ATE439338T1 - Mehrfach ungesättigte, geradkettige aldehyde und deren derivate mit anti-radikalwirkung - Google Patents
Mehrfach ungesättigte, geradkettige aldehyde und deren derivate mit anti-radikalwirkungInfo
- Publication number
- ATE439338T1 ATE439338T1 AT03749867T AT03749867T ATE439338T1 AT E439338 T1 ATE439338 T1 AT E439338T1 AT 03749867 T AT03749867 T AT 03749867T AT 03749867 T AT03749867 T AT 03749867T AT E439338 T1 ATE439338 T1 AT E439338T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- straight chain
- chain aldehydes
- poly unsaturated
- radical effect
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/11—Aldehydes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
- A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4986—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/738—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/02—Acyclic alcohols with carbon-to-carbon double bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/21—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
- C07C69/22—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety
- C07C69/24—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with monohydroxylic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Nanotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medical Informatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2002MI000960A ITMI20020960A1 (it) | 2002-05-07 | 2002-05-07 | Aldeidi lineari poliinsature e loro derivati ad attivita' antiradicalica e antitumorale |
| PCT/EP2003/004720 WO2003095403A1 (en) | 2002-05-07 | 2003-05-06 | Polyunsaturated linear aldehydes and their derivatives with anti-radical and anti-tumoral activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE439338T1 true ATE439338T1 (de) | 2009-08-15 |
Family
ID=11449841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03749867T ATE439338T1 (de) | 2002-05-07 | 2003-05-06 | Mehrfach ungesättigte, geradkettige aldehyde und deren derivate mit anti-radikalwirkung |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20050175555A1 (de) |
| EP (1) | EP1501774B9 (de) |
| AT (1) | ATE439338T1 (de) |
| AU (1) | AU2003232722A1 (de) |
| CY (1) | CY1109512T1 (de) |
| DE (1) | DE60328769D1 (de) |
| DK (1) | DK1501774T3 (de) |
| ES (1) | ES2329890T3 (de) |
| IT (1) | ITMI20020960A1 (de) |
| PT (1) | PT1501774E (de) |
| SI (1) | SI1501774T1 (de) |
| WO (1) | WO2003095403A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0111872D0 (en) * | 2001-05-15 | 2001-07-04 | Northwick Park Inst For Medica | Therapeutic agents and methods |
| EP2042181A1 (de) * | 2002-02-04 | 2009-04-01 | ALFAMA-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda. | Verwendung CO- freisetzender Substanzen zur Herstellung eines Medikaments für die Behandlung entzündlicher Erkrankungen |
| US7968605B2 (en) * | 2002-02-04 | 2011-06-28 | ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. | Methods for treating inflammatory disease by administering aldehydes and derivatives thereof |
| US20080026984A1 (en) * | 2002-02-04 | 2008-01-31 | Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda | Methods for treating inflammatory disease by administering aldehydes and derivatives thereof |
| GB2395432B (en) * | 2002-11-20 | 2005-09-14 | Northwick Park Inst For Medica | Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs |
| WO2007073226A1 (en) * | 2005-12-20 | 2007-06-28 | Alfama - Investigação E Desenvolvimento De Produtos Farmacêuticos Lda | Method for treating a mammal by administration of a compound having the ability to release co |
| GB0601394D0 (en) | 2006-01-24 | 2006-03-01 | Hemocorm Ltd | Therapeutic delivery of carbon monoxide |
| GB0605900D0 (en) * | 2006-03-23 | 2006-05-03 | Lipigen As | Modulators of nuclear receptors |
| US9078852B2 (en) * | 2008-02-29 | 2015-07-14 | The Brigham And Women's Hospital, Inc. | Retinaldehyde in the treatment of obesity, diabetes and other conditions |
| IT1394921B1 (it) * | 2008-11-10 | 2012-07-27 | Giuliani Spa | Uso di composti come principi attivi per migliorare l'azione di riparazione cellulare dell'epidermide umana, e composizioni farmaceutiche e cosmetiche che li contengono |
| IT1391663B1 (it) * | 2008-11-10 | 2012-01-17 | Giuliani Spa | Uso di composti atti ad inibire l' attivita' dell'enzima 5alfa-reduttasi e composizioni farmaceutiche e cosmetiche che li contengono |
| EP2241543A1 (de) * | 2009-04-17 | 2010-10-20 | Giuliani S.p.A. | Verfahren zur Herstellung von 2,4,6-Octatrien-1-säure und 2,4,6-Octatrien-1-ol |
| IT1401289B1 (it) * | 2010-04-22 | 2013-07-18 | Giuliani Spa | Composti dotati di attivita' antiossidante nei confronti dei radicali liberi, e composizioni farmaceutiche e cosmetiche che li contengono |
| EP2407163A1 (de) | 2010-07-16 | 2012-01-18 | Giuliani S.p.A. | Verbindungen mit einer Hautpigmentierungsaktivität und pharmazeutische oder kosmetische Zusammensetzungen damit |
| US9163044B2 (en) | 2011-04-19 | 2015-10-20 | Alfama, Inc. | Carbon monoxide releasing molecules and uses thereof |
| WO2013013179A1 (en) | 2011-07-21 | 2013-01-24 | Alfama, Inc. | Ruthenium carbon monoxide releasing molecules and uses thereof |
| JP2023142625A (ja) * | 2022-03-25 | 2023-10-05 | 株式会社ダイセル | クロトンアルデヒドの製造方法 |
| CN117229132B (zh) * | 2023-11-10 | 2024-02-20 | 济南悟通生物科技有限公司 | 一种反式-2,4-壬二烯醛的合成方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3679792A (en) * | 1969-09-05 | 1972-07-25 | Wrigley W M Jun Co | Dialdehyde-containing anti-caries chewing gum compositions |
| DE10200130A1 (de) * | 2002-01-04 | 2003-07-10 | Basf Ag | Verfahren zur Herstellung von Polyendialdehydmonoacetalen |
-
2002
- 2002-05-07 IT IT2002MI000960A patent/ITMI20020960A1/it unknown
-
2003
- 2003-05-06 ES ES03749867T patent/ES2329890T3/es not_active Expired - Lifetime
- 2003-05-06 AU AU2003232722A patent/AU2003232722A1/en not_active Abandoned
- 2003-05-06 AT AT03749867T patent/ATE439338T1/de active
- 2003-05-06 SI SI200331667T patent/SI1501774T1/sl unknown
- 2003-05-06 WO PCT/EP2003/004720 patent/WO2003095403A1/en not_active Ceased
- 2003-05-06 PT PT03749867T patent/PT1501774E/pt unknown
- 2003-05-06 DE DE60328769T patent/DE60328769D1/de not_active Expired - Lifetime
- 2003-05-06 EP EP03749867A patent/EP1501774B9/de not_active Expired - Lifetime
- 2003-05-06 US US10/513,450 patent/US20050175555A1/en not_active Abandoned
- 2003-05-06 DK DK03749867T patent/DK1501774T3/da active
-
2009
- 2009-10-21 CY CY20091101096T patent/CY1109512T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK1501774T3 (da) | 2009-12-14 |
| EP1501774B1 (de) | 2009-08-12 |
| EP1501774B9 (de) | 2010-02-24 |
| WO2003095403A1 (en) | 2003-11-20 |
| ES2329890T3 (es) | 2009-12-02 |
| SI1501774T1 (sl) | 2009-12-31 |
| US20050175555A1 (en) | 2005-08-11 |
| ITMI20020960A1 (it) | 2003-11-07 |
| DE60328769D1 (de) | 2009-09-24 |
| ITMI20020960A0 (it) | 2002-05-07 |
| CY1109512T1 (el) | 2014-08-13 |
| EP1501774A1 (de) | 2005-02-02 |
| PT1501774E (pt) | 2009-10-15 |
| AU2003232722A1 (en) | 2003-11-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60328769D1 (de) | Mehrfach ungesättigte, geradkettige aldehyde und deren derivate mit anti-radikalwirkung | |
| EP2468273A3 (de) | Verfahren zur Reduzierung von oxidativer Schädigung und zur Verbesserung der mitochondrialen Effizienz | |
| EP3330252A3 (de) | Isoprenylverbindungen und verfahren dafür | |
| WO2009132174A3 (en) | Methods and compositions for improving the nutritional content of mushrooms and fungi | |
| ATE442426T1 (de) | Antioxidative makromonomere, deren herstellung und verwendung | |
| CY1113166T1 (el) | Αναστολεις των ενζυμων ενεργοποιησης ε1 | |
| CY1113114T1 (el) | Αναστολεις των ενζυμων ενεργοποιησης ε1 | |
| CR10458A (es) | Compuestos de triazolopirazina utiles para el tratamiento de enfermedades degenerativas e inflamatorias | |
| CY1121244T1 (el) | Συνδυασμος αναστολεα τελομερασης και γεμσιταβινής για τη θεραπεια του καρκινου | |
| CR11871A (es) | 1,2,5-oxadiazoles como inhibidores de indolamina 2,3- dioxigenasa | |
| EA200901289A1 (ru) | Композиции и способы для противовосполительного лечения | |
| CL2020000695A1 (es) | Composición que comprende aceite vegetal y vinagre de sidra de manzana. | |
| DK1841756T3 (da) | 3-heterocyclyl-3-hydroxy-2-amino-propionisyre-amider og relaterede forbindelser med analgesisk og/eller immunostimulatorisk aktivitet | |
| WO2010065850A3 (en) | Interleukin 6 and tumor necrosis factor alpha as biomarkers of jnk inhibition | |
| WO2009070244A3 (en) | Methods for inhibiting fascin | |
| MX338807B (es) | Composicion farmaceutica que comprende un compuesto indol. | |
| CL2012000392A1 (es) | Uso de un anticuerpo anti-cd20 afucosilado con una cantidad de fucosa de 60% o menos para tratar cancer en combinacion con fludarabina . | |
| KR102560772B9 (ko) | 신규한 이온화지질 및 이를 이용한 지질나노입자 조성물 | |
| RU2015112839A (ru) | Составы, содержащие идебенон, n-ацетил-s-фарнезил-l-цистеин и эрготионеин, и их применение | |
| TW200641038A (en) | Polylactic acid cross-linked material and method for making the same | |
| WO2007041418A3 (en) | Methods and compositions for improving cognitive function | |
| MX2009009533A (es) | Conjugados de hidroxipolimero modificado con efecto letal en celulas tumorales. | |
| DE50307423D1 (de) | Kationische polymerisate und deren verwendung in kosmetischen formulierungen | |
| WO2009017161A1 (ja) | 炎症性サイトカインの抑制剤 | |
| MY172984A (en) | Use of lactobacillus rhamnosus gg in combination with a long chain polyunsaturated fatty acid for the treatment, prevention or reduction of systemic inflammation in a formula-fed infant |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1501774 Country of ref document: EP |