ATE440829T1 - Schwefel-enthaltende proanthocyanidin-oligomer- zusammensetzung und verfahren zu deren herstellung - Google Patents

Schwefel-enthaltende proanthocyanidin-oligomer- zusammensetzung und verfahren zu deren herstellung

Info

Publication number: ATE440829T1
Authority: AT; Austria
Prior art keywords: proanthocyanidine; production; sulfur containing; oligomer composition; sulfur
Prior art date: 2003-05-26

Application number

AT04745437T

Other languages

English (en)

Inventor

Gen-Ichiro Nonaka

Buxiang Sun

Lan Yuan

Takashi Nakagawa

Hajime Fujii

Young-Joon Surh

Original Assignee

Amino Up Chemical Co Ltd

Usaien Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-05-26

Filing date

2004-05-25

Publication date

2009-09-15

2004-05-25 Application filed by Amino Up Chemical Co Ltd, Usaien Pharmaceutical Co Ltd filed Critical Amino Up Chemical Co Ltd

2009-09-15 Application granted granted Critical

2009-09-15 Publication of ATE440829T1 publication Critical patent/ATE440829T1/de

Links

NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 title abstract 3
229910052717 sulfur Inorganic materials 0.000 title abstract 3
239000011593 sulfur Substances 0.000 title abstract 3
239000000203 mixture Substances 0.000 title abstract 2
JPFCOVZKLAXXOE-XBNSMERZSA-N (3r)-2-(3,5-dihydroxy-4-methoxyphenyl)-8-[(2r,3r,4r)-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2h-chromen-4-yl]-3,4-dihydro-2h-chromene-3,5,7-triol Chemical compound C1=C(O)C(OC)=C(O)C=C1C1[C@H](O)CC(C(O)=CC(O)=C2[C@H]3C4=C(O)C=C(O)C=C4O[C@@H]([C@@H]3O)C=3C=CC(O)=CC=3)=C2O1 JPFCOVZKLAXXOE-XBNSMERZSA-N 0.000 abstract 3
229920001991 Proanthocyanidin Polymers 0.000 abstract 3
208000014644 Brain disease Diseases 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
230000032683 aging Effects 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
235000013402 health food Nutrition 0.000 abstract 1
210000000936 intestine Anatomy 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
- C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Botany (AREA)
Mycology (AREA)
Biomedical Technology (AREA)
Food Science & Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Nutrition Science (AREA)
Polymers & Plastics (AREA)
Heart & Thoracic Surgery (AREA)
Biotechnology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Cardiology (AREA)
Psychiatry (AREA)
Alternative & Traditional Medicine (AREA)
Hospice & Palliative Care (AREA)
Medical Informatics (AREA)
Microbiology (AREA)
Natural Medicines & Medicinal Plants (AREA)
Epidemiology (AREA)

AT04745437T 2003-05-26 2004-05-25 Schwefel-enthaltende proanthocyanidin-oligomer- zusammensetzung und verfahren zu deren herstellung ATE440829T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP2003148276		2003-05-26
JP2004017113		2004-01-26
PCT/JP2004/007448 WO2004103988A1 (ja)	2003-05-26	2004-05-25	含硫プロアントシアニジンオリゴマー組成物及びその製造方法

Publications (1)

Publication Number	Publication Date
ATE440829T1 true ATE440829T1 (de)	2009-09-15

Family

ID=33479002

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04745437T ATE440829T1 (de)	2003-05-26	2004-05-25	Schwefel-enthaltende proanthocyanidin-oligomer- zusammensetzung und verfahren zu deren herstellung

Country Status (13)

Country	Link
US (3)	US7833553B2 (de)
EP (1)	EP1524270B1 (de)
JP (1)	JP5004265B2 (de)
KR (1)	KR101241534B1 (de)
CN (1)	CN102178673B (de)
AT (1)	ATE440829T1 (de)
AU (1)	AU2004240219C1 (de)
CA (1)	CA2488394C (de)
DE (1)	DE602004022758D1 (de)
ES (1)	ES2330746T3 (de)
MX (1)	MXPA04012598A (de)
NZ (2)	NZ536591A (de)
WO (1)	WO2004103988A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2599295C (en)	2005-02-25	2014-10-14	Nagasaki University	Method of producing proanthocyanidin oligomer
US7671007B2 (en)	2006-05-04	2010-03-02	Conopco, Inc.	Personal care compositions comprising hydrophobically modified cationic polymers
JP2007314483A (ja) *	2006-05-29	2007-12-06	Ichimaru Pharcos Co Ltd	外用製剤並びに外用製剤の製造方法
JP2008156265A (ja) *	2006-12-22	2008-07-10	Yamagata Prefecture	Ａ型プロアントシアニジンオリゴマー画分及びその製造方法
JP2008184389A (ja) *	2007-01-26	2008-08-14	Asahi Breweries Ltd	新規フラバノール化合物及びその製造方法
WO2011073950A1 (en) *	2009-12-17	2011-06-23	National University Of Singapore	Method of preparing derivatives/oligomers of epicatechin and applications thereof
JP5437537B1 (ja) *	2012-10-05	2014-03-12	フジッコ株式会社	低重合度プロアントシアニジンの製法
FR3024452B1 (fr) *	2014-08-04	2016-08-19	Agronomique Inst Nat Rech	Composes derives de flavanoides et procede pour leur preparation par depolymerisation de tanins condenses
JP6667773B1 (ja) *	2018-12-20	2020-03-18	公益財団法人佐賀県地域産業支援センター	炎症性サイトカイン産生抑制用の組成物
JP7334104B2 (ja) *	2019-10-31	2023-08-28	エステー株式会社	認知症改善および／または予防剤
EP4271210B1 (de) *	2020-12-30	2024-10-30	Distillerie Bonollo Umberto - S.p.A. Con Sigla "U.B. S.p.A."	Verfahren zur herstellung von traubenkernextrakten und die so gewonnenen extrakte

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH07238079A (ja) *	1994-02-25	1995-09-12	Lotte Co Ltd	カテキン化合物、その製造方法およびこれを用いる消臭剤
JPH1059846A (ja) *	1996-06-10	1998-03-03	Kikkoman Corp	白内障の予防または治療薬剤
JP3977889B2 (ja)	1997-02-07	2007-09-19	株式会社アミノアップ化学	蕎麦殻抽出物を有効成分とする薬剤
US6207842B1 (en) *	1997-10-09	2001-03-27	Mars Incorporated	Process for preparing procyanidin(4-6 or 4-8) oligomers and their derivatives
ES2184640B1 (es)	2001-09-17	2004-08-16	Consejo Superior Investigaciones Cientificas	Conjugados de flavanoles y cisteina.
CA2497087A1 (en)	2004-03-09	2005-09-09	Commonwealth Scientific And Industrial Research Organisation	Novel genes encoding proteins involved in proanthocyanidin synthesis

2004
- 2004-05-25 ES ES04745437T patent/ES2330746T3/es not_active Expired - Lifetime
- 2004-05-25 NZ NZ536591A patent/NZ536591A/en not_active IP Right Cessation
- 2004-05-25 NZ NZ567835A patent/NZ567835A/en not_active IP Right Cessation
- 2004-05-25 EP EP04745437A patent/EP1524270B1/de not_active Expired - Lifetime
- 2004-05-25 AU AU2004240219A patent/AU2004240219C1/en not_active Ceased
- 2004-05-25 KR KR1020047018959A patent/KR101241534B1/ko not_active Expired - Fee Related
- 2004-05-25 AT AT04745437T patent/ATE440829T1/de not_active IP Right Cessation
- 2004-05-25 CA CA2488394A patent/CA2488394C/en not_active Expired - Lifetime
- 2004-05-25 JP JP2005506438A patent/JP5004265B2/ja not_active Expired - Lifetime
- 2004-05-25 US US10/513,950 patent/US7833553B2/en not_active Expired - Lifetime
- 2004-05-25 WO PCT/JP2004/007448 patent/WO2004103988A1/ja not_active Ceased
- 2004-05-25 CN CN201110070589.9A patent/CN102178673B/zh not_active Expired - Fee Related
- 2004-05-25 MX MXPA04012598A patent/MXPA04012598A/es active IP Right Grant
- 2004-05-25 DE DE602004022758T patent/DE602004022758D1/de not_active Expired - Lifetime
2010
- 2010-10-06 US US12/898,946 patent/US8088419B2/en not_active Expired - Fee Related
- 2010-10-06 US US12/898,926 patent/US7939116B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JPWO2004103988A1 (ja)	2006-07-20
NZ536591A (en)	2008-07-31
AU2004240219B8 (en)	2010-06-03
EP1524270A4 (de)	2006-09-13
ES2330746T3 (es)	2009-12-15
EP1524270B1 (de)	2009-08-26
NZ567835A (en)	2008-10-31
US20110021792A1 (en)	2011-01-27
MXPA04012598A (es)	2005-07-01
US8088419B2 (en)	2012-01-03
CA2488394A1 (en)	2004-12-02
KR101241534B1 (ko)	2013-03-08
KR20060029999A (ko)	2006-04-07
EP1524270A1 (de)	2005-04-20
AU2004240219B2 (en)	2010-05-27
CN102178673B (zh)	2015-08-19
WO2004103988A1 (ja)	2004-12-02
CN102178673A (zh)	2011-09-14
AU2004240219A1 (en)	2005-02-03
US20050261198A1 (en)	2005-11-24
US7939116B2 (en)	2011-05-10
AU2004240219A8 (en)	2008-09-11
CA2488394C (en)	2013-09-24
JP5004265B2 (ja)	2012-08-22
DE602004022758D1 (de)	2009-10-08
US20110028742A1 (en)	2011-02-03
AU2004240219C1 (en)	2010-06-17
US7833553B2 (en)	2010-11-16

Legal Events

Date	Code	Title	Description
2010-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
CY1109420T1 (el)	2014-08-13	Ενωσεις εστερα ν-αλκυλκαρβονυλ-αμινοξεος και ν-αλκυλκαρβονυλ-αμινο λακτονης και χρηση αυτων
DE602004022758D1 (de)	2009-10-08	Schwefel-enthaltende proanthocyanidin-oligomer-zusammensetzung und verfahren zu deren herstellung
NO20042150L (no)	2004-09-03	Naeringsmiddel- eller dyrefôrsammensetning som innheholder planteekstrakt for benhelsen
DE602004027476D1 (de)	2010-07-15	Zusammensetzungen und formulierungsverfahren für enteralprodukte, die sialsäure enthalten
WO2008028631A3 (en)	2008-06-05	Skin care composition
PA8618801A1 (es)	2005-09-28	Compuestos de fertilizante para simular la absorcion de sustancias nutritivas en plantas.
MXPA05008993A (es)	2005-10-18	Derivados de diarilcicloalquilo, metodo para su produccion y su uso como medicamentos.
ATE406154T1 (de)	2008-09-15	Zusammensetzung enthaltend ozonisierte öle und/oder andere natürliche und/oder synthetische ozonizierte produkte und ihre verwendung in pharmazeutischen, kosmetischen, diätetischen oder nahrungsergänzenden zusammensetzungen in human- und veterinärgebieten
ATE406884T1 (de)	2008-09-15	Zusammensetzungen mit pantothensäure oder derivaten davon und ihre verwendung zur stimulierung des appetits
ATE372776T1 (de)	2007-09-15	Arzneimittel enthaltend deuterium zur behandlung der zuckerkrankheit
EP1952701A3 (de)	2011-06-08	Verbesserung der Langlebigkeit und der Bedingungen älterer Katzen
ATE344262T1 (de)	2006-11-15	2-heteroarylcarbonsäureamide
DE602005010876D1 (de)	2008-12-18	Neuartige biaromatische ppar-rezeptoren aktivierende zusammensetzungen und ihre verwendung in kosmetischen oder pharmazeutischen zusammensetzungen
DE602005023463D1 (de)	2010-10-21	Verwendung von milchsäurebakterien zur verringerung von zahnfleischbluten und mundentzündung
ATE367167T1 (de)	2007-08-15	Aufbereitung von aldesleukin zur pharmazeutischen verwendung
PT1749517E (pt)	2008-09-29	Composição farmacêutica estável compreendendo a forma iv de linezolida
ATE435864T1 (de)	2009-07-15	Substituierte 5,6,7,8-tetrahydro-imidazoä1 ,2- aüpyridin-2-ylamin-verbindungen und deren verwendung zur herstellung von arzneimitteln
DE602004030781D1 (de)	2011-02-10	Gefriergetrocknetes präparat mit methylcobalamin und verfahren zu seiner herstellung
ATE419012T1 (de)	2009-01-15	Verwendung von 2,5-dihydroxybenzolsulfonsäure- derivaten bei der herstellung eines medikaments zur verstärkung der wirkung anderer arzneimittel zur behandlung der erektilen dysfunktion
BR0312318A (pt)	2005-04-12	Compostos, uso de um ou mais compostos, composição farmacêutica, composição cosmética e usos cosméticos
WO2008078453A1 (ja)	2008-07-03	血小板産生促進因子及びその利用
DE60311304D1 (de)	2007-03-08	Aufgeschlagene süssware mit hohem gehalt an festen fruchtbestandteilen und methode zu deren herstellung
MXPA05008990A (es)	2005-10-18	Derivados de acido alcanoico sustituido con cicloalquilo, metodos para su produccion y su uso como medicamentos.
DE60311351D1 (de)	2007-03-15	Verwendung von Zeoliten zur Herstellung oraler Zubereitungen zur Behandlung von Vergiftung
ATE308989T1 (de)	2005-11-15	Zubereitung für oral zu verabreichende nahrungsergänzungs- und/oder arznelmittel in form von tabletten