ATE439598T1 - Chimäre zwischen einer alpha-kette eines humanen ige rezeptor und konstanten immunoglobulin- domänen von vögeln zur determination von serum ige. - Google Patents

Chimäre zwischen einer alpha-kette eines humanen ige rezeptor und konstanten immunoglobulin- domänen von vögeln zur determination von serum ige.

Info

Publication number
ATE439598T1
ATE439598T1 AT05022582T AT05022582T ATE439598T1 AT E439598 T1 ATE439598 T1 AT E439598T1 AT 05022582 T AT05022582 T AT 05022582T AT 05022582 T AT05022582 T AT 05022582T AT E439598 T1 ATE439598 T1 AT E439598T1
Authority
AT
Austria
Prior art keywords
chimera
bird
determination
immunoglobulin domain
alpha chain
Prior art date
Application number
AT05022582T
Other languages
English (en)
Inventor
Ingke Braren
Reinhard Bredehorst
Thomas Grunwald
Original Assignee
Pls Design Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pls Design Gmbh filed Critical Pls Design Gmbh
Application granted granted Critical
Publication of ATE439598T1 publication Critical patent/ATE439598T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/23—Immunoglobulins specific features characterized by taxonomic origin from birds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT05022582T 2005-10-17 2005-10-17 Chimäre zwischen einer alpha-kette eines humanen ige rezeptor und konstanten immunoglobulin- domänen von vögeln zur determination von serum ige. ATE439598T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05022582A EP1777524B1 (de) 2005-10-17 2005-10-17 Chimäre zwischen einer alpha-Kette eines humanen IgE Rezeptor und konstanten Immunoglobulin-Domänen von Vögeln zur Determination von Serum IgE.

Publications (1)

Publication Number Publication Date
ATE439598T1 true ATE439598T1 (de) 2009-08-15

Family

ID=35311875

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05022582T ATE439598T1 (de) 2005-10-17 2005-10-17 Chimäre zwischen einer alpha-kette eines humanen ige rezeptor und konstanten immunoglobulin- domänen von vögeln zur determination von serum ige.

Country Status (5)

Country Link
US (1) US7897153B1 (de)
EP (1) EP1777524B1 (de)
AT (1) ATE439598T1 (de)
DE (1) DE602005015981D1 (de)
DK (1) DK1777524T3 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2309263B1 (de) * 2009-09-14 2015-06-17 PLS-Design GmbH Chimerische IgYFc-Rezeptorkonstrukte
EP2494356B1 (de) * 2009-10-26 2017-03-15 Genentech, Inc. Assays für den nachweis von für therapeutische antikörper gegen ige spezifische antikörper und ihre verwendung in der anaphylaxe
US20110256641A1 (en) * 2010-04-19 2011-10-20 Michael Ling Methods and Systems for Detecting Free IgE
JP7127859B2 (ja) 2016-11-09 2022-08-30 ノース カロライナ ステート ユニバーシティ キメラタンパク質を用いたアレルギー疾患の治療
WO2019183437A1 (en) 2018-03-23 2019-09-26 North Carolina State University Methods and compositions for antibody to high affinity receptor for ige
CN110577598B (zh) * 2018-06-11 2022-03-08 李莉 抗sFcεRIα单克隆抗体及其应用
CN110305207B (zh) * 2019-06-14 2021-06-15 广州康盛生物科技股份有限公司 一种可溶性人IgE受体蛋白截短蛋白及其制备方法与应用
CN110672844A (zh) * 2019-10-29 2020-01-10 华中科技大学 一种新城疫病毒抗体磁免疫化学发光检测试剂盒及其应用
EP4306956A1 (de) * 2022-07-15 2024-01-17 Justus-Liebig-Universität Gießen Verfahren zum in-vitro nachweis antigen-spezifischer ige verursacht durch eine infektion mit parasiten oder pilzen
EP4689667A1 (de) * 2023-03-29 2026-02-11 CSL Behring AG Verfahren zur identifizierung von mit nebenwirkungen assoziiertem immunglobulin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5945294A (en) * 1996-11-26 1999-08-31 Heska Corporation Method to detect IgE
US6737056B1 (en) * 1999-01-15 2004-05-18 Genentech, Inc. Polypeptide variants with altered effector function
US6608172B1 (en) * 2000-06-09 2003-08-19 Good Biotech Corporation Isolation of IgY (ΔFc) antibodies
WO2003091285A1 (en) 2002-04-26 2003-11-06 Genpat77 Pharmacogenetics Ag Bispecific molecules for use in therapy and diagnosis of immune related and other diseases

Also Published As

Publication number Publication date
DE602005015981D1 (de) 2009-09-24
US7897153B1 (en) 2011-03-01
EP1777524A1 (de) 2007-04-25
EP1777524B1 (de) 2009-08-12
DK1777524T3 (da) 2009-12-14

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