ATE437647T1 - Transporter mit beabstandeten arginin-teilchen - Google Patents

Transporter mit beabstandeten arginin-teilchen

Info

Publication number
ATE437647T1
ATE437647T1 AT02742477T AT02742477T ATE437647T1 AT E437647 T1 ATE437647 T1 AT E437647T1 AT 02742477 T AT02742477 T AT 02742477T AT 02742477 T AT02742477 T AT 02742477T AT E437647 T1 ATE437647 T1 AT E437647T1
Authority
AT
Austria
Prior art keywords
transport
transporter
moiety
arginine
subunit
Prior art date
Application number
AT02742477T
Other languages
English (en)
Inventor
Paul Wender
Jonathan Rothbard
Lee Wright
Erik Kreider
Christopher Vandeusen
Original Assignee
Cellgate Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellgate Inc filed Critical Cellgate Inc
Application granted granted Critical
Publication of ATE437647T1 publication Critical patent/ATE437647T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)
AT02742477T 2001-02-16 2002-02-14 Transporter mit beabstandeten arginin-teilchen ATE437647T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26962701P 2001-02-16 2001-02-16
PCT/US2002/004491 WO2002065986A2 (en) 2001-02-16 2002-02-14 Transporters comprising spaced arginine moieties

Publications (1)

Publication Number Publication Date
ATE437647T1 true ATE437647T1 (de) 2009-08-15

Family

ID=23028023

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02742477T ATE437647T1 (de) 2001-02-16 2002-02-14 Transporter mit beabstandeten arginin-teilchen

Country Status (9)

Country Link
US (3) US7585834B2 (de)
EP (1) EP1401473B1 (de)
JP (1) JP2005508832A (de)
AT (1) ATE437647T1 (de)
AU (1) AU2002306500C1 (de)
CA (1) CA2437983C (de)
DE (1) DE60233137D1 (de)
MX (1) MXPA03007358A (de)
WO (1) WO2002065986A2 (de)

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AU2002306500B2 (en) 2006-04-06
EP1401473B1 (de) 2009-07-29
CA2437983A1 (en) 2002-08-29
EP1401473A4 (de) 2004-07-28
MXPA03007358A (es) 2004-12-13
WO2002065986A2 (en) 2002-08-29
US20100081618A1 (en) 2010-04-01
US7585834B2 (en) 2009-09-08
WO2002065986A3 (en) 2004-01-22
US20120225826A1 (en) 2012-09-06
DE60233137D1 (de) 2009-09-10
EP1401473A2 (de) 2004-03-31
CA2437983C (en) 2011-10-25
US20030032593A1 (en) 2003-02-13
JP2005508832A (ja) 2005-04-07
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