ATE439141T1 - Zusammensetzungen basierend auf midkine zur behandlung von chronischen ischämienreperfusionsschäden - Google Patents
Zusammensetzungen basierend auf midkine zur behandlung von chronischen ischämienreperfusionsschädenInfo
- Publication number
- ATE439141T1 ATE439141T1 AT05814479T AT05814479T ATE439141T1 AT E439141 T1 ATE439141 T1 AT E439141T1 AT 05814479 T AT05814479 T AT 05814479T AT 05814479 T AT05814479 T AT 05814479T AT E439141 T1 ATE439141 T1 AT E439141T1
- Authority
- AT
- Austria
- Prior art keywords
- midkine
- treatment
- reperfusion injury
- compositions based
- chronic ischemia
- Prior art date
Links
- 102000016776 Midkine Human genes 0.000 title abstract 5
- 108010092801 Midkine Proteins 0.000 title abstract 5
- 206010063837 Reperfusion injury Diseases 0.000 title 1
- 230000001684 chronic effect Effects 0.000 title 1
- 208000012947 ischemia reperfusion injury Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 241000699670 Mus sp. Species 0.000 abstract 2
- 210000004413 cardiac myocyte Anatomy 0.000 abstract 2
- 230000006907 apoptotic process Effects 0.000 abstract 1
- 230000002950 deficient Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 208000028867 ischemia Diseases 0.000 abstract 1
- 238000010172 mouse model Methods 0.000 abstract 1
- 230000003680 myocardial damage Effects 0.000 abstract 1
- 230000010410 reperfusion Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004352513 | 2004-12-06 | ||
| JP2005187420A JP4791770B2 (ja) | 2004-12-06 | 2005-06-27 | 心筋障害又は心不全の治療もしくは予防組成物 |
| PCT/JP2005/022354 WO2006062087A1 (ja) | 2004-12-06 | 2005-12-06 | 心筋障害又は心不全の治療もしくは予防組成物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE439141T1 true ATE439141T1 (de) | 2009-08-15 |
Family
ID=36577914
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05814479T ATE439141T1 (de) | 2004-12-06 | 2005-12-06 | Zusammensetzungen basierend auf midkine zur behandlung von chronischen ischämienreperfusionsschäden |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9023799B2 (de) |
| EP (1) | EP1832296B1 (de) |
| JP (1) | JP4791770B2 (de) |
| AT (1) | ATE439141T1 (de) |
| DE (1) | DE602005016016D1 (de) |
| WO (1) | WO2006062087A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5025646B2 (ja) * | 2005-11-08 | 2012-09-12 | 公益財団法人先端医療振興財団 | 虚血性心疾患の治療方法 |
| JPWO2008129851A1 (ja) * | 2007-03-30 | 2010-07-22 | 国立大学法人名古屋大学 | 一酸化窒素合成酵素活性化剤 |
| WO2017081224A1 (en) * | 2015-11-12 | 2017-05-18 | Celltrend Gmbh | Prognosis of adverse outcomes by determination of midkine levels after cardiovascular stress |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0827021A (ja) * | 1994-07-22 | 1996-01-30 | Mitsui Toatsu Chem Inc | 医薬組成物 |
| WO1998001151A1 (en) * | 1996-07-10 | 1998-01-15 | Meiji Milk Products Co., Ltd. | Novel use of mk family as hematopoietic factor |
| KR100554294B1 (ko) | 1997-09-26 | 2006-02-24 | 무라마쯔 다카시 | 허혈성 질환의 예방 또는 치료제 |
| US8106009B2 (en) * | 1997-09-26 | 2012-01-31 | Medical Therapies Limited | Pharmaceutical composition for preventing or treating ischemic diseases |
| CA2329010A1 (en) | 1998-04-17 | 1999-10-28 | Angiogenix Incorporated | Therapeutic angiogenic factors and methods for their use |
| US20050079151A1 (en) * | 1998-07-10 | 2005-04-14 | Shinya Ikematsu | Therapeutic agents for apoptosis-related diseases |
| KR20010071798A (ko) * | 1998-07-10 | 2001-07-31 | 무라마쯔 다카시 | 세포자멸사 관련질환 치료제 |
| JP2005068122A (ja) * | 2003-08-27 | 2005-03-17 | Mitsuru Horiba | ミッドカインによる心筋障害予防および治療への応用。 |
| US20060216709A1 (en) * | 2003-12-10 | 2006-09-28 | Carmit Levita | Midkine-like protein |
| JP5025646B2 (ja) * | 2005-11-08 | 2012-09-12 | 公益財団法人先端医療振興財団 | 虚血性心疾患の治療方法 |
-
2005
- 2005-06-27 JP JP2005187420A patent/JP4791770B2/ja not_active Expired - Fee Related
- 2005-12-06 DE DE602005016016T patent/DE602005016016D1/de not_active Expired - Lifetime
- 2005-12-06 AT AT05814479T patent/ATE439141T1/de not_active IP Right Cessation
- 2005-12-06 US US11/720,983 patent/US9023799B2/en active Active
- 2005-12-06 WO PCT/JP2005/022354 patent/WO2006062087A1/ja not_active Ceased
- 2005-12-06 EP EP05814479A patent/EP1832296B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US9023799B2 (en) | 2015-05-05 |
| WO2006062087A1 (ja) | 2006-06-15 |
| JP2006188483A (ja) | 2006-07-20 |
| US20100056437A1 (en) | 2010-03-04 |
| EP1832296A1 (de) | 2007-09-12 |
| EP1832296B1 (de) | 2009-08-12 |
| DE602005016016D1 (de) | 2009-09-24 |
| EP1832296A4 (de) | 2008-01-16 |
| JP4791770B2 (ja) | 2011-10-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |