ATE438407T1 - Diagnose, vorbeugung und behandlung von ulcerativer colitis und deren subtypen unter verwendung mikrobieller uc panca antigene - Google Patents
Diagnose, vorbeugung und behandlung von ulcerativer colitis und deren subtypen unter verwendung mikrobieller uc panca antigeneInfo
- Publication number
- ATE438407T1 ATE438407T1 AT99911375T AT99911375T ATE438407T1 AT E438407 T1 ATE438407 T1 AT E438407T1 AT 99911375 T AT99911375 T AT 99911375T AT 99911375 T AT99911375 T AT 99911375T AT E438407 T1 ATE438407 T1 AT E438407T1
- Authority
- AT
- Austria
- Prior art keywords
- panca
- antigens
- microbial
- ulcerative colitis
- methods
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Gram-negative bacteria
- C07K16/1228—Enterobacterales (O), e.g. Citrobacter (G), Serratia (G), Proteus (G), Providencia (G), Morganella (G) or Yersinia (G)
- C07K16/1232—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/06—Gastro-intestinal diseases
- G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Epidemiology (AREA)
- Marine Sciences & Fisheries (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/041,889 US6033864A (en) | 1996-04-12 | 1998-03-12 | Diagnosis, prevention and treatment of ulcerative colitis, and clinical subtypes thereof, using microbial UC pANCA antigens |
| PCT/US1999/005492 WO1999045955A1 (en) | 1998-03-12 | 1999-03-12 | DIAGNOSIS, PREVENTION AND TREATMENT OF ULCERATIVE COLITIS, AND CLINICAL SUBTYPES THEREOF, USING MICROBIAL UC pANCA ANTIGENS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE438407T1 true ATE438407T1 (de) | 2009-08-15 |
Family
ID=21918893
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99911375T ATE438407T1 (de) | 1998-03-12 | 1999-03-12 | Diagnose, vorbeugung und behandlung von ulcerativer colitis und deren subtypen unter verwendung mikrobieller uc panca antigene |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US6033864A (de) |
| EP (1) | EP1069907B1 (de) |
| AT (1) | ATE438407T1 (de) |
| AU (1) | AU3002699A (de) |
| CA (1) | CA2322763C (de) |
| DE (1) | DE69941214D1 (de) |
| WO (1) | WO1999045955A1 (de) |
Families Citing this family (91)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9924351D0 (en) | 1999-10-14 | 1999-12-15 | Brennan Frank | Immunomodulation methods and compositions |
| US6348316B1 (en) * | 2000-04-12 | 2002-02-19 | Cedars-Sinai Medical Center | Genetic testing for determining the risk of pouchitis development |
| US7138237B1 (en) * | 2000-05-19 | 2006-11-21 | Cedars-Sinai Medical Center | Diagnosis, prevention and treatment of Crohn's disease using the OmpC antigen |
| US6821739B2 (en) * | 2000-10-13 | 2004-11-23 | The Regents Of The University Of California | Methods of diagnosing and treating Crohn's disease using Pseudomonas antigens |
| GB0127916D0 (en) | 2001-11-21 | 2002-01-16 | Rowett Res Inst | Method |
| US20040029786A1 (en) * | 2002-05-08 | 2004-02-12 | Das Kiron M | Treatment of ulcerative colitis by introducing CEP antigen composition |
| US20080193945A1 (en) * | 2002-06-25 | 2008-08-14 | Index Diagnostics Ab | Method and Kit for the Diagnosis of Ulcerative Colitis |
| ATE538128T1 (de) * | 2002-09-05 | 2012-01-15 | Techlab Inc | Verfahren zur unterscheidung von colitis ulcerosa von morbus crohn durch nachweis des vorliegens von fäkalen anti-neutrophilen cytoplasmatischen antikörpern (anca) |
| ES2306902T3 (es) * | 2002-10-25 | 2008-11-16 | Techlab, Inc. | Panel de diagnostico ibd-first chek para la enfermedad inflamatoria del intestino y el sindrome del colon irritable. |
| WO2004055214A1 (en) * | 2002-12-18 | 2004-07-01 | Department Of Biotechnology | The characterization of hupb gene encoding histone like protein of mycobacterium tuberculosis |
| US20050058663A1 (en) * | 2003-09-17 | 2005-03-17 | Monif Gilles R. G. | Mycobacterium avium subspecies paratuberculosis oral vaccine and methods |
| US20060205022A1 (en) * | 2003-12-03 | 2006-09-14 | Nir Dotan | Method for diagnosing and prognosing inflammatory bowel disease and crohn's disease |
| EP1692519B1 (de) * | 2003-12-03 | 2010-06-02 | Glycominds Ltd. | Diagnostikverfahren mittels messungen der antiglykan-antikörper-spiegeln |
| US7592150B2 (en) * | 2003-12-03 | 2009-09-22 | Glycominds, Ltd | Method for diagnosing diseases based on levels of anti-glycan antibodies |
| US7759079B2 (en) * | 2004-05-13 | 2010-07-20 | Prometheus Laboratories Inc. | Methods of diagnosing inflammatory bowel disease |
| US20060154276A1 (en) | 2004-05-13 | 2006-07-13 | Prometheus Laboratories Inc. | Methods of diagnosing inflammatory bowel disease |
| US7964554B2 (en) | 2004-09-03 | 2011-06-21 | Amateraspharma Inc. | Polypeptide that binds anti-histone H1 antibody |
| US20090197249A1 (en) * | 2004-11-01 | 2009-08-06 | George Mason University | Compositions and methods for diagnosing colon disorders |
| US7873479B2 (en) | 2005-12-01 | 2011-01-18 | Prometheus Laboratories Inc. | Methods of diagnosing inflammatory bowel disease |
| US8685741B1 (en) | 2007-03-07 | 2014-04-01 | Nestec S.A. | Methods for diagnosing irritable bowel syndrome |
| CN101784655A (zh) * | 2007-04-27 | 2010-07-21 | 菲尼克斯股份有限公司 | 可溶性重组二十面体病毒样颗粒的改良生成和体内装配 |
| US20110136255A1 (en) * | 2007-11-30 | 2011-06-09 | Nir Dotan | Composition and method for prediction of complicated disease course in crohn's disease |
| DK2223121T3 (da) | 2007-12-20 | 2012-10-22 | Index Diagnostics Ab Publ | Fremgangsmåde og kit til anvendelse ved differentiering mellem ibd og ibs og yderligere skelnen mellem ibd-sygdomstyper |
| WO2010056682A2 (en) | 2008-11-11 | 2010-05-20 | Prometheus Laboratories Inc. | Methods for prediction of inflammatory bowel disease (ibd) using serologic markers |
| WO2010120814A1 (en) | 2009-04-14 | 2010-10-21 | Prometheus Laboratories Inc. | Inflammatory bowel disease prognostics |
| EP3309556B1 (de) | 2009-06-25 | 2020-04-08 | Prometheus Biosciences, Inc. | Verfahren zur diagnostizierung des reizdarmsyndroms |
| WO2011060098A1 (en) | 2009-11-10 | 2011-05-19 | Prometheus Laboratories Inc. | Methods for predicting post-surgery risk associated with ileal pouch-anal anastomosis |
| US8445215B1 (en) | 2010-07-23 | 2013-05-21 | Nestec S.A. | Assays and methods for the detection of Crohn's disease |
| US9511151B2 (en) | 2010-11-12 | 2016-12-06 | Uti Limited Partnership | Compositions and methods for the prevention and treatment of cancer |
| CA2827609A1 (en) | 2011-02-17 | 2012-11-15 | Nestec S.A. | Assays for detecting autoantibodies to anti-tnf.alpha. drugs |
| AU2012253422B2 (en) | 2011-05-10 | 2015-08-13 | Société des Produits Nestlé S.A. | Methods of disease activity profiling for personalized therapy management |
| WO2012158831A1 (en) | 2011-05-16 | 2012-11-22 | Prometheus Laboratories Inc. | Performance of a biomarker panel for irritable bowel syndrome |
| GB201112091D0 (en) | 2011-07-14 | 2011-08-31 | Gt Biolog Ltd | Bacterial strains isolated from pigs |
| GB201117313D0 (en) | 2011-10-07 | 2011-11-16 | Gt Biolog Ltd | Bacterium for use in medicine |
| JP2015502740A (ja) | 2011-10-21 | 2015-01-29 | ネステク ソシエテ アノニム | 炎症性腸疾患の診断を改善するための方法 |
| US10988516B2 (en) * | 2012-03-26 | 2021-04-27 | Uti Limited Partnership | Methods and compositions for treating inflammation |
| US9603948B2 (en) | 2012-10-11 | 2017-03-28 | Uti Limited Partnership | Methods and compositions for treating multiple sclerosis and related disorders |
| US9128098B2 (en) | 2012-10-31 | 2015-09-08 | Gilles R. G. Monif | Fuidi herd management and risk stratification methods |
| GB201306536D0 (en) | 2013-04-10 | 2013-05-22 | Gt Biolog Ltd | Polypeptide and immune modulation |
| AU2014343379B2 (en) | 2013-11-04 | 2019-02-14 | Uti Limited Partnership | Methods and compositions for sustained immunotherapy |
| WO2015083087A1 (en) | 2013-12-03 | 2015-06-11 | Nestec S.A. | Methods for predicting post-operative recurrence of crohn's disease |
| US9758839B2 (en) | 2014-10-21 | 2017-09-12 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome functional features |
| US10265009B2 (en) | 2014-10-21 | 2019-04-23 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome taxonomic features |
| US10409955B2 (en) | 2014-10-21 | 2019-09-10 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for locomotor system conditions |
| US9754080B2 (en) | 2014-10-21 | 2017-09-05 | uBiome, Inc. | Method and system for microbiome-derived characterization, diagnostics and therapeutics for cardiovascular disease conditions |
| US10388407B2 (en) | 2014-10-21 | 2019-08-20 | uBiome, Inc. | Method and system for characterizing a headache-related condition |
| US10410749B2 (en) | 2014-10-21 | 2019-09-10 | uBiome, Inc. | Method and system for microbiome-derived characterization, diagnostics and therapeutics for cutaneous conditions |
| WO2016065075A1 (en) | 2014-10-21 | 2016-04-28 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics |
| US10073952B2 (en) | 2014-10-21 | 2018-09-11 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for autoimmune system conditions |
| US10793907B2 (en) | 2014-10-21 | 2020-10-06 | Psomagen, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for endocrine system conditions |
| US10357157B2 (en) | 2014-10-21 | 2019-07-23 | uBiome, Inc. | Method and system for microbiome-derived characterization, diagnostics and therapeutics for conditions associated with functional features |
| US10169541B2 (en) | 2014-10-21 | 2019-01-01 | uBiome, Inc. | Method and systems for characterizing skin related conditions |
| US10311973B2 (en) | 2014-10-21 | 2019-06-04 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for autoimmune system conditions |
| US9710606B2 (en) | 2014-10-21 | 2017-07-18 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for neurological health issues |
| US10346592B2 (en) | 2014-10-21 | 2019-07-09 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for neurological health issues |
| US10366793B2 (en) | 2014-10-21 | 2019-07-30 | uBiome, Inc. | Method and system for characterizing microorganism-related conditions |
| US10395777B2 (en) | 2014-10-21 | 2019-08-27 | uBiome, Inc. | Method and system for characterizing microorganism-associated sleep-related conditions |
| US11783914B2 (en) | 2014-10-21 | 2023-10-10 | Psomagen, Inc. | Method and system for panel characterizations |
| US10381112B2 (en) | 2014-10-21 | 2019-08-13 | uBiome, Inc. | Method and system for characterizing allergy-related conditions associated with microorganisms |
| US10777320B2 (en) | 2014-10-21 | 2020-09-15 | Psomagen, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for mental health associated conditions |
| US10789334B2 (en) | 2014-10-21 | 2020-09-29 | Psomagen, Inc. | Method and system for microbial pharmacogenomics |
| US9760676B2 (en) | 2014-10-21 | 2017-09-12 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for endocrine system conditions |
| US10325685B2 (en) | 2014-10-21 | 2019-06-18 | uBiome, Inc. | Method and system for characterizing diet-related conditions |
| AR103260A1 (es) | 2014-12-23 | 2017-04-26 | 4D Pharma Res Ltd | Modulación inmunitaria |
| EP3400953A1 (de) | 2014-12-23 | 2018-11-14 | 4D Pharma Research Limited | Pirinpolypeptid und immunmodulation |
| US10246753B2 (en) | 2015-04-13 | 2019-04-02 | uBiome, Inc. | Method and system for characterizing mouth-associated conditions |
| EP3291832B1 (de) | 2015-05-06 | 2025-09-03 | UTI Limited Partnership | Nanopartikelzusammensetzungen zur verzögerten therapie |
| WO2016203221A1 (en) | 2015-06-15 | 2016-12-22 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| MA41060B1 (fr) | 2015-06-15 | 2019-11-29 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| SMT201900588T1 (it) | 2015-06-15 | 2019-11-13 | 4D Pharma Res Limited | Blautia stercoris e wexlerae per uso nel trattamento di malattie infiammatorie ed autoimmuni |
| MA41010B1 (fr) | 2015-06-15 | 2020-01-31 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| NZ737752A (en) | 2015-06-15 | 2022-02-25 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| WO2017079653A2 (en) | 2015-11-06 | 2017-05-11 | Vetica Labs, Inc. | Methods of detecting inflammatory markers and treating inflammatory conditions in companion animals |
| GB201520497D0 (en) | 2015-11-20 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| CN108513545B (zh) | 2015-11-20 | 2020-11-03 | 4D制药研究有限公司 | 包含细菌菌株的组合物 |
| GB201520631D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| GB201520638D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| GB201612191D0 (en) | 2016-07-13 | 2016-08-24 | 4D Pharma Plc | Compositions comprising bacterial strains |
| ME03487B (de) | 2016-03-04 | 2020-01-20 | 4D Pharma Plc | Zusammensetzungen mit bakteriellen blautia-stämmen zur behandlung von viszeraler überempfindlichkeit |
| TWI802545B (zh) | 2016-07-13 | 2023-05-21 | 英商4D製藥有限公司 | 包含細菌菌株之組合物 |
| GB201621123D0 (en) | 2016-12-12 | 2017-01-25 | 4D Pharma Plc | Compositions comprising bacterial strains |
| DK3630136T3 (da) | 2017-05-22 | 2021-05-25 | 4D Pharma Res Ltd | Sammensætninger, der omfatter bakteriestammer |
| EP3630942B1 (de) | 2017-05-24 | 2022-11-30 | 4D Pharma Research Limited | Zusammensetzungen mit bakterienstamm |
| CA3066189A1 (en) | 2017-06-14 | 2018-12-20 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| SMT202000555T1 (it) | 2017-06-14 | 2020-11-10 | 4D Pharma Res Limited | Composizioni comprendenti un ceppo batterico del genere megaspaera e loro usi |
| SMT202000695T1 (it) | 2017-06-14 | 2021-01-05 | 4D Pharma Res Limited | Composizioni comprendenti ceppi batterici |
| CA3083748A1 (en) | 2017-11-29 | 2019-06-06 | Uti Limited Partnership | Methods of treating autoimmune disease |
| WO2019186084A1 (en) * | 2018-03-26 | 2019-10-03 | The University Of Liverpool | Anti-complement histones |
| BR112020017257A2 (pt) * | 2018-03-29 | 2020-12-22 | Kimberly-Clark Worldwide, Inc. | Sensor, artigo absorvente, e, método para indicar um potencial problema de pele ou gastrointestinal. |
| CN111187344A (zh) * | 2019-12-19 | 2020-05-22 | 北京安锐鑫生物科技有限公司 | 多肽、包含其的组合物、及其预防或治疗皮肤损伤或抗氧化药物的应用 |
| US12391912B2 (en) | 2021-10-26 | 2025-08-19 | Rensselaer Polytechnic Institute | Systems and methods for increased production of recombinant biopolymers via genome engineering and downregulation of basal expression |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1985003003A1 (fr) * | 1984-01-12 | 1985-07-18 | Volker Rusch | Substance biologiquement active avec des proprietes hormonales, son procede de fabrication et utilisation d'histones a des fins medicales |
| US5830675A (en) * | 1993-03-10 | 1998-11-03 | Cedars-Sinai Medical Center | Methods for selectively detecting perinuclear anti-neutrophil cytoplasmic antibody of ulcerative colitis, primary sclerosing cholangitis, or type 1 autoimmune hepatitis |
| IL126535A (en) * | 1996-04-12 | 2002-11-10 | Cedars Sinai Medical Center | Diagnosis of ulcerative colitis and subtypes of the above using histone H1 |
| US6074835A (en) * | 1996-04-12 | 2000-06-13 | Regents Of The Univ. Of California | Diagnosis, prevention and treatment of ulcerative colitis, and clinical subtypes thereof, using histone H1 |
-
1998
- 1998-03-12 US US09/041,889 patent/US6033864A/en not_active Expired - Lifetime
-
1999
- 1999-03-12 AU AU30026/99A patent/AU3002699A/en not_active Abandoned
- 1999-03-12 EP EP99911375A patent/EP1069907B1/de not_active Expired - Lifetime
- 1999-03-12 CA CA2322763A patent/CA2322763C/en not_active Expired - Lifetime
- 1999-03-12 DE DE69941214T patent/DE69941214D1/de not_active Expired - Lifetime
- 1999-03-12 AT AT99911375T patent/ATE438407T1/de not_active IP Right Cessation
- 1999-03-12 WO PCT/US1999/005492 patent/WO1999045955A1/en not_active Ceased
- 1999-10-12 US US09/417,264 patent/US6537768B1/en not_active Expired - Lifetime
-
2002
- 2002-08-27 US US10/229,567 patent/US7183065B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2322763A1 (en) | 1999-09-16 |
| US20030092080A1 (en) | 2003-05-15 |
| AU3002699A (en) | 1999-09-27 |
| EP1069907B1 (de) | 2009-08-05 |
| DE69941214D1 (de) | 2009-09-17 |
| US6537768B1 (en) | 2003-03-25 |
| WO1999045955A1 (en) | 1999-09-16 |
| EP1069907A4 (de) | 2003-03-05 |
| HK1035662A1 (en) | 2001-12-07 |
| WO1999045955A9 (en) | 2000-02-17 |
| US6033864A (en) | 2000-03-07 |
| EP1069907A1 (de) | 2001-01-24 |
| US7183065B2 (en) | 2007-02-27 |
| CA2322763C (en) | 2012-05-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69941214D1 (de) | DIAGNOSE, VORBEUGUNG UND BEHANDLUNG VON ULCERATIVER COLITIS UND DEREN SUBTYPEN UNTER VERWENDUNG MIKROBIELLER UC pANCA ANTIGENE | |
| ATE192339T1 (de) | Verwendung von fulleren-derivaten in diagnostischen und/oder therapeutischen mitteln | |
| FR12C0004I2 (fr) | Anticorps contre l'antigene ctla-4 humain et utilisation | |
| ATE418565T1 (de) | Antikörper gegen nichtfunktionelle p 2 x 7 rezeptoren, diagnose und behandlung von krebs und anderen leiden | |
| TR199801255T2 (xx) | Vitronektin resept�r antagonistleri. | |
| NO973447L (no) | Monoklonale antistoffer som er spesifikke for forskjellige epitoper i human-gp 39, og fremgangsmåter for deres anvendelse i diagnose og terapi | |
| CY1111863T1 (el) | Αντισωματα εναντιον υποδοχεα θανατου 4 (dr4) και χρησεις αυτων | |
| DE69322860D1 (de) | Antikörper gegen alpha v beta 3 integrin | |
| ATE462710T1 (de) | Mutationen in nod2 sind bei patienten mit morbus crohn mit fibrostenosebildung assoziiert | |
| DE69526973D1 (de) | Sequenzen von hepatitis-c-virus genotype 7, und deren verwendung als vorbeugende, therapeutische und diagnostische mittel | |
| RU94045826A (ru) | Моноклональные антитела против рецептора интерферона, с нейтрализующим действием против интерферона типа i | |
| TR200102963T2 (tr) | Yeni tedavi metodu | |
| NO331101B1 (no) | In vitro-fremgangsmate for a uttrykke et antigenmolekyl og antigenmolekyl og et fotosensibiliserende middel for anvendelse ved uttrykking av antigenmolekylet. | |
| RU94046284A (ru) | Способ обнаружения антител, способ с-крекинга компонентов крови, набор для обнаружения антител к hcv | |
| TR199900656T2 (xx) | �ndanonlar ile 262 ve 20S proteazomun engellenmesi. | |
| KR910005862A (ko) | 신규 친수성 유도체, 진단 또는 치료시 그의 응용 그를 함유하는 진단 또는 치료용 키트 및 면역 시약 | |
| BR0113213A (pt) | Método para diagnosticar uma doença auto-imune, anticorpo, composição de diagnóstico, e, uso do anticorpo | |
| DK0584715T3 (da) | Fremgangsmåde til isolering og dyrkning af transformerede celler og anvendelse af disse til fremstilling af antistoffer ret | |
| EP0674661A4 (de) | Test und behandlung von demyelinierenden krankheiten wie multiple sklerosis. | |
| FR2491334B1 (de) | ||
| ATE442439T1 (de) | Melanoma antigene p15 und deren anwendung in diagnostischen und therapeutischen verfahren | |
| ES2032447T3 (es) | Nuevos anticuerpos monoclonales y su produccion y uso. | |
| SE8701905D0 (sv) | A method and a kit for the diagnosis of iga nephropathy | |
| EA200100264A1 (ru) | Ангиоцидин: адгезионный рецептор опухолей клетки, специфический для cys-ser-val-thr-cys-gly | |
| DE69426767D1 (de) | Anti idiotypische Antikörper gegen Gonococcen und diese verwendende Verfahren und Zusammensetzungen. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |