ATE441724T1 - Neue polynukleotide - Google Patents

Neue polynukleotide

Info

Publication number
ATE441724T1
ATE441724T1 AT00127688T AT00127688T ATE441724T1 AT E441724 T1 ATE441724 T1 AT E441724T1 AT 00127688 T AT00127688 T AT 00127688T AT 00127688 T AT00127688 T AT 00127688T AT E441724 T1 ATE441724 T1 AT E441724T1
Authority
AT
Austria
Prior art keywords
fragments
polynucleotides
new polynucleotides
polynucleotide
readable
Prior art date
Application number
AT00127688T
Other languages
English (en)
Inventor
Satochi Nakagawa
Hiroshi Mizoguchi
Seiko Ando
Mikiro Hayashi
Keiko Ochiai
Haruhiko Yokoi
Naoko Tateishi
Akihiro Senoh
Masato Ikeda
Akio Ozaki
Original Assignee
Kyowa Hakko Bio Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Bio Co Ltd filed Critical Kyowa Hakko Bio Co Ltd
Application granted granted Critical
Publication of ATE441724T1 publication Critical patent/ATE441724T1/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
    • C12N15/03—Bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01003—Homoserine dehydrogenase (1.1.1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y604/00—Ligases forming carbon-carbon bonds (6.4)
    • C12Y604/01—Ligases forming carbon-carbon bonds (6.4.1)
    • C12Y604/01001—Pyruvate carboxylase (6.4.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15—Corynebacterium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT00127688T 1999-12-16 2000-12-18 Neue polynukleotide ATE441724T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP37748499 1999-12-16
JP2000159162 2000-04-07
JP2000280988 2000-08-03

Publications (1)

Publication Number Publication Date
ATE441724T1 true ATE441724T1 (de) 2009-09-15

Family

ID=27341889

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00127688T ATE441724T1 (de) 1999-12-16 2000-12-18 Neue polynukleotide

Country Status (6)

Country Link
US (2) US20020197605A1 (de)
EP (2) EP2107128B1 (de)
JP (1) JP4623825B2 (de)
KR (2) KR100961398B1 (de)
AT (1) ATE441724T1 (de)
DE (1) DE60042872D1 (de)

Families Citing this family (427)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7892798B2 (en) 1999-06-25 2011-02-22 Evonik Degussa Gmbh Nucleic acid molecules encoding metabolic regulatory proteins from Corynebacterium glutamicum, useful for increasing the production of methionone by a microorganism
EP1683859A3 (de) * 1999-06-25 2006-08-02 Basf Aktiengesellschaft Mögliches Catechol 1,2-Dioxygenase Gen aus Corynebacterium glutamicum
EP1634952A3 (de) * 1999-06-25 2006-03-29 BASF Aktiengesellschaft Gene kodierende für proteine aus corynebacterium glutamicum, die an der homöostase und adaptierung beteiligt sind
US7270984B1 (en) * 1999-06-25 2007-09-18 Basf Aktiengesellschaft Polynucleotides encoding a 6-phosphogluconolactonase polypeptide from corynebacterium glutamicum
KR100878336B1 (ko) * 1999-06-25 2009-01-14 백광산업 주식회사 탄소 대사 및 에너지 생산과 관련된 단백질을 코딩하는코리네박테리움 글루타미쿰 유전자
MXPA01012932A (es) * 1999-07-01 2002-07-30 Basf Ag Genes de corynebacterium glutamicum que codifican proteinas de sistema de fosfoenolpiruvato: azucar fosfotransferasa.
AU781091B2 (en) * 1999-07-02 2005-05-05 Ajinomoto Co., Inc. DNA encoding sucrose PTS enzyme II
US20020086371A1 (en) 1999-07-07 2002-07-04 Degussa-Huls Aktiengesellschaft L-lysine-producing corynebacteria and process for the preparation of L-lysine
US6797509B1 (en) 1999-07-09 2004-09-28 Degussa-Huls Ag Nucleotide sequences which code for the tal gene
US20060014259A9 (en) * 1999-07-09 2006-01-19 Kevin Burke Process for the preparation of L-amino acids with amplification of the zwf gene
ID29569A (id) 1999-07-09 2001-09-06 Degussa Ag Cs Urutan nucleotida yang menyandi gen opca
US6569650B1 (en) * 1999-08-13 2003-05-27 Degussa Ag Process for the fermentative preparation of metabolic products and for the nucleotide sequences encoding for the sod gene
DE19943587A1 (de) 1999-09-11 2001-03-15 Degussa Neue für das dapF-Gen codierende Nukleotidsequenzen
US6586214B1 (en) * 1999-09-15 2003-07-01 Degussa Ag Method for increasing the metabolic flux through the pentose phosphate cycle in coryneform bacteria by regulation of the phosphoglucose isomerase (pgi gene)
US6872553B2 (en) 1999-10-20 2005-03-29 Degussa Ag Nucleotide sequences which code for the pck gene
DE19950409A1 (de) 1999-10-20 2001-04-26 Degussa Neue für das pck-Gen codierende Nukleotidsequenzen
DE19951708A1 (de) * 1999-10-27 2001-05-03 Degussa Für den Export verzweigtkettiger Aminosäuren kodierende Nikleotidsequenzen, Verfahren zu deren Isolierung und ihre Verwendung
CA2392000A1 (en) 1999-11-19 2001-05-31 Kyowa Hakko Kogyo Co., Ltd. Glmu polypeptide and dna encoding for the polypeptide
EP1106622A3 (de) * 1999-11-23 2004-01-02 Degussa AG Neue für das pfkA-Gen codierende Nukleotidsequenzen
DE19958160A1 (de) 1999-12-02 2001-06-07 Degussa Neue für das gpm-Gen codierende Nukleotidsequenzen
DE19958159A1 (de) 1999-12-02 2001-06-07 Degussa Neue für das glk-Gen codierende Nukleotidsequenzen
CN1230525C (zh) * 1999-12-24 2005-12-07 味之素株式会社 生产l－氨基酸的方法和新型基因
US6927046B1 (en) * 1999-12-30 2005-08-09 Archer-Daniels-Midland Company Increased lysine production by gene amplification using coryneform bacteria
DE10001101A1 (de) * 2000-01-13 2001-07-19 Degussa Neue für das ptsH-Gen codierende Nukleotidsequenzen
DE10044831A1 (de) 2000-03-01 2002-04-04 Forschungszentrum Juelich Gmbh Verbessertes Verfahren zur mikrobiellen Herstellung von L-Serin sowie ein dazu geeigneter genetisch veränderter Mikroorganismus
CA2402186C (en) * 2000-03-09 2011-04-05 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding metabolic pathway proteins
SK287997B6 (sk) * 2000-03-20 2012-09-03 Evonik Degussa Gmbh Isolated gene of Corynebacterium glutamicum, recombinant coryneform bacteria and process for preparation of L-lysine or L-threonine
US20050112733A1 (en) * 2000-03-20 2005-05-26 Degussa Ag Process for the preparation of L-amino acids with amplification of the zwf gene
DE10014546A1 (de) * 2000-03-23 2001-09-27 Degussa Für das dapC-Gen kodierende Nukleotidsequenzen und Verfahren zur Herstellung von L-Lysin
DE10021828A1 (de) * 2000-05-04 2001-11-08 Degussa Neue für das cdsA-Gen kodierende Nukleotidsequenzen
US6949374B2 (en) 2000-05-04 2005-09-27 Degussa Ag FadD15 gene of Corynebacterium glutamicum, encoding an acyl-CoA synthase polypeptide
DE10021829A1 (de) * 2000-05-04 2001-11-08 Degussa Neue für das pgsA2-Gen kodierende Nukleotidsequenzen
DE10021831A1 (de) * 2000-05-04 2001-11-08 Degussa Neue für das fadD15-Gen kodierende Nukleotidsequenzen
DE10021832A1 (de) * 2000-05-04 2001-11-08 Degussa Neue für das cma-Gen kodierende Nukleotidsequenzen
US6562607B2 (en) 2000-05-04 2003-05-13 Degussa-Huls Aktiengesellschaft Nucleotide sequences coding for the cls gene
DE10021826A1 (de) * 2000-05-04 2001-11-08 Degussa Neue für das cls-Gen kodierende Nukleotidsequenzen
DE10023400A1 (de) * 2000-05-12 2001-11-15 Degussa Neue für das acp-Gen kodierende Nukleotidsequenzen
US6586229B1 (en) 2000-06-01 2003-07-01 North Carolina State University Method for the production of ρ-Hydroxybenzoate in species of pseudomonas and agrobacterium
US20020081673A1 (en) 2000-06-02 2002-06-27 Bettina Mockel Novel nucleotide sequences coding for the glbO gene
DE10032173A1 (de) 2000-07-01 2002-01-17 Degussa Neue für das plsC-Gen kodierende Nukleotidsequenzen
DE10032350A1 (de) 2000-07-04 2002-01-24 Degussa Neue für das mdhA-Gen kodierende Nukleotidsequenzen
JP4304837B2 (ja) * 2000-07-05 2009-07-29 味の素株式会社 Ｌ−グルタミン酸生産菌及びｌ−グルタミン酸の製造法
EP1174520A3 (de) * 2000-07-18 2004-02-18 Degussa AG Verfahren zur Uberwachung einer Gärung mit hilfe eines expressions Array
WO2002010209A1 (en) * 2000-08-02 2002-02-07 Degussa Ag Nucleotide sequences which code for the meth gene
JP2004527210A (ja) 2000-08-02 2004-09-09 ザ ジョンズ ホプキンス ユニバーシティー 内皮細胞発現パターンの評価法
EP1307476A1 (de) * 2000-08-02 2003-05-07 Degussa AG Nukleotidsequenzen die für das mete-gen kodieren
US6958228B2 (en) 2000-08-02 2005-10-25 Degussa Ag Nucleotide sequence which code for the metH gene
EP1307563B1 (de) * 2000-08-10 2004-08-18 Degussa AG Nukleotid sequenzen kodierend für das lysr2 gen
WO2002012505A1 (en) * 2000-08-10 2002-02-14 Degussa Ag Nucleotide sequences which code for the lysr3 gene
DE10039044A1 (de) * 2000-08-10 2002-02-21 Degussa Neue für das IysR1-Gen kodierende Nukleotidsequenzen
DE10110346A1 (de) * 2000-08-10 2002-02-21 Degussa Neue für das IysR2-Gen kodierende Nukleotidsequenzen
DE10039043A1 (de) * 2000-08-10 2002-02-21 Degussa Neue für das luxR-Gen kodierende Nukleotidsequenzen
DE10039049A1 (de) 2000-08-10 2002-02-21 Degussa Neue für das IysR3-Gen kodierende Nukleotidsequenzen
EP1313759A1 (de) * 2000-08-26 2003-05-28 Degussa AG Nukleotidsequenzen die das ccpa2 gen kodieren
DE10042051A1 (de) * 2000-08-26 2002-03-07 Degussa Neue für das cstA-Gen kodierende Nukleotidsequenzen
US6916636B2 (en) * 2000-08-26 2005-07-12 Degussa Ag Nucleotide sequences which code for the oxyR gene
AU2002212114A1 (en) * 2000-08-26 2002-03-13 Degussa A.G. Nucleotide sequences which code for the ccpa1 gene
EP1313758A1 (de) * 2000-08-26 2003-05-28 Degussa AG Nukleotidsequenzen die das oxyr gen kodieren
US6838267B2 (en) 2000-08-26 2005-01-04 Degussa Ag Nucleotide sequences coding for the ccpA1 gene
EP1313856B1 (de) * 2000-08-31 2007-03-21 Degussa GmbH Citb gen aus corynebakterien und seine verwendung zur herstellung von l-aminosäuren
US6825030B2 (en) * 2000-08-31 2004-11-30 Degussa Ag Nucleotide sequences encoding a sensor kinase, citA, from corynebacterium glutamicum
DE10109690A1 (de) * 2000-09-02 2002-03-14 Degussa Neue für das metY-Gen kodierende Nukleotidsequenzen
EP1320616A2 (de) * 2000-09-02 2003-06-25 Degussa AG Gensequenzen für sige von corynebacterium glutamicum
AU2001293740A1 (en) 2000-09-02 2002-03-13 Degussa A.G. Nucleotide sequence coding for the sigc gene of corynebacterium glutamicum
WO2002018599A1 (en) * 2000-09-02 2002-03-07 Degussa Ag Nucleotide sequences coding for the sigm gene
DE10043331A1 (de) * 2000-09-02 2002-03-14 Degussa Neue für das sigD-Gen kodierende Nukleotidsequenzen
AU8198401A (en) * 2000-09-02 2002-03-13 Degussa Nucleotide sequences which code for the metr and metz genes
US6812016B2 (en) 2000-09-02 2004-11-02 Degussa Ag Nucleotide sequences which code for the metY gene
US6815196B2 (en) * 2000-09-02 2004-11-09 Degussa Ag Nucleotide sequences encoding o-succinylhomoserine sulfhydrylase
WO2002018598A1 (en) * 2000-09-02 2002-03-07 Degussa Ag Nucleotide sequences which code for the sigh gene
US6913908B2 (en) * 2000-09-02 2005-07-05 Degussa Ag Methods of making L-amino acids in coryneform using the sigE gene
US6822085B2 (en) 2000-09-03 2004-11-23 Degussa Ag Nucleotide sequences which code for the cysD, cysN, cysK, cysE and cysH genes
DE10136986A1 (de) * 2000-09-03 2002-03-21 Degussa Für Gene cysD, cysN, cysK, cysE und cysH kodierende Nukleotidsequenzen
WO2002022843A2 (en) * 2000-09-09 2002-03-21 Degussa Ag Nucleotide sequences which code for the dep34 gene
US6746854B2 (en) * 2000-09-09 2004-06-08 Degussa Ag Nucleotide sequences encoding histidine kinase from corynebacterium glutamicum
DE10044681A1 (de) * 2000-09-09 2002-03-21 Degussa Neue für das lldD2-Gen kodierende Nukleotidsequenzen
AU2001293723A1 (en) * 2000-09-09 2002-03-22 Degussa A.G. Nucleotide sequences coding for the dep33 gene
AU2001279804A1 (en) * 2000-09-09 2002-03-22 Degussa A.G. Nucleotide sequences coding for the hisc2 gene
ATE329927T1 (de) * 2000-09-09 2006-07-15 Degussa Rekombinante coryneformbakterie die glyceraldehyde-3-phosphate dehydrogenase -2 überexprimieren , und verfahren zur herstellung von l-lysine
US6759224B2 (en) 2000-09-09 2004-07-06 Degussa Ag Nucleotide sequences which code for the sahH gene
EP1315744A1 (de) * 2000-09-09 2003-06-04 Degussa AG Nukleotidsequenzen, die das clpc gen kodieren
AU2001279755A1 (en) * 2000-09-09 2002-03-22 Degussa A.G. Nucleotide sequences which code for the sahh gene
WO2002020572A2 (en) * 2000-09-09 2002-03-14 Degussa Ag Nucleotide sequences coding for the chrs gene
AU2001295470A1 (en) * 2000-09-09 2002-03-22 Degussa A.G. Nucleotide sequences which code for the gpmb gene
US20020155554A1 (en) * 2000-09-09 2002-10-24 Brigitte Bathe Nucleotide sequences which code for the chrA gene
AU2001295456A1 (en) * 2000-09-12 2002-03-26 Degussa A.G. Nucleotide sequences which code for the gora gene
AU2001295539A1 (en) * 2000-09-12 2002-03-26 Degussa A.G. Nucleotide sequences coding for the pknd gene
AU2001282132A1 (en) * 2000-09-12 2002-03-26 Degussa A.G. Isolation and sequencing of the pknb gene of c. glutamicum
US6939692B2 (en) 2000-09-12 2005-09-06 Degussa Ag Nucleotide sequences coding for the pknB gene
WO2002022670A1 (en) * 2000-09-12 2002-03-21 Degussa Ag Nucleotide sequences coding for the ftsx gene
AU2001285878A1 (en) 2000-09-12 2002-03-26 Degussa A.G. Nucleotide sequences which code for the roda gene
US6927052B2 (en) 2000-09-12 2005-08-09 Degussa Ag Nucleotide sequences coding for the pknD gene
DE10045497A1 (de) * 2000-09-13 2002-03-28 Degussa Neue für das ppsA-Gen kodierende Nukleotidsequenzen
DE10045496A1 (de) 2000-09-14 2002-03-28 Degussa Neue für das ptsi-Gen kodierende Nukleotidsequenzen
DE10045486A1 (de) * 2000-09-14 2002-04-11 Degussa Neue für das pstC2-Gen kodierende Nukleotidsequenzen
WO2002022669A1 (en) * 2000-09-14 2002-03-21 Degussa Ag Nucleotide sequences coding for the suga gene
DE10045487A1 (de) * 2000-09-14 2002-04-11 Degussa Neue für das ccsB-Gen kodierende Nukleotidsequenzen
AU2001278509A1 (en) * 2000-09-15 2002-03-26 Degussa A.G. Nucleotide sequences which code for the atr43 gene
DE10045579A1 (de) * 2000-09-15 2002-04-11 Degussa Neue für das atr61-Gen kodierende Nukleotidsequenzen
US20020106750A1 (en) * 2000-09-19 2002-08-08 Mike Farwick Nucleotide sequences which code for the def gene
EP1319077B1 (de) * 2000-09-19 2005-08-31 Degussa AG Nukleinsäuren kodierend für das tmk gen
US20020098554A1 (en) * 2000-09-19 2002-07-25 Mike Farwick Nucleotide sequences coding for the pepC gene
DE10046625A1 (de) * 2000-09-20 2002-04-11 Degussa Neue für das ndkA-Gen kodierende Nukleotidsequenzen
DE10046623A1 (de) * 2000-09-20 2002-03-28 Degussa Neue für das dps-Gen kodierende Nukleotidsequenzen
EP1319076A1 (de) * 2000-09-20 2003-06-18 Degussa AG Nukleotidsequenz, die für das thya-gen kodiert
US6946271B2 (en) * 2000-09-20 2005-09-20 Degussa Ag Nucleotide sequences which code for the menE gene
DE10047404A1 (de) * 2000-09-26 2002-04-11 Degussa Neue für das msik-Gen kodierende Nukleotidsequenzen
DE10047403A1 (de) * 2000-09-26 2002-04-11 Degussa Neue für das ppgK-Gen kodierende Nukleotidsequenzen
EP1320610A1 (de) * 2000-09-27 2003-06-25 Degussa AG Für das cobw-gen kodierende nukleotidsequenzen
US7026158B2 (en) * 2000-09-27 2006-04-11 Degussa Ag Nucleotide sequences which code for the mikE17 gene
DE10047864A1 (de) * 2000-09-27 2002-04-11 Degussa Neue für das truB-Gen kodierende Nukleotidsequenzen
DE10047865A1 (de) * 2000-09-27 2002-04-18 Degussa Neue für das deaD-Gen kodierende Nukleotidsequenzen
DE10047866A1 (de) * 2000-09-27 2002-04-11 Degussa Neue für das dep67-Gen kodierende Nukleotidsequenzen
WO2002034775A2 (en) * 2000-10-28 2002-05-02 Degussa Ag Nucleotide sequences encoding the hemd and hemb genes
US20020168732A1 (en) * 2000-11-10 2002-11-14 Bettina Moeckel Process for the fermentative preparation of L-amino acids using coryneform bacteria
DE10055870A1 (de) * 2000-11-10 2002-05-29 Degussa Neue für das nadC-Gen kodierende Nukleotidsequenzen
WO2002038598A1 (en) * 2000-11-10 2002-05-16 Degussa Ag Nucleotide sequences which code for the nada gene
DE10055869A1 (de) 2000-11-10 2002-05-29 Degussa Neue für das nadA-Gen kodierende Nukleotidsequenzen
US7141388B2 (en) 2000-11-15 2006-11-28 Archer-Daniels-Midland Company Nucleotide sequences for transcriptional regulation in corynebacterium glutamicum
DE10057801A1 (de) * 2000-11-22 2002-05-23 Degussa Neue für das cysQ-Gen kodierende Nukleotidsequenzen
AU2002223637A1 (en) 2000-11-22 2002-06-03 Degussa A.G. Nucleotide sequences which code for the mtra and mtrb gene
DE10063314A1 (de) * 2000-12-20 2002-07-04 Degussa Neue für das ilvE-Gen kodierende Nukleotidsequenzen
CN100334213C (zh) * 2000-12-22 2007-08-29 巴斯福股份公司 棒状杆菌基因
WO2002059329A1 (de) * 2001-01-25 2002-08-01 Degussa Ag Neue für das cite-gen kodierende nukleotidsequenzen
EP1358337A1 (de) * 2001-01-30 2003-11-05 Degussa AG Das otsa gen von corynebacterium glutamicum
AU2002247644A1 (en) * 2001-02-16 2002-09-04 Degussa Ag Nucleotide sequences of the ribosomal protein s12 gene (rpsl) from corynebacterium glutamicum
US6783967B2 (en) 2001-02-16 2004-08-31 Degussa Ag Nucleotide sequences which code for the rpoB gene
EP1239040A3 (de) * 2001-02-16 2003-01-08 Degussa AG Mutationen im rpoB-Gen L-Lysin produzierender Corynebacterium glutamicum-Stämme und Verfahren zur Herstellung von L-Lysin
DE10112992A1 (de) 2001-03-17 2002-09-26 Degussa Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
DE10126164A1 (de) * 2001-05-30 2002-12-05 Degussa Für das metD-gen kodierende Nukleotidsequenzen
US20030113879A1 (en) 2001-06-06 2003-06-19 Mike Farwick Novel nucleotide sequences coding the citE gene
DE10128510A1 (de) * 2001-06-13 2002-12-19 Degussa Methode zur Fermentationskontrolle
EP1411116B1 (de) 2001-07-26 2008-04-23 Ajinomoto Co., Inc. Peptidsynthasegen, peptidsynthase und verfahren zur herstellung eines dipeptids
CA2456416A1 (en) * 2001-08-06 2003-02-20 Degussa Ag Coryneform bacteria which produce chemical compounds ii
US7160711B2 (en) 2001-08-06 2007-01-09 Degussa Ag Coryneform bacteria which produce chemical compounds I
CA2455878A1 (en) * 2001-08-06 2003-05-15 Degussa Ag Production of l-lysine by genetically modified corynebacterium glutamicum strains
US20030092139A1 (en) * 2001-08-09 2003-05-15 Degussa Ag Process for the fermentative preparation of L-amino acids using coryneform bacteria
DE10154292A1 (de) * 2001-11-05 2003-05-15 Basf Ag Gene die für Stoffwechselweg-Proteine codieren
DE10154177A1 (de) * 2001-11-05 2003-05-08 Basf Ag Gene die für neue Proteine codieren
DE10154181A1 (de) * 2001-11-05 2003-05-15 Basf Ag Gene die für Stressresistenz-und Toleranz-Proteine codieren
DE10154175A1 (de) * 2001-11-05 2003-05-15 Basf Ag Gene die für Homeostase-und Adaptions-Proteine codieren
DE10154245A1 (de) * 2001-11-05 2003-06-05 Basf Ag Gene die für regulatorische Proteine codieren
DE10154270A1 (de) * 2001-11-05 2003-05-15 Basf Ag Gene die für Kohlenstoffmetabolismus- und Energieproduktion-Proteine codieren
DE10154246A1 (de) * 2001-11-05 2003-05-08 Basf Ag Gene die für DNA-Replikations-und Pathogenese-Proteine codieren
DE10154180A1 (de) * 2001-11-05 2003-05-15 Basf Ag gene die für genetische Stabilitäts-, genexpressions-und Faltungsproteine codieren
DE10155505A1 (de) 2001-11-13 2003-05-22 Basf Ag Gene die für Glucose-6-Phosphat-Dehydrogenase Proteine codieren
ATE423843T1 (de) 2001-12-03 2009-03-15 Kyowa Hakko Kogyo Kk Mutierte 6-phosphogluconat-dehydrogenase
DE10162730A1 (de) * 2001-12-20 2003-07-03 Degussa Allele des glk-Gens aus coryneformen Bakterien
DE10162729A1 (de) * 2001-12-20 2003-07-03 Degussa Allele des sigA-Gens aus coryneformen Bakterien
DE10163167A1 (de) * 2001-12-21 2003-07-03 Degussa Verfahren zur fermentativen Herstellung von L-Aminosäuren und Verwendung coryneformer Bakterien
AUPR977601A0 (en) * 2001-12-28 2002-01-31 Delta Biotechnology Limited Defective entities and uses therefor
DE10210527A1 (de) 2002-03-09 2003-09-18 Degussa Allele des aceA-Gens aus coryneformen Bakterien
ATE474918T1 (de) 2002-03-19 2010-08-15 Kyowa Hakko Bio Co Ltd Mutierte isopropylmalatisomerase
DE10217058A1 (de) 2002-04-17 2003-11-27 Basf Ag Verfahren zur Herstellung von schwefelhaltigen Feinchemikalien
EP1362866A1 (de) 2002-05-16 2003-11-19 Basf Aktiengesellschaft Verwendung des glxR-Repressores zur Lysin-Synthese in Corynebacterium glutamicum
DE10222858A1 (de) 2002-05-23 2003-12-04 Basf Ag Verfahren zur fermentativen Herstellung schwefelhaltiger Feinchemikalien
DE10232776A1 (de) * 2002-07-18 2004-04-08 Henkel Kgaa Oligonukleotide zum Nachweis von Mikroorganismen
DE10239073A1 (de) 2002-08-26 2004-03-11 Basf Ag Verfahren zur fermentativen Herstellung schwefelhaltiger Feinchemikalien
DE10239082A1 (de) 2002-08-26 2004-03-04 Basf Ag Verfahren zur fermentativen Herstellung schwefelhaltiger Feinchemikalien
DE10239308A1 (de) 2002-08-27 2004-03-11 Basf Ag Verfahren zur fermentativen Herstellung von schwefelhaltigen Feinchemikalien
DE10254074A1 (de) * 2002-11-19 2004-06-17 Forschungszentrum Jülich GmbH Verfahren zur mikrobiellen Herstellung von Stoffwechselprodukten
JP2004166592A (ja) * 2002-11-20 2004-06-17 Ajinomoto Co Inc メチロトローフを用いたｌ−アミノ酸の製造法
JP2004187684A (ja) * 2002-11-26 2004-07-08 Ajinomoto Co Inc Ｌ−グルタミンの製造法及びｌ−グルタミン生産菌
DE60335774D1 (de) 2002-11-26 2011-03-03 Ajinomoto Kk Methode für die Produktion von L-Glutamin und L-Glutamin-produzierendes Bakterium
JP2006521083A (ja) * 2002-11-29 2006-09-21 ビーエーエスエフ　アクチェンゲゼルシャフト メチオニンの生産方法
DE10261579A1 (de) 2002-12-23 2004-07-15 Basf Ag Verfahren zur Herstellung von Trehalose-freien Aminosäuren
KR100969177B1 (ko) * 2003-03-04 2010-07-08 산토리 홀딩스 가부시키가이샤 양조 효모 유전자의 스크리닝 방법
DE10311399A1 (de) * 2003-03-13 2004-09-23 Forschungszentrum Jülich GmbH Nukleotidsequenzen coryneformer Bakterien codierend für am L-Serinstoffwechsel beteiligte Proteine sowie Verfahren zur mikrobiellen Herstellung von L-Serin
US7468262B2 (en) * 2003-05-16 2008-12-23 Ajinomoto Co., Inc. Polynucleotides encoding useful polypeptides in corynebacterium glutamicum ssp. lactofermentum
CN100558244C (zh) * 2003-05-27 2009-11-11 味之素株式会社 饮食品的口味和/或风味的改善方法
EP1491634A1 (de) * 2003-06-26 2004-12-29 Degussa AG Feedback resistente Acetohydroxysäure-Synthetase Mutanten
JP4469568B2 (ja) 2003-07-09 2010-05-26 三菱化学株式会社 有機酸の製造方法
CN100575496C (zh) 2003-08-28 2009-12-30 三菱化学株式会社 产生琥珀酸的方法
CN1852978A (zh) 2003-09-17 2006-10-25 三菱化学株式会社 制备无－氨基有机酸的方法
DE10344739A1 (de) * 2003-09-26 2005-04-14 Degussa Ag Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
WO2005030973A1 (ja) * 2003-09-30 2005-04-07 Ajinomoto Co., Inc. 発酵液からのコハク酸の精製方法
KR20050056668A (ko) * 2003-12-10 2005-06-16 씨제이 주식회사 코리네박테리움의 신규 ｌ-스레오닌 유입유전자 및 상기유전자를 이용한 ｌ-스레오닌 생산균주 개발방법
DE10359595A1 (de) * 2003-12-18 2005-07-28 Basf Ag Pgro-Expressionseinheiten
DE10359661A1 (de) 2003-12-18 2005-07-28 Basf Ag Genvarianten die für Proteine aus dem Stoffwechselweg von Feinchemikalien codieren
DE10359668A1 (de) 2003-12-18 2005-07-14 Basf Ag Verfahren zur Herstellung von Methionin
US8728795B2 (en) 2003-12-18 2014-05-20 Basf Se Pgro expression units
DE10359594A1 (de) * 2003-12-18 2005-07-28 Basf Ag PEF-TU-Expressionseinheiten
AU2004299729A1 (en) * 2003-12-18 2005-06-30 Basf Aktiengesellschaft Methods for the preparation of lysine by fermentation of corynebacterium glutamicum
DE10359660A1 (de) * 2003-12-18 2005-07-28 Basf Ag Psod-Expressionseinheiten
DE102004009453A1 (de) * 2004-02-27 2005-09-15 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von coryneformen Bakterien
JP4780783B2 (ja) * 2004-02-27 2011-09-28 協和発酵バイオ株式会社 アミノ酸の製造法
DE102004009454A1 (de) * 2004-02-27 2005-09-15 Degussa Ag Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von rekombinanten Mikroorganismen
DE102004013503A1 (de) 2004-03-18 2005-10-06 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
WO2005111206A1 (en) * 2004-05-18 2005-11-24 Kao Corporation Maltose-1-phosphate producing enzyme
JP5572279B2 (ja) * 2004-05-20 2014-08-13 味の素株式会社 コハク酸生産菌及びコハク酸の製造方法
BRPI0510919A (pt) 2004-05-20 2008-05-20 Ajinomoto Kk bactéria produtora de ácido succìnico e processo para produzir ácido succìnico
DE102004035067A1 (de) * 2004-07-20 2006-02-16 Basf Ag P1-35-Expressionseinheiten
DE102004035074A1 (de) * 2004-07-20 2006-02-16 Basf Ag P1-34-Expressionseinheiten
DE102004035065A1 (de) 2004-07-20 2006-02-16 Basf Ag P-ET-TS-Expressionseinheiten
DE102004035052A1 (de) 2004-07-20 2006-02-16 Basf Ag Mikroorganismen zur Herstellung von schwefelhaltigen Verbindungen
JP4595506B2 (ja) 2004-11-25 2010-12-08 味の素株式会社 Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造方法
DE102004061846A1 (de) * 2004-12-22 2006-07-13 Basf Ag Mehrfachpromotoren
US7794989B2 (en) 2004-12-28 2010-09-14 Ajinomoto Co., Inc. L-glutamic acid-producing microorganism and a method for producing L-glutamic acid
BR122019024048B1 (pt) * 2004-12-28 2022-05-24 Ajinomoto Co., Inc Método para produzir ácido l-glutâmico
KR100653742B1 (ko) * 2004-12-30 2006-12-05 씨제이 주식회사 신규한 ｌ-라이신-유도성 프로모터
DE102005032429A1 (de) 2005-01-19 2006-07-20 Degussa Ag Allele des mqo-Gens aus coryneformen Bakterien
US20070092951A1 (en) 2005-03-24 2007-04-26 Degussa Ag Alleles of the zwf gene from coryneform bacteria
DE102005013676A1 (de) 2005-03-24 2006-09-28 Degussa Ag Allele des zwf-Gens aus coryneformen Bakterien
DE102005023829A1 (de) 2005-05-24 2006-11-30 Degussa Ag Allele des opcA-Gens aus coryneformen Bakterien
KR100906263B1 (ko) * 2005-05-27 2009-07-06 에보니크 데구사 게엠베하 메티오닌의 생산 방법
WO2007017954A1 (en) * 2005-08-05 2007-02-15 Kao Corporation Maltose-1-phosphate-producing enzyme
CN101248170B (zh) * 2005-08-26 2011-01-26 味之素株式会社 产生l-谷氨酸的细菌和用于产生l-谷氨酸的方法
DE102005043979A1 (de) * 2005-09-15 2007-03-22 Forschungszentrum Jülich GmbH Verfahren zur Produktion von Aminosäuren in aminosäureproduzierenden Mikroorganismen
DE102005047596A1 (de) 2005-10-05 2007-04-12 Degussa Ag Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
JP5088136B2 (ja) 2005-10-18 2012-12-05 味の素株式会社 コハク酸の製造方法
KR100789270B1 (ko) * 2005-11-30 2008-01-02 씨제이 주식회사 Ｌ-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용하여 ｌ-라이신을 생산하는 방법
KR100789271B1 (ko) 2005-11-30 2008-01-02 씨제이 주식회사 Ｌ-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용하여 ｌ-라이신을 생산하는 방법
JP2007185184A (ja) * 2005-12-16 2007-07-26 Ajinomoto Co Inc Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造法
US8067211B2 (en) 2005-12-27 2011-11-29 Kyowa Hakko Bio Co., Ltd. Method for production of L-glutamine
CN101389752B (zh) 2006-02-24 2015-08-05 三菱化学株式会社 能够产生有机酸的细菌以及产生有机酸的方法
CN101400799A (zh) * 2006-03-09 2009-04-01 巴斯夫欧洲公司 生产β-赖氨酸的方法
CN102732578B (zh) * 2006-03-30 2016-02-17 巴斯夫欧洲公司 生产尸胺的方法
DE102006026328A1 (de) * 2006-06-02 2008-01-03 Evonik Degussa Gmbh Verfahren zur Herstellung eines L-Lysin enthaltenden Futtermitteladditivs
DE102006032634A1 (de) 2006-07-13 2008-01-17 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren
EP2612915B1 (de) 2006-09-01 2015-04-08 Kyowa Hakko Bio Co., Ltd. Verfahren zur Herstellung von L-Glutamin
JP5034395B2 (ja) * 2006-09-13 2012-09-26 三菱化学株式会社 有機酸生産菌及び有機酸の製造方法
EP2081964A4 (de) 2006-10-12 2012-07-11 Univ Johns Hopkins Alginat- und alginatlyase-zusammensetzungen und verwendungsverfahren
DE102006050489A1 (de) 2006-10-26 2008-04-30 Evonik Degussa Gmbh Allele des prpD1-Gens aus coryneformen Bakterien
WO2008063650A2 (en) * 2006-11-20 2008-05-29 President And Fellows Of Harvard College Systems of hydrogen and formic acid production in yeast
KR100822041B1 (ko) * 2006-12-21 2008-04-15 씨제이제일제당 (주) 몰리브덴 보조인자 생합성 효소 에이 코딩 유전자의 발현이강화된 코리네박테리움 속 미생물 및 이를 이용한엘-라이신 생산방법
KR100838035B1 (ko) * 2006-12-29 2008-06-12 씨제이제일제당 (주) Ｌ-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용한 ｌ-라이신 생산 방법
KR100838038B1 (ko) 2006-12-29 2008-06-12 씨제이제일제당 (주) Ｌ-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용한 ｌ-라이신 생산 방법
KR100789274B1 (ko) * 2007-01-15 2008-01-02 씨제이 주식회사 코리네박테리움 글루타미쿰에서 유래한 신규한 프로모터핵산 분자, 그 프로모터를 포함하는 재조합 벡터, 그재조합 벡터를 포함하는 숙주 세포 및 그 숙주 세포를이용하여 유전자를 발현하는 방법
KR100830826B1 (ko) * 2007-01-24 2008-05-19 씨제이제일제당 (주) 코리네박테리아를 이용하여 글리세롤을 포함한탄소원으로부터 발효산물을 생산하는 방법
DE102007005072A1 (de) 2007-02-01 2008-08-07 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von Cadaverin
KR100860932B1 (ko) * 2007-02-08 2008-09-29 씨제이제일제당 (주) 신규한 프로모터 및 이의 용도
DE102007051024A1 (de) 2007-03-05 2008-09-11 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
WO2008126896A1 (ja) * 2007-04-10 2008-10-23 Ajinomoto Co., Inc. 有機酸の製造方法
CN101849017A (zh) * 2007-06-15 2010-09-29 赢创德固赛有限责任公司 具有下调的维生素b12系统的微生物
BRPI0818162B1 (pt) 2007-10-10 2023-11-07 Givaudan Sa Método para identificar modulador da formação de mau cheiro no corpo, kit, método para inibir peptidase em sua capacidade de clivar seu substrato e método para formar peptidase
KR100987281B1 (ko) 2008-01-31 2010-10-12 씨제이제일제당 (주) 개량된 프로모터 및 이를 이용한 ｌ-라이신의 생산 방법
US8771998B2 (en) 2008-02-21 2014-07-08 Basf Se Process for the production of gamma-aminobutyric acid
US8932861B2 (en) 2008-04-10 2015-01-13 Cj Cheiljedang Corporation Transformation vector comprising transposon, microorganisms transformed with the vector, and method for producing L-lysine using the microorganism
KR101126041B1 (ko) * 2008-04-10 2012-03-19 씨제이제일제당 (주) 트랜스포존을 이용한 형질전환용 벡터, 상기 벡터로형질전환된 미생물 및 이를 이용한 ｌ-라이신 생산방법
DE102008001874A1 (de) 2008-05-20 2009-11-26 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren
UA112050C2 (uk) * 2008-08-04 2016-07-25 БАЄР ХЕЛСКЕР ЛЛСі Терапевтична композиція, що містить моноклональне антитіло проти інгібітора шляху тканинного фактора (tfpi)
DE102008044768A1 (de) 2008-08-28 2010-03-04 Evonik Degussa Gmbh Verfahren zur Herstellung von organisch-chemischen Verbindungen unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
US8530203B2 (en) * 2008-09-01 2013-09-10 Shinshu University Process for producing useful substance
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
JPWO2010095642A1 (ja) 2009-02-18 2012-08-23 国立大学法人信州大学 有用物質の製造方法
US8637295B1 (en) 2009-02-20 2014-01-28 Evonik Degussa Gmbh Process for the production of L-lysine
DE102009030342A1 (de) 2009-06-25 2010-12-30 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von organisch chemischen Verbindungen
US20120117867A1 (en) * 2009-07-23 2012-05-17 Basf Plant Science Company Gmbh Plants with Increased Yield
JP5663859B2 (ja) * 2009-11-13 2015-02-04 三菱化学株式会社 非アミノ有機酸生産菌および非アミノ有機酸の製造方法
CN102753682A (zh) 2009-12-17 2012-10-24 巴斯夫欧洲公司 用于生产尸胺的方法和重组微生物
KR101174267B1 (ko) * 2010-01-06 2012-08-14 씨제이제일제당 (주) Ｌ-오르니틴 또는 ｌ-아르기닌 생산 변이주 및 이의 제조방법
BR112012021070B1 (pt) * 2010-02-23 2020-02-27 Toray Industries Inc. Método para produzir cadaverina
KR101134700B1 (ko) 2010-02-24 2012-04-13 씨제이제일제당 (주) 코리네형 세포의 정지기에 분비되는 자가유도체에 의해 조절받는 뉴클레오티드 및 이를 이용한 스크리닝 방법
PT3345615T (pt) 2010-03-01 2020-01-17 Bayer Healthcare Llc Anticorpos monoclonais otimizados contra inibidor da via do fator tecidual (tfpi)
DE102010003419B4 (de) 2010-03-30 2019-09-12 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von L-Ornithin
KR101269810B1 (ko) 2010-07-15 2013-05-30 씨제이제일제당 (주) Ｌ－라이신 생산능이 향상된 미생물 및 이를 이용한 ｌ－라이신 생산방법
EP2430152B1 (de) * 2010-07-15 2016-08-24 CJ CheilJedang Corporation Mikroorganismus mit verstärkter l-lysin-produktivität und verfahren zur l-lysin-herstellung damit
EP2639295B1 (de) * 2010-11-10 2017-06-28 Green Phenol Development Co., Ltd. Mittel zur transformierung coryneformer bakterien sowie verfahren zur phenolherstellung damit
WO2012083363A1 (en) 2010-12-22 2012-06-28 Murdoch Childrens Research Institute A method of treatment
US9745608B2 (en) 2011-02-22 2017-08-29 Basf Se Processes and recombinant microorganisms for the production of cadaverine
DE102011006716A1 (de) 2011-04-04 2012-10-04 Evonik Degussa Gmbh Mikroorganismus und Verfahren zur fermentativen Herstellung einer organisch-chemischen Verbindung
RU2496867C2 (ru) * 2011-04-25 2013-10-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Способ получения l-аминокислоты семейства глутамата с использованием коринеформной бактерии
EP2711013A4 (de) * 2011-05-18 2015-03-04 Ajinomoto Kk Immunstimulans für tiere, futter damit und herstellungsverfahren dafür
DE102011118019A1 (de) 2011-06-28 2013-01-03 Evonik Degussa Gmbh Varianten des Promotors des für die Glyzerinaldehyd-3-phosphat-Dehydrogenase kodierenden gap-Gens
US10703784B2 (en) * 2011-09-30 2020-07-07 La Jolla Institute For Allergy And Immunology Antigens and epitopes derived from Mycobacterium tuberculosis
US9644220B2 (en) 2011-12-22 2017-05-09 Basf Se Processes and recombinant microorganisms for the production of fine chemicals
CN102604881B (zh) * 2012-03-31 2013-12-18 福建省麦丹生物集团有限公司 生产l-异亮氨酸的工程菌及其应用
US9347048B2 (en) 2012-04-27 2016-05-24 Evonik Technochemie Gmbh Feedback-resistant alpha-isopropylmalate synthases
WO2014004753A1 (en) * 2012-06-29 2014-01-03 Archer Daniels Midland Company Betaine enhancement of fermentation to make c4 diacids
KR20140014648A (ko) 2012-07-25 2014-02-06 삼성전자주식회사 1,4-부탄디올의 고효율 생산을 위한 변형 미생물
DE102012016716A1 (de) 2012-08-22 2014-02-27 Forschungszentrum Jülich GmbH Verfahren zur Herstellung von Vektoren enthaltend ein für in seiner feedback-Inhibierung gemindertes oder ausgeschaltetes Enzym kodierendes Gen und deren Verwendung für die Herstellung von Aminosäuren und Nukleotiden
EP2762571A1 (de) 2013-01-30 2014-08-06 Evonik Industries AG Mikroorganismus und Verfahren zur fermentativen Herstellung von Aminosäuren
KR20140102393A (ko) 2013-02-13 2014-08-22 씨제이제일제당 (주) L-쓰레오닌 생산능을 가지는 재조합 에스케리키아 속 미생물 및 이를 이용한 l-쓰레오닌의 생산방법
KR101607741B1 (ko) 2013-03-20 2016-03-31 씨제이제일제당 (주) 퓨트레신 생산 재조합 미생물 및 이를 이용한 퓨트레신 생산방법
EP2868745B1 (de) 2013-05-13 2017-06-21 Ajinomoto Co., Inc. Verfahren zur Herstellung einer L-Aminosäure
KR20140140215A (ko) * 2013-05-28 2014-12-09 경상대학교산학협력단 사이코스 3-에피머라제 효소를 코딩하는 폴리뉴클레오티드를 포함하는 코리네박테리움 및 이를 이용한 사이코스의 생산 방법
ES2623161T3 (es) 2013-06-03 2017-07-10 Evonik Degussa Gmbh Procedimiento para la preparación de L-valina utilizando corinebacterias recombinantes que contienen el operón ilvBN inducible por propionato
EP2818551B1 (de) * 2013-06-28 2017-04-05 Samsung Electronics Co., Ltd Corynebakterium, in dem die für Koenzym A unabhängige Succinat-Semialdehyddehydrogenease und L-Laktat Dehydrogenase kodierenden Gene attenuiert sind und ein Verfahren zur Herstellung von C4-Verbindungen, z.B. 4-Hydroxybutyrat
US20150031101A1 (en) * 2013-07-26 2015-01-29 Samsung Electronics Co., Ltd. Bacterial cell having enhanced succinic acid production and a method for producing the succinic acid using the same
KR101582008B1 (ko) * 2013-10-15 2015-12-31 씨제이제일제당 (주) 생물막 형성 억제 활성을 가지는 유전자 및 이 유전자가 불활성화된 균주를 이용한 l-라이신 생산 방법
KR101498630B1 (ko) * 2013-10-28 2015-03-04 씨제이제일제당 주식회사 Ｌ-라이신 생산능이 향상된 코리네박테리움 속 미생물 및 이를 이용한 l-라이신 생산방법
US20150125919A1 (en) * 2013-11-05 2015-05-07 Samsung Electronics Co., Ltd. Microorganism with increased iron-regulated abc transporter activity and method of producing hydroxycarboxylic acid by using the microorganism
CN103698530B (zh) * 2013-11-25 2015-08-19 广东体必康生物科技有限公司 结核分支杆菌蛋白在制备诊断活动性肺结核的产品中的用途
KR101565770B1 (ko) * 2013-12-13 2015-11-04 씨제이제일제당 주식회사 L-라이신 생산능이 향상된 코리네박테리움 속 미생물 및 이를 이용한 l-라이신을 생산하는 방법
KR101689451B1 (ko) * 2014-02-12 2017-01-02 씨제이제일제당 (주) L-쓰레오닌 생산능을 가지는 재조합 에스케리키아 속 미생물 및 이를 이용한 l-쓰레오닌의 생산방법
CN104845923B (zh) * 2014-02-14 2018-03-23 中国科学院微生物研究所 生产l‑组氨酸的方法及其专用重组菌
PL2940143T3 (pl) * 2014-04-30 2020-06-29 Evonik Operations Gmbh Sposób wytwarzania L-aminokwasów z użyciem bakterii bazofilowych
EP2940144A1 (de) 2014-04-30 2015-11-04 Evonik Degussa GmbH Verfahren zur Produktion von L-Lysin unter Verwendung eines alkaliphilen Bakteriums
CN106574254A (zh) * 2014-04-30 2017-04-19 赢创德固赛有限公司 使用嗜碱性细菌生产l‑氨基酸的方法
KR101530819B1 (ko) * 2014-05-08 2015-06-22 씨제이제일제당 (주) L-라이신 생산능이 향상된 미생물 및 이를 이용한 l-라이신 생산방법
KR101539370B1 (ko) * 2014-05-14 2015-07-24 씨제이제일제당 주식회사 L-라이신을 생산하는 코리네박테리움 속 미생물 및 이를 이용한 l-라이신의 생산방법
KR101720836B1 (ko) 2014-08-05 2017-04-03 씨제이제일제당 (주) 피드백 저항성 아세토하이드록시산 신타아제 변이체 및 이를 이용한 l-발린의 생산방법
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
EP3265108A4 (de) 2015-03-04 2019-03-13 Ariel-University Research and Development Company Ltd. Peptide und zusammensetzungen damit sowie verwendungen davon bei der behandlung von krankheiten
KR101640711B1 (ko) 2015-04-20 2016-07-19 씨제이제일제당 (주) 글루코네이트 리프레서 변이체, 이를 포함하는 l-라이신을 생산하는 미생물 및 이를 이용한 ｌ－라이신 생산방법
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
KR101766964B1 (ko) * 2015-08-27 2017-08-09 씨제이제일제당 (주) L-라이신 생산능을 가지는 코리네박테리움 속 미생물 및 이를 이용한 l-라이신 생산방법
KR101740807B1 (ko) * 2015-08-27 2017-05-26 씨제이제일제당 (주) L-라이신 생산능을 가지는 코리네박테리움 속 미생물 및 이를 이용한 l-라이신 생산방법
KR102771842B1 (ko) * 2015-11-27 2025-02-21 에보닉 오퍼레이션스 게엠베하 L-메티오닌을 제조하는 방법
US9988624B2 (en) 2015-12-07 2018-06-05 Zymergen Inc. Microbial strain improvement by a HTP genomic engineering platform
US11208649B2 (en) 2015-12-07 2021-12-28 Zymergen Inc. HTP genomic engineering platform
BR112018011503A2 (pt) 2015-12-07 2018-12-04 Zymergen Inc promotores da corynebacterium glutamicum
EP3478845A4 (de) 2016-06-30 2019-07-31 Zymergen, Inc. Verfahren zur erzeugung einer glucose-permease-bibliothek und verwendungen davon
US10544390B2 (en) 2016-06-30 2020-01-28 Zymergen Inc. Methods for generating a bacterial hemoglobin library and uses thereof
KR20190027843A (ko) 2016-07-05 2019-03-15 지머젠 인코포레이티드 Rna 데그라도솜 단백질 복합체의 유전자 교란
JP6795211B2 (ja) * 2016-09-15 2020-12-02 Ｎｅｃソリューションイノベータ株式会社 分泌型免疫グロブリンＡ（ｓＩｇＡ）結合核酸分子、ｓＩｇＡ分析用センサ、およびｓＩｇＡの分析方法
US10457963B2 (en) 2016-09-20 2019-10-29 Novogy, Inc. Heterologous production of 10-methylstearic acid
CN106395051B (zh) * 2016-10-19 2018-09-07 石家庄钢铁有限责任公司 一种成捆圆钢端面自动贴标系统中贴标机器人的优选方法
KR101863456B1 (ko) 2016-11-15 2018-06-01 씨제이제일제당 (주) L-라이신을 생산하는 코리네박테리움 속 미생물 및 이를 이용한 l-라이신의 생산방법
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
KR101917480B1 (ko) * 2016-12-29 2018-11-09 씨제이제일제당 (주) Ｌ－라이신을 생산하는 코리네박테리움 속 미생물 및 이를 이용한 ｌ－라이신의 생산방법
CN111521820B (zh) * 2016-12-30 2023-06-16 首都医科大学附属北京胸科医院 结核分枝杆菌蛋白在制备诊断结核潜伏感染者和/或活动性肺结核产品中的用途
CN108314713A (zh) * 2017-01-16 2018-07-24 中国科学院微生物研究所 L-苏氨酸转运蛋白ThrG及其编码基因与应用
DE102017004566A1 (de) * 2017-05-11 2018-11-15 Forschungszentrum Jülich GmbH Pyruvatcarboxylase und für die Pyruvatcarboxylase kodierende DNA, Plasmid enthaltend die DNA, sowie Mikroorganismus zur Produktion und Verfahren zur Herstellung von Produkten, deren Biosynthese Oxalacetat als Vorstufe beinhaltet, Chromosom und Screeningverfahren
KR20200026881A (ko) 2017-06-07 2020-03-11 지머젠 인코포레이티드 코리네박테리움 글루타미컴으로부터의 프로모터 및 보조 유전자 발현을 조절하는 데 이의 용도
WO2019004780A2 (ko) * 2017-06-30 2019-01-03 씨제이제일제당 (주) 신규한 o-숙시닐 호모세린 트랜스퍼라제 변이체 및 이를 이용한 o-숙시닐 호모세린의 제조방법
KR101996129B1 (ko) 2017-07-11 2019-07-04 씨제이제일제당 (주) 아세토하이드록시산 신타아제 변이체, 이를 포함하는 미생물 또는 이를 이용하는 l-분지쇄 아미노산 생산 방법
US11021697B2 (en) 2017-07-11 2021-06-01 Cj Cheiljedang Corporation Acetohydroxy acid synthase variant, microorganism comprising the same, and method of producing L-branched-chain amino acid using the same
EP3456833A1 (de) * 2017-09-18 2019-03-20 Evonik Degussa GmbH Methode zur fermentativen production von l-aminosäuren
EP3467099A1 (de) 2017-10-05 2019-04-10 Evonik Degussa GmbH Verfahren zur fermentativen herstellung von l-aminosäuren
CN109750069B (zh) * 2017-11-01 2025-08-01 宁夏伊品生物科技股份有限公司 生产l-赖氨酸的重组菌、其构建方法以及l-赖氨酸的生产方法
EP3498853A1 (de) 2017-12-14 2019-06-19 Evonik Degussa GmbH Verfahren zur fermentativen herstellung von l-lysin
CN109929887A (zh) * 2017-12-15 2019-06-25 宁夏伊品生物科技股份有限公司 改进的发酵生产l-赖氨酸的方法
KR101999454B1 (ko) 2017-12-19 2019-07-11 씨제이제일제당 (주) L-아르기닌을 생산하는 코리네박테리움 속 미생물 및 이를 이용한 l-아르기닌 생산방법
KR101947945B1 (ko) * 2018-01-25 2019-02-13 씨제이제일제당 (주) L-아미노산을 생산하는 코리네박테리움 속 미생물 및 이를 이용한 l-아미노산의 생산방법
KR102013873B1 (ko) * 2018-01-25 2019-08-23 씨제이제일제당 주식회사 퓨린 뉴클레오티드를 생산하는 코리네박테리움 속 미생물 및 이를 이용한 퓨린 뉴클레오티드의 생산방법
KR101915433B1 (ko) 2018-02-13 2018-11-05 씨제이제일제당 (주) 시트레이트 신타아제 (Citrate synthase)의 활성이 약화된 변이형 폴리펩타이드 및 이를 이용한 L-아미노산 생산방법
WO2019198090A1 (en) 2018-04-13 2019-10-17 Ariel Scientific Innovations Ltd. Treatment of inflammation
KR101947959B1 (ko) 2018-05-28 2019-02-13 씨제이제일제당 (주) 변이형 호모세린 디하이드로게나제 및 이를 이용한 호모세린 또는 호모세린 유래 l-아미노산의 생산 방법
WO2019228937A1 (en) * 2018-05-28 2019-12-05 Universitaet Des Saarlandes Means and methods for the production of glutarate
WO2020011294A1 (de) 2018-07-11 2020-01-16 Forschungszentrum Jülich GmbH D-xylose-dehydrogenase aus coryneformen bakterien und verfahren zur herstellung von d-xylonat
EP3594355A1 (de) 2018-07-12 2020-01-15 Evonik Operations GmbH Verfahren zur fermentativen herstellung von l-lysin
EP3599282B1 (de) 2018-07-24 2021-03-17 Evonik Operations GmbH Verfahren zur fermentativen herstellung von l-lysin
RU2019128538A (ru) 2018-09-26 2021-03-11 Эвоник Оперейшенс ГмбХ Способ ферментативного получения l-лизина
CN115819529B (zh) * 2018-10-19 2025-03-07 中国科学院天津工业生物技术研究所 提高苹果酸产量的新突变蛋白
CN109182556B (zh) * 2018-11-01 2021-11-23 菏泽学院 一种与瓦氏黄颡鱼生长性状相关的snp分子标记及应用
EP3660158A1 (de) 2018-11-29 2020-06-03 Evonik Operations GmbH Verfahren zur fermentativen herstellung von l-lysin
EP3670525A1 (de) 2018-12-18 2020-06-24 Evonik Operations GmbH Verfahren zur fermentativen herstellung von l-lysin unter verwendung von c.-glutamicum-stämmen mit einem mutierten kup-transporter
CN109765379B (zh) * 2018-12-19 2021-11-23 南华大学 结核分枝杆菌蛋白的应用
KR101996769B1 (ko) * 2018-12-21 2019-10-01 씨제이제일제당 (주) 변이형 호모세린 디하이드로게나제 및 이를 이용한 호모세린 또는 호모세린 유래 l-아미노산의 생산 방법
US10829746B2 (en) 2019-01-23 2020-11-10 Evonik Operations Gmbh Method for the fermentative production of L-lysine
CN112410389B (zh) * 2019-08-23 2023-07-18 中国科学院微生物研究所 支链α-酮酸脱氢酶复合体在制备丙二酸单酰辅酶A中的应用
WO2021037190A1 (zh) 2019-08-29 2021-03-04 天津科技大学 一种2-异丙基苹果酸合成酶及其工程菌与应用
CN110540976B (zh) * 2019-08-29 2020-07-24 天津科技大学 一种异丙基苹果酸合成酶及其应用
CN111088202B (zh) * 2019-12-25 2022-01-04 南京工业大学 一种通过生物成膜连续化发酵生产赖氨酸的重组谷氨酸棒杆菌及其构建方法
CN110885364B (zh) * 2019-12-26 2021-02-02 江南大学 一种促进N-乙酰氨基葡萄糖生产的RamA转录因子突变体及其应用
CN110964090B (zh) * 2019-12-26 2021-02-19 江南大学 一种促进n-乙酰氨基葡萄糖生产的蛋白质起始因子if3突变体及其应用
CN112877269B (zh) 2020-01-15 2021-12-24 中国科学院天津工业生物技术研究所 生产赖氨酸的微生物以及赖氨酸的生产方法
CN113121658B (zh) * 2020-01-15 2022-10-21 中国农业大学 根瘤菌中含有sh3结构域的蛋白的基因及其相关生物材料和应用
CN111394374A (zh) * 2020-04-27 2020-07-10 广西大学 一种编码纤维素酶家族GH30的纤维素酶基因gk2691及其应用
KR102360900B1 (ko) * 2020-05-20 2022-02-09 씨제이제일제당 (주) 신규한 폴리펩티드 및 이를 이용한 l-류신의 생산 방법
KR102263091B1 (ko) 2020-05-21 2021-06-09 씨제이제일제당 주식회사 L-분지쇄 아미노산 생산능이 강화된 미생물 및 이를 이용한 l-분지쇄 아미노산 생산방법
KR102311391B1 (ko) * 2020-05-21 2021-10-12 씨제이제일제당 주식회사 L- 분지쇄 아미노산 생산능이 강화된 미생물 및 이를 이용하여 l-분지쇄 아미노산을 생산하는 방법
CN111635454B (zh) * 2020-06-04 2021-12-28 江南大学 利用生物传感器筛选精氨酸高产菌株的方法
CN112266891B (zh) * 2020-10-15 2023-10-31 内蒙古伊品生物科技有限公司 一种产l-氨基酸的重组菌株及其构建方法与应用
BR112022017298A2 (pt) * 2020-06-08 2023-02-07 Heilongjiang Eppen Biotech Co Ltd Microrganismo produtor de l-lisina, sequência polinucleotídica, sequência de aminoácidos, vetores recombinantes, cepas recombinantes, sequência nucleotídica promotora, cassete de expressão e método para produzir l-lisina
KR20230042224A (ko) * 2020-06-08 2023-03-28 이너 몽골리아, 에펜 바이오테크 컴퍼니 리미티드 L-아미노산을 생산하는 재조합 균주 및 이의 구축 방법과 응용
CN111961635B (zh) * 2020-08-07 2023-09-01 内蒙古伊品生物科技有限公司 一种产l-赖氨酸的重组菌株及其构建方法与应用
CN113755492B (zh) * 2020-07-20 2023-05-30 中国科学院天津工业生物技术研究所 丙酮酸羧化酶基因启动子的突变体及其应用
JP7768971B2 (ja) * 2020-08-07 2025-11-12 寧夏伊品生物科技股▲ふん▼有限公司 Ｌ－アミノ酸を生産する組換え菌株、その構築方法及び使用
KR102246288B1 (ko) * 2020-08-13 2021-04-29 씨제이제일제당 주식회사 퓨트레신 생산 미생물 및 이를 이용한 퓨트레신 생산방법
CN112471140A (zh) * 2020-12-22 2021-03-12 华中科技大学 一种细胞株冻存复苏的保护液及制备方法
KR20220092182A (ko) * 2020-12-24 2022-07-01 씨제이제일제당 (주) L-히스티딘 배출 단백질 및 이를 이용한 l-히스티딘 생산 방법
CN112646766B (zh) * 2020-12-30 2023-08-18 内蒙古伊品生物科技有限公司 一种改造基因bbd29_04920的产l-谷氨酸的重组菌株及其构建方法与应用
CN112646767B (zh) * 2020-12-30 2022-08-09 宁夏伊品生物科技股份有限公司 具有增强的l-谷氨酸生产力的菌株及其构建方法与应用
EP4293115A4 (de) * 2021-01-12 2024-12-11 Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences Polynukleotid mit promoteraktivität und verwendung davon bei der herstellung von tragetverbindungen
KR102261851B1 (ko) * 2021-01-15 2021-06-04 씨제이제일제당 (주) 신규한 abc 트랜스포터 atp-결합 단백질 변이체 및 이를 이용한 l-라이신 생산 방법
KR102257841B1 (ko) * 2021-01-15 2021-05-28 씨제이제일제당 주식회사 신규한 피토엔 신타제 변이체 및 이를 이용한 xmp 또는 gmp 생산 방법
KR102281366B1 (ko) * 2021-01-26 2021-07-22 씨제이제일제당 (주) 신규한 테트라하이드로디피콜리네이트 n-숙시닐트랜스퍼라제 변이체 및 이를 이용한 l-발린 생산 방법
EP4060035A4 (de) * 2021-01-27 2023-01-25 CJ CheilJedang Corporation Neuartige ribonuklease-p-variante und verfahren zur herstellung von l-glutaminsäure unter verwendung derselben
KR102281368B1 (ko) * 2021-01-28 2021-07-23 씨제이제일제당 (주) 신규한 단백질 변이체 및 이를 이용한 l-발린 생산 방법
KR102291553B1 (ko) * 2021-01-29 2021-08-18 씨제이제일제당 (주) 신규한 프리모솜 조립 단백질 변이체 및 이를 이용한 l-라이신 생산 방법
KR102344057B1 (ko) * 2021-01-29 2021-12-27 씨제이제일제당 (주) 신규한 단백질 변이체 및 이를 이용한 l-라이신 생산 방법
KR102277034B1 (ko) * 2021-01-29 2021-07-13 씨제이제일제당 (주) 신규한 dahp 신타아제 변이체 및 이를 이용한 l-라이신 생산 방법
KR102258159B1 (ko) * 2021-01-29 2021-05-27 씨제이제일제당 (주) 신규한 말레이트 디하이드로게나제 변이체 및 이를 이용한 l-라이신 생산 방법
EP4092123B1 (de) * 2021-04-07 2025-06-11 CJ CheilJedang Corporation Neuartige transkriptionsreglervariante und verfahren zur herstellung von l-valin unter verwendung derselben
KR102338875B1 (ko) * 2021-04-12 2021-12-10 씨제이제일제당 (주) 신규한 당 인산염 이성질화효소/에피머레이즈 변이체 및 이를 이용한 l-라이신 생산 방법
KR102314884B1 (ko) * 2021-04-12 2021-10-18 씨제이제일제당 (주) 신규한 세포분해 막단백질 변이체 및 이를 이용한 l-라이신 생산 방법
KR102303747B1 (ko) * 2021-04-12 2021-09-16 씨제이제일제당 (주) 신규한 주요 촉진제 수퍼패밀리 퍼미에이즈 변이체 및 이를 이용한 l-라이신 생산 방법
KR102314885B1 (ko) * 2021-04-12 2021-10-18 씨제이제일제당 (주) 신규한 단백질 변이체 및 이를 이용한 l-라이신 생산 방법
WO2022226190A1 (en) * 2021-04-23 2022-10-27 Board Of Trustees Of Michigan State University Synthesis of 3-hydroxypropionic acid via hydration of acetylenecarboxylic acid
KR102339264B1 (ko) * 2021-05-07 2021-12-14 씨제이제일제당 주식회사 신규 프로모터 및 이의 용도
KR102339271B1 (ko) * 2021-05-07 2021-12-14 씨제이제일제당 주식회사 신규 프로모터 및 이의 용도
CN113201524B (zh) * 2021-05-08 2022-09-30 廊坊梅花生物技术开发有限公司 肌醇-3-磷酸合酶突变体及其在构建高产谷氨酰胺的谷氨酸棒杆菌中的应用
WO2022265130A1 (ko) * 2021-06-15 2022-12-22 씨제이제일제당 (주) 신규 프로모터 및 이의 용도
KR102665227B1 (ko) * 2021-06-30 2024-05-10 씨제이제일제당 주식회사 고농도 l-글루탐산을 생산하기 위한 균주 및 이를 이용한 l-글루탐산 생산방법
KR102737642B1 (ko) * 2021-08-27 2024-12-03 씨제이제일제당 주식회사 신규한 초산 대사 조절자 a 변이체 및 이를 이용한 l-분지쇄 아미노산 생산 방법
CN113462583B (zh) * 2021-09-06 2021-12-10 中国科学院天津工业生物技术研究所 生产氨基酸的谷氨酸棒杆菌以及利用该谷氨酸棒杆菌生产氨基酸的方法
WO2023041425A1 (en) 2021-09-20 2023-03-23 Evonik Operations Gmbh Method for the fermentative production of l-lysine using c. glutamicum strains expressing modified gluconate repressor proteins gntr1 and gntr2
WO2023106351A1 (ja) * 2021-12-07 2023-06-15 花王株式会社 芳香族化合物の製造方法
CN114457178B (zh) * 2021-12-07 2023-08-08 浙江省农业科学院 用于预测杨梅果实可溶性固形物的kasp分子标记及其应用
US20250051785A1 (en) * 2021-12-13 2025-02-13 Kao Corporation Novel promoter
CN114315998B (zh) * 2021-12-20 2024-02-06 宁夏伊品生物科技股份有限公司 Cey17_rs00300基因突变体及其在制备l-缬氨酸中的应用
CN114560918B (zh) * 2022-03-14 2024-06-14 宁夏伊品生物科技股份有限公司 Yh66_14275蛋白或其突变体在制备l-精氨酸中的应用
CN115124605B (zh) * 2022-03-15 2023-08-04 吉林大学 耐高温元件突变体及其在生产氨基酸中的应用
CN114410607A (zh) * 2022-03-22 2022-04-29 上海威高医疗技术发展有限公司 嗜热羧酸酯酶突变体及其应用
KR20230139598A (ko) * 2022-03-28 2023-10-05 씨제이제일제당 (주) O-아세틸 호모세린 생산 미생물 및 이를 이용한 o-아세틸 호모세린 또는 l-메치오닌 생산 방법
KR102952497B1 (ko) * 2022-03-28 2026-04-15 씨제이제일제당 주식회사 O-아세틸 호모세린 생산 미생물 및 이를 이용한 o-아세틸 호모세린 또는 l-메치오닌 생산 방법
EP4526436A1 (de) 2022-05-18 2025-03-26 Evonik Operations GmbH Biotechnologische herstellung von desferrioxaminen und deren analogen
KR102817779B1 (ko) * 2022-05-18 2025-06-09 씨제이제일제당 주식회사 신규한 글루코네이트 리프레서 변이체 및 이를 이용한 l-아르기닌 생산 방법
EP4525842A1 (de) 2022-05-18 2025-03-26 Evonik Operations GmbH Biotechnologische herstellung von bisucaberinen, desferrioxaminen und deren analogen
EP4525843A1 (de) 2022-05-18 2025-03-26 Evonik Operations GmbH Biotechnologische herstellung von monomeren von bisucaberinen, desferrioxaminen und analoga davon
JP7839035B2 (ja) * 2022-06-27 2026-04-01 花王株式会社 芳香族化合物の製造方法
WO2024000364A1 (zh) * 2022-06-30 2024-01-04 江南大学 一种谷氨酸棒杆菌高效突变体及重组菌构建方法与应用
CN115725490B (zh) * 2022-10-19 2024-07-12 天津大学 一种合成与分泌高效电子传递载体吩嗪-1-羧酸的重组希瓦氏菌株构建方法及用途
KR102636672B1 (ko) * 2022-10-31 2024-02-15 대상 주식회사 L-글루탐산을 생산하는 코리네박테리움 속 변이 미생물 및 이를 이용한 l-글루탐산의 생산 방법
CN115960803B (zh) * 2022-11-03 2025-06-27 盐城工学院 一种自主进化系统及其应用
CN115820582B (zh) * 2022-11-29 2025-04-29 浙江大学杭州国际科创中心 一种醇脱氢酶突变体及应用
KR20240108882A (ko) * 2022-12-30 2024-07-10 씨제이제일제당 (주) 신규한 폴리뉴클레오티드 및 이를 이용한 l-알라닌 생산 방법
CN116716314A (zh) * 2023-07-03 2023-09-08 河南农业大学 番茄SlFolB基因在提高植物产量中的应用
KR20250014045A (ko) * 2023-07-18 2025-02-03 한화솔루션 주식회사 신규 1,3-프로판다이올 분비 단백질 및 이를 이용한 1,3-프로판다이올 생산방법
KR20250017178A (ko) * 2023-07-24 2025-02-04 씨제이제일제당 (주) 단백질 변이체 및 이를 이용한 l-라이신 생산 방법
CN117210413B (zh) * 2023-08-04 2026-04-21 湖北文理学院 纹带棒状杆菌噬菌体及其应用
CN119432785B (zh) * 2023-08-07 2026-02-06 中国科学院天津工业生物技术研究所 一种高丝氨酸脱氢酶突变体及其应用
CN117143900B (zh) * 2023-09-04 2025-11-28 绿康生化股份有限公司 敲除amtR基因的产杆菌肽工程菌及其制备方法和应用
CN120058884A (zh) * 2023-11-30 2025-05-30 宁夏伊品生物科技股份有限公司 细胞衰亡相关蛋白在制备l-赖氨酸中的应用
CN117737037B (zh) * 2024-02-07 2024-04-19 中国林业科学研究院高原林业研究所 一种N-乙酰氨基葡萄糖苷酶突变体De266LΔ6及其制备与应用
CN117737038B (zh) * 2024-02-08 2024-04-23 中国林业科学研究院高原林业研究所 一种N-乙酰氨基葡萄糖苷酶突变体De254PΔ5及其制备与应用
CN117737039B (zh) * 2024-02-18 2024-04-23 中国林业科学研究院高原林业研究所 一种N-乙酰氨基葡萄糖苷酶突变体De259AΔ7及其制备与应用
EP4613854A1 (de) 2024-03-05 2025-09-10 Evonik Operations GmbH Verfahren zur fermentativen herstellung von l-lysin unter verwendung von c. glutamicum-stämmen die eine heterologe nicotinamid-nukleotid-transhydrogenase pntab exprimieren und eine erhöhte aktivität einer myo-inositol-permease aufweisen
KR20250166386A (ko) * 2024-05-20 2025-11-28 대상 주식회사 L-시트룰린 또는 l-아르기닌 생산능이 향상된 코리네박테리움 속 미생물 및 이를 이용한 l-시트룰린 또는 l-아르기닌의 생산 방법
KR20260005434A (ko) * 2024-07-02 2026-01-12 코스맥스 주식회사 코리네박테리움 아미콜라툼 sb-1 균주 검출용 조성물 및 이의 용도
CN118561971B (zh) * 2024-08-05 2024-09-27 四川大学华西医院 一种蛋白突变体、纳米孔检测系统及其用途
CN119708180B (zh) * 2024-12-31 2026-03-10 宁夏伊品生物科技股份有限公司 NCgl0762蛋白质及其突变体在生产L-异亮氨酸中的应用
CN119913119B (zh) * 2025-01-14 2025-10-03 浙江工业大学 一种类固醇脱氢酶突变体及其在制备甾体类药物中的应用
CN121294424A (zh) * 2025-10-22 2026-01-09 荣成市瑞祥生物菌有限公司 一种饲料用的复合菌剂及其制备方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE255162T1 (de) 1983-01-13 2003-12-15 Max Planck Gesellschaft Transgene dicotyledone pflanzenzellen und pflanzen
NL8300698A (nl) 1983-02-24 1984-09-17 Univ Leiden Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten.
ATE204017T1 (de) 1984-05-11 2001-08-15 Syngenta Participations Ag Transformation von pflanzenerbgut
IL84459A (en) 1986-12-05 1993-07-08 Agracetus Apparatus and method for the injection of carrier particles carrying genetic material into living cells
US6649379B1 (en) * 1987-06-12 2003-11-18 Massachusetts Institute Of Technology Method and deregulated enzyme for threonine production
WO1988009819A2 (en) * 1987-06-12 1988-12-15 Massachusetts Institute Of Technology C. glutamicum threonine biosynthetic pathway
GB2223754B (en) * 1988-09-12 1992-07-22 Degussa Dna encoding phosphoenolpyruvate carboxylase
JP2928287B2 (ja) 1988-09-29 1999-08-03 協和醗酵工業株式会社 新規ポリペプチド
DE3908201A1 (de) * 1989-03-14 1990-09-27 Degussa Verfahren zur fermentativen herstellung von l-lysin
US5204253A (en) 1990-05-29 1993-04-20 E. I. Du Pont De Nemours And Company Method and apparatus for introducing biological substances into living cells
DE4204361A1 (de) * 1992-02-14 1993-08-19 Degussa Verfahren zur herstellung von l-lysin durch fermentation von coryneformen bakterien
ATE398679T1 (de) 1992-07-07 2008-07-15 Japan Tobacco Inc Verfahren zur transformation einer monokotyledon pflanze
KR0122509B1 (ko) * 1994-06-13 1997-11-24 김정순 L-라이신을 생산하는 미생물
KR0159812B1 (ko) * 1995-12-20 1998-11-16 손경식 코리네박테리움 글루타미컴 씨에이치 77 및 이 균주를 이용한 l-라이신의 제조 방법
JPH1087A (ja) * 1996-06-17 1998-01-06 Ajinomoto Co Inc 発酵法による目的物質の製造法
DE19831609B4 (de) * 1997-10-04 2009-11-12 Evonik Degussa Gmbh Verfahren zur Herstellung von Aminosäuren der Aspartat- und/oder Glutamatfamilie und im Verfahren einsetzbare Mittel
KR100253424B1 (ko) * 1997-12-15 2000-04-15 손 경 식 코리네박테리움 글루타미컴 cj88 및 이 균주를 이용한l-라이신의 제조방법
MXPA01013123A (es) * 1999-06-25 2002-06-21 Basf Ag Genes de corynebacterium glutamicum que codifican proteinas de via metabolica.

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EP2107128A3 (de) 2009-10-14
US7332310B2 (en) 2008-02-19
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KR100970106B1 (ko) 2010-07-15
EP2107128B1 (de) 2012-10-24
EP1108790B1 (de) 2009-09-02
US20020197605A1 (en) 2002-12-26
KR20010082585A (ko) 2001-08-30
DE60042872D1 (de) 2009-10-15
JP4623825B2 (ja) 2011-02-02
EP2107128A2 (de) 2009-10-07
KR100961398B1 (ko) 2010-06-09
EP1108790A2 (de) 2001-06-20

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