ATE441706T1 - Konjugate mit biologisch abbaubarem polymer und verwendung dafür - Google Patents
Konjugate mit biologisch abbaubarem polymer und verwendung dafürInfo
- Publication number
- ATE441706T1 ATE441706T1 AT03716070T AT03716070T ATE441706T1 AT E441706 T1 ATE441706 T1 AT E441706T1 AT 03716070 T AT03716070 T AT 03716070T AT 03716070 T AT03716070 T AT 03716070T AT E441706 T1 ATE441706 T1 AT E441706T1
- Authority
- AT
- Austria
- Prior art keywords
- biodegradable polymer
- polymer
- apyrase
- polymer conjugates
- biologically active
- Prior art date
Links
- 229920002988 biodegradable polymer Polymers 0.000 title abstract 2
- 239000004621 biodegradable polymer Substances 0.000 title abstract 2
- 102000007347 Apyrase Human genes 0.000 abstract 2
- 108010007730 Apyrase Proteins 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 208000037260 Atherosclerotic Plaque Diseases 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000019553 vascular disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L59/00—Compositions of polyacetals; Compositions of derivatives of polyacetals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Polymers & Plastics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Biological Depolymerization Polymers (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35830302P | 2002-02-20 | 2002-02-20 | |
| PCT/US2003/004845 WO2003070823A2 (en) | 2002-02-20 | 2003-02-19 | Conjugates comprising a biodegradable polymer and uses therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE441706T1 true ATE441706T1 (de) | 2009-09-15 |
Family
ID=27757725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03716070T ATE441706T1 (de) | 2002-02-20 | 2003-02-19 | Konjugate mit biologisch abbaubarem polymer und verwendung dafür |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7785618B2 (de) |
| EP (2) | EP2138575B8 (de) |
| AT (1) | ATE441706T1 (de) |
| AU (1) | AU2003219796A1 (de) |
| DE (1) | DE60329126D1 (de) |
| WO (1) | WO2003070823A2 (de) |
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-
2003
- 2003-02-19 AT AT03716070T patent/ATE441706T1/de not_active IP Right Cessation
- 2003-02-19 AU AU2003219796A patent/AU2003219796A1/en not_active Abandoned
- 2003-02-19 WO PCT/US2003/004845 patent/WO2003070823A2/en not_active Ceased
- 2003-02-19 EP EP09011078.4A patent/EP2138575B8/de not_active Expired - Lifetime
- 2003-02-19 EP EP03716070A patent/EP1585817B1/de not_active Expired - Lifetime
- 2003-02-19 DE DE60329126T patent/DE60329126D1/de not_active Expired - Lifetime
-
2004
- 2004-08-20 US US10/922,378 patent/US7785618B2/en not_active Expired - Fee Related
-
2010
- 2010-08-27 US US12/870,030 patent/US20110044967A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003070823A3 (en) | 2004-08-26 |
| US7785618B2 (en) | 2010-08-31 |
| DE60329126D1 (de) | 2009-10-15 |
| WO2003070823A2 (en) | 2003-08-28 |
| EP1585817A2 (de) | 2005-10-19 |
| EP1585817A4 (de) | 2005-12-28 |
| US20110044967A1 (en) | 2011-02-24 |
| AU2003219796A8 (en) | 2003-09-09 |
| EP1585817B1 (de) | 2009-09-02 |
| EP2138575B1 (de) | 2013-06-19 |
| EP2138575A1 (de) | 2009-12-30 |
| US20050169968A1 (en) | 2005-08-04 |
| EP2138575B8 (de) | 2013-07-24 |
| WO2003070823A9 (en) | 2005-06-02 |
| AU2003219796A1 (en) | 2003-09-09 |
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| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |