, Branch Of Onxeo S.A., France Métodos de tratamiento que emplean infusión continua prolongada de Belinostat
GB0900555D0 (en) * 2009-01-14 2009-02-11 Topotarget As New methods
NZ605526A (en) 2010-07-12 2015-04-24 Celgene Corp Romidepsin solid forms and uses thereof
US8859502B2 (en) 2010-09-13 2014-10-14 Celgene Corporation Therapy for MLL-rearranged leukemia
AU2013202506B2 (en) 2012-09-07 2015-06-18 Celgene Corporation Resistance biomarkers for hdac inhibitors
AU2013202507B9 (en) 2012-11-14 2015-08-13 Celgene Corporation Inhibition of drug resistant cancer cells
NZ630311A (en) 2013-12-27 2016-03-31 Celgene Corp Romidepsin formulations and uses thereof
WO2021186855A1 (ja) * 2020-03-16 2021-09-23 株式会社マンダム T細胞性リンパ腫の指標の検出方法、及びその利用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5447837A (en) * 1987-08-05 1995-09-05 Calypte, Inc. Multi-immunoassay diagnostic system for antigens or antibodies or both
US6280967B1 (en) * 1996-08-02 2001-08-28 Axiom Biotechnologies, Inc. Cell flow apparatus and method for real-time of cellular responses
WO2000011476A1 (en) * 1998-08-25 2000-03-02 The Immune Response Corporation Methods for evaluating immune function
US6841565B1 (en) * 2002-03-29 2005-01-11 The Ohio State University Treatment of patients with chronic lymphocytic leukemia
EP1403639A1 (de) * 2002-09-30 2004-03-31 G2M Cancer Drugs AG Antikörper als Diagnosemittel in der medizinischen Therapie mit Histondeacetylase-Hemmern
CA2513730A1 (en) * 2003-01-16 2004-08-05 Health Research, Inc. Method for comprehensive identification of cell lineage specific genes
CA2540260A1 (en) * 2003-09-26 2005-04-07 Janssen Pharmaceutica N.V. Analyzing histamine h4 receptor-mediated effects in whole blood
DE602005015559D1 (de) 2004-02-27 2009-09-03 Us Gov Health & Human Serv Pharmakodynamische tests mit durchflusszytometrie

Also Published As

Publication number Publication date
AU2005218769B8 (en) 2012-04-12
WO2005085864A1 (en) 2005-09-15
AU2005218769B2 (en) 2011-12-22
AU2005218769A1 (en) 2005-09-15
US9389223B2 (en) 2016-07-12
US20070054260A1 (en) 2007-03-08
EP1725873A1 (de) 2006-11-29
EP1725873B1 (de) 2009-07-22
CA2557568C (en) 2014-05-27
CA2557568A1 (en) 2005-09-15
DE602005015559D1 (de) 2009-09-03

Similar Documents

Publication Publication Date Title
ATE437370T1 (de) Pharmakodynamische tests mit durchflusszytometrie
GB2451042A (en) Reagents and methods for using human embryonic stem cells to evaluate toxicity of pharmaceutical compounds and other chemicals
IN2014DN02241A (de)
NO20065417L (no) Muskarine acetylkolinreceptorantagonister
CR8740A (es) Cartucho mecanico con caracteristicas de control fluido en tira de prueba, para utilizar en un medidor de analitos fluidos
NI200900081U (es) Anticuerpos agonistas de trkb y sus usos.
GB2474146A (en) Methods of determining the health status of an individual
CY1117282T1 (el) Διαταξη και μεθοδος ανιχνευσεως προσδιοριζομενων ουσιων
NO20062042L (no) Muskariniske acetylkolin reseptorantangonister
DE602004030054D1 (de) Untersuchungsvorrichtung für biologische Proben und chemische Proben
CL2008002885A1 (es) Anticuerpo anti-receptor de interleucina-6 (il-6); y composicion farmaceutica que lo comprende
TW200616578A (en) Fluid handling devices
EP1955065A4 (de) Neue quantitative und qualitative analysevorrichtung zur messung der körperflüssigkeit
WO2006083305A3 (en) Methods and compositions for the detection of biological molecules using a two particle complex
NO20083397L (no) Anti-EphB4-antistoffer og fremgangsmater for anvendelse av disse
BRPI0812488A2 (pt) Anticorpos anti-cd44 humanizados e quiméricos que mediam citotoxidade de célula de câncer, usos dos mesmos, ensaios de ligação, métodos, composições e kit de ensaio
ATE428929T1 (de) Reagens, ausstattung und verfahren zur probenanalyse
WO2007114986A3 (en) Cooperative probes and methods of using them
PL1789793T3 (pl) Połączony test do wykrywania alkoholu i substancji odurzających
TW200745551A (en) Device and methods for detecting and quantifying one or more target agents
DE102005023067A8 (de) Vorrichtung zur Prüfung der Dichtungsbelastbarkeit
NO20060777L (no) Muskarine acetylkolinreseptorantagonister
DK1864131T3 (da) Naturlig ligand af G protein koblet receptor RCC356 og anvendelser deraf
EP1873522A4 (de) Verfahren zur bestimmung eines hämoglobinderivats sowie reagenszusammensetzung, testkit, analysevorrichtung und analysesystem zur verwendung in dem verfahren
DE112004002986A5 (de) Prüfanlage zur zerstörungsfreien Materialprüfung

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties