ATE440537T1 - Vorrichtungen zum auffangen von interessierenden analyten in tränen - Google Patents

Vorrichtungen zum auffangen von interessierenden analyten in tränen

Info

Publication number
ATE440537T1
ATE440537T1 AT04719393T AT04719393T ATE440537T1 AT E440537 T1 ATE440537 T1 AT E440537T1 AT 04719393 T AT04719393 T AT 04719393T AT 04719393 T AT04719393 T AT 04719393T AT E440537 T1 ATE440537 T1 AT E440537T1
Authority
AT
Austria
Prior art keywords
interest
tears
devices
analytes
collecting analytes
Prior art date
Application number
AT04719393T
Other languages
English (en)
Inventor
Fiona Carney
Carol Morris
Yongxing Qiu
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of ATE440537T1 publication Critical patent/ATE440537T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/411—Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A61B2010/0067—Tear or lachrymal fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physiology (AREA)
  • Emergency Medicine (AREA)
  • Eyeglasses (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Farming Of Fish And Shellfish (AREA)
AT04719393T 2003-03-12 2004-03-11 Vorrichtungen zum auffangen von interessierenden analyten in tränen ATE440537T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45415003P 2003-03-12 2003-03-12
PCT/EP2004/002543 WO2004080297A1 (en) 2003-03-12 2004-03-11 Devices for collecting analytes of interest in tears

Publications (1)

Publication Number Publication Date
ATE440537T1 true ATE440537T1 (de) 2009-09-15

Family

ID=32990873

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04719393T ATE440537T1 (de) 2003-03-12 2004-03-11 Vorrichtungen zum auffangen von interessierenden analyten in tränen

Country Status (5)

Country Link
US (2) US20040181172A1 (de)
EP (1) EP1617757B1 (de)
AT (1) ATE440537T1 (de)
DE (1) DE602004022793D1 (de)
WO (1) WO2004080297A1 (de)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI255224B (en) * 2002-01-09 2006-05-21 Novartis Ag Polymeric articles having a lubricious coating and method for making the same
US7429465B2 (en) * 2002-09-13 2008-09-30 Novartis Ag Process for analyzing tear fluid
US20040181167A1 (en) * 2003-03-13 2004-09-16 Carney Fiona Patricia Method and kits for monitoring women's health
FR2881339B1 (fr) * 2005-02-02 2009-07-10 Commissariat Energie Atomique Dispositif de prelevement moleculaire par contact
US7795359B2 (en) * 2005-03-04 2010-09-14 Novartis Ag Continuous process for production of polymeric materials
FR2903590B1 (fr) * 2006-07-13 2013-05-10 Commissariat Energie Atomique Dispositif de prelevement cellulaire par contact
US8385998B2 (en) 2008-10-24 2013-02-26 Jin Zhang Contact lens integrated with a biosensor for the detection of glucose and other components in tears
WO2011097578A1 (en) * 2010-02-05 2011-08-11 Purdue Research Foundation Surface modification of surgical instruments for selective manipulation of biological tissues
WO2013137496A1 (ko) * 2012-03-14 2013-09-19 엘지전자 주식회사 눈물 추출 장치
US8798332B2 (en) 2012-05-15 2014-08-05 Google Inc. Contact lenses
US9523865B2 (en) 2012-07-26 2016-12-20 Verily Life Sciences Llc Contact lenses with hybrid power sources
US9158133B1 (en) 2012-07-26 2015-10-13 Google Inc. Contact lens employing optical signals for power and/or communication
US9298020B1 (en) 2012-07-26 2016-03-29 Verily Life Sciences Llc Input system
US8857981B2 (en) 2012-07-26 2014-10-14 Google Inc. Facilitation of contact lenses with capacitive sensors
US8919953B1 (en) 2012-08-02 2014-12-30 Google Inc. Actuatable contact lenses
US8971978B2 (en) 2012-08-21 2015-03-03 Google Inc. Contact lens with integrated pulse oximeter
US9696564B1 (en) 2012-08-21 2017-07-04 Verily Life Sciences Llc Contact lens with metal portion and polymer layer having indentations
US9111473B1 (en) 2012-08-24 2015-08-18 Google Inc. Input system
US9395468B2 (en) 2012-08-27 2016-07-19 Ocular Dynamics, Llc Contact lens with a hydrophilic layer
US8820934B1 (en) 2012-09-05 2014-09-02 Google Inc. Passive surface acoustic wave communication
US20140192315A1 (en) 2012-09-07 2014-07-10 Google Inc. In-situ tear sample collection and testing using a contact lens
US9398868B1 (en) 2012-09-11 2016-07-26 Verily Life Sciences Llc Cancellation of a baseline current signal via current subtraction within a linear relaxation oscillator-based current-to-frequency converter circuit
US10010270B2 (en) 2012-09-17 2018-07-03 Verily Life Sciences Llc Sensing system
US9326710B1 (en) 2012-09-20 2016-05-03 Verily Life Sciences Llc Contact lenses having sensors with adjustable sensitivity
US8870370B1 (en) 2012-09-24 2014-10-28 Google Inc. Contact lens that facilitates antenna communication via sensor impedance modulation
US8960898B1 (en) 2012-09-24 2015-02-24 Google Inc. Contact lens that restricts incoming light to the eye
US8989834B2 (en) 2012-09-25 2015-03-24 Google Inc. Wearable device
US20140088372A1 (en) 2012-09-25 2014-03-27 Google Inc. Information processing method
US8979271B2 (en) 2012-09-25 2015-03-17 Google Inc. Facilitation of temperature compensation for contact lens sensors and temperature sensing
US8821811B2 (en) * 2012-09-26 2014-09-02 Google Inc. In-vitro contact lens testing
US8960899B2 (en) 2012-09-26 2015-02-24 Google Inc. Assembling thin silicon chips on a contact lens
US9884180B1 (en) 2012-09-26 2018-02-06 Verily Life Sciences Llc Power transducer for a retinal implant using a contact lens
US20140088381A1 (en) * 2012-09-26 2014-03-27 Google Inc. Facilitation of tear sample collection and testing using a contact lens
US8985763B1 (en) 2012-09-26 2015-03-24 Google Inc. Contact lens having an uneven embedded substrate and method of manufacture
US9063351B1 (en) 2012-09-28 2015-06-23 Google Inc. Input detection system
US8965478B2 (en) 2012-10-12 2015-02-24 Google Inc. Microelectrodes in an ophthalmic electrochemical sensor
US9176332B1 (en) 2012-10-24 2015-11-03 Google Inc. Contact lens and method of manufacture to improve sensor sensitivity
US9757056B1 (en) 2012-10-26 2017-09-12 Verily Life Sciences Llc Over-molding of sensor apparatus in eye-mountable device
US8874182B2 (en) 2013-01-15 2014-10-28 Google Inc. Encapsulated electronics
US9289954B2 (en) 2013-01-17 2016-03-22 Verily Life Sciences Llc Method of ring-shaped structure placement in an eye-mountable device
US20140209481A1 (en) 2013-01-25 2014-07-31 Google Inc. Standby Biasing Of Electrochemical Sensor To Reduce Sensor Stabilization Time During Measurement
US9636016B1 (en) 2013-01-25 2017-05-02 Verily Life Sciences Llc Eye-mountable devices and methods for accurately placing a flexible ring containing electronics in eye-mountable devices
US9289623B2 (en) * 2013-03-15 2016-03-22 Johnson & Johnson Vision Care, Inc. Method and device for monitoring and treatment of seasonal affective disorder
US9161712B2 (en) 2013-03-26 2015-10-20 Google Inc. Systems and methods for encapsulating electronics in a mountable device
US9113829B2 (en) 2013-03-27 2015-08-25 Google Inc. Systems and methods for encapsulating electronics in a mountable device
US20140371560A1 (en) 2013-06-14 2014-12-18 Google Inc. Body-Mountable Devices and Methods for Embedding a Structure in a Body-Mountable Device
US9084561B2 (en) 2013-06-17 2015-07-21 Google Inc. Symmetrically arranged sensor electrodes in an ophthalmic electrochemical sensor
US9948895B1 (en) 2013-06-18 2018-04-17 Verily Life Sciences Llc Fully integrated pinhole camera for eye-mountable imaging system
US9685689B1 (en) 2013-06-27 2017-06-20 Verily Life Sciences Llc Fabrication methods for bio-compatible devices
US9307901B1 (en) 2013-06-28 2016-04-12 Verily Life Sciences Llc Methods for leaving a channel in a polymer layer using a cross-linked polymer plug
US9028772B2 (en) 2013-06-28 2015-05-12 Google Inc. Methods for forming a channel through a polymer layer using one or more photoresist layers
US9814387B2 (en) 2013-06-28 2017-11-14 Verily Life Sciences, LLC Device identification
US9492118B1 (en) 2013-06-28 2016-11-15 Life Sciences Llc Pre-treatment process for electrochemical amperometric sensor
US9636050B1 (en) 2013-11-07 2017-05-02 Verily Life Sciences Llc Methods and apparatus for forming a channel through a polymer layer using a protrusion
CN105917270A (zh) 2013-11-15 2016-08-31 视觉力学有限责任公司 具有亲水层的接触透镜
US9654674B1 (en) 2013-12-20 2017-05-16 Verily Life Sciences Llc Image sensor with a plurality of light channels
US9572522B2 (en) 2013-12-20 2017-02-21 Verily Life Sciences Llc Tear fluid conductivity sensor
US9366570B1 (en) 2014-03-10 2016-06-14 Verily Life Sciences Llc Photodiode operable in photoconductive mode and photovoltaic mode
US9184698B1 (en) 2014-03-11 2015-11-10 Google Inc. Reference frequency from ambient light signal
US9789655B1 (en) 2014-03-14 2017-10-17 Verily Life Sciences Llc Methods for mold release of body-mountable devices including microelectronics
US10232531B1 (en) 2014-07-08 2019-03-19 Verily Life Sciences Llc Methods and apparatus for forming a polymer layer around a structure using a plurality of protrusions
US10309975B2 (en) * 2014-08-21 2019-06-04 University Of Central Florida Research Foundation, Inc. Functionalized eyewear device for detecting biomarker in tears
US9907498B2 (en) 2014-09-04 2018-03-06 Verily Life Sciences Llc Channel formation
US9459201B2 (en) 2014-09-29 2016-10-04 Zyomed Corp. Systems and methods for noninvasive blood glucose and other analyte detection and measurement using collision computing
JP6774947B2 (ja) 2014-12-09 2020-10-28 タンジブル サイエンス インコーポレイテッド 生体適合性層を有する医療デバイスコーティング
EP3291886A1 (de) * 2015-05-04 2018-03-14 Ecole Polytechnique Federale de Lausanne (EPFL) Ophthalmische kontaktlinse mit komprimierbarer affinitätsmatrix
US10135076B1 (en) 2015-05-05 2018-11-20 Verily Life Sciences Llc Tear-activated micro-battery for use on smart contact lenses
WO2017114398A1 (en) * 2015-12-27 2017-07-06 Tsinghua-Berkeley Shenzhen Institute Compositions of diagnostic contact lenses and uses thereof
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
JP7038111B2 (ja) 2016-09-20 2022-03-17 アルコン インク． ヒドロゲルコンタクトレンズ上に潤滑性コーティングを有するヒドロゲルコンタクトレンズ
US12064237B2 (en) 2018-03-13 2024-08-20 Menicon Co., Ltd. Determination system, computing device, determination method, and program
WO2020185689A1 (en) * 2019-03-08 2020-09-17 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Multilayer drug delivery coating for contact lens
WO2021033789A1 (en) * 2019-08-19 2021-02-25 Nexmos Co., Ltd. An aptamer-functionalized contact lens and an early diagnosis method of disease using the same
EP4120959A4 (de) * 2020-05-01 2023-08-16 Teardx LLC Augeneinsätze mit analyteneinfang- und trennmitteln
CA3182679A1 (en) 2020-05-07 2021-11-11 Calm Water Therapeutics Llc Methods for using bioadhesive and steric interactions of copolymers with at least two moieties to minimize adverse effects mediated by external influences on cell, tissue, organ system, and organism biology
CN119104738B (zh) * 2024-11-08 2025-02-11 四川大学华西医院 一种基于纳米酶信号放大的检测装置及其使用方法和应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US192657A (en) * 1877-07-03 Improvement in sand-core boxes
US45783A (en) * 1865-01-03 Improved stove
DE3218999C1 (de) * 1982-05-19 1983-12-15 Peter 8750 Aschaffenburg Höfer Vorrichtung zur Untersuchung von Tränenflüssigkeit
DE3243339C2 (de) * 1982-11-19 1986-03-27 Helmut Dr.med. 2000 Hamburg Opel Verfahren zur Gewinnung von Tränenflüssigkeit
EP0236023A3 (de) 1986-03-03 1988-09-07 Seymour Norman Blackman Nicht-eindringendes Verfahren zum Messen des Blut-Glucose-Spiegels
GB9217808D0 (en) 1992-08-21 1992-10-07 Unilever Plc Advisory method
GB9217866D0 (en) 1992-08-21 1992-10-07 Unilever Plc Monitoring method
US5352411A (en) 1993-08-13 1994-10-04 Khuri Raja N Device for determination of tear constituents
DE4335961A1 (de) * 1993-10-21 1995-04-27 Behringwerke Ag Probenabnahmebesteck zur Gewinnung von Tränenflüssigkeit
EP0728310B1 (de) 1993-11-12 1999-08-04 Unipath Limited Nachweisverfahren und vorrichtung dafür
GB9419267D0 (en) 1994-09-23 1994-11-09 Unilever Plc Assay devices
ATE210298T1 (de) 1994-09-23 2001-12-15 Unilever Nv Überwachungsverfahren und dazu verwendbare vorrichtungen
US6060256A (en) * 1997-12-16 2000-05-09 Kimberly-Clark Worldwide, Inc. Optical diffraction biosensor
US6451871B1 (en) * 1998-11-25 2002-09-17 Novartis Ag Methods of modifying surface characteristics
US6131580A (en) * 1998-04-17 2000-10-17 The University Of Washington Template imprinted materials by RFGD plasma deposition
CA2381520C (en) * 1999-08-26 2009-05-26 Novartis Ag Ocular analyte sensor
US20020007113A1 (en) * 1999-08-26 2002-01-17 March Wayne Front Ocular analyte sensor
TW434854B (en) * 1999-11-09 2001-05-16 Advanced Semiconductor Eng Manufacturing method for stacked chip package
US20020192657A1 (en) * 2001-06-19 2002-12-19 Erwin Robert L. Bio-tolerant substrata having analyte binding microarray

Also Published As

Publication number Publication date
EP1617757A1 (de) 2006-01-25
US20040181172A1 (en) 2004-09-16
US20080139963A1 (en) 2008-06-12
DE602004022793D1 (de) 2009-10-08
EP1617757B1 (de) 2009-08-26
WO2004080297A1 (en) 2004-09-23

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