ATE438099T1 - Bindungsassay unter verwendung eines magnetischen felds - Google Patents

Bindungsassay unter verwendung eines magnetischen felds

Info

Publication number
ATE438099T1
ATE438099T1 AT02767702T AT02767702T ATE438099T1 AT E438099 T1 ATE438099 T1 AT E438099T1 AT 02767702 T AT02767702 T AT 02767702T AT 02767702 T AT02767702 T AT 02767702T AT E438099 T1 ATE438099 T1 AT E438099T1
Authority
AT
Austria
Prior art keywords
magnetic field
binding assay
target molecule
immobilised
complexed
Prior art date
Application number
AT02767702T
Other languages
English (en)
Inventor
Richard Luxton
Peter Hawkins
Original Assignee
Randox Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Randox Lab Ltd filed Critical Randox Lab Ltd
Application granted granted Critical
Publication of ATE438099T1 publication Critical patent/ATE438099T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/005—Pretreatment specially adapted for magnetic separation
    • B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/28—Magnetic plugs and dipsticks
    • B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AT02767702T 2001-10-10 2002-10-10 Bindungsassay unter verwendung eines magnetischen felds ATE438099T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0124341.9A GB0124341D0 (en) 2001-10-10 2001-10-10 Assay
PCT/GB2002/004594 WO2003031977A2 (en) 2001-10-10 2002-10-10 Binding assay using a magnetic field

Publications (1)

Publication Number Publication Date
ATE438099T1 true ATE438099T1 (de) 2009-08-15

Family

ID=9923580

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02767702T ATE438099T1 (de) 2001-10-10 2002-10-10 Bindungsassay unter verwendung eines magnetischen felds

Country Status (9)

Country Link
US (1) US20050048672A1 (de)
EP (1) EP1434996B1 (de)
JP (1) JP4271034B2 (de)
CN (1) CN100343669C (de)
AT (1) ATE438099T1 (de)
DE (1) DE60233149D1 (de)
ES (1) ES2329556T3 (de)
GB (1) GB0124341D0 (de)
WO (1) WO2003031977A2 (de)

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US9494581B2 (en) * 2004-08-24 2016-11-15 University Of Wyoming System and method for Raman spectroscopy assay using paramagnetic particles
ES2393758T3 (es) * 2006-03-15 2012-12-27 Micronics, Inc. Ensayos integrados de ácidos nucleicos
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DE502007006595D1 (de) 2007-01-10 2011-04-14 Hoffmann La Roche Vorrichtung zum Bestimmen eines Analyts in einer Flüssigkeit und Verfahren
US9068977B2 (en) * 2007-03-09 2015-06-30 The Regents Of The University Of Michigan Non-linear rotation rates of remotely driven particles and uses thereof
WO2008114025A1 (en) 2007-03-21 2008-09-25 University Of The West Of England, Bristol Particle facilitated testing
EP2200727B1 (de) 2007-09-20 2014-08-13 Magarray, Inc. Nachweis von analyten mit magnetischen sensoren
EP2419733A4 (de) 2009-04-13 2013-12-25 Univ Leland Stanford Junior Verfahren und vorrichtungen zur erkennung des vorhandenseins eines analyts in einer probe
JP5791634B2 (ja) 2010-01-29 2015-10-07 マイクロニクス， インコーポレイテッド サンプル−回答型のマイクロ流体カートリッジ
JP5937019B2 (ja) 2010-03-12 2016-06-22 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 磁気センサに基づく結合反応速度の定量的な分析
WO2012027747A2 (en) 2010-08-27 2012-03-01 The Regents Of The University Of Michigan Asynchronous magnetic bead rotation sensing systems and methods
WO2012122536A2 (en) 2011-03-09 2012-09-13 Magarray, Inc. Systems and methods for high-throughput detection of an analyte in a sample
US9816993B2 (en) 2011-04-11 2017-11-14 The Regents Of The University Of Michigan Magnetically induced microspinning for super-detection and super-characterization of biomarkers and live cells
EP2537589A1 (de) * 2011-06-21 2012-12-26 Siemens Aktiengesellschaft Verfahren zum Trennen eines ersten Stoffes aus einem fließfähigen Primärstoffstrom, Vorrichtung zum Trennen eines ersten Stoffes aus einem fließfähigen Primärstoffstrom und Steuer- und/oder Regeleinrichtung
US10641768B2 (en) * 2011-07-08 2020-05-05 Abbott Japan Co. Ltd. Methods and kits for decreasing interferences from leukocytes in specific binding assays
US9797817B2 (en) 2012-05-03 2017-10-24 The Regents Of The University Of Michigan Multi-mode separation for target detection
KR20150096788A (ko) 2012-12-21 2015-08-25 마이크로닉스 인코포레이티드. 마이크로 유체공학 용도를 위한 저탄성 막
JP6498125B2 (ja) 2012-12-21 2019-04-10 マイクロニクス， インコーポレイテッド 流体回路および関連する製造方法
US10267871B2 (en) 2013-03-15 2019-04-23 Magarray, Inc. Magnetic tunnel junction sensors and methods for using the same
JP6472788B2 (ja) 2013-05-07 2019-02-20 マイクロニクス， インコーポレイテッド 粘土鉱物およびアルカリ性溶液を使用して核酸含有試料を調製するための方法
WO2014182847A1 (en) 2013-05-07 2014-11-13 Micronics, Inc. Device for preparation and analysis of nucleic acids
WO2014182844A1 (en) 2013-05-07 2014-11-13 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
US9983110B2 (en) 2013-11-04 2018-05-29 The Regents Of The University Of Michigan Asynchronous magnetic bead rotation (AMBR) microviscometer for analysis of analytes
CN106707050A (zh) * 2015-11-18 2017-05-24 国家电网公司 安全警戒带防滑专用定位器
CN109272100A (zh) * 2018-09-03 2019-01-25 南京冠盛汽配有限公司 轮毂轴承单元带端盖检测磁极数方法
CN114706023A (zh) * 2022-06-06 2022-07-05 中国科学技术大学 生物分子相互作用的磁学检测方法

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Also Published As

Publication number Publication date
JP4271034B2 (ja) 2009-06-03
DE60233149D1 (de) 2009-09-10
EP1434996A2 (de) 2004-07-07
ES2329556T3 (es) 2009-11-27
US20050048672A1 (en) 2005-03-03
WO2003031977A3 (en) 2003-09-25
EP1434996B1 (de) 2009-07-29
CN100343669C (zh) 2007-10-17
JP2005504989A (ja) 2005-02-17
CN1608205A (zh) 2005-04-20
WO2003031977A2 (en) 2003-04-17
GB0124341D0 (en) 2001-11-28

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