ATE442195T1 - Verfahren zur herstellung von mikrokugeln auf basis von ionisch vernetztem polysaccharid - Google Patents

Verfahren zur herstellung von mikrokugeln auf basis von ionisch vernetztem polysaccharid

Info

Publication number
ATE442195T1
ATE442195T1 AT05715458T AT05715458T ATE442195T1 AT E442195 T1 ATE442195 T1 AT E442195T1 AT 05715458 T AT05715458 T AT 05715458T AT 05715458 T AT05715458 T AT 05715458T AT E442195 T1 ATE442195 T1 AT E442195T1
Authority
AT
Austria
Prior art keywords
microspheres
producing
microblades
linked polysaccharide
ionically cross
Prior art date
Application number
AT05715458T
Other languages
English (en)
Inventor
Stefan Kammermeier
Till Merkel
Katharina Schmid
Achim Muller
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE442195T1 publication Critical patent/ATE442195T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B01J13/046—Making microcapsules or microballoons by physical processes, e.g. drying, spraying combined with gelification or coagulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/14—Polymerisation; cross-linking

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
AT05715458T 2004-02-23 2005-02-22 Verfahren zur herstellung von mikrokugeln auf basis von ionisch vernetztem polysaccharid ATE442195T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04003989 2004-02-23
PCT/EP2005/001850 WO2005079970A1 (en) 2004-02-23 2005-02-22 Process for production of ionically crosslinked polysaccharide microspheres

Publications (1)

Publication Number Publication Date
ATE442195T1 true ATE442195T1 (de) 2009-09-15

Family

ID=34878169

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05715458T ATE442195T1 (de) 2004-02-23 2005-02-22 Verfahren zur herstellung von mikrokugeln auf basis von ionisch vernetztem polysaccharid

Country Status (8)

Country Link
US (1) US8206622B2 (de)
EP (1) EP1742729B8 (de)
CN (1) CN100431684C (de)
AT (1) ATE442195T1 (de)
CA (1) CA2557107C (de)
DE (1) DE602005016540D1 (de)
ES (1) ES2334238T3 (de)
WO (1) WO2005079970A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110975774A (zh) * 2019-12-25 2020-04-10 山东圣泉新材料股份有限公司 一种聚合物微球及其制备方法和应用

Families Citing this family (14)

* Cited by examiner, † Cited by third party
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PT103476B (pt) * 2006-05-10 2008-09-19 Univ De Coimbra Processo de produção e isolamento de micro- e nanopartículas poliméricas contendo macromoléculas de natureza hidrofílica e termolábil
WO2009046540A1 (en) * 2007-10-12 2009-04-16 Fio Corporation Flow focusing method and system for forming concentrated volumes of microbeads, and microbeads formed further thereto
EP2174586B1 (de) 2008-10-02 2014-12-10 EyeSense AG Implantierbares Sensorelement
US10010272B2 (en) 2010-05-27 2018-07-03 Profusa, Inc. Tissue-integrating electronic apparatus
CN101880348A (zh) * 2010-07-20 2010-11-10 季生象 一种官能化交联高分子树脂微球的制备方法
WO2012048150A1 (en) 2010-10-06 2012-04-12 Profusa, Inc. Tissue-integrating sensors
CN102847496B (zh) * 2011-07-02 2014-08-13 兰州大学 钙离子交联的聚丙烯酸叔丁酯微囊的制备方法
CN102350407B (zh) * 2011-07-13 2013-04-10 天津开发区合普工贸有限公司 便携式微小粒径气溶胶扩散设备
US11261473B2 (en) * 2014-07-23 2022-03-01 Roche Diabetes Care, Inc. Method and apparatus for generation of microparticles containing immobilized enzyme
CN105538534B (zh) * 2014-10-28 2017-09-26 中宝环保科技（上海）股份有限公司 过滤、调温循环水箱
CN106511995A (zh) * 2016-10-19 2017-03-22 天津佐沐生物科技有限公司 一种水包油包水型疫苗佐剂及其应用
CN108066314A (zh) * 2016-11-17 2018-05-25 中国科学院大连化学物理研究所 一种果胶为壁材的生物微球制备方法及应用
WO2018119400A1 (en) 2016-12-22 2018-06-28 Profusa, Inc. System and single-channel luminescent sensor for and method of determining analyte value
CN119869382A (zh) * 2024-12-26 2025-04-25 深圳市第二人民医院(深圳市转化医学研究院) 一种海藻酸钠凝胶微球的制备装置及制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4352883A (en) * 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US5387522A (en) * 1984-06-01 1995-02-07 Schering Corporation Apparatus having a biphasic spray head for entrapping biological material in a hydrophilic gel
CA1241598A (en) 1984-07-11 1988-09-06 Connaught Laboratories Limited Droplet generation
KR930006431B1 (ko) 1990-10-11 1993-07-16 재단법인 한국화학연구소 약물의 미세캡슐화 방법
DE4426396A1 (de) 1994-07-26 1996-02-01 Ulrich Prof Dr Zimmermann Verfahren zur Herstellung konzentrierter Lösungen von mikroverkapselten Zellen oder von suspendierten Wirkstoffen in mikroverkapselter Form
EP1355630B1 (de) 2000-08-15 2009-11-25 The Board Of Trustees Of The University Of Illinois Verfahren zur herstellung von mikropartikeln
SE0201289D0 (sv) * 2002-04-25 2002-04-25 Amersham Biosciences Ab Manufacture of polysaccharide beads
EP1382341A1 (de) * 2002-07-18 2004-01-21 Cognis Iberia, S.L. Verwendung von Benzoylperoxid und Glyzyrrhetinsäure enthaltende Zusammensetzungen zur Aknebehandlung
EP1502645A1 (de) * 2003-08-01 2005-02-02 The Procter & Gamble Company Mikrokapseln

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110975774A (zh) * 2019-12-25 2020-04-10 山东圣泉新材料股份有限公司 一种聚合物微球及其制备方法和应用

Also Published As

Publication number Publication date
EP1742729A1 (de) 2007-01-17
EP1742729B1 (de) 2009-09-09
CN1933903A (zh) 2007-03-21
CA2557107A1 (en) 2005-09-01
US20070178162A1 (en) 2007-08-02
US8206622B2 (en) 2012-06-26
DE602005016540D1 (de) 2009-10-22
ES2334238T3 (es) 2010-03-08
EP1742729B8 (de) 2010-02-03
WO2005079970A1 (en) 2005-09-01
CA2557107C (en) 2009-04-07
CN100431684C (zh) 2008-11-12
HK1104248A1 (zh) 2008-01-11

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